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Items: 1 to 50 of 230

1.

Long-term Evaluation of Allogeneic Bone Marrow-derived Mesenchymal Stromal Cell Therapy for Crohn's Disease Perianal Fistulas.

Barnhoorn MC, Wasser MNJM, Roelofs H, Maljaars PWJ, Molendijk I, Bonsing BA, Oosten LEM, Dijkstra G, van der Woude CJ, Roelen DL, Zwaginga JJ, Verspaget HW, Fibbe WE, Hommes DW, Peeters KCMJ, van der Meulen-de Jong AE.

J Crohns Colitis. 2020 Jan 1;14(1):64-70. doi: 10.1093/ecco-jcc/jjz116.

2.

A Multi-Level Fit-Based Quality Improvement Initiative to Improve Colorectal Cancer Screening in a Managed Care Population.

Yu C, Skootsky S, Grossman M, Garner OB, Betlachin A, Esrailian E, Hommes DW, May FP.

Clin Transl Gastroenterol. 2018 Sep 4;9(8):177. doi: 10.1038/s41424-018-0046-z.

3.

Standardization of mesenchymal stromal cell therapy for perianal fistulizing Crohn's disease.

Molendijk I, van der Meulen-de Jong AE, Verspaget HW, Veenendaal RA, Hommes DW, Bonsing BA, Peeters KCMJ.

Eur J Gastroenterol Hepatol. 2018 Oct;30(10):1148-1154. doi: 10.1097/MEG.0000000000001208.

PMID:
30095479
4.

Using insurance claims to predict and improve hospitalizations and biologics use in members with inflammatory bowel diseases.

Vaughn DA, van Deen WK, Kerr WT, Meyer TR, Bertozzi AL, Hommes DW, Cohen MS.

J Biomed Inform. 2018 May;81:93-101. doi: 10.1016/j.jbi.2018.03.015. Epub 2018 Apr 3.

5.

Clinical Pharmacokinetic and Pharmacodynamic Considerations in the Treatment of Inflammatory Bowel Disease.

Derijks LJJ, Wong DR, Hommes DW, van Bodegraven AA.

Clin Pharmacokinet. 2018 Sep;57(9):1075-1106. doi: 10.1007/s40262-018-0639-4. Review.

PMID:
29512050
6.

Long-term Outcome of Early Combined Immunosuppression Versus Conventional Management in Newly Diagnosed Crohn's Disease.

Hoekman DR, Stibbe JA, Baert FJ, Caenepeel P, Vergauwe P, De Vos M, Hommes DW, Benninga MA, Vermeire SA, D'Haens GR; BIRD (Belgian Inflammatory Bowel Disease Research and Development) Group; North-Holland Gut Club.

J Crohns Colitis. 2018 Apr 27;12(5):517-524. doi: 10.1093/ecco-jcc/jjy014.

PMID:
29401297
7.

The effect of arthropathies on illness perceptions, coping strategies, outcomes, and their changes over time in patients with inflammatory bowel disease: a 12-month follow-up study.

van Erp SJH, van der Have M, Fidder HH, van der Heijde D, Wolterbeek R, Hommes DW, Kaptein AA, van der Meulen-de Jong AE.

Eur J Gastroenterol Hepatol. 2018 Apr;30(4):465-470. doi: 10.1097/MEG.0000000000001066.

PMID:
29334517
8.

The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids.

Cao W, Kayama H, Chen ML, Delmas A, Sun A, Kim SY, Rangarajan ES, McKevitt K, Beck AP, Jackson CB, Crynen G, Oikonomopoulos A, Lacey PN, Martinez GJ, Izard T, Lorenz RG, Rodriguez-Palacios A, Cominelli F, Abreu MT, Hommes DW, Koralov SB, Takeda K, Sundrud MS.

Immunity. 2017 Dec 19;47(6):1182-1196.e10. doi: 10.1016/j.immuni.2017.11.012.

9.

Cohort profile: design and first results of the Dutch IBD Biobank: a prospective, nationwide biobank of patients with inflammatory bowel disease.

Spekhorst LM, Imhann F, Festen EAM, van Bodegraven AA, de Boer NKH, Bouma G, Fidder HH, d'Haens G, Hoentjen F, Hommes DW, de Jong DJ, Löwenberg M, Maljaars PWJ, van der Meulen-de Jong AE, Oldenburg B, Pierik MJ, Ponsioen CY, Stokkers PC, Verspaget HW, Visschedijk MC, van der Woude CJ, Dijkstra G, Weersma RK; Parelsnoer Institute (PSI) and the Dutch Initiative on Crohn and Colitis (ICC).

BMJ Open. 2017 Nov 8;7(11):e016695. doi: 10.1136/bmjopen-2017-016695.

10.

Autologous hematopoietic stem cells for refractory Crohn's disease.

DiNicola CA, Zand A, Hommes DW.

Expert Opin Biol Ther. 2017 May;17(5):555-564. doi: 10.1080/14712598.2017.1305355. Epub 2017 Mar 22. Review.

PMID:
28326848
11.

Five-year Safety Data From ENCORE, a European Observational Safety Registry for Adults With Crohn's Disease Treated With Infliximab [Remicade®] or Conventional Therapy.

D'Haens G, Reinisch W, Colombel JF, Panes J, Ghosh S, Prantera C, Lindgren S, Hommes DW, Huang Z, Boice J, Huyck S, Cornillie F; ENCORE investigators.

J Crohns Colitis. 2017 Jun 1;11(6):680-689. doi: 10.1093/ecco-jcc/jjw221.

PMID:
28025307
12.

Short article: Absence of serological rheumatoid arthritis biomarkers in inflammatory bowel disease patients with arthropathies.

Van Erp SJ, Verheul MK, Levarht EW, van der Reijden JJ, van der Heijde D, van Gaalen FA, Hommes DW, Norman GL, Shums Z, Mahler M, Verspaget HW, Trouw LA, van der Meulen-de Jong AE.

Eur J Gastroenterol Hepatol. 2017 Mar;29(3):345-348. doi: 10.1097/MEG.0000000000000805.

PMID:
27926664
13.

The impact of value-based healthcare for inflammatory bowel diseases on healthcare utilization: a pilot study.

van Deen WK, Spiro A, Burak Ozbay A, Skup M, Centeno A, Duran NE, Lacey PN, Jatulis D, Esrailian E, van Oijen MG, Hommes DW.

Eur J Gastroenterol Hepatol. 2017 Mar;29(3):331-337. doi: 10.1097/MEG.0000000000000782.

PMID:
27926663
14.

Is Stem Cell Therapy Ready for Prime Time in Treatment of Inflammatory Bowel Diseases?

Hawkey CJ, Hommes DW.

Gastroenterology. 2017 Feb;152(2):389-397.e2. doi: 10.1053/j.gastro.2016.11.003. Epub 2016 Nov 11.

PMID:
27845055
15.

Illness Perceptions and Outcomes in Patients with Inflammatory Bowel Disease: Is Coping a Mediator?

van Erp SJ, Brakenhoff LK, Vollmann M, van der Heijde D, Veenendaal RA, Fidder HH, Hommes DW, Kaptein AA, van der Meulen-de Jong AE, Scharloo M.

Int J Behav Med. 2017 Apr;24(2):205-214. doi: 10.1007/s12529-016-9599-y.

PMID:
27757843
16.

Informatics-Based Discovery of Disease-Associated Immune Profiles.

Delmas A, Oikonomopoulos A, Lacey PN, Fallahi M, Hommes DW, Sundrud MS.

PLoS One. 2016 Sep 26;11(9):e0163305. doi: 10.1371/journal.pone.0163305. eCollection 2016.

17.

Value redefined for inflammatory bowel disease patients: a choice-based conjoint analysis of patients' preferences.

van Deen WK, Nguyen D, Duran NE, Kane E, van Oijen MG, Hommes DW.

Qual Life Res. 2017 Feb;26(2):455-465. doi: 10.1007/s11136-016-1398-z. Epub 2016 Aug 31.

PMID:
27582169
18.

Identification of Circulating MicroRNA Signatures in Crohn's Disease Using the Nanostring nCounter Technology.

Oikonomopoulos A, Polytarchou C, Joshi S, Hommes DW, Iliopoulos D.

Inflamm Bowel Dis. 2016 Sep;22(9):2063-9. doi: 10.1097/MIB.0000000000000883.

PMID:
27542126
19.

Stem cell-based therapies in inflammatory bowel disease: promises and pitfalls.

Duran NE, Hommes DW.

Therap Adv Gastroenterol. 2016 Jul;9(4):533-47. doi: 10.1177/1756283X16642190. Epub 2016 Apr 25. Review.

20.

Defining a Patient Population With Cirrhosis: An Automated Algorithm With Natural Language Processing.

Chang EK, Yu CY, Clarke R, Hackbarth A, Sanders T, Esrailian E, Hommes DW, Runyon BA.

J Clin Gastroenterol. 2016 Nov/Dec;50(10):889-894.

PMID:
27348317
21.

Employment status, difficulties at work and quality of life in inflammatory bowel disease patients.

De Boer AG, Bennebroek Evertsz' F, Stokkers PC, Bockting CL, Sanderman R, Hommes DW, Sprangers MA, Frings-Dresen MH.

Eur J Gastroenterol Hepatol. 2016 Oct;28(10):1130-6. doi: 10.1097/MEG.0000000000000685.

PMID:
27340897
22.

Etrolizumab for ulcerative colitis: the new kid on the block?

Makker J, Hommes DW.

Expert Opin Biol Ther. 2016;16(4):567-72. doi: 10.1517/14712598.2016.1158807. Review.

PMID:
26914639
23.

Intraluminal Injection of Mesenchymal Stromal Cells in Spheroids Attenuates Experimental Colitis.

Molendijk I, Barnhoorn MC, de Jonge-Muller ES, Mieremet-Ooms MA, van der Reijden JJ, van der Helm D, Hommes DW, van der Meulen-de Jong AE, Verspaget HW.

J Crohns Colitis. 2016 Aug;10(8):953-64. doi: 10.1093/ecco-jcc/jjw047. Epub 2016 Feb 19.

PMID:
26896084
24.

Stem cells: HSCT for Crohn's disease: work in progress or a bridge too far?

Hommes DW, Lacey PN.

Nat Rev Gastroenterol Hepatol. 2016 Mar;13(3):128-30. doi: 10.1038/nrgastro.2016.22. Epub 2016 Feb 17. No abstract available.

PMID:
26882884
25.

Anti-TNF-α therapies for the treatment of Crohn's disease: the past, present and future.

Berns M, Hommes DW.

Expert Opin Investig Drugs. 2016;25(2):129-43. doi: 10.1517/13543784.2016.1126247. Epub 2016 Jan 8. Review.

PMID:
26616476
26.

Development and Validation of an Inflammatory Bowel Diseases Monitoring Index for Use With Mobile Health Technologies.

Van Deen WK, van der Meulen-de Jong AE, Parekh NK, Kane E, Zand A, DiNicola CA, Hall L, Inserra EK, Choi JM, Ha CY, Esrailian E, van Oijen MG, Hommes DW.

Clin Gastroenterol Hepatol. 2016 Dec;14(12):1742-1750.e7. doi: 10.1016/j.cgh.2015.10.035. Epub 2015 Nov 18.

PMID:
26598228
27.

Optimization of human mesenchymal stem cell manufacturing: the effects of animal/xeno-free media.

Oikonomopoulos A, van Deen WK, Manansala AR, Lacey PN, Tomakili TA, Ziman A, Hommes DW.

Sci Rep. 2015 Nov 13;5:16570. doi: 10.1038/srep16570.

28.

Classifying Back Pain and Peripheral Joint Complaints in Inflammatory Bowel Disease Patients: A Prospective Longitudinal Follow-up Study.

van Erp SJ, Brakenhoff LK, van Gaalen FA, van den Berg R, Fidder HH, Verspaget HW, Huizinga TW, Veenendaal RA, Wolterbeek R, van der Heijde D, van der Meulen-de Jong AE, Hommes DW.

J Crohns Colitis. 2016 Feb;10(2):166-75. doi: 10.1093/ecco-jcc/jjv195. Epub 2015 Oct 28.

PMID:
26512134
29.

Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling.

Rodriguez JA, Huerta-Yepez S, Law IK, Baay-Guzman GJ, Tirado-Rodriguez B, Hoffman JM, Iliopoulos D, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S.

Cell Mol Gastroenterol Hepatol. 2015 Nov 1;1(6):610-630.

30.

Assessment of Circulating MicroRNAs for the Diagnosis and Disease Activity Evaluation in Patients with Ulcerative Colitis by Using the Nanostring Technology.

Polytarchou C, Oikonomopoulos A, Mahurkar S, Touroutoglou A, Koukos G, Hommes DW, Iliopoulos D.

Inflamm Bowel Dis. 2015 Nov;21(11):2533-9. doi: 10.1097/MIB.0000000000000547.

PMID:
26313695
31.

Predicting Endoscopic Disease Activity in Crohn's Disease: A New and Validated Noninvasive Disease Activity Index (The Utrecht Activity Index).

Minderhoud IM, Steyerberg EW, van Bodegraven AA, van der Woude CJ, Hommes DW, Dijkstra G, Fidder HH, Schwartz MP, Oldenburg B.

Inflamm Bowel Dis. 2015 Oct;21(10):2453-9. doi: 10.1097/MIB.0000000000000507.

PMID:
26181428
32.

Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells Promote Healing of Refractory Perianal Fistulas in Patients With Crohn's Disease.

Molendijk I, Bonsing BA, Roelofs H, Peeters KC, Wasser MN, Dijkstra G, van der Woude CJ, Duijvestein M, Veenendaal RA, Zwaginga JJ, Verspaget HW, Fibbe WE, van der Meulen-de Jong AE, Hommes DW.

Gastroenterology. 2015 Oct;149(4):918-27.e6. doi: 10.1053/j.gastro.2015.06.014. Epub 2015 Jun 25.

PMID:
26116801
33.

Presenteeism in Inflammatory Bowel Diseases: A Hidden Problem with Significant Economic Impact.

Zand A, van Deen WK, Inserra EK, Hall L, Kane E, Centeno A, Choi JM, Ha CY, Esrailian E, DʼHaens GR, Hommes DW.

Inflamm Bowel Dis. 2015 Jul;21(7):1623-30. doi: 10.1097/MIB.0000000000000399.

PMID:
26070004
34.

MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice.

Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D.

Gastroenterology. 2015 Oct;149(4):981-92.e11. doi: 10.1053/j.gastro.2015.05.057. Epub 2015 Jun 6.

35.

A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium.

Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D.

Inflamm Bowel Dis. 2015 May;21(5):996-1005. doi: 10.1097/MIB.0000000000000339.

36.

Value-based health care for inflammatory bowel diseases.

van Deen WK, Esrailian E, Hommes DW.

J Crohns Colitis. 2015 May;9(5):421-7. doi: 10.1093/ecco-jcc/jjv036. Epub 2015 Feb 16. Review.

PMID:
25687204
37.

Back/joint pain, illness perceptions and coping are important predictors of quality of life and work productivity in patients with inflammatory bowel disease: a 12-month longitudinal study.

van der Have M, Brakenhoff LK, van Erp SJ, Kaptein AA, Leenders M, Scharloo M, Veenendaal RA, van der Heijde DM, van der Meulen-de Jong AE, Hommes DW, Fidder HH.

J Crohns Colitis. 2015 Mar;9(3):276-83. doi: 10.1093/ecco-jcc/jju025. Epub 2014 Dec 28.

PMID:
25547976
38.

How does a gastroenterologist show value?

Hommes DW, Esrailian E.

Clin Gastroenterol Hepatol. 2015 Mar;13(3):616-7. doi: 10.1016/j.cgh.2014.10.024. Epub 2014 Oct 28. No abstract available.

PMID:
25445770
39.

The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.

Voorneveld PW, Kodach LL, Jacobs RJ, van Noesel CJ, Peppelenbosch MP, Korkmaz KS, Molendijk I, Dekker E, Morreau H, van Pelt GW, Tollenaar RA, Mesker W, Hawinkels LJ, Paauwe M, Verspaget HW, Geraets DT, Hommes DW, Offerhaus GJ, van den Brink GR, Ten Dijke P, Hardwick JC.

Br J Cancer. 2015 Jan 6;112(1):122-30. doi: 10.1038/bjc.2014.560. Epub 2014 Nov 13.

40.

Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones.

Amos-Landgraf JM, Heijmans J, Wielenga MC, Dunkin E, Krentz KJ, Clipson L, Ederveen AG, Groothuis PG, Mosselman S, Muncan V, Hommes DW, Shedlovsky A, Dove WF, van den Brink GR.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16514-9. doi: 10.1073/pnas.1323064111. Epub 2014 Nov 3.

41.

A nationwide 2010-2012 analysis of U.S. health care utilization in inflammatory bowel diseases.

van Deen WK, van Oijen MG, Myers KD, Centeno A, Howard W, Choi JM, Roth BE, McLaughlin EM, Hollander D, Wong-Swanson B, Sack J, Ong MK, Ha CY, Esrailian E, Hommes DW.

Inflamm Bowel Dis. 2014 Oct;20(10):1747-53. doi: 10.1097/MIB.0000000000000139.

PMID:
25137415
42.

Repurposing miltefosine for the treatment of immune-mediated disease?

Verhaar AP, Wildenberg ME, Peppelenbosch MP, Hommes DW, van den Brink GR.

J Pharmacol Exp Ther. 2014 Aug;350(2):189-95. doi: 10.1124/jpet.113.212654. Epub 2014 May 15.

PMID:
24833702
43.

Magnetic resonance imaging of the hand joints in patients with inflammatory bowel disease and arthralgia: a pilot study.

Brakenhoff LK, Stomp W, van Gaalen FA, Hommes DW, Bloem JL, van der Heijde DM, Fidder HH, Reijnierse M.

Scand J Rheumatol. 2014;43(5):416-8. doi: 10.3109/03009742.2014.882407. Epub 2014 Apr 11.

PMID:
24720480
44.

Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.

Voorneveld PW, Kodach LL, Jacobs RJ, Liv N, Zonnevylle AC, Hoogenboom JP, Biemond I, Verspaget HW, Hommes DW, de Rooij K, van Noesel CJ, Morreau H, van Wezel T, Offerhaus GJ, van den Brink GR, Peppelenbosch MP, Ten Dijke P, Hardwick JC.

Gastroenterology. 2014 Jul;147(1):196-208.e13. doi: 10.1053/j.gastro.2014.03.052. Epub 2014 Apr 3.

PMID:
24704720
45.

Treatment of bone loss in osteopenic patients with Crohn's disease: a double-blind, randomised trial of oral risedronate 35 mg once weekly or placebo, concomitant with calcium and vitamin D supplementation.

van Bodegraven AA, Bravenboer N, Witte BI, Dijkstra G, van der Woude CJ, Stokkers PC, Russel MG, Oldenburg B, Pierik M, Roos JC, van Hogezand RA, Dik VK, Oostlander AE, Netelenbos JC, van de Langerijt L, Hommes DW, Lips P; Dutch Initiative on Crohn and Colitis (ICC).

Gut. 2014 Sep;63(9):1424-30. doi: 10.1136/gutjnl-2013-305523. Epub 2013 Oct 21.

PMID:
24146170
46.

Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease.

Cleynen I, Vazeille E, Artieda M, Verspaget HW, Szczypiorska M, Bringer MA, Lakatos PL, Seibold F, Parnell K, Weersma RK, Mahachie John JM, Morgan-Walsh R, Staelens D, Arijs I, De Hertogh G, Müller S, Tordai A, Hommes DW, Ahmad T, Wijmenga C, Pender S, Rutgeerts P, Van Steen K, Lottaz D, Vermeire S, Darfeuille-Michaud A.

Gut. 2014 Aug;63(8):1265-74. doi: 10.1136/gutjnl-2012-303205. Epub 2013 Oct 3.

PMID:
24092863
47.

Mucosal schwann cell hamartoma in ulcerative colitis: diagnosis and clinical relevance.

van Deen WK, Hommes DW.

Gastroenterol Hepatol (N Y). 2013 Mar;9(3):185-6. No abstract available.

48.

The course of inflammatory bowel disease during pregnancy and postpartum: a prospective European ECCO-EpiCom Study of 209 pregnant women.

Pedersen N, Bortoli A, Duricova D, D Inca R, Panelli MR, Gisbert JP, Zoli G, López-Sanromán A, Castiglione F, Riegler G, Annese V, Gionchetti P, Prada A, Pont ED, Timmer A, Felley C, Shuhaibar M, Tsianos EV, Dejaco C, Baert FJ, Jess T, Lebech M, Hommes DW, Munkholm P; European Crohn-Colitis Organisation-ECCO-Study Group of Epidemiology Committee-EpiCom.

Aliment Pharmacol Ther. 2013 Sep;38(5):501-12. doi: 10.1111/apt.12412. Epub 2013 Jul 15.

49.

A rapid assay for on-site monitoring of infliximab trough levels: a feasibility study.

Corstjens PL, Fidder HH, Wiesmeijer KC, de Dood CJ, Rispens T, Wolbink GJ, Hommes DW, Tanke HJ.

Anal Bioanal Chem. 2013 Sep;405(23):7367-75. doi: 10.1007/s00216-013-7154-0. Epub 2013 Jul 9.

PMID:
23836086
50.

IBD: Antibodies to anti-TNF therapy--consequences for IBD management.

van Deen WK, Hommes DW.

Nat Rev Gastroenterol Hepatol. 2013 Aug;10(8):446-8. doi: 10.1038/nrgastro.2013.118. Epub 2013 Jul 2. No abstract available.

PMID:
23817324

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