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Items: 1 to 50 of 761

1.

PPAR-Induced Fatty Acid Oxidation in T Cells Increases the Number of Tumor-Reactive CD8+ T Cells and Facilitates Anti-PD-1 Therapy.

Chowdhury PS, Chamoto K, Kumar A, Honjo T.

Cancer Immunol Res. 2018 Aug 24. doi: 10.1158/2326-6066.CIR-18-0095. [Epub ahead of print]

PMID:
30143538
2.

Dasatinib-Induced Pulmonary Arterial Hypertension Treated with Upfront Combination Therapy.

Nishimori M, Honjo T, Kaihotsu K, Sone N, Yoshikawa S, Imanishi J, Nakayama K, Emoto N, Iwahashi M.

Case Rep Cardiol. 2018 May 20;2018:3895197. doi: 10.1155/2018/3895197. eCollection 2018.

3.

An Unusual Case of Inferior Vena Cava Thrombosis in a Healthy Male Bodybuilder.

Imanishi J, Iseri M, Motoki M, Yoshikawa S, Sone N, Honjo T, Kamemura K, Kaihotsu K, Iwahashi M.

Intern Med. 2018 Sep 1;57(17):2517-2521. doi: 10.2169/internalmedicine.0377-17. Epub 2018 Apr 27.

4.

Thermal comfort along the marathon course of the 2020 Tokyo Olympics.

Honjo T, Seo Y, Yamasaki Y, Tsunematsu N, Yokoyama H, Yamato H, Mikami T.

Int J Biometeorol. 2018 Aug;62(8):1407-1419. doi: 10.1007/s00484-018-1539-x. Epub 2018 Apr 17.

PMID:
29667034
5.

The application of a high-density street-level air temperature observation network (HiSAN): Dynamic variation characteristics of urban heat island in Tainan, Taiwan.

Chen YC, Yao CK, Honjo T, Lin TP.

Sci Total Environ. 2018 Jun 1;626:555-566. doi: 10.1016/j.scitotenv.2018.01.059. Epub 2018 Feb 19.

PMID:
29353794
6.

Depletion of recombination-specific cofactors by the C-terminal mutant of the activation-induced cytidine deaminase causes the dominant negative effect on class switch recombination.

Al Ismail A, Husain A, Kobayashi M, Honjo T, Begum NA.

Int Immunol. 2017 Dec 30;29(11):525-537. doi: 10.1093/intimm/dxx061.

PMID:
29136157
7.

Combination therapy strategies for improving PD-1 blockade efficacy: a new era in cancer immunotherapy.

Chowdhury PS, Chamoto K, Honjo T.

J Intern Med. 2018 Feb;283(2):110-120. doi: 10.1111/joim.12708. Epub 2017 Nov 16. Review.

PMID:
29071761
8.

Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior.

Miyajima M, Zhang B, Sugiura Y, Sonomura K, Guerrini MM, Tsutsui Y, Maruya M, Vogelzang A, Chamoto K, Honda K, Hikida T, Ito S, Qin H, Sanuki R, Suzuki K, Furukawa T, Ishihama Y, Matsuda F, Suematsu M, Honjo T, Fagarasan S.

Nat Immunol. 2017 Dec;18(12):1342-1352. doi: 10.1038/ni.3867. Epub 2017 Oct 23.

PMID:
29058703
9.

Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes.

McDonald G, Medina CO, Pilichowska M, Kearney JF, Shinkura R, Selsing E, Wortis HH, Honjo T, Imanishi-Kari T.

Front Immunol. 2017 Sep 13;8:1094. doi: 10.3389/fimmu.2017.01094. eCollection 2017.

10.

Role of PD-1 in Immunity and Diseases.

Chamoto K, Al-Habsi M, Honjo T.

Curr Top Microbiol Immunol. 2017;410:75-97. doi: 10.1007/82_2017_67.

PMID:
28929192
11.

Acute pulmonary edema in patients with reduced left ventricular ejection fraction is associated with concentric left ventricular geometry.

Imanishi J, Kaihotsu K, Yoshikawa S, Nishimori M, Sone N, Honjo T, Iwahashi M.

Int J Cardiovasc Imaging. 2018 Feb;34(2):185-192. doi: 10.1007/s10554-017-1218-8. Epub 2017 Aug 2.

PMID:
28770454
12.

Interaction patterns and toxicities of binary and ternary pesticide mixtures to Daphnia magna estimated by an accelerated failure time model.

Qiu X, Tanoue W, Kawaguchi A, Yanagawa T, Seki M, Shimasaki Y, Honjo T, Oshima Y.

Sci Total Environ. 2017 Dec 31;607-608:367-374. doi: 10.1016/j.scitotenv.2017.07.034. Epub 2017 Jul 27.

PMID:
28697389
13.

Decomposition of Fatty Acid and Detergency Using a System Combining Horseradish Peroxidase and p-Iodophenol.

Morita M, Tani M, Honjo T.

J Oleo Sci. 2017;66(7):797-799. doi: 10.5650/jos.ess17095.

14.

Experimental demonstration of quantum digital signatures over 43 dB channel loss using differential phase shift quantum key distribution.

Collins RJ, Amiri R, Fujiwara M, Honjo T, Shimizu K, Tamaki K, Takeoka M, Sasaki M, Andersson E, Buller GS.

Sci Rep. 2017 Jun 12;7(1):3235. doi: 10.1038/s41598-017-03401-9.

15.

Cancer immunotherapies targeting the PD-1 signaling pathway.

Iwai Y, Hamanishi J, Chamoto K, Honjo T.

J Biomed Sci. 2017 Apr 4;24(1):26. doi: 10.1186/s12929-017-0329-9. Review.

16.

The novel activation-induced deoxycytidine deaminase (AID) mutants, AIDv and AIDvΔ15 are defective in SHM and CSR.

Kobayashi M, Takemoto M, Honjo T.

DNA Repair (Amst). 2017 May;53:1-3. doi: 10.1016/j.dnarep.2017.02.015. Epub 2017 Mar 6. No abstract available.

PMID:
28292632
17.

Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity.

Chamoto K, Chowdhury PS, Kumar A, Sonomura K, Matsuda F, Fagarasan S, Honjo T.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E761-E770. doi: 10.1073/pnas.1620433114. Epub 2017 Jan 17.

18.

Erratum to: Role of PD-1 in Immunity and Diseases.

Chamoto K, Al-Habsi M, Honjo T.

Curr Top Microbiol Immunol. 2017;410:E1. doi: 10.1007/978-3-319-68929-6_69. No abstract available.

PMID:
29492725
19.

2-Aminobutyric acid modulates glutathione homeostasis in the myocardium.

Irino Y, Toh R, Nagao M, Mori T, Honjo T, Shinohara M, Tsuda S, Nakajima H, Satomi-Kobayashi S, Shinke T, Tanaka H, Ishida T, Miyata O, Hirata KI.

Sci Rep. 2016 Nov 9;6:36749. doi: 10.1038/srep36749.

20.

A coherent Ising machine for 2000-node optimization problems.

Inagaki T, Haribara Y, Igarashi K, Sonobe T, Tamate S, Honjo T, Marandi A, McMahon PL, Umeki T, Enbutsu K, Tadanaga O, Takenouchi H, Aihara K, Kawarabayashi KI, Inoue K, Utsunomiya S, Takesue H.

Science. 2016 Nov 4;354(6312):603-606. Epub 2016 Oct 20.

PMID:
27811271
21.

Experimental transmission of quantum digital signatures over 90  km of installed optical fiber using a differential phase shift quantum key distribution system.

Collins RJ, Amiri R, Fujiwara M, Honjo T, Shimizu K, Tamaki K, Takeoka M, Andersson E, Buller GS, Sasaki M.

Opt Lett. 2016 Nov 1;41(21):4883-4886. doi: 10.1364/OL.41.004883.

PMID:
27805641
22.

Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model.

Zhang B, Chikuma S, Hori S, Fagarasan S, Honjo T.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8490-5. doi: 10.1073/pnas.1608873113. Epub 2016 Jul 7.

23.

Scapula behavior associates with fast sprinting in first accelerated running.

Otsuka M, Ito T, Honjo T, Isaka T.

Springerplus. 2016 May 20;5(1):682. doi: 10.1186/s40064-016-2291-5. eCollection 2016.

24.

β-Hydroxybutyrate elevation as a compensatory response against oxidative stress in cardiomyocytes.

Nagao M, Toh R, Irino Y, Mori T, Nakajima H, Hara T, Honjo T, Satomi-Kobayashi S, Shinke T, Tanaka H, Ishida T, Hirata K.

Biochem Biophys Res Commun. 2016 Jul 8;475(4):322-8. doi: 10.1016/j.bbrc.2016.05.097. Epub 2016 May 20.

PMID:
27216458
25.

Ischemic Preconditioning Enhances Muscle Endurance during Sustained Isometric Exercise.

Tanaka D, Suga T, Tanaka T, Kido K, Honjo T, Fujita S, Hamaoka T, Isaka T.

Int J Sports Med. 2016 Jul;37(8):614-8. doi: 10.1055/s-0035-1565141. Epub 2016 May 13.

PMID:
27176889
26.

Functional requirements of AID's higher order structures and their interaction with RNA-binding proteins.

Mondal S, Begum NA, Hu W, Honjo T.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1545-54. doi: 10.1073/pnas.1601678113. Epub 2016 Feb 29.

27.

Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability.

Husain A, Begum NA, Taniguchi T, Taniguchi H, Kobayashi M, Honjo T.

Nat Commun. 2016 Feb 4;7:10549. doi: 10.1038/ncomms10549.

28.

Deletion of SHATI/NAT8L decreases the N-acetylaspartate content in the brain and induces behavioral deficits, which can be ameliorated by administering N-acetylaspartate.

Toriumi K, Mamiya T, Song Z, Honjo T, Watanabe H, Tanaka J, Kondo M, Mouri A, Kim HC, Nitta A, Fukushima T, Nabeshima T.

Eur Neuropsychopharmacol. 2015 Nov;25(11):2108-17. doi: 10.1016/j.euroneuro.2015.08.003. Epub 2015 Aug 12.

PMID:
26361739
29.

Sensitive Multiplexed Quantitative Analysis of Autoantibodies to Cancer Antigens with Chemically S-Cationized Full-Length and Water-Soluble Denatured Proteins.

Futami J, Nonomura H, Kido M, Niidoi N, Fujieda N, Hosoi A, Fujita K, Mandai K, Atago Y, Kinoshita R, Honjo T, Matsushita H, Uenaka A, Nakayama E, Kakimi K.

Bioconjug Chem. 2015 Oct 21;26(10):2076-84. doi: 10.1021/acs.bioconjchem.5b00328. Epub 2015 Sep 22.

PMID:
26355635
30.

Safety and Antitumor Activity of Anti-PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer.

Hamanishi J, Mandai M, Ikeda T, Minami M, Kawaguchi A, Murayama T, Kanai M, Mori Y, Matsumoto S, Chikuma S, Matsumura N, Abiko K, Baba T, Yamaguchi K, Ueda A, Hosoe Y, Morita S, Yokode M, Shimizu A, Honjo T, Konishi I.

J Clin Oncol. 2015 Dec 1;33(34):4015-22. doi: 10.1200/JCO.2015.62.3397. Epub 2015 Sep 8.

PMID:
26351349
31.

[112th Scientific Meeting of the Japanese Society of Internal Medicine: Special Lecture: Cancer Immunotherapy by PD-1 Antibody].

Honjo T.

Nihon Naika Gakkai Zasshi. 2015 Sep;104(9):1917. Japanese. No abstract available.

PMID:
30160898
32.

Immunization with an ApoB-100 Related Peptide Vaccine Attenuates Angiotensin-II Induced Hypertension and Renal Fibrosis in Mice.

Honjo T, Chyu KY, Dimayuga PC, Lio WM, Yano J, Trinidad P, Zhao X, Zhou J, Cercek B, Shah PK.

PLoS One. 2015 Jun 29;10(6):e0131731. doi: 10.1371/journal.pone.0131731. eCollection 2015.

33.

Maxillary Advancement for Unilateral Crossbite in a Patient with Sleep Apnea Syndrome.

Hoshijima M, Honjo T, Moritani N, Iida S, Yamashiro T, Kamioka H.

Acta Med Okayama. 2015;69(3):177-82.

34.

Interdisciplinary orthodontic treatment for a patient with generalized aggressive periodontitis: Assessment of IgG antibodies to identify type of periodontitis and correct timing of treatment.

Ishihara Y, Tomikawa K, Deguchi T, Honjo T, Suzuki K, Kono T, Kuboki T, Kamioka H, Takashiba S, Yamashiro T.

Am J Orthod Dentofacial Orthop. 2015 Jun;147(6):766-80. doi: 10.1016/j.ajodo.2014.09.022.

PMID:
26038081
35.

Ischemic preconditioning accelerates muscle deoxygenation dynamics and enhances exercise endurance during the work-to-work test.

Kido K, Suga T, Tanaka D, Honjo T, Homma T, Fujita S, Hamaoka T, Isaka T.

Physiol Rep. 2015 May;3(5). pii: e12395. doi: 10.14814/phy2.12395.

36.

Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase.

Hu W, Begum NA, Mondal S, Stanlie A, Honjo T.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5791-6. doi: 10.1073/pnas.1506167112. Epub 2015 Apr 20.

37.

ApoB-100-related peptide vaccine protects against angiotensin II-induced aortic aneurysm formation and rupture.

Honjo T, Chyu KY, Dimayuga PC, Yano J, Lio WM, Trinidad P, Zhao X, Zhou J, Chen S, Cercek B, Arditi M, Shah PK.

J Am Coll Cardiol. 2015 Feb 17;65(6):546-56. doi: 10.1016/j.jacc.2014.11.054.

38.
39.

Cancer cell death induced by the intracellular self-assembly of an enzyme-responsive supramolecular gelator.

Tanaka A, Fukuoka Y, Morimoto Y, Honjo T, Koda D, Goto M, Maruyama T.

J Am Chem Soc. 2015 Jan 21;137(2):770-5. doi: 10.1021/ja510156v. Epub 2015 Jan 5.

PMID:
25521540
40.

Administration of high dose eicosapentaenoic acid enhances anti-inflammatory properties of high-density lipoprotein in Japanese patients with dyslipidemia.

Tanaka N, Ishida T, Nagao M, Mori T, Monguchi T, Sasaki M, Mori K, Kondo K, Nakajima H, Honjo T, Irino Y, Toh R, Shinohara M, Hirata K.

Atherosclerosis. 2014 Dec;237(2):577-83. doi: 10.1016/j.atherosclerosis.2014.10.011. Epub 2014 Oct 18.

PMID:
25463091
41.

Analysis of pain level in cases treated with Invisalign aligner: comparison with fixed edgewise appliance therapy.

Fujiyama K, Honjo T, Suzuki M, Matsuoka S, Deguchi T.

Prog Orthod. 2014 Nov 22;15:64. doi: 10.1186/s40510-014-0064-7.

42.

Runx/Cbfb signaling regulates postnatal development of granular convoluted tubule in the mouse submandibular gland.

Islam MN, Itoh S, Yanagita T, Sumiyoshi K, Hayano S, Kuremoto K, Kurosaka H, Honjo T, Kawanabe N, Kamioka H, Sakai T, Ishimaru N, Taniuchi I, Yamashiro T.

Dev Dyn. 2015 Mar;244(3):488-96. doi: 10.1002/dvdy.24231. Epub 2014 Dec 15.

43.

Denatured mammalian protein mixtures exhibit unusually high solubility in nucleic acid-free pure water.

Futami J, Fujiyama H, Kinoshita R, Nonomura H, Honjo T, Tada H, Matsushita H, Abe Y, Kakimi K.

PLoS One. 2014 Nov 18;9(11):e113295. doi: 10.1371/journal.pone.0113295. eCollection 2014.

44.

APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination.

Xu J, Husain A, Hu W, Honjo T, Kobayashi M.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17242-7. doi: 10.1073/pnas.1420221111. Epub 2014 Nov 17.

45.

Quantum key distribution over a 72 dB channel loss using ultralow dark count superconducting single-photon detectors.

Shibata H, Honjo T, Shimizu K.

Opt Lett. 2014 Sep 1;39(17):5078-81. doi: 10.1364/OL.39.005078.

PMID:
25166078
46.

Opinion: uracil DNA glycosylase (UNG) plays distinct and non-canonical roles in somatic hypermutation and class switch recombination.

Yousif AS, Stanlie A, Begum NA, Honjo T.

Int Immunol. 2014 Oct;26(10):575-8. doi: 10.1093/intimm/dxu071. Epub 2014 Jul 3. Review.

47.

Chromatin reader Brd4 functions in Ig class switching as a repair complex adaptor of nonhomologous end-joining.

Stanlie A, Yousif AS, Akiyama H, Honjo T, Begum NA.

Mol Cell. 2014 Jul 3;55(1):97-110. doi: 10.1016/j.molcel.2014.05.018. Epub 2014 Jun 19.

48.

Serum myeloperoxidase/paraoxonase 1 ratio as potential indicator of dysfunctional high-density lipoprotein and risk stratification in coronary artery disease.

Haraguchi Y, Toh R, Hasokawa M, Nakajima H, Honjo T, Otsui K, Mori K, Miyamoto-Sasaki M, Shinohara M, Nishimura K, Ishida T, Hirata K.

Atherosclerosis. 2014 Jun;234(2):288-94. doi: 10.1016/j.atherosclerosis.2014.03.009. Epub 2014 Mar 19.

PMID:
24704632
49.

Cholesterol lowering modulates T cell function in vivo and in vitro.

Chyu KY, Lio WM, Dimayuga PC, Zhou J, Zhao X, Yano J, Trinidad P, Honjo T, Cercek B, Shah PK.

PLoS One. 2014 Mar 19;9(3):e92095. doi: 10.1371/journal.pone.0092095. eCollection 2014.

50.

Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase.

Yousif AS, Stanlie A, Mondal S, Honjo T, Begum NA.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E1016-24. doi: 10.1073/pnas.1402391111. Epub 2014 Mar 3.

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