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Items: 29


The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation.

Trommelen J, Holwerda AM, Nyakayiru J, Gorissen SHM, Rooyackers O, Burd NA, Boirie Y, van Loon LJC.

Am J Physiol Endocrinol Metab. 2019 Sep 1;317(3):E433-E434. doi: 10.1152/ajpendo.00155.2019. No abstract available.


Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial.

Fuchs CJ, Hermans WJH, Holwerda AM, Smeets JSJ, Senden JM, van Kranenburg J, Gijsen AP, Wodzig WKHW, Schierbeek H, Verdijk LB, van Loon LJC.

Am J Clin Nutr. 2019 Oct 1;110(4):862-872. doi: 10.1093/ajcn/nqz120.


Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men.

Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig WKWH, Verdijk LB, de Groot LCPGM, van Loon LJC.

Am J Physiol Endocrinol Metab. 2019 Sep 1;317(3):E473-E482. doi: 10.1152/ajpendo.00073.2019. Epub 2019 May 21.


One Week of Step Reduction Lowers Myofibrillar Protein Synthesis Rates in Young Men.

Shad BJ, Thompson JL, Holwerda AM, Stocks B, Elhassan YS, Philp A, VAN Loon LJC, Wallis GA.

Med Sci Sports Exerc. 2019 Oct;51(10):2125-2134. doi: 10.1249/MSS.0000000000002034.


The Impact of Pre-sleep Protein Ingestion on the Skeletal Muscle Adaptive Response to Exercise in Humans: An Update.

Snijders T, Trommelen J, Kouw IWK, Holwerda AM, Verdijk LB, van Loon LJC.

Front Nutr. 2019 Mar 6;6:17. doi: 10.3389/fnut.2019.00017. eCollection 2019. Review.


Dose-Dependent Increases in Whole-Body Net Protein Balance and Dietary Protein-Derived Amino Acid Incorporation into Myofibrillar Protein During Recovery from Resistance Exercise in Older Men.

Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig WKWH, Verdijk LB, van Loon LJC.

J Nutr. 2019 Feb 1;149(2):221-230. doi: 10.1093/jn/nxy263.


Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed rest.

Dirks ML, Smeets JSJ, Holwerda AM, Kouw IWK, Marzuca-Nassr GN, Gijsen AP, Holloway GP, Verdijk LB, van Loon LJC.

Am J Physiol Endocrinol Metab. 2019 Mar 1;316(3):E536-E545. doi: 10.1152/ajpendo.00378.2018. Epub 2019 Jan 15.


Protein Supplementation after Exercise and before Sleep Does Not Further Augment Muscle Mass and Strength Gains during Resistance Exercise Training in Active Older Men.

Holwerda AM, Overkamp M, Paulussen KJM, Smeets JSJ, van Kranenburg J, Backx EMP, Gijsen AP, Goessens JPB, Verdijk LB, van Loon LJC.

J Nutr. 2018 Nov 1;148(11):1723-1732. doi: 10.1093/jn/nxy169.


Skeletal muscle fiber characteristics in patients with chronic heart failure: impact of disease severity and relation with muscle oxygenation during exercise.

Niemeijer VM, Snijders T, Verdijk LB, van Kranenburg J, Groen BBL, Holwerda AM, Spee RF, Wijn PFF, van Loon LJC, Kemps HMC.

J Appl Physiol (1985). 2018 Aug 9. doi: 10.1152/japplphysiol.00057.2018. [Epub ahead of print]


Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle.

Holloway GP, Holwerda AM, Miotto PM, Dirks ML, Verdijk LB, van Loon LJC.

Cell Rep. 2018 Mar 13;22(11):2837-2848. doi: 10.1016/j.celrep.2018.02.069.


Daily resistance-type exercise stimulates muscle protein synthesis in vivo in young men.

Holwerda AM, Paulussen KJM, Overkamp M, Smeets JSJ, Gijsen AP, Goessens JPB, Verdijk LB, van Loon LJC.

J Appl Physiol (1985). 2018 Jan 1;124(1):66-75. doi: 10.1152/japplphysiol.00610.2017. Epub 2017 Sep 21.


Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial.

Kouw IW, Holwerda AM, Trommelen J, Kramer IF, Bastiaanse J, Halson SL, Wodzig WK, Verdijk LB, van Loon LJ.

J Nutr. 2017 Dec;147(12):2252-2261. doi: 10.3945/jn.117.254532. Epub 2017 Aug 30.


Presleep dietary protein-derived amino acids are incorporated in myofibrillar protein during postexercise overnight recovery.

Trommelen J, Kouw IWK, Holwerda AM, Snijders T, Halson SL, Rollo I, Verdijk LB, van Loon LJC.

Am J Physiol Endocrinol Metab. 2018 May 1;314(5):E457-E467. doi: 10.1152/ajpendo.00273.2016. Epub 2017 May 23.


Food ingestion in an upright sitting position increases postprandial amino acid availability when compared with food ingestion in a lying down position.

Holwerda AM, Lenaerts K, Bierau J, Wodzig WKWH, van Loon LJC.

Appl Physiol Nutr Metab. 2017 Jul;42(7):738-743. doi: 10.1139/apnm-2016-0522. Epub 2017 Feb 17.


Resistance Exercise Augments Postprandial Overnight Muscle Protein Synthesis Rates.

Trommelen J, Holwerda AM, Kouw IW, Langer H, Halson SL, Rollo I, Verdijk LB, VAN Loon LJ.

Med Sci Sports Exerc. 2016 Dec;48(12):2517-2525.


Physical Activity Performed in the Evening Increases the Overnight Muscle Protein Synthetic Response to Presleep Protein Ingestion in Older Men.

Holwerda AM, Kouw IW, Trommelen J, Halson SL, Wodzig WK, Verdijk LB, van Loon LJ.

J Nutr. 2016 Jul;146(7):1307-14. doi: 10.3945/jn.116.230086. Epub 2016 Jun 8.


What is the Optimal Amount of Protein to Support Post-Exercise Skeletal Muscle Reconditioning in the Older Adult?

Churchward-Venne TA, Holwerda AM, Phillips SM, van Loon LJ.

Sports Med. 2016 Sep;46(9):1205-12. doi: 10.1007/s40279-016-0504-2. Review.


Hsp25 and Hsp72 content in rat skeletal muscle following controlled shortening and lengthening contractions.

Holwerda AM, Locke M.

Appl Physiol Nutr Metab. 2014 Dec;39(12):1380-7. doi: 10.1139/apnm-2014-0118. Epub 2014 Aug 26.


Refining dietary protein recommendations for the athlete.

Holwerda AM, van Vliet S, Trommelen J.

J Physiol. 2013 Jun 15;591(12):2967-8. doi: 10.1113/jphysiol.2013.255927. No abstract available.


Low-load high volume resistance exercise stimulates muscle protein synthesis more than high-load low volume resistance exercise in young men.

Burd NA, West DW, Staples AW, Atherton PJ, Baker JM, Moore DR, Holwerda AM, Parise G, Rennie MJ, Baker SK, Phillips SM.

PLoS One. 2010 Aug 9;5(8):e12033. doi: 10.1371/journal.pone.0012033.


Effects of capsinoid ingestion on energy expenditure and lipid oxidation at rest and during exercise.

Josse AR, Sherriffs SS, Holwerda AM, Andrews R, Staples AW, Phillips SM.

Nutr Metab (Lond). 2010 Aug 3;7:65. doi: 10.1186/1743-7075-7-65.


Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men.

Burd NA, Holwerda AM, Selby KC, West DW, Staples AW, Cain NE, Cashaback JG, Potvin JR, Baker SK, Phillips SM.

J Physiol. 2010 Aug 15;588(Pt 16):3119-30. doi: 10.1113/jphysiol.2010.192856. Epub 2010 Jun 25.


Elevations in ostensibly anabolic hormones with resistance exercise enhance neither training-induced muscle hypertrophy nor strength of the elbow flexors.

West DW, Burd NA, Tang JE, Moore DR, Staples AW, Holwerda AM, Baker SK, Phillips SM.

J Appl Physiol (1985). 2010 Jan;108(1):60-7. doi: 10.1152/japplphysiol.01147.2009. Epub 2009 Nov 12.


Characterization of HLA-B57-restricted human immunodeficiency virus type 1 Gag- and RT-specific cytotoxic T lymphocyte responses.

Klein MR, van der Burg SH, Hovenkamp E, Holwerda AM, Drijfhout JW, Melief CJ, Miedema F.

J Gen Virol. 1998 Sep;79 ( Pt 9):2191-201.


HIV-1 reverse transcriptase-specific CTL against conserved epitopes do not protect against progression to AIDS.

van der Burg SH, Klein MR, Pontesilli O, Holwerda AM, Drijfhout JW, Kast WM, Miedema F, Melief CJ.

J Immunol. 1997 Oct 1;159(7):3648-54.


Gag-specific immune responses after immunization with p17/p24:Ty virus-like particles in HIV type 1-seropositive individuals.

Klein MR, Veenstra J, Holwerda AM, Roos MT, Gow I, Patou G, Coutinho RA, De Wolf F, Miedema F.

AIDS Res Hum Retroviruses. 1997 Mar 20;13(5):393-9.


Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics.

Klein MR, van Baalen CA, Holwerda AM, Kerkhof Garde SR, Bende RJ, Keet IP, Eeftinck-Schattenkerk JK, Osterhaus AD, Schuitemaker H, Miedema F.

J Exp Med. 1995 Apr 1;181(4):1365-72.

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