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Items: 39


The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.

Pang SS, Bayly-Jones C, Radjainia M, Spicer BA, Law RHP, Hodel AW, Parsons ES, Ekkel SM, Conroy PJ, Ramm G, Venugopal H, Bird PI, Hoogenboom BW, Voskoboinik I, Gambin Y, Sierecki E, Dunstone MA, Whisstock JC.

Nat Commun. 2019 Sep 19;10(1):4288. doi: 10.1038/s41467-019-12279-2.


Quantification of Biomolecular Dynamics Inside Real and Synthetic Nuclear Pore Complexes Using Time-Resolved Atomic Force Microscopy.

Stanley GJ, Akpinar B, Shen Q, Fisher PDE, Lusk CP, Lin C, Hoogenboom BW.

ACS Nano. 2019 Jul 23;13(7):7949-7956. doi: 10.1021/acsnano.9b02424. Epub 2019 Jul 1.


Helminth Defense Molecules as Design Templates for Membrane Active Antibiotics.

Hammond K, Lewis H, Faruqui N, Russell C, Hoogenboom BW, Ryadnov MG.

ACS Infect Dis. 2019 Aug 9;5(8):1471-1479. doi: 10.1021/acsinfecdis.9b00157. Epub 2019 May 30.


Single-molecule kinetics of pore assembly by the membrane attack complex.

Parsons ES, Stanley GJ, Pyne ALB, Hodel AW, Nievergelt AP, Menny A, Yon AR, Rowley A, Richter RP, Fantner GE, Bubeck D, Hoogenboom BW.

Nat Commun. 2019 May 6;10(1):2066. doi: 10.1038/s41467-019-10058-7.


Bacterial killing by complement requires membrane attack complex formation via surface-bound C5 convertases.

Heesterbeek DA, Bardoel BW, Parsons ES, Bennett I, Ruyken M, Doorduijn DJ, Gorham RD Jr, Berends ET, Pyne AL, Hoogenboom BW, Rooijakkers SH.

EMBO J. 2019 Feb 15;38(4). pii: e99852. doi: 10.15252/embj.201899852. Epub 2019 Jan 14.


Atomic force microscopy reveals structural variability amongst nuclear pore complexes.

Stanley GJ, Fassati A, Hoogenboom BW.

Life Sci Alliance. 2018 Aug 20;1(4):e201800142. doi: 10.26508/lsa.201800142. eCollection 2018 Aug.


Author Correction: Tuneable poration: host defense peptides as sequence probes for antimicrobial mechanisms.

Pfeil MP, Pyne ALB, Losasso V, Ravi J, Lamarre B, Faruqui N, Alkassem H, Hammond K, Judge PJ, Winn M, Martyna GJ, Crain J, Watts A, Hoogenboom BW, Ryadnov MG.

Sci Rep. 2018 Nov 19;8(1):17266. doi: 10.1038/s41598-018-35521-1.


Tuneable poration: host defense peptides as sequence probes for antimicrobial mechanisms.

Pfeil MP, Pyne ALB, Losasso V, Ravi J, Lamarre B, Faruqui N, Alkassem H, Hammond K, Judge PJ, Winn M, Martyna GJ, Crain J, Watts A, Hoogenboom BW, Ryadnov MG.

Sci Rep. 2018 Oct 8;8(1):14926. doi: 10.1038/s41598-018-33289-y. Erratum in: Sci Rep. 2018 Nov 19;8(1):17266.


The case for biophysics super-groups in physics departments.

Hoogenboom BW, Leake MC.

Phys Biol. 2018 Jul 6;15(6):060201. doi: 10.1088/1478-3975/aaca0a.


A Programmable DNA Origami Platform for Organizing Intrinsically Disordered Nucleoporins within Nanopore Confinement.

Fisher PDE, Shen Q, Akpinar B, Davis LK, Chung KKH, Baddeley D, Šarić A, Melia TJ, Hoogenboom BW, Lin C, Lusk CP.

ACS Nano. 2018 Feb 27;12(2):1508-1518. doi: 10.1021/acsnano.7b08044. Epub 2018 Jan 25.


Antimicrobial peptide capsids of de novo design.

De Santis E, Alkassem H, Lamarre B, Faruqui N, Bella A, Noble JE, Micale N, Ray S, Burns JR, Yon AR, Hoogenboom BW, Ryadnov MG.

Nat Commun. 2017 Dec 22;8(1):2263. doi: 10.1038/s41467-017-02475-3.


Biomechanics of the transport barrier in the nuclear pore complex.

Stanley GJ, Fassati A, Hoogenboom BW.

Semin Cell Dev Biol. 2017 Aug;68:42-51. doi: 10.1016/j.semcdb.2017.05.007. Epub 2017 May 12. Review.


Engineering monolayer poration for rapid exfoliation of microbial membranes.

Pyne A, Pfeil MP, Bennett I, Ravi J, Iavicoli P, Lamarre B, Roethke A, Ray S, Jiang H, Bella A, Reisinger B, Yin D, Little B, Muñoz-García JC, Cerasoli E, Judge PJ, Faruqui N, Calzolai L, Henrion A, Martyna GJ, Grovenor CRM, Crain J, Hoogenboom BW, Watts A, Ryadnov MG.

Chem Sci. 2017 Feb 1;8(2):1105-1115. doi: 10.1039/c6sc02925f. Epub 2016 Sep 26.


Real-time visualization of perforin nanopore assembly.

Leung C, Hodel AW, Brennan AJ, Lukoyanova N, Tran S, House CM, Kondos SC, Whisstock JC, Dunstone MA, Trapani JA, Voskoboinik I, Saibil HR, Hoogenboom BW.

Nat Nanotechnol. 2017 May;12(5):467-473. doi: 10.1038/nnano.2016.303. Epub 2017 Feb 6.


Studies of G-quadruplexes formed within self-assembled DNA mini-circles.

Klejevskaja B, Pyne AL, Reynolds M, Shivalingam A, Thorogate R, Hoogenboom BW, Ying L, Vilar R.

Chem Commun (Camb). 2016 Oct 13;52(84):12454-12457.


Imaging DNA Structure by Atomic Force Microscopy.

Pyne AL, Hoogenboom BW.

Methods Mol Biol. 2016;1431:47-60. doi: 10.1007/978-1-4939-3631-1_5.


The membrane attack complex, perforin and cholesterol-dependent cytolysin superfamily of pore-forming proteins.

Lukoyanova N, Hoogenboom BW, Saibil HR.

J Cell Sci. 2016 Jun 1;129(11):2125-33. doi: 10.1242/jcs.182741. Epub 2016 May 13. Review.


Atomic force microscopy of membrane pore formation by cholesterol dependent cytolysins.

Hodel AW, Leung C, Dudkina NV, Saibil HR, Hoogenboom BW.

Curr Opin Struct Biol. 2016 Aug;39:8-15. doi: 10.1016/ Epub 2016 Apr 7. Review. No abstract available.


A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies.

Zahn R, Osmanović D, Ehret S, Araya Callis C, Frey S, Stewart M, You C, Görlich D, Hoogenboom BW, Richter RP.

Elife. 2016 Apr 8;5. pii: e14119. doi: 10.7554/eLife.14119.


Structurally plastic peptide capsules for synthetic antimicrobial viruses.

Castelletto V, de Santis E, Alkassem H, Lamarre B, Noble JE, Ray S, Bella A, Burns JR, Hoogenboom BW, Ryadnov MG.

Chem Sci. 2016 Mar 1;7(3):1707-1711. doi: 10.1039/c5sc03260a. Epub 2015 Dec 21.


Reversible Dissolution of Microdomains in Detergent-Resistant Membranes at Physiological Temperature.

Cremona A, Orsini F, Corsetto PA, Hoogenboom BW, Rizzo AM.

PLoS One. 2015 Jul 6;10(7):e0132696. doi: 10.1371/journal.pone.0132696. eCollection 2015.


Effects of rotational symmetry breaking in polymer-coated nanopores.

Osmanović D, Kerr-Winter M, Eccleston RC, Hoogenboom BW, Ford IJ.

J Chem Phys. 2015 Jan 21;142(3):034901. doi: 10.1063/1.4905719.


Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin.

Leung C, Dudkina NV, Lukoyanova N, Hodel AW, Farabella I, Pandurangan AP, Jahan N, Pires Damaso M, Osmanović D, Reboul CF, Dunstone MA, Andrew PW, Lonnen R, Topf M, Saibil HR, Hoogenboom BW.

Elife. 2014 Dec 2;3:e04247. doi: 10.7554/eLife.04247. Erratum in: Elife. 2014;4:e06740.


Nanoscale stiffness topography reveals structure and mechanics of the transport barrier in intact nuclear pore complexes.

Bestembayeva A, Kramer A, Labokha AA, Osmanović D, Liashkovich I, Orlova EV, Ford IJ, Charras G, Fassati A, Hoogenboom BW.

Nat Nanotechnol. 2015 Jan;10(1):60-64. doi: 10.1038/nnano.2014.262. Epub 2014 Nov 24.


Atomic force microscopy on plasma membranes from Xenopus laevis oocytes containing human aquaporin 4.

Orsini F, Santacroce M, Cremona A, Gosvami NN, Lascialfari A, Hoogenboom BW.

J Mol Recognit. 2014 Nov;27(11):669-75. doi: 10.1002/jmr.2390.


Single-molecule reconstruction of oligonucleotide secondary structure by atomic force microscopy.

Pyne A, Thompson R, Leung C, Roy D, Hoogenboom BW.

Small. 2014 Aug 27;10(16):3257-61. doi: 10.1002/smll.201400265. Epub 2014 Apr 17.


Model inspired by nuclear pore complex suggests possible roles for nuclear transport receptors in determining its structure.

Osmanović D, Ford IJ, Hoogenboom BW.

Biophys J. 2013 Dec 17;105(12):2781-9. doi: 10.1016/j.bpj.2013.11.013.


Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers.

Rakowska PD, Jiang H, Ray S, Pyne A, Lamarre B, Carr M, Judge PJ, Ravi J, Gerling UI, Koksch B, Martyna GJ, Hoogenboom BW, Watts A, Crain J, Grovenor CR, Ryadnov MG.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):8918-23. doi: 10.1073/pnas.1222824110. Epub 2013 May 13.


Bistable collective behavior of polymers tethered in a nanopore.

Osmanovic D, Bailey J, Harker AH, Fassati A, Hoogenboom BW, Ford IJ.

Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Jun;85(6 Pt 1):061917. Epub 2012 Jun 21.


Using micromechanical resonators to measure rheological properties and alcohol content of model solutions and commercial beverages.

Paxman R, Stinson J, Dejardin A, McKendry RA, Hoogenboom BW.

Sensors (Basel). 2012;12(5):6497-507. doi: 10.3390/s120506497. Epub 2012 May 16.


Atomic force microscopy with nanoscale cantilevers resolves different structural conformations of the DNA double helix.

Leung C, Bestembayeva A, Thorogate R, Stinson J, Pyne A, Marcovich C, Yang J, Drechsler U, Despont M, Jankowski T, Tschöpe M, Hoogenboom BW.

Nano Lett. 2012 Jul 11;12(7):3846-50. doi: 10.1021/nl301857p. Epub 2012 Jun 29.


Digitally tunable, wide-band amplitude, phase, and frequency detection for atomic-resolution scanning force microscopy.

Khan Z, Leung C, Tahir BA, Hoogenboom BW.

Rev Sci Instrum. 2010 Jul;81(7):073704. doi: 10.1063/1.3458009.


Imaging the essential role of spin fluctuations in high-T(c) superconductivity.

Jenkins N, Fasano Y, Berthod C, Maggio-Aprile I, Piriou A, Giannini E, Hoogenboom BW, Hess C, Cren T, Fischer Ø.

Phys Rev Lett. 2009 Nov 27;103(22):227001. Epub 2009 Nov 23.


Imaging surface charges of individual biomolecules.

Leung C, Kinns H, Hoogenboom BW, Howorka S, Mesquida P.

Nano Lett. 2009 Jul;9(7):2769-73. doi: 10.1021/nl9012979.


Potential of interferometric cantilever detection and its application for SFM/AFM in liquids.

Hoogenboom BW, Frederix PL, Fotiadis D, Hug HJ, Engel A.

Nanotechnology. 2008 Sep 24;19(38):384019. doi: 10.1088/0957-4484/19/38/384019. Epub 2008 Aug 12.


The supramolecular assemblies of voltage-dependent anion channels in the native membrane.

Hoogenboom BW, Suda K, Engel A, Fotiadis D.

J Mol Biol. 2007 Jul 6;370(2):246-55. Epub 2007 May 10.


Field dependent coherence length in the superclean, high-kappa superconductor CeCoIn5.

DeBeer-Schmitt L, Dewhurst CD, Hoogenboom BW, Petrovic C, Eskildsen MR.

Phys Rev Lett. 2006 Sep 22;97(12):127001. Epub 2006 Sep 21.


Hexagonal and square flux line lattices in CeCoIn5.

Eskildsen MR, Dewhurst CD, Hoogenboom BW, Petrovic C, Canfield PC.

Phys Rev Lett. 2003 May 9;90(18):187001. Epub 2003 May 7.


Linear and field-independent relation between vortex core state energy and gap in Bi(2)Sr(2)CaCu(2)O(8+delta).

Hoogenboom BW, Kadowaki K, Revaz B, Li M, Renner C, Fischer Ø.

Phys Rev Lett. 2001 Dec 24;87(26):267001. Epub 2001 Dec 4.


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