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Items: 49

1.

Structures of the intermediates of Kok's photosynthetic water oxidation clock.

Kern J, Chatterjee R, Young ID, Fuller FD, Lassalle L, Ibrahim M, Gul S, Fransson T, Brewster AS, Alonso-Mori R, Hussein R, Zhang M, Douthit L, de Lichtenberg C, Cheah MH, Shevela D, Wersig J, Seuffert I, Sokaras D, Pastor E, Weninger C, Kroll T, Sierra RG, Aller P, Butryn A, Orville AM, Liang M, Batyuk A, Koglin JE, Carbajo S, Boutet S, Moriarty NW, Holton JM, Dobbek H, Adams PD, Bergmann U, Sauter NK, Zouni A, Messinger J, Yano J, Yachandra VK.

Nature. 2018 Nov;563(7731):421-425. doi: 10.1038/s41586-018-0681-2. Epub 2018 Nov 7.

2.

Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.

Knott GJ, East-Seletsky A, Cofsky JC, Holton JM, Charles E, O'Connell MR, Doudna JA.

Nat Struct Mol Biol. 2017 Oct;24(10):825-833. doi: 10.1038/nsmb.3466. Epub 2017 Sep 11.

3.

Se-SAD serial femtosecond crystallography datasets from selenobiotinyl-streptavidin.

Yoon CH, DeMirci H, Sierra RG, Dao EH, Ahmadi R, Aksit F, Aquila AL, Batyuk A, Ciftci H, Guillet S, Hayes MJ, Hayes B, Lane TJ, Liang M, Lundström U, Koglin JE, Mgbam P, Rao Y, Rendahl T, Rodriguez E, Zhang L, Wakatsuki S, Boutet S, Holton JM, Hunter MS.

Sci Data. 2017 Apr 25;4:170055. doi: 10.1038/sdata.2017.55.

4.

Selenium single-wavelength anomalous diffraction de novo phasing using an X-ray-free electron laser.

Hunter MS, Yoon CH, DeMirci H, Sierra RG, Dao EH, Ahmadi R, Aksit F, Aquila AL, Ciftci H, Guillet S, Hayes MJ, Lane TJ, Liang M, Lundström U, Koglin JE, Mgbam P, Rao Y, Zhang L, Wakatsuki S, Holton JM, Boutet S.

Nat Commun. 2016 Nov 4;7:13388. doi: 10.1038/ncomms13388.

5.

Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1 / SNARE complex.

Lyubimov AY, Uervirojnangkoorn M, Zeldin OB, Zhou Q, Zhao M, Brewster AS, Michels-Clark T, Holton JM, Sauter NK, Weis WI, Brunger AT.

Elife. 2016 Oct 12;5. pii: e18740. doi: 10.7554/eLife.18740.

6.

Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.

Keedy DA, Kenner LR, Warkentin M, Woldeyes RA, Hopkins JB, Thompson MC, Brewster AS, Van Benschoten AH, Baxter EL, Uervirojnangkoorn M, McPhillips SE, Song J, Alonso-Mori R, Holton JM, Weis WI, Brunger AT, Soltis SM, Lemke H, Gonzalez A, Sauter NK, Cohen AE, van den Bedem H, Thorne RE, Fraser JS.

Elife. 2015 Sep 30;4. pii: e07574. doi: 10.7554/eLife.07574.

7.

Macromolecular X-ray structure determination using weak, single-wavelength anomalous data.

Bunkóczi G, McCoy AJ, Echols N, Grosse-Kunstleve RW, Adams PD, Holton JM, Read RJ, Terwilliger TC.

Nat Methods. 2015 Feb;12(2):127-30. doi: 10.1038/nmeth.3212. Epub 2014 Dec 22.

8.

Goniometer-based femtosecond crystallography with X-ray free electron lasers.

Cohen AE, Soltis SM, González A, Aguila L, Alonso-Mori R, Barnes CO, Baxter EL, Brehmer W, Brewster AS, Brunger AT, Calero G, Chang JF, Chollet M, Ehrensberger P, Eriksson TL, Feng Y, Hattne J, Hedman B, Hollenbeck M, Holton JM, Keable S, Kobilka BK, Kovaleva EG, Kruse AC, Lemke HT, Lin G, Lyubimov AY, Manglik A, Mathews II, McPhillips SE, Nelson S, Peters JW, Sauter NK, Smith CA, Song J, Stevenson HP, Tsai Y, Uervirojnangkoorn M, Vinetsky V, Wakatsuki S, Weis WI, Zadvornyy OA, Zeldin OB, Zhu D, Hodgson KO.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17122-7. doi: 10.1073/pnas.1418733111. Epub 2014 Oct 31.

9.

The R-factor gap in macromolecular crystallography: an untapped potential for insights on accurate structures.

Holton JM, Classen S, Frankel KA, Tainer JA.

FEBS J. 2014 Sep;281(18):4046-60. doi: 10.1111/febs.12922. Epub 2014 Sep 17.

10.

Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC.

Mavrici D, Marakalala MJ, Holton JM, Prigozhin DM, Gee CL, Zhang YJ, Rubin EJ, Alber T.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8037-42. doi: 10.1073/pnas.1321812111. Epub 2014 May 19.

11.

Protein structural ensembles are revealed by redefining X-ray electron density noise.

Lang PT, Holton JM, Fraser JS, Alber T.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):237-42. doi: 10.1073/pnas.1302823110. Epub 2013 Dec 20.

12.

Predicting the X-ray lifetime of protein crystals.

Zeldin OB, Brockhauser S, Bremridge J, Holton JM, Garman EF.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20551-6. doi: 10.1073/pnas.1315879110. Epub 2013 Dec 2.

13.

Crystallographic data processing for free-electron laser sources.

White TA, Barty A, Stellato F, Holton JM, Kirian RA, Zatsepin NA, Chapman HN.

Acta Crystallogr D Biol Crystallogr. 2013 Jul;69(Pt 7):1231-40. doi: 10.1107/S0907444913013620. Epub 2013 Jun 15.

14.

Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source.

Classen S, Hura GL, Holton JM, Rambo RP, Rodic I, McGuire PJ, Dyer K, Hammel M, Meigs G, Frankel KA, Tainer JA.

J Appl Crystallogr. 2013 Feb 1;46(Pt 1):1-13. Epub 2013 Jan 17.

15.

The point-spread function of fiber-coupled area detectors.

Holton JM, Nielsen C, Frankel KA.

J Synchrotron Radiat. 2012 Nov;19(Pt 6):1006-11. doi: 10.1107/S0909049512035571. Epub 2012 Sep 5.

16.

Molecular analysis and modeling of inactivation of human CYP2D6 by four mechanism based inactivators.

Livezey M, Nagy LD, Diffenderfer LE, Arthur EJ, Hsi DJ, Holton JM, Furge LL.

Drug Metab Lett. 2012 Mar;6(1):7-14.

17.

Time-resolved protein nanocrystallography using an X-ray free-electron laser.

Aquila A, Hunter MS, Doak RB, Kirian RA, Fromme P, White TA, Andreasson J, Arnlund D, Bajt S, Barends TR, Barthelmess M, Bogan MJ, Bostedt C, Bottin H, Bozek JD, Caleman C, Coppola N, Davidsson J, DePonte DP, Elser V, Epp SW, Erk B, Fleckenstein H, Foucar L, Frank M, Fromme R, Graafsma H, Grotjohann I, Gumprecht L, Hajdu J, Hampton CY, Hartmann A, Hartmann R, Hau-Riege S, Hauser G, Hirsemann H, Holl P, Holton JM, Hömke A, Johansson L, Kimmel N, Kassemeyer S, Krasniqi F, Kühnel KU, Liang M, Lomb L, Malmerberg E, Marchesini S, Martin AV, Maia FR, Messerschmidt M, Nass K, Reich C, Neutze R, Rolles D, Rudek B, Rudenko A, Schlichting I, Schmidt C, Schmidt KE, Schulz J, Seibert MM, Shoeman RL, Sierra R, Soltau H, Starodub D, Stellato F, Stern S, Strüder L, Timneanu N, Ullrich J, Wang X, Williams GJ, Weidenspointner G, Weierstall U, Wunderer C, Barty A, Spence JC, Chapman HN.

Opt Express. 2012 Jan 30;20(3):2706-16. doi: 10.1364/OE.20.002706.

18.

Radiation damage in protein serial femtosecond crystallography using an x-ray free-electron laser.

Lomb L, Barends TR, Kassemeyer S, Aquila A, Epp SW, Erk B, Foucar L, Hartmann R, Rudek B, Rolles D, Rudenko A, Shoeman RL, Andreasson J, Bajt S, Barthelmess M, Barty A, Bogan MJ, Bostedt C, Bozek JD, Caleman C, Coffee R, Coppola N, Deponte DP, Doak RB, Ekeberg T, Fleckenstein H, Fromme P, Gebhardt M, Graafsma H, Gumprecht L, Hampton CY, Hartmann A, Hauser G, Hirsemann H, Holl P, Holton JM, Hunter MS, Kabsch W, Kimmel N, Kirian RA, Liang M, Maia FR, Meinhart A, Marchesini S, Martin AV, Nass K, Reich C, Schulz J, Seibert MM, Sierra R, Soltau H, Spence JC, Steinbrener J, Stellato F, Stern S, Timneanu N, Wang X, Weidenspointner G, Weierstall U, White TA, Wunderer C, Chapman HN, Ullrich J, Strüder L, Schlichting I.

Phys Rev B Condens Matter Mater Phys. 2011 Dec 1;84(21):214111.

19.

Accessing protein conformational ensembles using room-temperature X-ray crystallography.

Fraser JS, van den Bedem H, Samelson AJ, Lang PT, Holton JM, Echols N, Alber T.

Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16247-52. doi: 10.1073/pnas.1111325108. Epub 2011 Sep 14.

20.

Hyaloperonospora arabidopsidis ATR1 effector is a repeat protein with distributed recognition surfaces.

Chou S, Krasileva KV, Holton JM, Steinbrenner AD, Alber T, Staskawicz BJ.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13323-8. doi: 10.1073/pnas.1109791108. Epub 2011 Jul 25.

21.

Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals.

Kirian RA, White TA, Holton JM, Chapman HN, Fromme P, Barty A, Lomb L, Aquila A, Maia FR, Martin AV, Fromme R, Wang X, Hunter MS, Schmidt KE, Spence JC.

Acta Crystallogr A. 2011 Mar;67(Pt 2):131-40. doi: 10.1107/S0108767310050981. Epub 2011 Feb 16.

22.

Femtosecond X-ray protein nanocrystallography.

Chapman HN, Fromme P, Barty A, White TA, Kirian RA, Aquila A, Hunter MS, Schulz J, DePonte DP, Weierstall U, Doak RB, Maia FR, Martin AV, Schlichting I, Lomb L, Coppola N, Shoeman RL, Epp SW, Hartmann R, Rolles D, Rudenko A, Foucar L, Kimmel N, Weidenspointner G, Holl P, Liang M, Barthelmess M, Caleman C, Boutet S, Bogan MJ, Krzywinski J, Bostedt C, Bajt S, Gumprecht L, Rudek B, Erk B, Schmidt C, Hömke A, Reich C, Pietschner D, Strüder L, Hauser G, Gorke H, Ullrich J, Herrmann S, Schaller G, Schopper F, Soltau H, Kühnel KU, Messerschmidt M, Bozek JD, Hau-Riege SP, Frank M, Hampton CY, Sierra RG, Starodub D, Williams GJ, Hajdu J, Timneanu N, Seibert MM, Andreasson J, Rocker A, Jönsson O, Svenda M, Stern S, Nass K, Andritschke R, Schröter CD, Krasniqi F, Bott M, Schmidt KE, Wang X, Grotjohann I, Holton JM, Barends TR, Neutze R, Marchesini S, Fromme R, Schorb S, Rupp D, Adolph M, Gorkhover T, Andersson I, Hirsemann H, Potdevin G, Graafsma H, Nilsson B, Spence JC.

Nature. 2011 Feb 3;470(7332):73-7. doi: 10.1038/nature09750.

23.

Automated electron-density sampling reveals widespread conformational polymorphism in proteins.

Lang PT, Ng HL, Fraser JS, Corn JE, Echols N, Sales M, Holton JM, Alber T.

Protein Sci. 2010 Jul;19(7):1420-31. doi: 10.1002/pro.423.

24.

The minimum crystal size needed for a complete diffraction data set.

Holton JM, Frankel KA.

Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):393-408. doi: 10.1107/S0907444910007262. Epub 2010 Mar 24.

25.

An assessment of the resolution limitation due to radiation-damage in x-ray diffraction microscopy.

Howells MR, Beetz T, Chapman HN, Cui C, Holton JM, Jacobsen CJ, Kirz J, Lima E, Marchesini S, Miao H, Sayre D, Shapiro DA, Spence JC, Starodub D.

J Electron Spectros Relat Phenomena. 2009 Mar 1;170(1-3):4-12.

26.

Determination of X-ray flux using silicon pin diodes.

Owen RL, Holton JM, Schulze-Briese C, Garman EF.

J Synchrotron Radiat. 2009 Mar;16(Pt 2):143-51. doi: 10.1107/S0909049508040429. Epub 2009 Feb 25.

27.

A beginner's guide to radiation damage.

Holton JM.

J Synchrotron Radiat. 2009 Mar;16(Pt 2):133-42. doi: 10.1107/S0909049509004361. Epub 2009 Feb 25. Review.

28.

Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75.

Berndsen CE, Tsubota T, Lindner SE, Lee S, Holton JM, Kaufman PD, Keck JL, Denu JM.

Nat Struct Mol Biol. 2008 Sep;15(9):948-56.

29.

Structure of a designed, right-handed coiled-coil tetramer containing all biological amino acids.

Sales M, Plecs JJ, Holton JM, Alber T.

Protein Sci. 2007 Oct;16(10):2224-32. Epub 2007 Aug 31.

30.

A steric block in translation caused by the antibiotic spectinomycin.

Borovinskaya MA, Shoji S, Holton JM, Fredrick K, Cate JHD.

ACS Chem Biol. 2007 Aug 17;2(8):545-552. doi: 10.1021/cb700100n. Epub 2007 Aug 10.

31.

Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.

Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS, Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH.

Nat Struct Mol Biol. 2007 Aug;14(8):727-32. Epub 2007 Jul 29.

PMID:
17660832
32.

Structural insight into KCNQ (Kv7) channel assembly and channelopathy.

Howard RJ, Clark KA, Holton JM, Minor DL Jr.

Neuron. 2007 Mar 1;53(5):663-75.

33.

Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.

Huang DT, Hunt HW, Zhuang M, Ohi MD, Holton JM, Schulman BA.

Nature. 2007 Jan 25;445(7126):394-8. Epub 2007 Jan 14.

34.

XANES measurements of the rate of radiation damage to selenomethionine side chains.

Holton JM.

J Synchrotron Radiat. 2007 Jan;14(Pt 1):51-72. Epub 2006 Dec 15.

35.

Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis.

Rho BS, Hung LW, Holton JM, Vigil D, Kim SI, Park MS, Terwilliger TC, Pédelacq JD.

J Mol Biol. 2006 Sep 1;361(5):850-63. Epub 2006 Jun 27.

PMID:
16884737
36.

Structures of the bacterial ribosome at 3.5 A resolution.

Schuwirth BS, Borovinskaya MA, Hau CW, Zhang W, Vila-Sanjurjo A, Holton JM, Cate JH.

Science. 2005 Nov 4;310(5749):827-34.

37.

Structural and mechanistic studies of VPS4 proteins.

Scott A, Chung HY, Gonciarz-Swiatek M, Hill GC, Whitby FG, Gaspar J, Holton JM, Viswanathan R, Ghaffarian S, Hill CP, Sundquist WI.

EMBO J. 2005 Oct 19;24(20):3658-69. Epub 2005 Sep 29.

38.

Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.

Huang DT, Paydar A, Zhuang M, Waddell MB, Holton JM, Schulman BA.

Mol Cell. 2005 Feb 4;17(3):341-50.

39.
40.

Suite of three protein crystallography beamlines with single superconducting bend magnet as the source.

MacDowell AA, Celestre RS, Howells M, McKinney W, Krupnick J, Cambie D, Domning EE, Duarte RM, Kelez N, Plate DW, Cork CW, Earnest TN, Dickert J, Meigs G, Ralston C, Holton JM, Alber T, Berger JM, Agard DA, Padmore HA.

J Synchrotron Radiat. 2004 Nov 1;11(Pt 6):447-55. Epub 2004 Oct 22.

PMID:
15496731
41.

A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.

Huang DT, Miller DW, Mathew R, Cassell R, Holton JM, Roussel MF, Schulman BA.

Nat Struct Mol Biol. 2004 Oct;11(10):927-35. Epub 2004 Sep 7.

42.

Ubiquitin recognition by the human TSG101 protein.

Sundquist WI, Schubert HL, Kelly BN, Hill GC, Holton JM, Hill CP.

Mol Cell. 2004 Mar 26;13(6):783-9.

43.

The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.

Walden H, Podgorski MS, Huang DT, Miller DW, Howard RJ, Minor DL Jr, Holton JM, Schulman BA.

Mol Cell. 2003 Dec;12(6):1427-37.

44.

Structure of melanoma inhibitory activity protein, a member of a recently identified family of secreted proteins.

Lougheed JC, Holton JM, Alber T, Bazan JF, Handel TM.

Proc Natl Acad Sci U S A. 2001 May 8;98(10):5515-20. Epub 2001 May 1.

45.

Crystallographic analysis of CD40 recognition and signaling by human TRAF2.

McWhirter SM, Pullen SS, Holton JM, Crute JJ, Kehry MR, Alber T.

Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8408-13.

46.

Circular dichroism determination of class I MHC-peptide equilibrium dissociation constants.

Morgan CS, Holton JM, Olafson BD, Bjorkman PJ, Mayo SL.

Protein Sci. 1997 Aug;6(8):1771-3.

47.

Growth of Candida species in liquid culture medium for Trichomonas vaginalis.

Erdman YJ, Holton JM, Becker A.

Br J Vener Dis. 1984 Feb;60(1):39-41.

48.

The effect of contrast media on the growth of bacteria.

Dawson P, Becker A, Holton JM.

Br J Radiol. 1983 Nov;56(671):809-15.

PMID:
6354344
49.

A case of anaerobic streptococcal osteomyelitis following a simple fracture of a rib.

Holton JM.

Injury. 1971 Jan;2(3):245-6. No abstract available.

PMID:
5118786

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