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Items: 26

1.

A dose-response study in animals to evaluate the anticoagulant effect of the stage 2 unfractionated heparin USP monograph change.

Honchel R, Carraway J, Gopee N, Callicott R, Chen J, Patton R, Xu Q, Zalkkar J, Laniyonu A, Krefting I, Cato M, Robie-Suh K, Rieves R.

Regul Toxicol Pharmacol. 2011 Aug;60(3):318-22. doi: 10.1016/j.yrtph.2011.04.008. Epub 2011 Apr 29.

PMID:
21549797
2.

Early alterations in heart gene expression profiles associated with doxorubicin cardiotoxicity in rats.

Thompson KL, Rosenzweig BA, Zhang J, Knapton AD, Honchel R, Lipshultz SE, Retief J, Sistare FD, Herman EH.

Cancer Chemother Pharmacol. 2010 Jul;66(2):303-14. doi: 10.1007/s00280-009-1164-9. Epub 2009 Nov 14.

PMID:
19915844
3.

Biomarkers in peripheral blood associated with vascular injury in Sprague-Dawley rats treated with the phosphodiesterase IV inhibitors SCH 351591 or SCH 534385.

Weaver JL, Snyder R, Knapton A, Herman EH, Honchel R, Miller T, Espandiari P, Smith R, Gu YZ, Goodsaid FM, Rosenblum IY, Sistare FD, Zhang J, Hanig J.

Toxicol Pathol. 2008 Oct;36(6):840-9. doi: 10.1177/0192623308322310. Epub 2008 Sep 5.

PMID:
18776166
4.

Histopathology of vascular injury in Sprague-Dawley rats treated with phosphodiesterase IV inhibitor SCH 351591 or SCH 534385.

Zhang J, Snyder RD, Herman EH, Knapton A, Honchel R, Miller T, Espandiari P, Goodsaid FM, Rosenblum IY, Hanig JP, Sistare FD, Weaver JL.

Toxicol Pathol. 2008 Oct;36(6):827-39. doi: 10.1177/0192623308322308. Epub 2008 Sep 5.

PMID:
18776163
5.

The utility of the K6/ODC transgenic mouse as an alternative short term dermal model for carcinogenicity testing of pharmaceuticals.

Miller TJ, Honchel R, Espandiari P, Knapton A, Zhang J, Sistare FD, Hanig JP.

Regul Toxicol Pharmacol. 2008 Feb;50(1):87-97. Epub 2007 Nov 4.

PMID:
18069108
6.

Mechanisms and biomarkers of cardiovascular injury induced by phosphodiesterase inhibitor III SK&F 95654 in the spontaneously hypertensive rat.

Zhang J, Herman EH, Robertson DG, Reily MD, Knapton A, Ratajczak HV, Rifai N, Honchel R, Blanchard KT, Stoll RE, Sistare FD.

Toxicol Pathol. 2006;34(2):152-63.

PMID:
16537294
7.
8.

Loss of critical palindromic transgene promoter sequence in chemically induced Tg.AC mouse skin papillomas expressing transgene-derived mRNA.

Thompson KL, Rosenzweig BA, Honchel R, Cannon RE, Blanchard KT, Stoll RE, Sistare FD.

Mol Carcinog. 2001 Dec;32(4):176-86.

PMID:
11746829
9.

Loss of palindromic symmetry in Tg.AC mice with a nonresponder phenotype.

Honchel R, Rosenzweig BA, Thompson KL, Blanchard KT, Furst SM, Stoll RE, Sistare FD.

Mol Carcinog. 2001 Feb;30(2):99-110.

PMID:
11241757
10.

Hereditary desmoid disease in a family with a germline Alu I repeat mutation of the APC gene.

Halling KC, Lazzaro CR, Honchel R, Bufill JA, Powell SM, Arndt CA, Lindor NM.

Hum Hered. 1999 Mar;49(2):97-102.

PMID:
10077730
11.

Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes.

Thibodeau SN, French AJ, Roche PC, Cunningham JM, Tester DJ, Lindor NM, Moslein G, Baker SM, Liskay RM, Burgart LJ, Honchel R, Halling KC.

Cancer Res. 1996 Nov 1;56(21):4836-40.

12.

Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer.

Moslein G, Tester DJ, Lindor NM, Honchel R, Cunningham JM, French AJ, Halling KC, Schwab M, Goretzki P, Thibodeau SN.

Hum Mol Genet. 1996 Sep;5(9):1245-52.

PMID:
8872463
13.

Tumor necrosis factor-alpha allelic frequency and chromosome 6 allelic imbalance in patients with colorectal cancer.

Honchel R, McDonnell S, Schaid DJ, Thibodeau SN.

Cancer Res. 1996 Jan 1;56(1):145-9.

14.

Microsatellite instability in keratoacanthoma.

Halling KC, Honchel R, Pittelkow MR, Thibodeau SN.

Cancer. 1995 Nov 15;76(10):1765-71.

PMID:
8625045
15.

Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1.

Lee D, Szumlanski C, Houtman J, Honchel R, Rojas K, Overhauser J, Wieben ED, Weinshilboum RM.

Drug Metab Dispos. 1995 Mar;23(3):398-405.

PMID:
7628307
16.

Mutations in the RET protooncogene in sporadic pheochromocytomas.

Lindor NM, Honchel R, Khosla S, Thibodeau SN.

J Clin Endocrinol Metab. 1995 Feb;80(2):627-9.

PMID:
7852530
17.

Genomic instability in neoplasia.

Honchel R, Halling KC, Thibodeau SN.

Semin Cell Biol. 1995 Feb;6(1):45-52. Review.

PMID:
7620121
18.

Familial medullary thyroid cancer and prominent corneal nerves: clinical and genetic analysis.

Kane LA, Tsai MS, Gharib H, Khosla S, Robertson DM, Schaid DJ, Honchel R, Thibodeau SN.

J Clin Endocrinol Metab. 1995 Jan;80(1):289-93.

PMID:
7829628
19.

Human histamine N-methyltransferase pharmacogenetics: cloning and expression of kidney cDNA.

Girard B, Otterness DM, Wood TC, Honchel R, Wieben ED, Weinshilboum RM.

Mol Pharmacol. 1994 Mar;45(3):461-8.

PMID:
8145732
20.

Microsatellite instability in Muir-Torre syndrome.

Honchel R, Halling KC, Schaid DJ, Pittelkow M, Thibodeau SN.

Cancer Res. 1994 Mar 1;54(5):1159-63.

21.

Human thiopurine methyltransferase: molecular cloning and expression of T84 colon carcinoma cell cDNA.

Honchel R, Aksoy IA, Szumlanski C, Wood TC, Otterness DM, Wieben ED, Weinshilboum RM.

Mol Pharmacol. 1993 Jun;43(6):878-87.

PMID:
8316220
22.

Tumor necrosis factor in alcohol enhanced endotoxin liver injury.

Honchel R, Ray MB, Marsano L, Cohen D, Lee E, Shedlofsky S, McClain CJ.

Alcohol Clin Exp Res. 1992 Aug;16(4):665-9.

PMID:
1530127
23.

Human liver thiopurine methyltransferase pharmacogenetics: biochemical properties, liver-erythrocyte correlation and presence of isozymes.

Szumlanski CL, Honchel R, Scott MC, Weinshilboum RM.

Pharmacogenetics. 1992 Aug;2(4):148-59.

PMID:
1306116
24.

3,3',4,4'-Tetrabromobiphenyl sensitizes rats to the hepatotoxic effects of endotoxin by a mechanism that involves more than tumor necrosis factor.

Shedlofsky SI, Hoglen NC, Rodman LE, Honchel R, Robinson FR, Swim AT, McClain CJ, Robertson LW.

Hepatology. 1991 Dec;14(6):1201-8.

PMID:
1660020
25.

Lead enhances lipopolysaccharide and tumor necrosis factor liver injury.

Honchel R, Marsano L, Cohen D, Shedlofsky S, McClain CJ.

J Lab Clin Med. 1991 Mar;117(3):202-8.

PMID:
1672139
26.

Tumor necrosis factor-mediated hypoalbuminemia in rabbits.

Hennig B, Honchel R, Goldblum SE, McClain CJ.

J Nutr. 1988 Dec;118(12):1586-90.

PMID:
3210085

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