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Items: 1 to 50 of 53

1.

Ultralow dose fentanyl prevents development of chronic neuropathic pain in rats.

Wala EP, Holtman JR, Sloan PA.

J Opioid Manag. 2013 Mar-Apr;9(2):85-96. doi: 10.5055/jom.2013.0150.

PMID:
23709318
2.

Opioid-induced hyperalgesia and burn pain.

Holtman JR Jr, Jellish WS.

J Burn Care Res. 2012 Nov-Dec;33(6):692-701. doi: 10.1097/BCR.0b013e31825adcb0. Review.

PMID:
23143613
3.

Novel small molecule α9α10 nicotinic receptor antagonist prevents and reverses chemotherapy-evoked neuropathic pain in rats.

Wala EP, Crooks PA, McIntosh JM, Holtman JR Jr.

Anesth Analg. 2012 Sep;115(3):713-20. doi: 10.1213/ANE.0b013e31825a3c72. Epub 2012 May 18.

4.

Effect of prior treatment with ultra-low-dose morphine on opioid- and nerve injury-induced hyperalgesia in rats.

Wala EP, Sloan PA, Holtman JR Jr.

J Opioid Manag. 2011 Sep-Oct;7(5):377-89.

PMID:
22165037
5.

The novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic.

Holtman JR, Dwoskin LP, Dowell C, Wala EP, Zhang Z, Crooks PA, McIntosh JM.

Eur J Pharmacol. 2011 Nov 30;670(2-3):500-8. doi: 10.1016/j.ejphar.2011.08.053. Epub 2011 Sep 17.

6.

Priapism following a lumbar sympathetic nerve block.

Sniderman M, Raghavendra M, Holtman JR Jr.

Pain Med. 2011 Jul;12(7):1046-8. doi: 10.1111/j.1526-4637.2011.01145.x. Epub 2011 Jun 13.

PMID:
21668749
7.

Discovery of non-peptide, small molecule antagonists of α9α10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain.

Zheng G, Zhang Z, Dowell C, Wala E, Dwoskin LP, Holtman JR, McIntosh JM, Crooks PA.

Bioorg Med Chem Lett. 2011 Apr 15;21(8):2476-9. doi: 10.1016/j.bmcl.2011.02.043. Epub 2011 Feb 23.

8.

Buprenorphine-induced hyperalgesia in the rat.

Wala EP, Holtman JR Jr.

Eur J Pharmacol. 2011 Jan 25;651(1-3):89-95. doi: 10.1016/j.ejphar.2010.10.083. Epub 2010 Nov 30.

PMID:
21114985
9.

Antinociceptive effects and toxicity of morphine-6-O-sulfate sodium salt in rat models of pain.

Holtman JR Jr, Crooks PA, Johnson-Hardy J, Wala EP.

Eur J Pharmacol. 2010 Dec 1;648(1-3):87-94. doi: 10.1016/j.ejphar.2010.08.034. Epub 2010 Sep 7.

PMID:
20828549
10.

The analgesic and toxic effects of nornicotine enantiomers alone and in interaction with morphine in rodent models of acute and persistent pain.

Holtman JR Jr, Crooks PA, Johnson-Hardy JK, Wala EP.

Pharmacol Biochem Behav. 2010 Jan;94(3):352-62. doi: 10.1016/j.pbb.2009.09.017. Epub 2009 Oct 2.

11.

The relative abuse liability of oral oxycodone, hydrocodone and hydromorphone assessed in prescription opioid abusers.

Walsh SL, Nuzzo PA, Lofwall MR, Holtman JR Jr.

Drug Alcohol Depend. 2008 Dec 1;98(3):191-202. doi: 10.1016/j.drugalcdep.2008.05.007. Epub 2008 Jul 7.

12.

Effects of norketamine enantiomers in rodent models of persistent pain.

Holtman JR Jr, Crooks PA, Johnson-Hardy JK, Hojomat M, Kleven M, Wala EP.

Pharmacol Biochem Behav. 2008 Oct;90(4):676-85. doi: 10.1016/j.pbb.2008.05.011.

PMID:
18586315
13.

Interaction between morphine and norketamine enantiomers in rodent models of nociception.

Holtman JR Jr, Crooks PA, Johnson-Hardy J, Wala EP.

Pharmacol Biochem Behav. 2008 Oct;90(4):769-77. doi: 10.1016/j.pbb.2008.05.019.

PMID:
18582492
14.

Characterization of the antinociceptive and pronociceptive effects of methadone in rats.

Holtman JR Jr, Wala EP.

Anesthesiology. 2007 Mar;106(3):563-71.

PMID:
17325516
15.

Characterization of the antinociceptive effect of oxycodone in male and female rats.

Holtman JR Jr, Wala EP.

Pharmacol Biochem Behav. 2006 Jan;83(1):100-8. Epub 2006 Jan 24.

PMID:
16434089
16.

Characterization of morphine-induced hyperalgesia in male and female rats.

Holtman JR Jr, Wala EP.

Pain. 2005 Mar;114(1-2):62-70.

PMID:
15733632
17.

Morphine tolerance in male and female rats.

Holtman JR Jr, Sloan JW, Wala EP.

Pharmacol Biochem Behav. 2004 Mar;77(3):517-23.

PMID:
15006462
18.

Sex-related differences in the enhancement of morphine antinociception by NMDA receptor antagonists in rats.

Holtman JR Jr, Jing X, Wala EP.

Pharmacol Biochem Behav. 2003 Sep;76(2):285-93.

PMID:
14592680
19.

The effects of flumazenil on the antinociceptive actions of morphine in rats.

Holtman JR Jr, Jing X, Sloan JW, Wala EP.

Receptors Channels. 2003;9(5):325-8.

PMID:
14527876
20.

Modification of morphine analgesia and tolerance by flumazenil in male and female rats.

Holtman JR Jr, Sloan JW, Jing X, Wala EP.

Eur J Pharmacol. 2003 Jun 6;470(3):149-56.

PMID:
12798952
21.

The effects of diazepam dependence and withdrawal on morphine-induced antinociception and changes in locomotion in male and female rats.

Wala EP, Sloan JW, Jing X, Holtman JR.

Pharmacol Biochem Behav. 2001 Jul-Aug;69(3-4):475-84.

PMID:
11509207
22.

The pharmacodynamics of PK 11195 in diazepam-dependent male and female rats.

Sloan JW, Wala EP, Jing X, Holtman JR Jr.

Pharmacol Biochem Behav. 2000 Aug;66(4):751-64.

PMID:
10973513
23.

Precipitated withdrawal in the substantia nigra in diazepam-dependent female rats.

Wala EP, Sloan JW, Jing X, Holtman JR Jr.

Pharmacol Biochem Behav. 1999 Dec;64(4):857-68.

PMID:
10593210
24.

Diazepam-treated female rats: flumazenil- and PK 11195-induced withdrawal in the hippocampus CA1.

Sloan JW, Wala E, Jing X, Holtman JR Jr, Milliken B.

Pharmacol Biochem Behav. 1998 Sep;61(1):121-30.

PMID:
9715814
25.

Effect of activation of 5-HT1A receptors at the ventral medulla on phrenic nerve activity.

Holtman JR Jr, King KA.

Eur J Pharmacol. 1994 Mar 3;253(3):307-10.

PMID:
8200427
26.

Substance P immunoreactive projections to the ventral respiratory group in the rat.

Holtman JR Jr, Speck DF.

Peptides. 1994;15(5):803-8.

PMID:
7527143
27.

Analgesic actions of local anesthetics and cobalt chloride in the rat brain stem.

Hamann SR, Holtman JR, Martin WR.

Pharmacol Biochem Behav. 1992 Nov;43(3):925-7.

PMID:
1448487
28.

Immunohistochemistry of central respiratory neurotransmitters.

Holtman JR Jr.

Am J Physiol. 1991 Jun;260(6 Pt 1):L374-80. Review.

PMID:
1711783
29.

Ultrastructural evidence for serotonin-immunoreactive terminals contacting phrenic motoneurons in the cat.

Holtman JR Jr, Vascik DS, Maley BE.

Exp Neurol. 1990 Sep;109(3):269-72.

PMID:
2209771
31.

Origin of serotonin-containing projections to the ventral respiratory group in the rat.

Holtman JR Jr, Marion LJ, Speck DF.

Neuroscience. 1990;37(2):541-52.

PMID:
2133358
32.

Effect of an alkylating analog of prazosin on alpha-1 adrenoceptor subtypes and arterial blood pressure.

Piascik MT, Butler BT, Kusiak JW, Pitha J, Holtman JR Jr.

J Pharmacol Exp Ther. 1989 Dec;251(3):878-83.

PMID:
2574745
33.
34.
35.

Regulation of respiratory motor outflow to the larynx and diaphragm by GABA receptors.

Holtman JR Jr, King KA.

Eur J Pharmacol. 1988 Nov 1;156(2):181-7.

PMID:
2853672
37.
38.
39.

Central respiratory stimulation produced by thyrotropin-releasing hormone in the cat.

Holtman JR Jr, Buller AL, Hamosh P, Gillis RA.

Peptides. 1986 Mar-Apr;7(2):207-12.

PMID:
3090523
40.

Effect of electrical and chemical stimulation of the raphe obscurus on phrenic nerve activity in the cat.

Holtman JR Jr, Anastasi NC, Norman WP, Dretchen KL.

Brain Res. 1986 Jan 8;362(2):214-20.

PMID:
2867815
41.

Comparative cardiorespiratory effects produced by taurine and glycine applied to the ventral surface of the medulla.

Gatti PJ, Souza JD, Namath IJ, Da Silva AM, Holtman JR Jr, Gillis R.

J Pharmacol Exp Ther. 1985 Dec;235(3):820-8.

PMID:
3001279
42.

Evidence for 5-hydroxytryptamine, substance P, and thyrotropin-releasing hormone in neurons innervating the phrenic motor nucleus.

Holtman JR Jr, Norman WP, Skirboll L, Dretchen KL, Cuello C, Visser TJ, Hökfelt T, Gillis RA.

J Neurosci. 1984 Apr;4(4):1064-71.

43.

Central nervous system site of action of capsaicin-induced cardiovascular changes in the cat.

Quest JA, Dias-Souza J, Norman WP, Holtman JR Jr, Gillis RA.

J Pharmacol Exp Ther. 1984 Mar;228(3):719-24.

PMID:
6707921
44.

Projections from the raphe nuclei to the phrenic motor nucleus in the cat.

Holtman JR Jr, Norman WP, Gillis RA.

Neurosci Lett. 1984 Jan 27;44(1):105-11.

PMID:
6717845
45.

Increased release of [3H]acetylcholine in vitro from the mouse hippocampus by a convulsant barbiturate.

Holtman JR Jr, Richter JA.

Neuropharmacology. 1983 Sep;22(9):1101-8.

PMID:
6138729
47.

Central respiratory stimulant effect of bombesin in the cat.

Holtman JR Jr, Jensen RT, Buller A, Hamosh P, Taveira Da Silva AM, Gillis RA.

Eur J Pharmacol. 1983 Jun 17;90(4):449-51.

PMID:
6884433
48.

Respiratory depression produced by centrally administered taurine in the cat.

Holtman JR Jr, Buller AL, Taveira Da Silva AM, Hamosh P, Gillis RA.

Life Sci. 1983 May 16;32(20):2313-20.

PMID:
6843296
49.

Effects of convulsant barbiturates on endogenous acetylcholine release and sodium-dependent high affinity choline uptake.

Holtman JR Jr, Richter JA.

J Pharmacol Exp Ther. 1983 Feb;224(2):398-403. No abstract available.

PMID:
6130145
50.

Respiratory depression produced by glycine injected into the cisterna magna of cats.

Holtman JR Jr, Buller AL, Hamosh P, Da Silva AM, Gillis RA.

Neuropharmacology. 1982 Nov;21(11):1223-5.

PMID:
7177349

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