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Items: 1 to 50 of 222

1.

Transcriptional regulatory model of fibrosis progression in the human lung.

McDonough JE, Ahangari F, Li Q, Jain S, Verleden SE, Herazo-Maya J, Vukmirovic M, DeIuliis G, Tzouvelekis A, Tanabe N, Chu F, Yan X, Verschakelen J, Homer RJ, Manatakis DV, Zhang J, Ding J, Maes K, De Sadeleer L, Vos R, Neyrinck A, Benos PV, Bar-Joseph Z, Tantin D, Hogg JC, Vanaudenaerde BM, Wuyts WA, Kaminski N.

JCI Insight. 2019 Nov 14;4(22). pii: 131597. doi: 10.1172/jci.insight.131597.

2.

A Semiquantitative Scoring System May Allow Biopsy Diagnosis of Pulmonary Large Cell Neuroendocrine Carcinoma.

Baine MK, Sinard JH, Cai G, Homer RJ.

Am J Clin Pathol. 2019 Oct 8. pii: aqz149. doi: 10.1093/ajcp/aqz149. [Epub ahead of print]

PMID:
31593583
3.

Differences in Pathology, Staging, and Treatment between HIV+ and Uninfected Patients with Microscopically Confirmed Hepatocellular Carcinoma.

Torgersen J, Taddei TH, Park LS, Carbonari DM, Kallan MJ, Mitchell Richards K, Zhang X, Jhala D, Bräu N, Homer R, D'Addeo K, Mehta R, Skanderson M, Kidwai-Khan F, Justice AC, Lo Re V  III.

Cancer Epidemiol Biomarkers Prev. 2019 Oct 1. doi: 10.1158/1055-9965.EPI-19-0503. [Epub ahead of print]

PMID:
31575557
4.

Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors.

Ayeni D, Miller B, Kuhlmann A, Ho PC, Robles-Oteiza C, Gaefele M, Levy S, de Miguel FJ, Perry C, Guan T, Krystal G, Lockwood W, Zelterman D, Homer R, Liu Z, Kaech S, Politi K.

J Immunother Cancer. 2019 Jul 10;7(1):172. doi: 10.1186/s40425-019-0643-8.

5.

Reanalysis of the NCCN PD-L1 companion diagnostic assay study for lung cancer in the context of PD-L1 expression findings in triple-negative breast cancer.

Rimm DL, Han G, Taube JM, Yi ES, Bridge JA, Flieder DB, Homer R, Roden AC, Hirsch FR, Wistuba II, Pusztai L.

Breast Cancer Res. 2019 Jun 13;21(1):72. doi: 10.1186/s13058-019-1156-6.

6.

Low ambient humidity impairs barrier function and innate resistance against influenza infection.

Kudo E, Song E, Yockey LJ, Rakib T, Wong PW, Homer RJ, Iwasaki A.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):10905-10910. doi: 10.1073/pnas.1902840116. Epub 2019 May 13.

7.

False-positive pathology: improving reproducibility with the next generation of pathologists.

Mazer BL, Homer RJ, Rimm DL.

Lab Invest. 2019 Sep;99(9):1260-1265. doi: 10.1038/s41374-019-0257-2. Epub 2019 Apr 24.

PMID:
31019290
8.

Short Tandem Repeats Define a Gestational Origin for Metastatic Choriocarcinoma.

Brown K, Homer R, Baine M, Blasberg JD.

Ann Thorac Surg. 2019 Aug;108(2):e115-e117. doi: 10.1016/j.athoracsur.2018.12.038. Epub 2019 Jan 24.

PMID:
30685255
9.

Multimodality Imaging Involving Magnetic Resonance Facilitates Giant Symptomatic Myxoma Resection.

Hur DJ, Prescher LM, Meadows JL, Pfau SE, Homer RJ, Tellides G, Yun JJ.

Ann Thorac Surg. 2019 Jan;107(1):e15-e17. doi: 10.1016/j.athoracsur.2018.05.083. Epub 2018 Jul 2.

PMID:
30558736
10.

24/7/365 Neuroradiologist Coverage Improves Resident Perception of Educational Experience, Referring Physician Satisfaction, and Turnaround Time.

Spitler K, Vijayasarathi A, Salehi B, Dua S, Azizyan A, Cekic M, Yaghmai N, Homer R, Salamon N.

Curr Probl Diagn Radiol. 2018 Oct 9. pii: S0363-0188(18)30156-7. doi: 10.1067/j.cpradiol.2018.09.004. [Epub ahead of print]

PMID:
30391225
11.

A rare presentation of pulmonary sarcoidosis as a solitary lung mass: a case report.

Kelleher DW, Yaggi M, Homer R, Herzog EL, Ryu C.

J Med Case Rep. 2018 Apr 13;12(1):94. doi: 10.1186/s13256-018-1632-0.

12.

Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function.

Yu G, Tzouvelekis A, Wang R, Herazo-Maya JD, Ibarra GH, Srivastava A, de Castro JPW, DeIuliis G, Ahangari F, Woolard T, Aurelien N, Arrojo E Drigo R, Gan Y, Graham M, Liu X, Homer RJ, Scanlan TS, Mannam P, Lee PJ, Herzog EL, Bianco AC, Kaminski N.

Nat Med. 2018 Jan;24(1):39-49. doi: 10.1038/nm.4447. Epub 2017 Dec 4.

13.

Diagnosing idiopathic pulmonary fibrosis without a lung biopsy: honeycombing not required.

Homer R, Lederer DJ.

Thorax. 2017 May;72(5):391-392. doi: 10.1136/thoraxjnl-2016-209831. Epub 2017 Mar 9. No abstract available.

PMID:
28280234
14.

A Prospective, Multi-institutional, Pathologist-Based Assessment of 4 Immunohistochemistry Assays for PD-L1 Expression in Non-Small Cell Lung Cancer.

Rimm DL, Han G, Taube JM, Yi ES, Bridge JA, Flieder DB, Homer R, West WW, Wu H, Roden AC, Fujimoto J, Yu H, Anders R, Kowalewski A, Rivard C, Rehman J, Batenchuk C, Burns V, Hirsch FR, Wistuba II.

JAMA Oncol. 2017 Aug 1;3(8):1051-1058. doi: 10.1001/jamaoncol.2017.0013.

15.

Zika virus causes testicular atrophy.

Uraki R, Hwang J, Jurado KA, Householder S, Yockey LJ, Hastings AK, Homer RJ, Iwasaki A, Fikrig E.

Sci Adv. 2017 Feb 22;3(2):e1602899. doi: 10.1126/sciadv.1602899. eCollection 2017 Feb.

16.

Upper Airway Obstruction Requiring Emergent Tracheostomy Secondary to Laryngeal Sarcoidosis: A Case Report.

Ryu C, Herzog EL, Pan H, Homer R, Gulati M.

Am J Case Rep. 2017 Feb 13;18:157-159.

17.

Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis.

Vukmirovic M, Herazo-Maya JD, Blackmon J, Skodric-Trifunovic V, Jovanovic D, Pavlovic S, Stojsic J, Zeljkovic V, Yan X, Homer R, Stefanovic B, Kaminski N.

BMC Pulm Med. 2017 Jan 12;17(1):15. doi: 10.1186/s12890-016-0356-4.

18.

Inhibition of Regulatory-Associated Protein of Mechanistic Target of Rapamycin Prevents Hyperoxia-Induced Lung Injury by Enhancing Autophagy and Reducing Apoptosis in Neonatal Mice.

Sureshbabu A, Syed M, Das P, Janér C, Pryhuber G, Rahman A, Andersson S, Homer RJ, Bhandari V.

Am J Respir Cell Mol Biol. 2016 Nov;55(5):722-735.

19.

SH2 Domain-Containing Phosphatase-2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis.

Tzouvelekis A, Yu G, Lino Cardenas CL, Herazo-Maya JD, Wang R, Woolard T, Zhang Y, Sakamoto K, Lee H, Yi JS, DeIuliis G, Xylourgidis N, Ahangari F, Lee PJ, Aidinis V, Herzog EL, Homer R, Bennett AM, Kaminski N.

Am J Respir Crit Care Med. 2017 Feb 15;195(4):500-514. doi: 10.1164/rccm.201602-0329OC.

20.

Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis.

Peng X, Moore M, Mathur A, Zhou Y, Sun H, Gan Y, Herazo-Maya JD, Kaminski N, Hu X, Pan H, Ryu C, Osafo-Addo A, Homer RJ, Feghali-Bostwick C, Fares WH, Gulati M, Hu B, Lee CG, Elias JA, Herzog EL.

FASEB J. 2016 Dec;30(12):4056-4070. Epub 2016 Sep 8.

21.

Matrix Metalloproteinase-Targeted Imaging of Lung Inflammation and Remodeling.

Golestani R, Razavian M, Ye Y, Zhang J, Jung JJ, Toczek J, Gona K, Kim HY, Elias JA, Lee CG, Homer RJ, Sadeghi MM.

J Nucl Med. 2017 Jan;58(1):138-143. doi: 10.2967/jnumed.116.176198. Epub 2016 Jul 28.

22.

Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells.

Forloni M, Gupta R, Nagarajan A, Sun LS, Dong Y, Pirazzoli V, Toki M, Wurtz A, Melnick MA, Kobayashi S, Homer RJ, Rimm DL, Gettinger SJ, Politi K, Dogra SK, Wajapeyee N.

Cell Rep. 2016 Jul 12;16(2):457-471. doi: 10.1016/j.celrep.2016.05.087. Epub 2016 Jun 23.

23.

The Airway in Idiopathic Pulmonary Fibrosis: Protecting the Lung or Promoting Disease?

Ryu C, Homer RJ, Herzog EL.

Am J Respir Crit Care Med. 2016 May 15;193(10):1081-2. doi: 10.1164/rccm.201601-0055ED. No abstract available.

24.

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease.

Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, Staeheli P, Iwasaki A.

Science. 2016 Apr 22;352(6284):463-6. doi: 10.1126/science.aaf3926.

25.

Getting undergraduate medical students involved in research.

Patel SB, Bennett T, Bradley A, Homer R, Sinha A.

Educ Health (Abingdon). 2016 Jan-Apr;29(1):56. doi: 10.4103/1357-6283.178934. No abstract available.

26.

Endobronchial Ultrasound-Guided Cautery-Assisted Transbronchial Forceps Biopsies: Safety and Sensitivity Relative to Transbronchial Needle Aspiration.

Bramley K, Pisani MA, Murphy TE, Araujo KL, Homer RJ, Puchalski JT.

Ann Thorac Surg. 2016 May;101(5):1870-6. doi: 10.1016/j.athoracsur.2015.11.051. Epub 2016 Feb 22.

27.

Increased susceptibility of Cftr-/- mice to LPS-induced lung remodeling.

Bruscia EM, Zhang PX, Barone C, Scholte BJ, Homer R, Krause DS, Egan ME.

Am J Physiol Lung Cell Mol Physiol. 2016 Apr 15;310(8):L711-9. doi: 10.1152/ajplung.00284.2015. Epub 2016 Feb 5.

28.

Role of Nitric Oxide Isoforms in Vascular and Alveolar Development and Lung Injury in Vascular Endothelial Growth Factor Overexpressing Neonatal Mice Lungs.

Syed MA, Choo-Wing R, Homer RJ, Bhandari V.

PLoS One. 2016 Jan 22;11(1):e0147588. doi: 10.1371/journal.pone.0147588. eCollection 2016.

29.

Comparison of Transbronchial and Cryobiopsies in Evaluation of Diffuse Parenchymal Lung Disease.

Ramaswamy A, Homer R, Killam J, Pisani MA, Murphy TE, Araujo K, Puchalski J.

J Bronchology Interv Pulmonol. 2016 Jan;23(1):14-21. doi: 10.1097/LBR.0000000000000246.

30.

Molar incisor hypomineralisation: experience and perceived challenges among dentists specialising in paediatric dentistry and a group of general dental practitioners in the UK.

Kalkani M, Balmer RC, Homer RM, Day PF, Duggal MS.

Eur Arch Paediatr Dent. 2016 Apr;17(2):81-8. doi: 10.1007/s40368-015-0209-5. Epub 2015 Nov 27.

PMID:
26613718
31.

Suppression of NLRX1 in chronic obstructive pulmonary disease.

Kang MJ, Yoon CM, Kim BH, Lee CM, Zhou Y, Sauler M, Homer R, Dhamija A, Boffa D, West AP, Shadel GS, Ting JP, Tedrow JR, Kaminski N, Kim WJ, Lee CG, Oh YM, Elias JA.

J Clin Invest. 2015 Jun;125(6):2458-62. doi: 10.1172/JCI71747. Epub 2015 May 4.

32.
33.

Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung.

Sureshbabu A, Syed MA, Boddupalli CS, Dhodapkar MV, Homer RJ, Minoo P, Bhandari V.

Respir Res. 2015 Jan 16;16:4. doi: 10.1186/s12931-014-0162-6.

34.

IL-6 receptor α defines effector memory CD8+ T cells producing Th2 cytokines and expanding in asthma.

Lee N, You S, Shin MS, Lee WW, Kang KS, Kim SH, Kim WU, Homer RJ, Kang MJ, Montgomery RR, Dela Cruz CS, Shaw AC, Lee PJ, Chupp GL, Hwang D, Kang I.

Am J Respir Crit Care Med. 2014 Dec 15;190(12):1383-94. doi: 10.1164/rccm.201403-0601OC.

35.

Cathepsin E promotes pulmonary emphysema via mitochondrial fission.

Zhang X, Shan P, Homer R, Zhang Y, Petrache I, Mannam P, Lee PJ.

Am J Pathol. 2014 Oct;184(10):2730-41. doi: 10.1016/j.ajpath.2014.06.017.

36.

Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis.

Zhou Y, Peng H, Sun H, Peng X, Tang C, Gan Y, Chen X, Mathur A, Hu B, Slade MD, Montgomery RR, Shaw AC, Homer RJ, White ES, Lee CM, Moore MW, Gulati M, Lee CG, Elias JA, Herzog EL.

Sci Transl Med. 2014 Jun 11;6(240):240ra76. doi: 10.1126/scitranslmed.3007096.

37.

CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung.

Peng X, Moore MW, Peng H, Sun H, Gan Y, Homer RJ, Herzog EL.

Front Pharmacol. 2014 May 16;5:80. doi: 10.3389/fphar.2014.00080. eCollection 2014.

38.

An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection.

Lafferty EI, Flaczyk A, Angers I, Homer R, d'Hennezel E, Malo D, Piccirillo CA, Vidal SM, Qureshi ST.

Genes Immun. 2014 Jul-Aug;15(5):320-32. doi: 10.1038/gene.2014.22. Epub 2014 May 22.

39.

A critical regulatory role for macrophage migration inhibitory factor in hyperoxia-induced injury in the developing murine lung.

Sun H, Choo-Wing R, Sureshbabu A, Fan J, Leng L, Yu S, Jiang D, Noble P, Homer RJ, Bucala R, Bhandari V.

PLoS One. 2013 Apr 29;8(4):e60560. doi: 10.1371/journal.pone.0060560. Print 2013.

40.

Role of tissue protection in lethal respiratory viral-bacterial coinfection.

Jamieson AM, Pasman L, Yu S, Gamradt P, Homer RJ, Decker T, Medzhitov R.

Science. 2013 Jun 7;340(6137):1230-4. doi: 10.1126/science.1233632. Epub 2013 Apr 25.

41.

Identification of EGFR mutation, KRAS mutation, and ALK gene rearrangement in cytological specimens of primary and metastatic lung adenocarcinoma.

Cai G, Wong R, Chhieng D, Levy GH, Gettinger SN, Herbst RS, Puchalski JT, Homer RJ, Hui P.

Cancer Cytopathol. 2013 Sep;121(9):500-7. doi: 10.1002/cncy.21288. Epub 2013 Mar 12.

42.

Hyperoxia and interferon-γ-induced injury in developing lungs occur via cyclooxygenase-2 and the endoplasmic reticulum stress-dependent pathway.

Choo-Wing R, Syed MA, Harijith A, Bowen B, Pryhuber G, Janér C, Andersson S, Homer RJ, Bhandari V.

Am J Respir Cell Mol Biol. 2013 Jun;48(6):749-57. doi: 10.1165/rcmb.2012-0381OC.

43.

Making the grade: Charge nurse education improves job performance.

Homer R, Ryan L.

Nurs Manage. 2013 Mar;44(3):38-44. doi: 10.1097/01.NUMA.0000427183.65177.76. No abstract available.

PMID:
23435107
44.

Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis.

Reilkoff RA, Peng H, Murray LA, Peng X, Russell T, Montgomery R, Feghali-Bostwick C, Shaw A, Homer RJ, Gulati M, Mathur A, Elias JA, Herzog EL.

Am J Respir Crit Care Med. 2013 Jan 15;187(2):180-8. doi: 10.1164/rccm.201206-1109OC. Epub 2012 Dec 6.

45.

IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension.

Cho WK, Lee CM, Kang MJ, Huang Y, Giordano FJ, Lee PJ, Trow TK, Homer RJ, Sessa WC, Elias JA, Lee CG.

Am J Physiol Lung Cell Mol Physiol. 2013 Jan 15;304(2):L112-24. doi: 10.1152/ajplung.00101.2012. Epub 2012 Nov 2.

46.

Susceptibility to progressive Cryptococcus neoformans pulmonary infection is regulated by loci on mouse chromosomes 1 and 9.

Carroll SF, Lafferty EI, Flaczyk A, Fujiwara TM, Homer R, Morgan K, Loredo-Osti JC, Qureshi ST.

Infect Immun. 2012 Dec;80(12):4167-76. doi: 10.1128/IAI.00417-12. Epub 2012 Sep 17.

47.

Chronic inflammation and lung fibrosis: pleotropic syndromes but limited distinct phenotypes.

Gifford AH, Matsuoka M, Ghoda LY, Homer RJ, Enelow RI.

Mucosal Immunol. 2012 Sep;5(5):480-4. doi: 10.1038/mi.2012.68. Epub 2012 Jul 18. Review.

PMID:
22806097
48.

Interstitial lung disease in the connective tissue diseases.

Antin-Ozerkis D, Rubinowitz A, Evans J, Homer RJ, Matthay RA.

Clin Chest Med. 2012 Mar;33(1):123-49. doi: 10.1016/j.ccm.2012.01.004. Review.

PMID:
22365251
49.

Increased hyperoxia-induced lung injury in nitric oxide synthase 2 null mice is mediated via angiopoietin 2.

Bhandari V, Choo-Wing R, Harijith A, Sun H, Syed MA, Homer RJ, Elias JA.

Am J Respir Cell Mol Biol. 2012 May;46(5):668-76. doi: 10.1165/rcmb.2011-0074OC. Epub 2012 Jan 6.

50.

Approach to the ground-glass nodule.

Detterbeck FC, Homer RJ.

Clin Chest Med. 2011 Dec;32(4):799-810. doi: 10.1016/j.ccm.2011.08.002. Epub 2011 Oct 2. Review.

PMID:
22054887

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