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Items: 1 to 50 of 57

1.

Live cell analyses of synaptonemal complex dynamics and chromosome movements in cultured mouse testis tubules and embryonic ovaries.

Enguita-Marruedo A, Van Cappellen WA, Hoogerbrugge JW, Carofiglio F, Wassenaar E, Slotman JA, Houtsmuller A, Baarends WM.

Chromosoma. 2018 Sep;127(3):341-359. doi: 10.1007/s00412-018-0668-7. Epub 2018 Mar 26.

2.

Incomplete meiotic sex chromosome inactivation in the domestic dog.

Federici F, Mulugeta E, Schoenmakers S, Wassenaar E, Hoogerbrugge JW, van der Heijden GW, van Cappellen WA, Slotman JA, van IJcken WF, Laven JS, Grootegoed JA, Baarends WM.

BMC Genomics. 2015 Apr 12;16:291. doi: 10.1186/s12864-015-1501-9.

3.

Evolution of testis-specific kinases TSSK1B and TSSK2 in primates.

Shang P, Hoogerbrugge J, Baarends WM, Grootegoed JA.

Andrology. 2013 Jan;1(1):160-8. doi: 10.1111/j.2047-2927.2012.00021.x. Epub 2012 Oct 23.

4.

The ubiquitin-conjugating enzyme HR6B is required for maintenance of X chromosome silencing in mouse spermatocytes and spermatids.

Mulugeta Achame E, Wassenaar E, Hoogerbrugge JW, Sleddens-Linkels E, Ooms M, Sun ZW, van IJcken WF, Grootegoed JA, Baarends WM.

BMC Genomics. 2010 Jun 10;11:367. doi: 10.1186/1471-2164-11-367.

5.

Functional transformation of the chromatoid body in mouse spermatids requires testis-specific serine/threonine kinases.

Shang P, Baarends WM, Hoogerbrugge J, Ooms MP, van Cappellen WA, de Jong AA, Dohle GR, van Eenennaam H, Gossen JA, Grootegoed JA.

J Cell Sci. 2010 Feb 1;123(Pt 3):331-9. doi: 10.1242/jcs.059949. Epub 2010 Jan 5.

6.

Functional analysis of novel androgen receptor mutations in a unique cohort of Indonesian patients with a disorder of sex development.

Elfferich P, Juniarto AZ, Dubbink HJ, van Royen ME, Molier M, Hoogerbrugge J, Houtsmuller AB, Trapman J, Santosa A, de Jong FH, Drop SL, Faradz SM, Bruggenwirth H, Brinkmann AO.

Sex Dev. 2009;3(5):237-44. doi: 10.1159/000252814. Epub 2009 Oct 23.

PMID:
19851057
7.

Female meiotic sex chromosome inactivation in chicken.

Schoenmakers S, Wassenaar E, Hoogerbrugge JW, Laven JS, Grootegoed JA, Baarends WM.

PLoS Genet. 2009 May;5(5):e1000466. doi: 10.1371/journal.pgen.1000466. Epub 2009 May 22.

8.

The probability to initiate X chromosome inactivation is determined by the X to autosomal ratio and X chromosome specific allelic properties.

Monkhorst K, de Hoon B, Jonkers I, Mulugeta Achame E, Monkhorst W, Hoogerbrugge J, Rentmeester E, Westerhoff HV, Grosveld F, Grootegoed JA, Gribnau J.

PLoS One. 2009;4(5):e5616. doi: 10.1371/journal.pone.0005616. Epub 2009 May 19.

9.

A novel mutation F826L in the human androgen receptor in partial androgen insensitivity syndrome; increased NH2-/COOH-terminal domain interaction and TIF2 co-activation.

Wong HY, Hoogerbrugge JW, Pang KL, van Leeuwen M, van Royen ME, Molier M, Berrevoets CA, Dooijes D, Dubbink HJ, van de Wijngaart DJ, Wolffenbuttel KP, Trapman J, Kleijer WJ, Drop SL, Grootegoed JA, Brinkmann AO.

Mol Cell Endocrinol. 2008 Sep 24;292(1-2):69-78. doi: 10.1016/j.mce.2008.06.016. Epub 2008 Jul 5.

PMID:
18656523
10.

Increased phosphorylation and dimethylation of XY body histones in the Hr6b-knockout mouse is associated with derepression of the X chromosome.

Baarends WM, Wassenaar E, Hoogerbrugge JW, Schoenmakers S, Sun ZW, Grootegoed JA.

J Cell Sci. 2007 Jun 1;120(Pt 11):1841-51. Epub 2007 May 8.

11.

The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis.

Akhmanova A, Mausset-Bonnefont AL, van Cappellen W, Keijzer N, Hoogenraad CC, Stepanova T, Drabek K, van der Wees J, Mommaas M, Onderwater J, van der Meulen H, Tanenbaum ME, Medema RH, Hoogerbrugge J, Vreeburg J, Uringa EJ, Grootegoed JA, Grosveld F, Galjart N.

Genes Dev. 2005 Oct 15;19(20):2501-15.

12.

Hedgehog signaling in mouse ovary: Indian hedgehog and desert hedgehog from granulosa cells induce target gene expression in developing theca cells.

Wijgerde M, Ooms M, Hoogerbrugge JW, Grootegoed JA.

Endocrinology. 2005 Aug;146(8):3558-66. Epub 2005 May 5.

PMID:
15878962
13.

Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis.

Baarends WM, Wassenaar E, van der Laan R, Hoogerbrugge J, Sleddens-Linkels E, Hoeijmakers JH, de Boer P, Grootegoed JA.

Mol Cell Biol. 2005 Feb;25(3):1041-53.

14.

Basic helix-loop-helix transcription factor Tcfl5 interacts with the Calmegin gene promoter in mouse spermatogenesis.

Siep M, Sleddens-Linkels E, Mulders S, van Eenennaam H, Wassenaar E, Van Cappellen WA, Hoogerbrugge J, Grootegoed JA, Baarends WM.

Nucleic Acids Res. 2004 Dec 7;32(21):6425-36. Print 2004.

15.

Ubiquitin ligase Rad18Sc localizes to the XY body and to other chromosomal regions that are unpaired and transcriptionally silenced during male meiotic prophase.

van der Laan R, Uringa EJ, Wassenaar E, Hoogerbrugge JW, Sleddens E, Odijk H, Roest HP, de Boer P, Hoeijmakers JH, Grootegoed JA, Baarends WM.

J Cell Sci. 2004 Oct 1;117(Pt 21):5023-33. Epub 2004 Sep 21.

16.

The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.

Roest HP, Baarends WM, de Wit J, van Klaveren JW, Wassenaar E, Hoogerbrugge JW, van Cappellen WA, Hoeijmakers JH, Grootegoed JA.

Mol Cell Biol. 2004 Jun;24(12):5485-95.

17.

Rat testicular germ cells and Sertoli cells release different types of bioactive transforming growth factor beta in vitro.

Haagmans BL, Hoogerbrugge JW, Themmen AP, Teerds KJ.

Reprod Biol Endocrinol. 2003 Feb 5;1:3.

18.

Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.

Baarends WM, Wassenaar E, Hoogerbrugge JW, van Cappellen G, Roest HP, Vreeburg J, Ooms M, Hoeijmakers JH, Grootegoed JA.

Mol Cell Biol. 2003 Feb;23(4):1151-62.

19.

Characterization of mRAD18Sc, a mouse homolog of the yeast postreplication repair gene RAD18.

van der Laan R, Roest HP, Hoogerbrugge JW, Smit EM, Slater R, Baarends WM, Hoeijmakers JH, Grootegoed JA.

Genomics. 2000 Oct 1;69(1):86-94.

PMID:
11013078
20.

Follicle-stimulating hormone and testosterone stimulation of immature and mature Sertoli cells in vitro: inhibin and N-cadherin levels and round spermatid binding.

Lampa J, Hoogerbrugge JW, Baarends WM, Stanton PG, Perryman KJ, Grootegoed JA, Robertson DM.

J Androl. 1999 May-Jun;20(3):399-406.

21.

Histone ubiquitination and chromatin remodeling in mouse spermatogenesis.

Baarends WM, Hoogerbrugge JW, Roest HP, Ooms M, Vreeburg J, Hoeijmakers JH, Grootegoed JA.

Dev Biol. 1999 Mar 15;207(2):322-33.

22.

Differential expression pattern of retinoid X receptors in adult murine testicular cells implies varying roles for these receptors in spermatogenesis.

Gaemers IC, van Pelt AM, van der Saag PT, Hoogerbrugge JW, Themmen AP, de Rooij DG.

Biol Reprod. 1998 Jun;58(6):1351-6.

PMID:
9623592
23.

Testis-specific expression of a functional retroposon encoding glucose-6-phosphate dehydrogenase in the mouse.

Hendriksen PJ, Hoogerbrugge JW, Baarends WM, de Boer P, Vreeburg JT, Vos EA, van der Lende T, Grootegoed JA.

Genomics. 1997 May 1;41(3):350-9.

PMID:
9169132
24.
25.

Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification.

Roest HP, van Klaveren J, de Wit J, van Gurp CG, Koken MH, Vermey M, van Roijen JH, Hoogerbrugge JW, Vreeburg JT, Baarends WM, Bootsma D, Grootegoed JA, Hoeijmakers JH.

Cell. 1996 Sep 6;86(5):799-810.

26.

Expression of the ubiquitin-conjugating DNA repair enzymes HHR6A and B suggests a role in spermatogenesis and chromatin modification.

Koken MH, Hoogerbrugge JW, Jasper-Dekker I, de Wit J, Willemsen R, Roest HP, Grootegoed JA, Hoeijmakers JH.

Dev Biol. 1996 Jan 10;173(1):119-32.

27.

Anti-müllerian hormone and anti-müllerian hormone type II receptor messenger ribonucleic acid expression during postnatal testis development and in the adult testis of the rat.

Baarends WM, Hoogerbrugge JW, Post M, Visser JA, De Rooij DG, Parvinen M, Themmen AP, Grootegoed JA.

Endocrinology. 1995 Dec;136(12):5614-22.

PMID:
7588316
28.

Anti-müllerian hormone and anti-müllerian hormone type II receptor messenger ribonucleic acid expression in rat ovaries during postnatal development, the estrous cycle, and gonadotropin-induced follicle growth.

Baarends WM, Uilenbroek JT, Kramer P, Hoogerbrugge JW, van Leeuwen EC, Themmen AP, Grootegoed JA.

Endocrinology. 1995 Nov;136(11):4951-62.

PMID:
7588229
29.

Molecular and cellular events in spermatogenesis.

Grootegoed JA, Baarends WM, Hendriksen PJ, Hoogerbrugge JW, Slegtenhorst-Eegdeman KE, Themmen AP.

Hum Reprod. 1995 Oct;10 Suppl 1:10-4. Review. No abstract available.

PMID:
8592024
30.

Postmeiotic transcription of X and Y chromosomal genes during spermatogenesis in the mouse.

Hendriksen PJ, Hoogerbrugge JW, Themmen AP, Koken MH, Hoeijmakers JH, Oostra BA, van der Lende T, Grootegoed JA.

Dev Biol. 1995 Aug;170(2):730-3.

31.

A novel member of the transmembrane serine/threonine kinase receptor family is specifically expressed in the gonads and in mesenchymal cells adjacent to the müllerian duct.

Baarends WM, van Helmond MJ, Post M, van der Schoot PJ, Hoogerbrugge JW, de Winter JP, Uilenbroek JT, Karels B, Wilming LG, Meijers JH, et al.

Development. 1994 Jan;120(1):189-97.

32.

Induction and repair of DNA single-strand breaks and DNA base damage at different cellular stages of spermatogenesis of the hamster upon in vitro exposure to ionizing radiation.

van Loon AA, Sonneveld E, Hoogerbrugge J, van der Schans GP, Grootegoed JA, Lohman PH, Baan RA.

Mutat Res. 1993 Aug;294(2):139-48.

PMID:
7687006
33.

Transcriptional regulation of androgen receptor gene expression in Sertoli cells and other cell types.

Blok LJ, Themmen AP, Peters AH, Trapman J, Baarends WM, Hoogerbrugge JW, Grootegoed JA.

Mol Cell Endocrinol. 1992 Oct;88(1-3):153-64.

PMID:
1334008
35.

Activin receptor mRNA expression in rat testicular cell types.

de Winter JP, Themmen AP, Hoogerbrugge JW, Klaij IA, Grootegoed JA, de Jong FH.

Mol Cell Endocrinol. 1992 Jan;83(1):R1-8.

PMID:
1312957
36.

The stimulatory effect of albumin on luteinizing hormone-stimulated Leydig cell steroid production depends on its fatty acid content and correlates with conformational changes.

Melsert R, Bos OJ, van der Linden RF, Fischer MJ, Wilting J, Janssen LH, Hoogerbrugge JW, Rommerts FF.

Mol Cell Endocrinol. 1991 Nov;82(1):23-32.

PMID:
1662164
37.

Follitropin receptor down-regulation involves a cAMP-dependent post-transcriptional decrease of receptor mRNA expression.

Themmen AP, Blok LJ, Post M, Baarends WM, Hoogerbrugge JW, Parmentier M, Vassart G, Grootegoed JA.

Mol Cell Endocrinol. 1991 Jul;78(3):R7-13.

PMID:
1723386
38.

Short-term stimulatory effect of Sertoli cell conditioned medium on Leydig cell steroidogenesis is not mediated by inhibin.

Grootenhuis AJ, Melsert R, Timmerman MA, Hoogerbrugge JW, Rommerts FF, de Jong FH.

J Steroid Biochem. 1990 Aug 14;36(5):445-9.

PMID:
2120516
39.

Albumin, a biologically active protein acting on Leydig cells.

Melsert R, Hoogerbrugge JW, Rommerts FF.

Mol Cell Endocrinol. 1989 Jun;64(1):35-44.

PMID:
2759339
40.

The albumin fraction of rat testicular fluid stimulates steroid production by isolated Leydig cells.

Melsert R, Hoogerbrugge JW, Rommerts FF.

Mol Cell Endocrinol. 1988 Oct;59(3):221-31.

PMID:
3181622
42.

The possible role of protein kinase C and phospholipids in the regulation of steroid production in rat Leydig cells.

Themmen AP, Hoogerbrugge JW, Rommerts FF, van der Molen HJ.

FEBS Lett. 1986 Jul 28;203(2):116-20.

43.
44.
45.

Ethane dimethane sulphonate (EDS) specifically inhibits LH stimulated steroidogenesis in Leydig cells isolated from mature rats but not in cells from immature rats.

Rommerts FF, Grootenhuis AJ, Hoogerbrugge JW, van der Molen HJ.

Mol Cell Endocrinol. 1985 Sep;42(2):105-11.

PMID:
2998903
46.

Is cAMP the obligatory second messenger in the action of lutropin on Leydig cell steroidogenesis.

Themmen AP, Hoogerbrugge JW, Rommerts FF, van der Molen HJ.

Biochem Biophys Res Commun. 1985 May 16;128(3):1164-72.

PMID:
2988530
47.

Lutropin stimulates de novo synthesis of short-lived proteins required for lutropin-dependent steroid production in tumour Leydig cells.

Bakker GH, Hoogerbrugge JW, Rommerts FF, van der Molen HJ.

J Steroid Biochem. 1985 Mar;22(3):311-4.

PMID:
2581067
48.

Side-chain cleavage of C27-3-oxo-4-ene sterols.

Degenhart HJ, Alsema GJ, Hoogerbrugge J, Wolthers BG, Kaptein R.

J Steroid Biochem. 1984 Oct;21(4):447-51.

PMID:
6492802
49.

Development of adenosine responsiveness after isolation of Leydig cells.

Rommerts FF, Molenaar R, Hoogerbrugge JW, van der Molen HJ.

Biol Reprod. 1984 May;30(4):842-7.

PMID:
6329334
50.

Development of adenosine responsiveness after isolation of Leydig cells.

Rommerts FF, Molenaar R, Hoogerbrugge JW, van der Molen HJ.

Ann N Y Acad Sci. 1984;438:609-11. No abstract available.

PMID:
6100026

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