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Items: 1 to 50 of 146

1.

Imaging HDACs In Vivo: Cross-Validation of the [11C]Martinostat Radioligand in the Pig Brain.

Donovan LL, Magnussen JH, Dyssegaard A, Lehel S, Hooker JM, Knudsen GM, Hansen HD.

Mol Imaging Biol. 2019 Jul 9. doi: 10.1007/s11307-019-01403-9. [Epub ahead of print]

PMID:
31290052
2.

Neuroepigenetic signatures of age and sex in the living human brain.

Gilbert TM, Zürcher NR, Catanese MC, Tseng CJ, Di Biase MA, Lyall AE, Hightower BG, Parmar AJ, Bhanot A, Wu CJ, Hibert ML, Kim M, Mahmood U, Stufflebeam SM, Schroeder FA, Wang C, Roffman JL, Holt DJ, Greve DN, Pasternak O, Kubicki M, Wey HY, Hooker JM.

Nat Commun. 2019 Jul 3;10(1):2945. doi: 10.1038/s41467-019-11031-0.

3.

Class I and II histone deacetylase expression is not altered in human amyotrophic lateral sclerosis: Neuropathological and positron emission tomography molecular neuroimaging evidence.

Dios AM, Babu S, Granucci EJ, Mueller KA, Mills AN, Alshikho MJ, Zürcher NR, Cernasov P, Gilbert TM, Glass JD, Berry JD, Atassi N, Hooker JM, Sadri-Vakili G.

Muscle Nerve. 2019 Jun 26. doi: 10.1002/mus.26620. [Epub ahead of print]

PMID:
31241177
4.

Human Positron Emission Tomography Neuroimaging.

Hooker JM, Carson RE.

Annu Rev Biomed Eng. 2019 Jun 4;21:551-581. doi: 10.1146/annurev-bioeng-062117-121056.

PMID:
31167104
5.

The neuroinflammatory component of negative affect in patients with chronic pain.

Albrecht DS, Kim M, Akeju O, Torrado-Carvajal A, Edwards RR, Zhang Y, Bergan C, Protsenko E, Kucyi A, Wasan AD, Hooker JM, Napadow V, Loggia ML.

Mol Psychiatry. 2019 May 28. doi: 10.1038/s41380-019-0433-1. [Epub ahead of print]

PMID:
31138890
6.

A Protocol for Sedation Free MRI and PET Imaging in Adults with Autism Spectrum Disorder.

Smith CJ, Bhanot A, Norman E, Mullett JE, Bilbo SD, McDougle CJ, Zürcher NR, Hooker JM.

J Autism Dev Disord. 2019 Jul;49(7):3036-3044. doi: 10.1007/s10803-019-04010-3.

PMID:
31004246
7.

Editors' Favorites: Best of 2018.

Lindsley CW, Abbott C, Andrews AM, Hooker JM, Zhou J.

ACS Chem Neurosci. 2019 Jan 16;10(1):1-4. doi: 10.1021/acschemneuro.8b00717. No abstract available.

PMID:
30990663
8.

Imaging of neuroinflammation in migraine with aura: A [11C]PBR28 PET/MRI study.

Albrecht DS, Mainero C, Ichijo E, Ward N, Granziera C, Zürcher NR, Akeju O, Bonnier G, Price J, Hooker JM, Napadow V, Loggia ML, Hadjikhani N.

Neurology. 2019 Apr 23;92(17):e2038-e2050. doi: 10.1212/WNL.0000000000007371. Epub 2019 Mar 27.

PMID:
30918090
9.

PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia.

Gilbert TM, Zürcher NR, Wu CJ, Bhanot A, Hightower BG, Kim M, Albrecht DS, Wey HY, Schroeder FA, Rodriguez-Thompson A, Morin TM, Hart KL, Pellegrini AM, Riley MM, Wang C, Stufflebeam SM, Haggarty SJ, Holt DJ, Loggia ML, Perlis RH, Brown HE, Roffman JL, Hooker JM.

J Clin Invest. 2019 Jan 2;129(1):364-372. doi: 10.1172/JCI123743. Epub 2018 Dec 10.

10.

Adamantane/Cucurbituril: A Potential Pretargeted Imaging Strategy in Immuno-PET.

Strebl MG, Yang J, Isaacs L, Hooker JM.

Mol Imaging. 2018 Jan-Dec;17:1536012118799838. doi: 10.1177/1536012118799838.

11.

Response to Comment on "In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates".

Sander CY, Schoenberger M, Hooker JM.

ACS Chem Neurosci. 2019 Jan 16;10(1):773-775. doi: 10.1021/acschemneuro.8b00423. Epub 2018 Oct 11. No abstract available.

PMID:
30346705
12.

Brain glial activation in fibromyalgia - A multi-site positron emission tomography investigation.

Albrecht DS, Forsberg A, Sandström A, Bergan C, Kadetoff D, Protsenko E, Lampa J, Lee YC, Höglund CO, Catana C, Cervenka S, Akeju O, Lekander M, Cohen G, Halldin C, Taylor N, Kim M, Hooker JM, Edwards RR, Napadow V, Kosek E, Loggia ML.

Brain Behav Immun. 2019 Jan;75:72-83. doi: 10.1016/j.bbi.2018.09.018. Epub 2018 Sep 14.

13.

Discrepancies in Kappa Opioid Agonist Binding Revealed through PET Imaging.

Placzek MS, Schroeder FA, Che T, Wey HY, Neelamegam R, Wang C, Roth BL, Hooker JM.

ACS Chem Neurosci. 2019 Jan 16;10(1):384-395. doi: 10.1021/acschemneuro.8b00293. Epub 2018 Oct 17.

PMID:
30212182
14.

Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity.

Porter NJ, Osko JD, Diedrich D, Kurz T, Hooker JM, Hansen FK, Christianson DW.

J Med Chem. 2018 Sep 13;61(17):8054-8060. doi: 10.1021/acs.jmedchem.8b01013. Epub 2018 Aug 17.

PMID:
30118224
15.

Integrated imaging of [11C]-PBR28 PET, MR diffusion and magnetic resonance spectroscopy 1H-MRS in amyotrophic lateral sclerosis.

Ratai EM, Alshikho MJ, Zürcher NR, Loggia ML, Cebulla CL, Cernasov P, Reynolds B, Fish J, Seth R, Babu S, Paganoni S, Hooker JM, Atassi N.

Neuroimage Clin. 2018 Aug 9;20:357-364. doi: 10.1016/j.nicl.2018.08.007. eCollection 2018.

16.

Specific 18F-FDHT Accumulation in Human Prostate Cancer Xenograft Murine Models Is Facilitated by Prebinding to Sex Hormone-Binding Globulin.

Larimer BM, Dubois F, Bloch E, Nesti S, Placzek M, Zadra G, Hooker JM, Loda M, Mahmood U.

J Nucl Med. 2018 Oct;59(10):1538-1543. doi: 10.2967/jnumed.118.208785. Epub 2018 May 31.

PMID:
29853654
17.

Integrated magnetic resonance imaging and [11 C]-PBR28 positron emission tomographic imaging in amyotrophic lateral sclerosis.

Alshikho MJ, Zürcher NR, Loggia ML, Cernasov P, Reynolds B, Pijanowski O, Chonde DB, Izquierdo Garcia D, Mainero C, Catana C, Chan J, Babu S, Paganoni S, Hooker JM, Atassi N.

Ann Neurol. 2018 Jun;83(6):1186-1197. doi: 10.1002/ana.25251.

18.

Neuroinflammation in Huntington's Disease: New Insights with 11C-PBR28 PET/MRI.

Lois C, González I, Izquierdo-García D, Zürcher NR, Wilkens P, Loggia ML, Hooker JM, Rosas HD.

ACS Chem Neurosci. 2018 Nov 21;9(11):2563-2571. doi: 10.1021/acschemneuro.8b00072. Epub 2018 May 17.

PMID:
29719953
19.

Correction to In Vivo Imaging of Human Neuroinflammation.

Albrecht DS, Granziera C, Hooker JM, Loggia ML.

ACS Chem Neurosci. 2018 Jun 20;9(6):1515. doi: 10.1021/acschemneuro.8b00188. Epub 2018 Apr 30. No abstract available.

PMID:
29708334
20.

Site-selective 18F fluorination of unactivated C-H bonds mediated by a manganese porphyrin.

Liu W, Huang X, Placzek MS, Krska SW, McQuade P, Hooker JM, Groves JT.

Chem Sci. 2017 Dec 5;9(5):1168-1172. doi: 10.1039/c7sc04545j. eCollection 2018 Feb 7.

21.

Functionally Biased D2R Antagonists: Targeting the β-Arrestin Pathway to Improve Antipsychotic Treatment.

Weïwer M, Xu Q, Gale JP, Lewis M, Campbell AJ, Schroeder FA, Van de Bittner GC, Walk M, Amaya A, Su P, D Ordevic L, Sacher JR, Skepner A, Fei D, Dennehy K, Nguyen S, Faloon PW, Perez J, Cottrell JR, Liu F, Palmer M, Pan JQ, Hooker JM, Zhang YL, Scolnick E, Wagner FF, Holson EB.

ACS Chem Biol. 2018 Apr 20;13(4):1038-1047. doi: 10.1021/acschembio.8b00168. Epub 2018 Mar 14.

PMID:
29485852
22.

Neuroinflammation of the spinal cord and nerve roots in chronic radicular pain patients.

Albrecht DS, Ahmed SU, Kettner NW, Borra RJH, Cohen-Adad J, Deng H, Houle TT, Opalacz A, Roth SA, Melo MFV, Chen L, Mao J, Hooker JM, Loggia ML, Zhang Y.

Pain. 2018 May;159(5):968-977. doi: 10.1097/j.pain.0000000000001171.

23.

Editors' Favorites of 2017.

Lindsley CW, Cunningham KA, Hooker JM, Andrews AM.

ACS Chem Neurosci. 2018 Jan 17;9(1):1-4. doi: 10.1021/acschemneuro.8b00001. No abstract available.

PMID:
29338186
24.

Metal Protein-Attenuating Compound for PET Neuroimaging: Synthesis and Preclinical Evaluation of [11C]PBT2.

Krishnan HS, Bernard-Gauthier V, Placzek MS, Dahl K, Narayanaswami V, Livni E, Chen Z, Yang J, Collier TL, Ran C, Hooker JM, Liang SH, Vasdev N.

Mol Pharm. 2018 Feb 5;15(2):695-702. doi: 10.1021/acs.molpharmaceut.7b00936. Epub 2018 Jan 22.

PMID:
29298483
25.

Imaging of glia activation in people with primary lateral sclerosis.

Paganoni S, Alshikho MJ, Zürcher NR, Cernasov P, Babu S, Loggia ML, Chan J, Chonde DB, Garcia DI, Catana C, Mainero C, Rosen BR, Cudkowicz ME, Hooker JM, Atassi N.

Neuroimage Clin. 2017 Oct 25;17:347-353. doi: 10.1016/j.nicl.2017.10.024. eCollection 2018.

26.

In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates.

Schoenberger M, Schroeder FA, Placzek MS, Carter RL, Rosen BR, Hooker JM, Sander CY.

ACS Chem Neurosci. 2018 Feb 21;9(2):298-305. doi: 10.1021/acschemneuro.7b00327. Epub 2017 Nov 14.

27.

Positron Emission Tomography Assessment of the Intranasal Delivery Route for Orexin A.

Van de Bittner GC, Van de Bittner KC, Wey HY, Rowe W, Dharanipragada R, Ying X, Hurst W, Giovanni A, Alving K, Gupta A, Hoekman J, Hooker JM.

ACS Chem Neurosci. 2018 Feb 21;9(2):358-368. doi: 10.1021/acschemneuro.7b00357. Epub 2017 Nov 7.

PMID:
29035509
28.

HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination.

Strebl MG, Campbell AJ, Zhao WN, Schroeder FA, Riley MM, Chindavong PS, Morin TM, Haggarty SJ, Wagner FF, Ritter T, Hooker JM.

ACS Cent Sci. 2017 Sep 27;3(9):1006-1014. doi: 10.1021/acscentsci.7b00274. Epub 2017 Sep 6.

29.

18F-Deoxyfluorination of Phenols via Ru π-Complexes.

Beyzavi MH, Mandal D, Strebl MG, Neumann CN, D'Amato EM, Chen J, Hooker JM, Ritter T.

ACS Cent Sci. 2017 Sep 27;3(9):944-948. doi: 10.1021/acscentsci.7b00195. Epub 2017 Aug 3.

30.

Functional Characterization of 5-HT1B Receptor Drugs in Nonhuman Primates Using Simultaneous PET-MR.

Hansen HD, Mandeville JB, Sander CY, Hooker JM, Catana C, Rosen BR, Knudsen GM.

J Neurosci. 2017 Nov 1;37(44):10671-10678. doi: 10.1523/JNEUROSCI.1971-17.2017. Epub 2017 Oct 2.

31.

Pseudoreference Regions for Glial Imaging with 11C-PBR28: Investigation in 2 Clinical Cohorts.

Albrecht DS, Normandin MD, Shcherbinin S, Wooten DW, Schwarz AJ, Zürcher NR, Barth VN, Guehl NJ, Akeju O, Atassi N, Veronese M, Turkheimer F, Hooker JM, Loggia ML.

J Nucl Med. 2018 Jan;59(1):107-114. doi: 10.2967/jnumed.116.178335. Epub 2017 Aug 17.

32.

Effects of flow changes on radiotracer binding: Simultaneous measurement of neuroreceptor binding and cerebral blood flow modulation.

Sander CY, Mandeville JB, Wey HY, Catana C, Hooker JM, Rosen BR.

J Cereb Blood Flow Metab. 2019 Jan;39(1):131-146. doi: 10.1177/0271678X17725418. Epub 2017 Aug 17.

PMID:
28816571
33.

Classics in Neuroimaging: Imaging the Dopaminergic Pathway with PET.

Kanthan M, Cumming P, Hooker JM, Vasdev N.

ACS Chem Neurosci. 2017 Sep 20;8(9):1817-1819. doi: 10.1021/acschemneuro.7b00252. Epub 2017 Jul 18.

PMID:
28719177
34.

[11C]Cyanation of arylboronic acids in aqueous solutions.

Ma L, Placzek MS, Hooker JM, Vasdev N, Liang SH.

Chem Commun (Camb). 2017 Jun 21;53(49):6597-6600. doi: 10.1039/c7cc02886e. Epub 2017 Jun 5.

35.

Direct 11CN-Labeling of Unprotected Peptides via Palladium-Mediated Sequential Cross-Coupling Reactions.

Zhao W, Lee HG, Buchwald SL, Hooker JM.

J Am Chem Soc. 2017 May 31;139(21):7152-7155. doi: 10.1021/jacs.7b02761. Epub 2017 May 17.

36.

Amylin receptor ligands reduce the pathological cascade of Alzheimer's disease.

Zhu H, Xue X, Wang E, Wallack M, Na H, Hooker JM, Kowall N, Tao Q, Stein TD, Wolozin B, Qiu WQ.

Neuropharmacology. 2017 Jun;119:170-181. doi: 10.1016/j.neuropharm.2017.03.030. Epub 2017 Mar 28.

37.

Development of [18F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging.

Hu K, Patnaik D, Collier TL, Lee KN, Gao H, Swoyer MR, Rotstein BH, Krishnan HS, Liang SH, Wang J, Yan Z, Hooker JM, Vasdev N, Haggarty SJ, Ngai MY.

ACS Med Chem Lett. 2017 Feb 2;8(3):287-292. doi: 10.1021/acsmedchemlett.6b00405. eCollection 2017 Mar 9.

38.

Imaging cardiac SCN5A using the novel F-18 radiotracer radiocaine.

Hooker JM, Strebl MG, Schroeder FA, Wey HY, Ambardekar AV, McKinsey TA, Schoenberger M.

Sci Rep. 2017 Feb 16;7:42136. doi: 10.1038/srep42136.

39.

Dopamine in the medial amygdala network mediates human bonding.

Atzil S, Touroutoglou A, Rudy T, Salcedo S, Feldman R, Hooker JM, Dickerson BC, Catana C, Barrett LF.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2361-2366. doi: 10.1073/pnas.1612233114. Epub 2017 Feb 13.

40.

Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts.

Schuetze KB, Stratton MS, Blakeslee WW, Wempe MF, Wagner FF, Holson EB, Kuo YM, Andrews AJ, Gilbert TM, Hooker JM, McKinsey TA.

J Pharmacol Exp Ther. 2017 Apr;361(1):140-150. doi: 10.1124/jpet.116.237701. Epub 2017 Feb 7.

41.

PET/MRI in the Presence of Metal Implants: Completion of the Attenuation Map from PET Emission Data.

Fuin N, Pedemonte S, Catalano OA, Izquierdo-Garcia D, Soricelli A, Salvatore M, Heberlein K, Hooker JM, Van Leemput K, Catana C.

J Nucl Med. 2017 May;58(5):840-845. doi: 10.2967/jnumed.116.183343. Epub 2017 Jan 26.

42.

Nasal neuron PET imaging quantifies neuron generation and degeneration.

Van de Bittner GC, Riley MM, Cao L, Ehses J, Herrick SP, Ricq EL, Wey HY, O'Neill MJ, Ahmed Z, Murray TK, Smith JE, Wang C, Schroeder FA, Albers MW, Hooker JM.

J Clin Invest. 2017 Feb 1;127(2):681-694. doi: 10.1172/JCI89162. Epub 2017 Jan 23.

43.

Editors' Favorites of 2016.

Lindsley CW, Hooker JM, Cunningham KA, Andrews AM.

ACS Chem Neurosci. 2017 Jan 18;8(1):1-3. doi: 10.1021/acschemneuro.6b00461. No abstract available.

PMID:
28095678
44.

Reply.

Herranz E, Hooker JM, Izquierdo-Garcia D, Loggia ML, Mainero C.

Ann Neurol. 2017 Feb;81(2):324-325. doi: 10.1002/ana.24865. Epub 2017 Jan 23. No abstract available.

PMID:
28032651
45.

Bridging the gaps in 18F PET tracer development.

Campbell MG, Mercier J, Genicot C, Gouverneur V, Hooker JM, Ritter T.

Nat Chem. 2016 Dec 20;9(1):1-3. doi: 10.1038/nchem.2693. No abstract available.

PMID:
27995923
46.

Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia.

Schroeder FA, Gilbert TM, Feng N, Taillon BD, Volkow ND, Innis RB, Hooker JM, Lipska BK.

ACS Chem Neurosci. 2017 Mar 15;8(3):662-668. doi: 10.1021/acschemneuro.6b00372. Epub 2016 Dec 13.

47.

Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis.

Alshikho MJ, Zürcher NR, Loggia ML, Cernasov P, Chonde DB, Izquierdo Garcia D, Yasek JE, Akeju O, Catana C, Rosen BR, Cudkowicz ME, Hooker JM, Atassi N.

Neurology. 2016 Dec 13;87(24):2554-2561. Epub 2016 Nov 11.

48.

Development of New Positron Emission Tomography Radiotracer for BET Imaging.

Wang C, Schroeder FA, Hooker JM.

ACS Chem Neurosci. 2017 Jan 18;8(1):17-21. doi: 10.1021/acschemneuro.6b00288. Epub 2016 Nov 10.

PMID:
27806195
49.

Neuroinflammatory component of gray matter pathology in multiple sclerosis.

Herranz E, Giannì C, Louapre C, Treaba CA, Govindarajan ST, Ouellette R, Loggia ML, Sloane JA, Madigan N, Izquierdo-Garcia D, Ward N, Mangeat G, Granberg T, Klawiter EC, Catana C, Hooker JM, Taylor N, Ionete C, Kinkel RP, Mainero C.

Ann Neurol. 2016 Nov;80(5):776-790. doi: 10.1002/ana.24791. Epub 2016 Oct 25.

50.

Activity-dependent Regulation of Histone Lysine Demethylase KDM1A by a Putative Thiol/Disulfide Switch.

Ricq EL, Hooker JM, Haggarty SJ.

J Biol Chem. 2016 Nov 18;291(47):24756-24767. Epub 2016 Sep 15.

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