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Jupiter microtubule-associated homolog 1 (JPT1): A predictive and pharmacodynamic biomarker of metformin response in endometrial cancers.

Bateman NW, Teng PN, Hope E, Hood BL, Oliver J, Ao W, Zhou M, Wang G, Tommarello D, Wilson K, Litzy T, Conrads KA, Hamilton CA, Darcy KM, Casablanca Y, Maxwell GL, Bae-Jump V, Conrads TP.

Cancer Med. 2019 Dec 6. doi: 10.1002/cam4.2729. [Epub ahead of print]


Biomarker panel for early detection of endometrial cancer in the Prostate, Lung, Colorectal, and Ovarian cancer screening trial.

Tarney CM, Wang G, Bateman NW, Conrads KA, Zhou M, Hood BL, Loffredo J, Tian C, Darcy KM, Hamilton CA, Casablanca Y, Lokshin A, Conrads TP, Maxwell GL.

Am J Obstet Gynecol. 2019 Nov;221(5):472.e1-472.e10. doi: 10.1016/j.ajog.2019.06.005. Epub 2019 Jul 4.


Increased Cholesterol Biosynthesis Is a Key Characteristic of Breast Cancer Stem Cells Influencing Patient Outcome.

Ehmsen S, Pedersen MH, Wang G, Terp MG, Arslanagic A, Hood BL, Conrads TP, Leth-Larsen R, Ditzel HJ.

Cell Rep. 2019 Jun 25;27(13):3927-3938.e6. doi: 10.1016/j.celrep.2019.05.104.


Bidirectional modulation of HIF-2 activity through chemical ligands.

Wu D, Su X, Lu J, Li S, Hood BL, Vasile S, Potluri N, Diao X, Kim Y, Khorasanizadeh S, Rastinejad F.

Nat Chem Biol. 2019 Apr;15(4):367-376. doi: 10.1038/s41589-019-0234-5. Epub 2019 Feb 25.


A Pharmacochaperone-Based High-Throughput Screening Assay for the Discovery of Chemical Probes of Orphan Receptors.

Morfa CJ, Bassoni D, Szabo A, McAnally D, Sharir H, Hood BL, Vasile S, Wehrman T, Lamerdin J, Smith LH.

Assay Drug Dev Technol. 2018 Oct;16(7):384-396. doi: 10.1089/adt.2018.868. Epub 2018 Sep 22.


CYPOR is a novel and independent prognostic biomarker of recurrence-free survival in triple-negative breast cancer patients.

Pedersen MH, Hood BL, Ehmsen S, Beck HC, Conrads TP, Bak M, Ditzel HJ, Leth-Larsen R.

Int J Cancer. 2019 Feb 1;144(3):631-640. doi: 10.1002/ijc.31798. Epub 2018 Nov 7.


Therapeutic and prognostic significance of PARP-1 in advanced mycosis fungoides and Sezary syndrome.

Lemchak D, Banerjee S, Digambar SS, Hood BL, Conrads TP, Jedrych J, Geskin L, Akilov OE.

Exp Dermatol. 2018 Feb;27(2):188-190. doi: 10.1111/exd.13477. Epub 2017 Dec 21.


Race-specific molecular alterations correlate with differential outcomes for black and white endometrioid endometrial cancer patients.

Bateman NW, Dubil EA, Wang G, Hood BL, Oliver JM, Litzi TA, Gist GD, Mitchell DA, Blanton B, Phippen NT, Tian C, Zahn CM, Cohn DE, Havrilesky LJ, Berchuck A, Shriver CD, Darcy KM, Hamilton CA, Conrads TP, Maxwell GL.

Cancer. 2017 Oct 15;123(20):4004-4012. doi: 10.1002/cncr.30813. Epub 2017 Jun 27.


Downregulation of antigen presentation-associated pathway proteins is linked to poor outcome in triple-negative breast cancer patient tumors.

Pedersen MH, Hood BL, Beck HC, Conrads TP, Ditzel HJ, Leth-Larsen R.

Oncoimmunology. 2017 Mar 16;6(5):e1305531. doi: 10.1080/2162402X.2017.1305531. eCollection 2017.


Quantitative Mass Spectrometry by Isotope Dilution and Multiple Reaction Monitoring (MRM).

Russo P, Hood BL, Bateman NW, Conrads TP.

Methods Mol Biol. 2017;1606:313-332. doi: 10.1007/978-1-4939-6990-6_20.


Establishment and characterization of a platinum- and paclitaxel-resistant high grade serous ovarian carcinoma cell line.

Teng PN, Bateman NW, Wang G, Litzi T, Blanton BE, Hood BL, Conrads KA, Ao W, Oliver KE, Darcy KM, McGuire WP, Paz K, Sidransky D, Hamilton CA, Maxwell GL, Conrads TP.

Hum Cell. 2017 Jul;30(3):226-236. doi: 10.1007/s13577-017-0162-1. Epub 2017 Mar 1.


Human DNA polymerase ε is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19.

Moiseeva TN, Gamper AM, Hood BL, Conrads TP, Bakkenist CJ.

DNA Repair (Amst). 2016 Jul;43:9-17. doi: 10.1016/j.dnarep.2016.04.007. Epub 2016 May 7.


Label-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis.

Collins MA, An J, Hood BL, Conrads TP, Bowser RP.

J Proteome Res. 2015 Nov 6;14(11):4486-501. doi: 10.1021/acs.jproteome.5b00804. Epub 2015 Oct 8.


BRCA1 deficiency in ovarian cancer is associated with alteration in expression of several key regulators of cell motility - A proteomics study.

Gau DM, Lesnock JL, Hood BL, Bhargava R, Sun M, Darcy K, Luthra S, Chandran U, Conrads TP, Edwards RP, Kelley JL, Krivak TC, Roy P.

Cell Cycle. 2015;14(12):1884-92. doi: 10.1080/15384101.2015.1036203.


Elevated AKAP12 in paclitaxel-resistant serous ovarian cancer cells is prognostic and predictive of poor survival in patients.

Bateman NW, Jaworski E, Ao W, Wang G, Litzi T, Dubil E, Marcus C, Conrads KA, Teng PN, Hood BL, Phippen NT, Vasicek LA, McGuire WP, Paz K, Sidransky D, Hamilton CA, Maxwell GL, Darcy KM, Conrads TP.

J Proteome Res. 2015 Apr 3;14(4):1900-10. doi: 10.1021/pr5012894. Epub 2015 Mar 19.


Proteomics of the human endometrial glandular epithelium and stroma from the proliferative and secretory phases of the menstrual cycle.

Hood BL, Liu B, Alkhas A, Shoji Y, Challa R, Wang G, Ferguson S, Oliver J, Mitchell D, Bateman NW, Zahn CM, Hamilton CA, Payson M, Lessey B, Fazleabas AT, Maxwell GL, Conrads TP, Risinger JI.

Biol Reprod. 2015 Apr;92(4):106. doi: 10.1095/biolreprod.114.127217. Epub 2015 Feb 18.


The assembly of miRNA-mRNA-protein regulatory networks using high-throughput expression data.

Chu T, Mouillet JF, Hood BL, Conrads TP, Sadovsky Y.

Bioinformatics. 2015 Jun 1;31(11):1780-7. doi: 10.1093/bioinformatics/btv038. Epub 2015 Jan 24.


Evaluation of a 4-protein serum biomarker panel-biglycan, annexin-A6, myeloperoxidase, and protein S100-A9 (B-AMP)-for the detection of esophageal adenocarcinoma.

Zaidi AH, Gopalakrishnan V, Kasi PM, Zeng X, Malhotra U, Balasubramanian J, Visweswaran S, Sun M, Flint MS, Davison JM, Hood BL, Conrads TP, Bergman JJ, Bigbee WL, Jobe BA.

Cancer. 2014 Dec 15;120(24):3902-13. doi: 10.1002/cncr.28963. Epub 2014 Aug 5.


Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD.

Chattopadhyay A, Hood BL, Conrads TP, Redner RL.

Mol Cancer Res. 2014 Sep;12(9):1283-91. doi: 10.1158/1541-7786.MCR-14-0080. Epub 2014 Jul 17.


Erlotinib, erlotinib-sulindac versus placebo: a randomized, double-blind, placebo-controlled window trial in operable head and neck cancer.

Gross ND, Bauman JE, Gooding WE, Denq W, Thomas SM, Wang L, Chiosea S, Hood BL, Flint MS, Sun M, Conrads TP, Ferris RL, Johnson JT, Kim S, Argiris A, Wirth L, Nikiforova MN, Siegfried JM, Grandis JR.

Clin Cancer Res. 2014 Jun 15;20(12):3289-98. doi: 10.1158/1078-0432.CCR-13-3360. Epub 2014 Apr 11.


Choline phosphate cytidylyltransferase-α is a novel antigen detected by the anti-ERCC1 antibody 8F1 with biomarker value in patients with lung and head and neck squamous cell carcinomas.

Vaezi AE, Bepler G, Bhagwat NR, Malysa A, Rubatt JM, Chen W, Hood BL, Conrads TP, Wang L, Kemp CE, Niedernhofer LJ.

Cancer. 2014 Jun 15;120(12):1898-907. doi: 10.1002/cncr.28643. Epub 2014 Apr 1.


Identification of candidate circulating cisplatin-resistant biomarkers from epithelial ovarian carcinoma cell secretomes.

Teng PN, Wang G, Hood BL, Conrads KA, Hamilton CA, Maxwell GL, Darcy KM, Conrads TP.

Br J Cancer. 2014 Jan 7;110(1):123-32. doi: 10.1038/bjc.2013.687. Epub 2013 Oct 31.


The bc:caa3 supercomplexes from the Gram positive bacterium Bacillus subtilis respiratory chain: a megacomplex organization?

Sousa PM, Videira MA, Santos FA, Hood BL, Conrads TP, Melo AM.

Arch Biochem Biophys. 2013 Sep 1;537(1):153-60. doi: 10.1016/ Epub 2013 Jul 20.


Progesterone enhances calcitriol antitumor activity by upregulating vitamin D receptor expression and promoting apoptosis in endometrial cancer cells.

Lee LR, Teng PN, Nguyen H, Hood BL, Kavandi L, Wang G, Turbov JM, Thaete LG, Hamilton CA, Maxwell GL, Rodriguez GC, Conrads TP, Syed V.

Cancer Prev Res (Phila). 2013 Jul;6(7):731-43. doi: 10.1158/1940-6207.CAPR-12-0493. Epub 2013 May 16.


An integrated understanding of the physiological response to elevated extracellular phosphate.

Camalier CE, Yi M, Yu LR, Hood BL, Conrads KA, Lee YJ, Lin Y, Garneys LM, Bouloux GF, Young MR, Veenstra TD, Stephens RM, Colburn NH, Conrads TP, Beck GR Jr.

J Cell Physiol. 2013 Jul;228(7):1536-50. doi: 10.1002/jcp.24312.


Distinct profiles of oxidative stress-related and matrix proteins in adult bone and soft tissue osteosarcoma and desmoid tumors: a proteomics study.

Rao UN, Hood BL, Jones-Laughner JM, Sun M, Conrads TP.

Hum Pathol. 2013 May;44(5):725-33. doi: 10.1016/j.humpath.2012.06.023. Epub 2012 Oct 11.


The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.

Collins M, Riascos D, Kovalik T, An J, Krupa K, Krupa K, Hood BL, Conrads TP, Renton AE, Traynor BJ, Bowser R.

Acta Neuropathol. 2012 Nov;124(5):717-32. doi: 10.1007/s00401-012-1045-x. Epub 2012 Sep 21.


Mitochondrial respiration--an important therapeutic target in melanoma.

Barbi de Moura M, Vincent G, Fayewicz SL, Bateman NW, Hood BL, Sun M, Suhan J, Duensing S, Yin Y, Sander C, Kirkwood JM, Becker D, Conrads TP, Van Houten B, Moschos SJ.

PLoS One. 2012;7(8):e40690. doi: 10.1371/journal.pone.0040690. Epub 2012 Aug 17.


Quantitative proteomics reveal ATM kinase-dependent exchange in DNA damage response complexes.

Choi S, Srivas R, Fu KY, Hood BL, Dost B, Gibson GA, Watkins SC, Van Houten B, Bandeira N, Conrads TP, Ideker T, Bakkenist CJ.

J Proteome Res. 2012 Oct 5;11(10):4983-91. doi: 10.1021/pr3005524. Epub 2012 Sep 18.


Mitochondrial proteomic analysis of cisplatin resistance in ovarian cancer.

Chappell NP, Teng PN, Hood BL, Wang G, Darcy KM, Hamilton CA, Maxwell GL, Conrads TP.

J Proteome Res. 2012 Sep 7;11(9):4605-14. doi: 10.1021/pr300403d. Epub 2012 Aug 28.


Analysis of PSPHL as a Candidate Gene Influencing the Racial Disparity in Endometrial Cancer.

Allard JE, Chandramouli GV, Stagliano K, Hood BL, Litzi T, Shoji Y, Boyd J, Berchuck A, Conrads TP, Maxwell GL, Risinger JI.

Front Oncol. 2012 Jul 4;2:65. doi: 10.3389/fonc.2012.00065. eCollection 2012.


The aerobic respiratory chain of Escherichia coli: from genes to supercomplexes.

Sousa PMF, Videira MAM, Bohn A, Hood BL, Conrads TP, Goulao LF, Melo AMP.

Microbiology. 2012 Sep;158(Pt 9):2408-2418. doi: 10.1099/mic.0.056531-0. Epub 2012 Jun 14.


CLT1 targets angiogenic endothelium through CLIC1 and fibronectin.

Knowles LM, Malik G, Hood BL, Conrads TP, Pilch J.

Angiogenesis. 2012 Mar;15(1):115-29. doi: 10.1007/s10456-011-9247-8. Epub 2011 Dec 28.


Relative quantitation of proteins in expressed prostatic secretion with a stable isotope labeled secretome standard.

Zhao T, Zeng X, Bateman NW, Sun M, Teng PN, Bigbee WL, Dhir R, Nelson JB, Conrads TP, Hood BL.

J Proteome Res. 2012 Feb 3;11(2):1089-99. doi: 10.1021/pr200829f. Epub 2011 Dec 1.


Proteomic analysis of ovarian cancer proximal fluids: validation of elevated peroxiredoxin 1 in patient peripheral circulation.

Hoskins ER, Hood BL, Sun M, Krivak TC, Edwards RP, Conrads TP.

PLoS One. 2011;6(9):e25056. doi: 10.1371/journal.pone.0025056. Epub 2011 Sep 30.


14-3-3 binding and phosphorylation of neuroglobin during hypoxia modulate six-to-five heme pocket coordination and rate of nitrite reduction to nitric oxide.

Jayaraman T, Tejero J, Chen BB, Blood AB, Frizzell S, Shapiro C, Tiso M, Hood BL, Wang X, Zhao X, Conrads TP, Mallampalli RK, Gladwin MT.

J Biol Chem. 2011 Dec 9;286(49):42679-89. doi: 10.1074/jbc.M111.271973. Epub 2011 Sep 29.


Standardization of a sample preparation and analytical workflow for proteomics of archival endometrial cancer tissue.

Alkhas A, Hood BL, Oliver K, Teng PN, Oliver J, Mitchell D, Hamilton CA, Maxwell GL, Conrads TP.

J Proteome Res. 2011 Nov 4;10(11):5264-71. doi: 10.1021/pr2007736. Epub 2011 Oct 3.


Identification of potential protein targets of isothiocyanates by proteomics.

Mi L, Hood BL, Stewart NA, Xiao Z, Govind S, Wang X, Conrads TP, Veenstra TD, Chung FL.

Chem Res Toxicol. 2011 Oct 17;24(10):1735-43. doi: 10.1021/tx2002806. Epub 2011 Aug 26.


Preformulation and stability in biological fluids of the retrocyclin RC-101, a potential anti-HIV topical microbicide.

Sassi AB, Bunge KE, Hood BL, Conrads TP, Cole AM, Gupta P, Rohan LC.

AIDS Res Ther. 2011 Jul 29;8:27. doi: 10.1186/1742-6405-8-27.


Using C. elegans to identify the protease targets of serpins in vivo.

Bhatia SR, Miedel MT, Chotoo CK, Graf NJ, Hood BL, Conrads TP, Silverman GA, Luke CJ.

Methods Enzymol. 2011;499:283-99. doi: 10.1016/B978-0-12-386471-0.00014-6.


Identifier mapping performance for integrating transcriptomics and proteomics experimental results.

Day RS, McDade KK, Chandran UR, Lisovich A, Conrads TP, Hood BL, Kolli VS, Kirchner D, Litzi T, Maxwell GL.

BMC Bioinformatics. 2011 May 27;12:213. doi: 10.1186/1471-2105-12-213.


Proteomic analysis of stage I endometrial cancer tissue: identification of proteins associated with oxidative processes and inflammation.

Maxwell GL, Hood BL, Day R, Chandran U, Kirchner D, Kolli VS, Bateman NW, Allard J, Miller C, Sun M, Flint MS, Zahn C, Oliver J, Banerjee S, Litzi T, Parwani A, Sandburg G, Rose S, Becich MJ, Berchuck A, Kohn E, Risinger JI, Conrads TP.

Gynecol Oncol. 2011 Jun 1;121(3):586-94. doi: 10.1016/j.ygyno.2011.02.031. Epub 2011 Apr 1.


Restraint stress and stress hormones significantly impact T lymphocyte migration and function through specific alterations of the actin cytoskeleton.

Flint MS, Budiu RA, Teng PN, Sun M, Stolz DB, Lang M, Hood BL, Vlad AM, Conrads TP.

Brain Behav Immun. 2011 Aug;25(6):1187-96. doi: 10.1016/j.bbi.2011.03.009. Epub 2011 Mar 21.


Lung cancer serum biomarker discovery using label-free liquid chromatography-tandem mass spectrometry.

Zeng X, Hood BL, Zhao T, Conrads TP, Sun M, Gopalakrishnan V, Grover H, Day RS, Weissfeld JL, Wilson DO, Siegfried JM, Bigbee WL.

J Thorac Oncol. 2011 Apr;6(4):725-34. doi: 10.1097/JTO.0b013e31820c312e.


Differential proteomic analysis of late-stage and recurrent breast cancer from formalin-fixed paraffin-embedded tissues.

Bateman NW, Sun M, Bhargava R, Hood BL, Darfler MM, Kovatich AJ, Hooke JA, Krizman DB, Conrads TP.

J Proteome Res. 2011 Mar 4;10(3):1323-32. doi: 10.1021/pr101073s. Epub 2011 Jan 19.


Differential proteomic analysis of renal cell carcinoma tissue interstitial fluid.

Teng PN, Hood BL, Sun M, Dhir R, Conrads TP.

J Proteome Res. 2011 Mar 4;10(3):1333-42. doi: 10.1021/pr101074p. Epub 2011 Jan 12.


Supramolecular organizations in the aerobic respiratory chain of Escherichia coli.

Sousa PM, Silva ST, Hood BL, Charro N, Carita JN, Vaz F, Penque D, Conrads TP, Melo AM.

Biochimie. 2011 Mar;93(3):418-25. doi: 10.1016/j.biochi.2010.10.014. Epub 2010 Oct 30.


Advances in proximal fluid proteomics for disease biomarker discovery.

Teng PN, Bateman NW, Hood BL, Conrads TP.

J Proteome Res. 2010 Dec 3;9(12):6091-100. doi: 10.1021/pr100904q. Epub 2010 Nov 11. Review.


Serum proteomics signature of cystic fibrosis patients: a complementary 2-DE and LC-MS/MS approach.

Charro N, Hood BL, Faria D, Pacheco P, Azevedo P, Lopes C, de Almeida AB, Couto FM, Conrads TP, Penque D.

J Proteomics. 2011 Jan 1;74(1):110-26. doi: 10.1016/j.jprot.2010.10.001. Epub 2010 Oct 13.


Lung cancer serum biomarker discovery using glycoprotein capture and liquid chromatography mass spectrometry.

Zeng X, Hood BL, Sun M, Conrads TP, Day RS, Weissfeld JL, Siegfried JM, Bigbee WL.

J Proteome Res. 2010 Dec 3;9(12):6440-9. doi: 10.1021/pr100696n. Epub 2010 Oct 28.

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