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Transmembrane signaling on a protocell: Creation of receptor-enzyme chimeras for immunodetection of specific antibodies and antigens.

Su J, Kitaguchi T, Ohmuro-Matsuyama Y, Seah T, Ghadessy FJ, Hoon S, Ueda H.

Sci Rep. 2019 Dec 3;9(1):18189. doi: 10.1038/s41598-019-54539-7.


Better clinical outcome for autologous fat transplant combined with silicone gel prosthesis for breast augmentation: Evidence from meta-analysis.

Hoon SY, Cui CX, Cao J, Hong ZR.

Asian J Surg. 2020 Jan;43(1):166-180. doi: 10.1016/j.asjsur.2019.03.003. Epub 2019 Oct 22.


Correction: Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin.

Wong JH, Alfatah M, Kong KW, Hoon S, Yeo WL, Ching KC, Goh CJH, Zhang MM, Lim YH, Wong FT, Arumugam P.

PLoS One. 2019 Aug 8;14(8):e0221074. doi: 10.1371/journal.pone.0221074. eCollection 2019.


Creation of stable and strictly regulated enzyme switch for signal-on immunodetection of various small antigens.

Su J, Beh C, Ohmuro-Matsuyama Y, Kitaguchi T, Hoon S, Ueda H.

J Biosci Bioeng. 2019 Dec;128(6):677-682. doi: 10.1016/j.jbiosc.2019.05.015. Epub 2019 Jun 21.


HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells.

Ng NHJ, Jasmen JB, Lim CS, Lau HH, Krishnan VG, Kadiwala J, Kulkarni RN, Ræder H, Vallier L, Hoon S, Teo AKK.

iScience. 2019 Jun 28;16:192-205. doi: 10.1016/j.isci.2019.05.032. Epub 2019 May 27.


Chemogenomic profiling in yeast reveals antifungal mode-of-action of polyene macrolactam auroramycin.

Wong JH, Alfatah M, Kong KW, Hoon S, Yeo WL, Ching KC, Jie Hui Goh C, Zhang MM, Lim YH, Wong FT, Arumugam P.

PLoS One. 2019 Jun 10;14(6):e0218189. doi: 10.1371/journal.pone.0218189. eCollection 2019. Erratum in: PLoS One. 2019 Aug 8;14(8):e0221074.


Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo.

Xue Y, Barker N, Hoon S, He P, Thakur T, Abdeen SR, Maruthappan P, Ghadessy FJ, Lane DP.

Cancer Res. 2019 Jul 15;79(14):3595-3607. doi: 10.1158/0008-5472.CAN-18-3744. Epub 2019 May 28.


Applications of Photonics in Agriculture Sector: A Review.

Yeong TJ, Pin Jern K, Yao LK, Hannan MA, Hoon STG.

Molecules. 2019 May 27;24(10). pii: E2025. doi: 10.3390/molecules24102025. Review.


Characterization of Cas proteins for CRISPR-Cas editing in streptomycetes.

Yeo WL, Heng E, Tan LL, Lim YW, Lim YH, Hoon S, Zhao H, Zhang MM, Wong FT.

Biotechnol Bioeng. 2019 Sep;116(9):2330-2338. doi: 10.1002/bit.27021. Epub 2019 May 30.


Chemical-genetic interaction landscape of mono-(2-ethylhexyl)-phthalate using chemogenomic profiling in yeast.

Alfatah M, Wong JH, Kong KW, Utama F, Hoon S, Arumugam P.

Chemosphere. 2019 Aug;228:219-231. doi: 10.1016/j.chemosphere.2019.04.100. Epub 2019 Apr 15.


A diecast mineralization process forms the tough mantis shrimp dactyl club.

Amini S, Tadayon M, Loke JJ, Kumar A, Kanagavel D, Le Ferrand H, Duchamp M, Raida M, Sobota RM, Chen L, Hoon S, Miserez A.

Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8685-8692. doi: 10.1073/pnas.1816835116. Epub 2019 Apr 11.


Hypoculoside, a sphingoid base-like compound from Acremonium disrupts the membrane integrity of yeast cells.

Alfatah M, Wong JH, Nge CE, Kong KW, Low KN, Leong CY, Crasta S, Munusamy M, Chang AML, Hoon S, Ng SB, Kanagasundaram Y, Arumugam P.

Sci Rep. 2019 Jan 24;9(1):710. doi: 10.1038/s41598-018-35979-z.


Supramolecular propensity of suckerin proteins is driven by β-sheets and aromatic interactions as revealed by solution NMR.

Kumar A, Mohanram H, Kong KW, Goh R, Hoon S, Lescar J, Miserez A.

Biomater Sci. 2018 Aug 21;6(9):2440-2447. doi: 10.1039/c8bm00556g.


JNK2 silencing and caspase-9 activation by hyperosmotic polymer inhibits tumor progression.

Garg P, Pandey S, Hoon S, Jang KJ, Lee MC, Choung YH, Choung PH, Chung JH.

Int J Biol Macromol. 2018 Dec;120(Pt B):2215-2224. doi: 10.1016/j.ijbiomac.2018.07.019. Epub 2018 Jul 10.


A novel λ integrase-mediated seamless vector transgenesis platform for therapeutic protein expression.

Makhija H, Roy S, Hoon S, Ghadessy FJ, Wong D, Jaiswal R, Campana D, Dröge P.

Nucleic Acids Res. 2018 Sep 19;46(16):e99. doi: 10.1093/nar/gky500.


Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR-Cas9 Activation.

Lim YH, Wong FT, Yeo WL, Ching KC, Lim YW, Heng E, Chen S, Tsai DJ, Lauderdale TL, Shia KS, Ho YS, Hoon S, Ang EL, Zhang MM, Zhao H.

Chembiochem. 2018 May 25. doi: 10.1002/cbic.201800266. [Epub ahead of print]


An anti-barotrauma system for preventing barotrauma during hyperbaric oxygen therapy.

Song M, Hoon SJ, Shin TM.

Undersea Hyperb Med. 2018 Jan-Feb;45(1):19-25.


Structure-activity relationship studies of ultra-short peptides with potent activities against fluconazole-resistant Candida albicans.

Ng SMS, Yap JM, Lau QY, Ng FM, Ong EHQ, Barkham T, Teo JWP, Alfatah M, Kong KW, Hoon S, Arumugam P, Hill J, Brian Chia CS.

Eur J Med Chem. 2018 Apr 25;150:479-490. doi: 10.1016/j.ejmech.2018.03.027. Epub 2018 Mar 9.


Circulating Polyunsaturated Fatty Acids as Biomarkers for Dietary Intake across Subgroups: The CODAM and Hoorn Studies.

Wanders AJ, Alssema M, De Hoon SEM, Feskens EJM, van Woudenbergh GJ, van der Kallen CJ, Zock PL, Refsum H, Drevon CA, Elshorbagy A, Schalkwijk CG, Stehouwer CDA, Dekker JM, van Greevenbroek MMJ.

Ann Nutr Metab. 2018;72(2):117-125. doi: 10.1159/000486244. Epub 2018 Jan 25.


Skin Commensal Malassezia globosa Secreted Protease Attenuates Staphylococcus aureus Biofilm Formation.

Li H, Goh BN, Teh WK, Jiang Z, Goh JPZ, Goh A, Wu G, Hoon SS, Raida M, Camattari A, Yang L, O'Donoghue AJ, Dawson TL Jr.

J Invest Dermatol. 2018 May;138(5):1137-1145. doi: 10.1016/j.jid.2017.11.034. Epub 2017 Dec 12.


Adverse events recording in electronic health record systems in primary care.

de Hoon SEM, Hek K, van Dijk L, Verheij RA.

BMC Med Inform Decis Mak. 2017 Dec 6;17(1):163. doi: 10.1186/s12911-017-0565-7.


Hypoxia due to positive pressure ventilation in Edwards' syndrome: A case report.

Hoon SK, Kang SW, Kwak SH, Kim J.

J Int Med Res. 2018 Feb;46(2):895-900. doi: 10.1177/0300060517734680. Epub 2017 Nov 10.


Metal pollutants in Indian continental coastal marine sediment along a 3700km transect: An electron paramagnetic resonance spectroscopic study.

Alagarsamy R, Hoon SR.

Sci Total Environ. 2018 Jan 15;612:26-38. doi: 10.1016/j.scitotenv.2017.08.065. Epub 2017 Sep 1.


Preventing mussel adhesion using lubricant-infused materials.

Amini S, Kolle S, Petrone L, Ahanotu O, Sunny S, Sutanto CN, Hoon S, Cohen L, Weaver JC, Aizenberg J, Vogel N, Miserez A.

Science. 2017 Aug 18;357(6352):668-673. doi: 10.1126/science.aai8977.


Patient Satisfaction and Its Influencing Factors of Microtia Reconstruction Using Autologous Cartilage.

Cui C, Hoon SY, Zhang R, Zhang Q, Xu Z, Xu F, Li D, Li Y.

Aesthetic Plast Surg. 2017 Oct;41(5):1106-1114. doi: 10.1007/s00266-017-0907-y. Epub 2017 Jun 22.


SGBS cells as a model of human adipocyte browning: A comprehensive comparative study with primary human white subcutaneous adipocytes.

Yeo CR, Agrawal M, Hoon S, Shabbir A, Shrivastava MK, Huang S, Khoo CM, Chhay V, Yassin MS, Tai ES, Vidal-Puig A, Toh SA.

Sci Rep. 2017 Jun 22;7(1):4031. doi: 10.1038/s41598-017-04369-2.


Hierarchical Assembly of Tough Bioelastomeric Egg Capsules is Mediated by a Bundling Protein.

Loke JJ, Kumar A, Hoon S, Verma C, Miserez A.

Biomacromolecules. 2017 Mar 13;18(3):931-942. doi: 10.1021/acs.biomac.6b01810. Epub 2017 Feb 28.


Kinetic Controlled Tag-Catcher Interactions for Directed Covalent Protein Assembly.

Tan LL, Hoon SS, Wong FT.

PLoS One. 2016 Oct 26;11(10):e0165074. doi: 10.1371/journal.pone.0165074. eCollection 2016.


Erratum. Retinoic Acid Mediates Visceral-Specific Adipogenic Defects of Human Adipose-Derived Stem Cells. Diabetes 2016;65:1164-1178.

Takeda K, Sriram S, Chan XH, Ong WK, Yeo CR, Tan B, Lee SA, Kong KV, Hoon S, Jiang H, Yuen JJ, Perumal J, Agrawal M, Vaz C, So J, Shabbir A, Blaner WS, Olivo M, Han W, Tanavde V, Toh SA, Sugii S.

Diabetes. 2016 Sep;65(9):2816. doi: 10.2337/db16-er09. No abstract available.


Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses.

Kapeli K, Pratt GA, Vu AQ, Hutt KR, Martinez FJ, Sundararaman B, Batra R, Freese P, Lambert NJ, Huelga SC, Chun SJ, Liang TY, Chang J, Donohue JP, Shiue L, Zhang J, Zhu H, Cambi F, Kasarskis E, Hoon S, Ares M Jr, Burge CB, Ravits J, Rigo F, Yeo GW.

Nat Commun. 2016 Jul 5;7:12143. doi: 10.1038/ncomms12143.


Retinoic Acid Mediates Visceral-Specific Adipogenic Defects of Human Adipose-Derived Stem Cells.

Takeda K, Sriram S, Chan XH, Ong WK, Yeo CR, Tan B, Lee SA, Kong KV, Hoon S, Jiang H, Yuen JJ, Perumal J, Agrawal M, Vaz C, So J, Shabbir A, Blaner WS, Olivo M, Han W, Tanavde V, Toh SA, Sugii S.

Diabetes. 2016 May;65(5):1164-78. doi: 10.2337/db15-1315. Epub 2016 Mar 2. Erratum in: Diabetes. 2016 Sep;65(9):2816.


Healthy eating and survival among elderly men with and without cardiovascular-metabolic diseases.

Sijtsma FP, Soedamah-Muthu SS, de Hoon SE, Jacobs DR Jr, Kromhout D.

Nutr Metab Cardiovasc Dis. 2015 Dec;25(12):1117-24. doi: 10.1016/j.numecd.2015.08.008. Epub 2015 Sep 21.


Stable Formation of Gold Nanoparticles onto Redox-Active Solid Biosubstrates Made of Squid Suckerin Proteins.

Cantaert B, Ding D, Rieu C, Petrone L, Hoon S, Kock KH, Miserez A.

Macromol Rapid Commun. 2015 Nov;36(21):1877-1883. doi: 10.1002/marc.201500218. Epub 2015 Jul 14.


Functional VEGFA knockdown with artificial 3'-tailed mirtrons defined by 5' splice site and branch point.

Kock KH, Kong KW, Hoon S, Seow Y.

Nucleic Acids Res. 2015 Jul 27;43(13):6568-78. doi: 10.1093/nar/gkv617. Epub 2015 Jun 18.


Infiltration of chitin by protein coacervates defines the squid beak mechanical gradient.

Tan Y, Hoon S, Guerette PA, Wei W, Ghadban A, Hao C, Miserez A, Waite JH.

Nat Chem Biol. 2015 Jul;11(7):488-95. doi: 10.1038/nchembio.1833. Epub 2015 Jun 8.


PDX1 binds and represses hepatic genes to ensure robust pancreatic commitment in differentiating human embryonic stem cells.

Teo AK, Tsuneyoshi N, Hoon S, Tan EK, Stanton LW, Wright CV, Dunn NR.

Stem Cell Reports. 2015 Apr 14;4(4):578-90. doi: 10.1016/j.stemcr.2015.02.015. Epub 2015 Apr 2.


Identification and Characterization of an eIF4e DNA Aptamer That Inhibits Proliferation With High Throughput Sequencing.

Guo WM, Kong KW, Brown CJ, Quah ST, Yeo HL, Hoon S, Seow Y.

Mol Ther Nucleic Acids. 2014 Dec 16;3:e217. doi: 10.1038/mtna.2014.70.


Establishment of a novel whole animal HTS technology platform for melioidosis drug discovery.

Lakshmanan U, Yap A, Fulwood J, Yichun L, Hoon SS, Lim J, Ting A, Sem XH, Kreisberg JF, Tan P, Tan G, Flotow H.

Comb Chem High Throughput Screen. 2014;17(9):790-803.


Biomimetic production of silk-like recombinant squid sucker ring teeth proteins.

Ding D, Guerette PA, Hoon S, Kong KW, Cornvik T, Nilsson M, Kumar A, Lescar J, Miserez A.

Biomacromolecules. 2014 Sep 8;15(9):3278-89. doi: 10.1021/bm500670r. Epub 2014 Aug 5.


Nanoconfined β-sheets mechanically reinforce the supra-biomolecular network of robust squid Sucker Ring Teeth.

Guerette PA, Hoon S, Ding D, Amini S, Masic A, Ravi V, Venkatesh B, Weaver JC, Miserez A.

ACS Nano. 2014 Jul 22;8(7):7170-9.


The dsRBP and inactive editor ADR-1 utilizes dsRNA binding to regulate A-to-I RNA editing across the C. elegans transcriptome.

Washburn MC, Kakaradov B, Sundararaman B, Wheeler E, Hoon S, Yeo GW, Hundley HA.

Cell Rep. 2014 Feb 27;6(4):599-607. doi: 10.1016/j.celrep.2014.01.011. Epub 2014 Feb 6.


Elephant shark genome provides unique insights into gnathostome evolution.

Venkatesh B, Lee AP, Ravi V, Maurya AK, Lian MM, Swann JB, Ohta Y, Flajnik MF, Sutoh Y, Kasahara M, Hoon S, Gangu V, Roy SW, Irimia M, Korzh V, Kondrychyn I, Lim ZW, Tay BH, Tohari S, Kong KW, Ho S, Lorente-Galdos B, Quilez J, Marques-Bonet T, Raney BJ, Ingham PW, Tay A, Hillier LW, Minx P, Boehm T, Wilson RK, Brenner S, Warren WC.

Nature. 2014 Jan 9;505(7482):174-9. doi: 10.1038/nature12826. Erratum in: Nature. 2014 Sep 25;513(7519):574.


Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges.

Lovci MT, Ghanem D, Marr H, Arnold J, Gee S, Parra M, Liang TY, Stark TJ, Gehman LT, Hoon S, Massirer KB, Pratt GA, Black DL, Gray JW, Conboy JG, Yeo GW.

Nat Struct Mol Biol. 2013 Dec;20(12):1434-42. doi: 10.1038/nsmb.2699. Epub 2013 Nov 10.


Accelerating the design of biomimetic materials by integrating RNA-seq with proteomics and materials science.

Guerette PA, Hoon S, Seow Y, Raida M, Masic A, Wong FT, Ho VH, Kong KW, Demirel MC, Pena-Francesch A, Amini S, Tay GZ, Ding D, Miserez A.

Nat Biotechnol. 2013 Oct;31(10):908-15. doi: 10.1038/nbt.2671. Epub 2013 Sep 8.


LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance.

Wilbert ML, Huelga SC, Kapeli K, Stark TJ, Liang TY, Chen SX, Yan BY, Nathanson JL, Hutt KR, Lovci MT, Kazan H, Vu AQ, Massirer KB, Morris Q, Hoon S, Yeo GW.

Mol Cell. 2012 Oct 26;48(2):195-206. doi: 10.1016/j.molcel.2012.08.004. Epub 2012 Sep 6.


The methodology of the GUSTO cohort study: a novel approach in studying pediatric allergy.

Soh SE, Lee SS, Hoon SW, Tan MY, Goh A, Lee BW, Shek LP, Teoh OH, Kwek K, Saw SM, Godfrey K, Chong YS, Gluckman P, van Bever HP.

Asia Pac Allergy. 2012 Apr;2(2):144-8. doi: 10.5415/apallergy.2012.2.2.144. Epub 2012 Apr 23.


Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins.

Huelga SC, Vu AQ, Arnold JD, Liang TY, Liu PP, Yan BY, Donohue JP, Shiue L, Hoon S, Brenner S, Ares M Jr, Yeo GW.

Cell Rep. 2012 Feb 23;1(2):167-78.


A global perspective of the genetic basis for carbonyl stress resistance.

Hoon S, Gebbia M, Costanzo M, Davis RW, Giaever G, Nislow C.

G3 (Bethesda). 2011 Aug;1(3):219-31. doi: 10.1534/g3.111.000505. Epub 2011 Aug 1.

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