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Items: 1 to 50 of 174

1.

Development of Novel Silyl Cyanocinnamic Acid Derivatives as Metabolic Plasticity Inhibitors for Cancer Treatment.

Nelson GL, Ronayne CT, Solano LN, Jonnalagadda SK, Jonnalagadda S, Rumbley J, Holy J, Rose-Hellekant T, Drewes LR, Mereddy VR.

Sci Rep. 2019 Dec 4;9(1):18266. doi: 10.1038/s41598-019-54709-7.

2.

Five-year outcomes in cardiac surgery patients with atrial fibrillation undergoing concomitant surgical ablation versus no ablation. The long-term follow-up of the PRAGUE-12 Study.

Osmancik P, Budera P, Talavera D, Hlavicka J, Herman D, Holy J, Cervinka P, Smid J, Hanak P, Hatala R, Widimsky P.

Heart Rhythm. 2019 Sep;16(9):1334-1340. doi: 10.1016/j.hrthm.2019.05.001. Epub 2019 May 10.

PMID:
31082538
3.

Novel N,N-dialkyl cyanocinnamic acids as monocarboxylate transporter 1 and 4 inhibitors.

Jonnalagadda S, Jonnalagadda SK, Ronayne CT, Nelson GL, Solano LN, Rumbley J, Holy J, Mereddy VR, Drewes LR.

Oncotarget. 2019 Mar 22;10(24):2355-2368. doi: 10.18632/oncotarget.26760. eCollection 2019 Mar 22.

4.

Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells.

Magalhães-Novais S, Bermejo-Millo JC, Loureiro R, Mesquita KA, Domingues MR, Maciel E, Melo T, Baldeiras I, Erickson JR, Holy J, Potes Y, Coto-Montes A, Oliveira PJ, Vega-Naredo I.

Autophagy. 2020 Feb;16(2):313-333. doi: 10.1080/15548627.2019.1607694. Epub 2019 Apr 24.

PMID:
30990357
5.

Two-photon fluorescence lifetime imaging of intrinsic NADH in three-dimensional tumor models.

Cong A, Pimenta RML, Lee HB, Mereddy V, Holy J, Heikal AA.

Cytometry A. 2019 Jan;95(1):80-92. doi: 10.1002/cyto.a.23632. Epub 2018 Oct 21.

6.

Toxicity of lupane derivatives on anionic membrane models, isolated rat mitochondria and selected human cell lines: Role of terminal alkyl chains.

Carvalho FS, Morais CM, Holy J, Krasutsky D, Yemets SV, Krasutsky PA, Jurado AS, Oliveira PJ, Serafim TL.

Chem Biol Interact. 2018 Dec 25;296:198-210. doi: 10.1016/j.cbi.2018.10.002. Epub 2018 Oct 4.

PMID:
30292691
7.

A tRNA fragment, tRF5-Glu, regulates BCAR3 expression and proliferation in ovarian cancer cells.

Zhou K, Diebel KW, Holy J, Skildum A, Odean E, Hicks DA, Schotl B, Abrahante JE, Spillman MA, Bemis LT.

Oncotarget. 2017 Sep 8;8(56):95377-95391. doi: 10.18632/oncotarget.20709. eCollection 2017 Nov 10.

8.

Synthesis and biological evaluation of 2-alkoxycarbonylallyl esters as potential anticancer agents.

Ronayne CT, Solano LN, Nelson GL, Lueth EA, Hubbard SL, Schumacher TJ, Gardner ZS, Jonnalagadda SK, Gurrapu S, Holy J, Mereddy VR.

Bioorg Med Chem Lett. 2017 Feb 15;27(4):776-780. doi: 10.1016/j.bmcl.2017.01.037. Epub 2017 Jan 17.

PMID:
28129978
9.

Interventional left atrial appendage closure vs novel anticoagulation agents in patients with atrial fibrillation indicated for long-term anticoagulation (PRAGUE-17 study).

Osmancik P, Tousek P, Herman D, Neuzil P, Hala P, Stasek J, Haman L, Kala P, Poloczek M, Branny M, Chovancik J, Cervinka P, Holy J, Vancura V, Rokyta R, Taborsky M, Kovarnik T, Zemanek D, Peichl P, Haskova S, Jarkovsky J, Widimsky P; PRAGUE-17 Investigators.

Am Heart J. 2017 Jan;183:108-114. doi: 10.1016/j.ahj.2016.10.003. Epub 2016 Oct 11.

PMID:
27979034
10.

A Cancer Cell Spheroid Assay to Assess Invasion in a 3D Setting.

Berens EB, Holy JM, Riegel AT, Wellstein A.

J Vis Exp. 2015 Nov 20;(105). doi: 10.3791/53409.

11.

Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts.

Moreira AC, Branco AF, Sampaio SF, Cunha-Oliveira T, Martins TR, Holy J, Oliveira PJ, Sardão VA.

Biochim Biophys Acta. 2014 Dec;1842(12 Pt A):2468-78. doi: 10.1016/j.bbadis.2014.09.015. Epub 2014 Oct 2.

12.

New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death.

Serafim TL, Carvalho FS, Bernardo TC, Pereira GC, Perkins E, Holy J, Krasutsky DA, Kolomitsyna ON, Krasutsky PA, Oliveira PJ.

Bioorg Med Chem. 2014 Nov 1;22(21):6270-87. doi: 10.1016/j.bmc.2014.08.013. Epub 2014 Sep 6.

PMID:
25245673
13.

Mitochondrial metabolism directs stemness and differentiation in P19 embryonal carcinoma stem cells.

Vega-Naredo I, Loureiro R, Mesquita KA, Barbosa IA, Tavares LC, Branco AF, Erickson JR, Holy J, Perkins EL, Carvalho RA, Oliveira PJ.

Cell Death Differ. 2014 Oct;21(10):1560-74. doi: 10.1038/cdd.2014.66. Epub 2014 May 16.

14.

Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition.

Bernardo TC, Cunha-Oliveira T, Serafim TL, Holy J, Krasutsky D, Kolomitsyna O, Krasutsky P, Moreno AM, Oliveira PJ.

Bioorg Med Chem. 2013 Dec 1;21(23):7239-49. doi: 10.1016/j.bmc.2013.09.066. Epub 2013 Oct 8.

PMID:
24156937
15.

Vital imaging of multicellular spheroids.

Oliveira PJ, Perkins EL, Holy J.

Methods Mol Biol. 2014;1075:227-41. doi: 10.1007/978-1-60761-847-8_11.

PMID:
24052355
16.

Differentiation-dependent doxorubicin toxicity on H9c2 cardiomyoblasts.

Branco AF, Sampaio SF, Moreira AC, Holy J, Wallace KB, Baldeiras I, Oliveira PJ, Sardão VA.

Cardiovasc Toxicol. 2012 Dec;12(4):326-40. doi: 10.1007/s12012-012-9177-8.

PMID:
22744233
17.

An unusual presentation of celiac disease in a middle-aged man treated for hypertension: a case report.

Holý J, Keczkemethy Z, Přádná J, Havránek P.

Gastroenterol Nurs. 2012 Jan-Feb;35(1):65-8. doi: 10.1097/SGA.0b013e31824035e4. No abstract available.

PMID:
22306731
18.

Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells.

Serafim TL, Carvalho FS, Marques MP, Calheiros R, Silva T, Garrido J, Milhazes N, Borges F, Roleira F, Silva ET, Holy J, Oliveira PJ.

Chem Res Toxicol. 2011 May 16;24(5):763-74. doi: 10.1021/tx200126r. Epub 2011 Apr 28.

PMID:
21504213
19.

Adhesion, proliferation and differentiation of pluripotent stem cells on multi-walled carbon nanotubes.

Holy J, Perkins E, Yu X.

IET Nanobiotechnol. 2011 Jun;5(2):41-6. doi: 10.1049/iet-nbt.2010.0014.

PMID:
21495779
20.

Isoproterenol cytotoxicity is dependent on the differentiation state of the cardiomyoblast H9c2 cell line.

Branco AF, Pereira SL, Moreira AC, Holy J, Sardão VA, Oliveira PJ.

Cardiovasc Toxicol. 2011 Sep;11(3):191-203. doi: 10.1007/s12012-011-9111-5. Erratum in: Cardiovasc Toxicol. 2011 Sep;11(3):284.

PMID:
21455642
21.

Biologic activity of a dinuclear Pd(II)-spermine complex toward human breast cancer.

Fiuza SM, Holy J, Batista de Carvalho LA, Marques MP.

Chem Biol Drug Des. 2011 Jun;77(6):477-88. doi: 10.1111/j.1747-0285.2011.01081.x. Epub 2011 Apr 1.

PMID:
21371266
22.

[May-Thurner syndrome].

Kecskeméthy Z, Holý J.

Orv Hetil. 2011 Jan 23;152(4):139-41. doi: 10.1556/OH.2011.28998. Hungarian.

PMID:
21224190
23.

Dimethylaminopyridine derivatives of lupane triterpenoids are potent disruptors of mitochondrial structure and function.

Holy J, Kolomitsyna O, Krasutsky D, Oliveira PJ, Perkins E, Krasutsky PA.

Bioorg Med Chem. 2010 Aug 15;18(16):6080-8. doi: 10.1016/j.bmc.2010.06.075. Epub 2010 Jul 1.

PMID:
20673631
24.

Differentiation of pluripotent stem cells on multiwalled carbon nanotubes.

Holy J, Perkins E, Yu X.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6022-5. doi: 10.1109/IEMBS.2009.5333699.

PMID:
19964415
25.

Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts.

Sardão VA, Oliveira PJ, Holy J, Oliveira CR, Wallace KB.

Cancer Chemother Pharmacol. 2009 Sep;64(4):811-27. doi: 10.1007/s00280-009-0932-x. Epub 2009 Jan 30.

PMID:
19184017
26.

Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells--nuclear vs. mitochondrial effects.

Serafim TL, Matos JA, Sardão VA, Pereira GC, Branco AF, Pereira SL, Parke D, Perkins EL, Moreno AJ, Holy J, Oliveira PJ.

Biochem Pharmacol. 2008 Dec 1;76(11):1459-75. doi: 10.1016/j.bcp.2008.07.013. Epub 2008 Jul 19.

PMID:
18692024
27.

Raman spectroscopy of aminated and ultrafine 1,3,5-triamino-2,4,6-trinitrobenzene and PBX 9502 as a function of pressing pressure.

Holy JA.

J Phys Chem B. 2008 Jun 26;112(25):7489-98. doi: 10.1021/jp801437w. Epub 2008 May 31.

PMID:
18512981
28.

Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets.

Sardão VA, Oliveira PJ, Holy J, Oliveira CR, Wallace KB.

Cell Biol Toxicol. 2009 Jun;25(3):227-43. doi: 10.1007/s10565-008-9070-1. Epub 2008 Apr 3.

PMID:
18386138
30.

Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions.

Pereira GC, Branco AF, Matos JA, Pereira SL, Parke D, Perkins EL, Serafim TL, Sardão VA, Santos MS, Moreno AJ, Holy J, Oliveira PJ.

J Pharmacol Exp Ther. 2007 Nov;323(2):636-49. Epub 2007 Aug 17.

PMID:
17704354
31.

Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line.

Serafim TL, Oliveira PJ, Sardao VA, Perkins E, Parke D, Holy J.

Cancer Chemother Pharmacol. 2008 May;61(6):1007-18. Epub 2007 Jul 28.

PMID:
17661039
32.

Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death.

Sardão VA, Oliveira PJ, Holy J, Oliveira CR, Wallace KB.

BMC Cell Biol. 2007 Mar 16;8:11.

33.
34.

Mycobacterium leprae infection of human Schwann cells depends on selective host kinases and pathogen-modulated endocytic pathways.

Alves L, de Mendonça Lima L, da Silva Maeda E, Carvalho L, Holy J, Sarno EN, Pessolani MC, Barker LP.

FEMS Microbiol Lett. 2004 Sep 15;238(2):429-37.

35.
36.

Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis.

Rolo AP, Palmeira CM, Holy JM, Wallace KB.

Toxicol Sci. 2004 May;79(1):196-204. Epub 2004 Feb 19.

PMID:
14976352
37.
38.

Intermediate filament proteins in echinoderm coelomocytes.

Holy J.

Comp Biochem Physiol B Biochem Mol Biol. 2000 Dec;127(4):491-504.

PMID:
11281266
40.

Imaging sea urchin fertilization.

Holy JM.

Methods Mol Biol. 1999;122:153-66. Review. No abstract available.

PMID:
10231790
41.

[The"aging" but still youthfully active UNICEF in 1997].

Holý J.

Cas Lek Cesk. 1998 Aug 31;137(17):537-8. Czech. No abstract available.

PMID:
9787508
43.

Confocal microscopic observation of cytoskeletal reorganizations in cultured shark rectal gland cells following treatment with hypotonic shock and high external K+.

Henson JH, Roesener CD, Gaetano CJ, Mendola RJ, Forrest JN Jr, Holy J, Kleinzeller A.

J Exp Zool. 1997 Dec 1;279(5):415-24.

PMID:
9392862
44.
45.

[The Ceská Diakonie Hospital in Prague].

Holý J.

Cas Lek Cesk. 1996 Nov 20;135(22):736-8. Czech. No abstract available.

PMID:
8998828
46.

[Was the world in 1995 really a better place for our children?].

Holý J.

Cas Lek Cesk. 1996 Jul 31;135(15):498. Czech. No abstract available.

PMID:
8925553
47.

Conserved expression of a B-type nuclear lamin in different tissues of the sea urchin.

Holy J.

Biochem Biophys Res Commun. 1996 May 15;222(2):531-6.

PMID:
8670239
48.

[Problems of poverty, population growth and the environment in relation to the Children's Fund of the United Nations].

Holý J.

Cas Lek Cesk. 1995 Apr 5;134(7):214-5. Czech. No abstract available.

PMID:
7758077
49.

Molecular characterization and expression patterns of a B-type nuclear lamin during sea urchin embryogenesis.

Holy J, Wessel G, Berg L, Gregg RG, Schatten G.

Dev Biol. 1995 Apr;168(2):464-78.

50.

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