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Items: 1 to 50 of 107

1.

Disposition of naproxen, naproxen acyl glucuronide and its rearrangement isomers in the isolated perfused rat liver.

Lo A, Addison RS, Hooper WD, Dickinson RG.

Xenobiotica. 2001 Jun;31(6):309-19.

PMID:
11513245
2.

Effect of naproxen co-administration on valproate disposition.

Addison RS, Parker-Scott SL, Hooper WD, Eadie MJ, Dickinson RG.

Biopharm Drug Dispos. 2000 Sep;21(6):235-42.

PMID:
11304722
3.

Evaluation of a pharmacokinetic interaction between remacemide hydrochloride and phenobarbitone in healthy males.

Hooper WD, Eadie MJ, Blakey GE, Lockton JA, Manun'Ebo M.

Br J Clin Pharmacol. 2001 Mar;51(3):249-55.

4.

Population pharmacokinetic modeling of steady state carbamazepine clearance in children, adolescents, and adults.

Reith DM, Hooper WD, Parke J, Charles B.

J Pharmacokinet Pharmacodyn. 2001 Feb;28(1):79-92. Erratum in: J Pharmacokinet Biopharm 2001 Aug;28(4):413.

PMID:
11253616
5.

Steady-state dispositions of valproate and diflunisal alone and coadministered to healthy volunteers.

Addison RS, Parker-Scott SL, Eadie MJ, Hooper WD, Dickinson RG.

Eur J Clin Pharmacol. 2000 Dec;56(9-10):715-21.

PMID:
11214782
6.

The effect of diflunisal on the elimination of triamterene in human volunteers.

Jacob SS, Franklin ME, Dickinson RG, Hooper WD.

Drug Metabol Drug Interact. 2000;16(3):159-71.

PMID:
11116751
7.

Valproate metabolism during valproate-associated hepatotoxicity in a surviving adult patient.

McLaughlin DB, Eadie MJ, Parker-Scott SL, Addison RS, Henderson RD, Hooper WD, Dickinson RG.

Epilepsy Res. 2000 Oct;41(3):259-68.

PMID:
10962217
8.

Phenytoin metabolism by human cytochrome P450: involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation.

Cuttle L, Munns AJ, Hogg NA, Scott JR, Hooper WD, Dickinson RG, Gillam EM.

Drug Metab Dispos. 2000 Aug;28(8):945-50.

PMID:
10901705
9.

Apparent autoinduction of valproate beta-oxidation in humans.

McLaughlin DB, Andrews JA, Hooper WD, Cannell GR, Eadie MJ, Dickinson RG.

Br J Clin Pharmacol. 2000 May;49(5):409-15.

10.
11.
12.

Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation.

Munns AJ, De Voss JJ, Hooper WD, Dickinson RG, Gillam EM.

Chem Res Toxicol. 1997 Sep;10(9):1049-58.

PMID:
9305589
13.

The mechanism of the carbamazepine-valproate interaction in humans.

Bernus I, Dickinson RG, Hooper WD, Eadie MJ.

Br J Clin Pharmacol. 1997 Jul;44(1):21-7.

14.

Anticonvulsant therapy in aged patients. Clinical pharmacokinetic considerations.

Bernus I, Dickinson RG, Hooper WD, Eadie MJ.

Drugs Aging. 1997 Apr;10(4):278-89. Review.

PMID:
9108988
15.

Effects of pregnancy on various pathways of human antiepileptic drug metabolism.

Bernus I, Hooper WD, Dickinson RG, Eadie MJ.

Clin Neuropharmacol. 1997 Feb;20(1):13-21.

PMID:
9037569
16.

Dose-dependent metabolism of carbamazepine in humans.

Bernus I, Dickinson RG, Hooper WD, Eadie MJ.

Epilepsy Res. 1996 Jul;24(3):163-72.

PMID:
8832192
17.

Effect of felbamate on valproic acid disposition in healthy volunteers: inhibition of beta-oxidation.

Hooper WD, Franklin ME, Glue P, Banfield CR, Radwanski E, McLaughlin DB, McIntyre ME, Dickinson RG, Eadie MJ.

Epilepsia. 1996 Jan;37(1):91-7.

PMID:
8603632
18.
19.

Metabolism of carbamazepine and co-administered anticonvulsants during pregnancy.

Bernus I, Hooper WD, Dickinson RG, Eadie MJ.

Epilepsy Res. 1995 May;21(1):65-75.

PMID:
7641678
20.

Expression of cytochrome P450 3A5 in Escherichia coli: effects of 5' modification, purification, spectral characterization, reconstitution conditions, and catalytic activities.

Gillam EM, Guo Z, Ueng YF, Yamazaki H, Cock I, Reilly PE, Hooper WD, Guengerich FP.

Arch Biochem Biophys. 1995 Mar 10;317(2):374-84. Erratum in: Arch Biochem Biophys 1995 Apr 20;318(2):498.

PMID:
7893152
21.

Inhibition of phenobarbitone N-glucosidation by valproate.

Bernus I, Dickinson RG, Hooper WD, Eadie MJ.

Br J Clin Pharmacol. 1994 Nov;38(5):411-6.

22.

Stereoselective hydroxylation of tacrine in rats and humans.

Hooper WD, Pool WF, Woolf TF, Gal J.

Drug Metab Dispos. 1994 Sep-Oct;22(5):719-24.

PMID:
7835223
23.

Urinary excretion of phenobarbitone and its metabolites in chronically treated patients.

Bernus I, Dickinson RG, Hooper WD, Eadie MJ.

Eur J Clin Pharmacol. 1994;46(5):473-5.

PMID:
7957546
24.

Early stage autoinduction of carbamazepine metabolism in humans.

Bernus I, Dickinson RG, Hooper WD, Eadie MJ.

Eur J Clin Pharmacol. 1994;47(4):355-60.

PMID:
7875188
25.

Studies on the renal excretion of the acyl glucuronide, phenolic glucuronide and sulphate conjugates of diflunisal.

Dickinson RG, King AR, McKinnon GE, Hooper WD, Eadie MJ, Herkes GK.

Br J Clin Pharmacol. 1993 Jun;35(6):609-13.

26.

Are enantioselective assay methods necessary for comparative bioavailability studies on racemic drugs?

Hooper WD.

Proc West Pharmacol Soc. 1993;36:167-71. Review. No abstract available.

PMID:
8378373
27.

Enantioselective versus non-enantioselective assays in comparative bioavailability studies with racemic drugs.

Hooper WD, Dickinson RG, Gal J.

Biopharm Drug Dispos. 1992 Jul;13(5):383-7. No abstract available.

PMID:
1498270
28.
29.
30.

Metabolism of diazepam and related benzodiazepines by human liver microsomes.

Hooper WD, Watt JA, McKinnon GE, Reilly PE.

Eur J Drug Metab Pharmacokinet. 1992 Jan-Mar;17(1):51-9.

PMID:
1499597
31.

Phenytoin metabolism during pregnancy.

Eadie MJ, McKinnon GE, Dickinson RG, Hooper WD, Lander CM.

Eur J Clin Pharmacol. 1992;43(4):389-92.

PMID:
1451718
32.
34.

Single oral dose pharmacokinetics and comparative bioavailability of danazol in humans.

Hooper WD, Eadie MJ, Dickinson RG.

Biopharm Drug Dispos. 1991 Nov;12(8):577-82.

PMID:
1801964
35.
36.

Lack of a pharmacokinetic interaction between phenobarbitone and gabapentin.

Hooper WD, Kavanagh MC, Herkes GK, Eadie MJ.

Br J Clin Pharmacol. 1991 Feb;31(2):171-4.

37.
38.

Effect of food on absorption of lomefloxacin.

Hooper WD, Dickinson RG, Eadie MJ.

Antimicrob Agents Chemother. 1990 Sep;34(9):1797-9.

39.

Determination of gabapentin in plasma and urine by capillary column gas chromatography.

Hooper WD, Kavanagh MC, Dickinson RG.

J Chromatogr. 1990 Jul 13;529(1):167-74. No abstract available.

PMID:
2211928
40.
42.

Enantioselective binding of mephobarbital to plasma proteins.

O'Shea NJ, Hooper WD.

Chirality. 1990;2(4):257-62.

PMID:
2083148
43.

The effect of pregnancy in humans on the pharmacokinetics of stable isotope labelled phenytoin.

Dickinson RG, Hooper WD, Wood B, Lander CM, Eadie MJ.

Br J Clin Pharmacol. 1989 Jul;28(1):17-27.

44.

Stereoselective metabolism and pharmacokinetics of racemic methylphenobarbital in humans.

Lim WH, Hooper WD.

Drug Metab Dispos. 1989 Mar-Apr;17(2):212-7.

PMID:
2565213
45.

First dose and steady-state pharmacokinetics of oxcarbazepine and its 10-hydroxy metabolite.

Dickinson RG, Hooper WD, Dunstan PR, Eadie MJ.

Eur J Clin Pharmacol. 1989;37(1):69-74.

PMID:
2591466
46.

Urinary excretion of valproate and some metabolites in chronically treated patients.

Dickinson RG, Hooper WD, Dunstan PR, Eadie MJ.

Ther Drug Monit. 1989;11(2):127-33.

PMID:
2497561
47.

Markers of physical integrity and metabolic viability of the perfused human placental lobule.

Cannell GR, Kluck RM, Hamilton SE, Mortimer RH, Hooper WD, Dickinson RG.

Clin Exp Pharmacol Physiol. 1988 Nov;15(11):837-44.

PMID:
3229008
48.

Disposition of phenytoin and phenobarbitone in the isolated perfused human placenta.

Kluck RM, Cannell GR, Hooper WD, Eadie MJ, Dickinson RG.

Clin Exp Pharmacol Physiol. 1988 Nov;15(11):827-36.

PMID:
3229007
49.

Valproate-associated hepatotoxicity and its biochemical mechanisms.

Eadie MJ, Hooper WD, Dickinson RG.

Med Toxicol Adverse Drug Exp. 1988 Mar-Apr;3(2):85-106. Review.

PMID:
3131628
50.

Further clinical and pharmacokinetic observations on the new anticonvulsant, oxcarbazepine.

Dickinson RG, Hooper WD, Pendlebury SC, Moses D, Eadie MJ.

Clin Exp Neurol. 1988;25:127-33.

PMID:
3077098

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