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Items: 1 to 50 of 171

1.

The potential of adenoviral vaccine vectors with altered antigen presentation capabilities.

Neukirch L, Fougeroux C, Andersson AC, Holst PJ.

Expert Rev Vaccines. 2020 Jan 23:1-17. doi: 10.1080/14760584.2020.1711054. [Epub ahead of print]

PMID:
31889453
2.

Virus-like vaccines against HIV/SIV synergize with a subdominant antigen T cell vaccine.

Schwerdtfeger M, Andersson AC, Neukirch L, Holst PJ.

J Transl Med. 2019 May 24;17(1):175. doi: 10.1186/s12967-019-1924-1.

3.

CD8+ T cells induced by adenovirus-vectored vaccine are capable of preventing establishment of latent murine γ-herpesvirus 68 infection.

Boilesen DR, Ragonnaud E, Laursen H, Andersson AC, Tolver A, Spiess K, Holst PJ.

Vaccine. 2019 May 16;37(22):2952-2959. doi: 10.1016/j.vaccine.2019.04.034. Epub 2019 Apr 18.

PMID:
31006497
4.

Adenovirus based virus-like-vaccines targeting endogenous retroviruses can eliminate growing colorectal cancers in mice.

Neukirch L, Nielsen TK, Laursen H, Daradoumis J, Thirion C, Holst PJ.

Oncotarget. 2019 Feb 15;10(14):1458-1472. doi: 10.18632/oncotarget.26680. eCollection 2019 Feb 15.

5.

Modified MHC Class II-Associated Invariant Chain Induces Increased Antibody Responses against Plasmodium falciparum Antigens after Adenoviral Vaccination.

Fougeroux C, Turner L, Bojesen AM, Lavstsen T, Holst PJ.

J Immunol. 2019 Apr 15;202(8):2320-2331. doi: 10.4049/jimmunol.1801210. Epub 2019 Mar 4.

6.

Development of a Symmetric Echo-Planar Spectroscopy Imaging Framework for Hyperpolarized 13C Imaging in a Clinical PET/MR Scanner.

Eldirdiri A, Posse S, Hanson LG, Hansen RB, Holst P, Schøier C, Kristensen AT, Johannesen HH, Kjaer A, Hansen AE, Ardenkjaer-Larsen JH.

Tomography. 2018 Sep;4(3):110-122. doi: 10.18383/j.tom.2018.00006.

7.

Replication deficient human adenovirus vector serotype 19a/64: Immunogenicity in mice and female cynomolgus macaques.

Ragonnaud E, Schroedel S, Mariya S, Iskandriati D, Pamungkas J, Fougeroux C, Daradoumis J, Thomsen AR, Neukirch L, Ruzsics Z, Salomon M, Thirion C, Holst PJ.

Vaccine. 2018 Oct 1;36(41):6212-6222. doi: 10.1016/j.vaccine.2018.07.075. Epub 2018 Sep 3.

PMID:
30190120
8.

Combined hyperpolarized 13C-pyruvate MRS and 18F-FDG PET (hyperPET) estimates of glycolysis in canine cancer patients.

Hansen AE, Gutte H, Holst P, Johannesen HH, Rahbek S, Clemmensen AE, Larsen MME, Schøier C, Ardenkjaer-Larsen J, Klausen TL, Kristensen AT, Kjaer A.

Eur J Radiol. 2018 Jun;103:6-12. doi: 10.1016/j.ejrad.2018.02.028. Epub 2018 Feb 25.

9.

EBI2 in splenic and local immune responses and in autoimmunity.

Barington L, Wanke F, Niss Arfelt K, Holst PJ, Kurschus FC, Rosenkilde MM.

J Leukoc Biol. 2018 Aug;104(2):313-322. doi: 10.1002/JLB.2VMR1217-510R. Epub 2018 May 9. Review.

PMID:
29741800
10.

Virus-Like-Vaccines against HIV.

Andersson AC, Schwerdtfeger M, Holst PJ.

Vaccines (Basel). 2018 Feb 11;6(1). pii: E10. doi: 10.3390/vaccines6010010. Review.

11.

In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae.

Antenucci F, Fougeroux C, Deeney A, Ørskov C, Rycroft A, Holst PJ, Bojesen AM.

Vet Res. 2018 Jan 9;49(1):4. doi: 10.1186/s13567-017-0502-x.

12.

Identification and characterization of serovar-independent immunogens in Actinobacillus pleuropneumoniae.

Antenucci F, Fougeroux C, Bossé JT, Magnowska Z, Roesch C, Langford P, Holst PJ, Bojesen AM.

Vet Res. 2017 Nov 9;48(1):74. doi: 10.1186/s13567-017-0479-5.

13.

Future Prospects for the Development of Cost-Effective Adenovirus Vaccines.

Fougeroux C, Holst PJ.

Int J Mol Sci. 2017 Mar 23;18(4). pii: E686. doi: 10.3390/ijms18040686. Review.

14.

Effect of Skull Type on the Relative Size of Cerebral Cortex and Lateral Ventricles in Dogs.

Pilegaard AM, Berendt M, Holst P, Møller A, McEvoy FJ.

Front Vet Sci. 2017 Mar 16;4:30. doi: 10.3389/fvets.2017.00030. eCollection 2017.

15.

Future Prospects for the Development of Cost-Effective Adenovirus Vaccines.

Fougeroux C, Holst PJ.

Int J Mol Sci. 2017 Mar 23;18(3). pii: E686. doi: 10.3390/ijms18030686. Review.

16.

Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication.

Xu H, Andersson AM, Ragonnaud E, Boilesen D, Tolver A, Jensen BAH, Blanchard JL, Nicosia A, Folgori A, Colloca S, Cortese R, Thomsen AR, Christensen JP, Veazey RS, Holst PJ.

EBioMedicine. 2017 Apr;18:204-215. doi: 10.1016/j.ebiom.2017.03.003. Epub 2017 Mar 8.

17.

Therapeutic Vaccine Against Primate Papillomavirus Infections of the Cervix.

Ragonnaud E, Andersson AC, Mariya S, Pedersen AG, Burk RD, Folgori A, Colloca S, Cortese R, Nicosia A, Pamungkas J, Iskandriati D, Holst PJ.

J Immunother. 2017 Feb/Mar;40(2):51-61. doi: 10.1097/CJI.0000000000000153.

PMID:
28166180
18.

Novel adenovirus encoded virus-like particles displaying the placental malaria associated VAR2CSA antigen.

Andersson AC, Resende M, Salanti A, Nielsen MA, Holst PJ.

Vaccine. 2017 Feb 22;35(8):1140-1147. doi: 10.1016/j.vaccine.2017.01.016. Epub 2017 Jan 25.

PMID:
28131394
19.

Breadth of T Cell Responses After Immunization with Adenovirus Vectors Encoding Ancestral Antigens or Polyvalent Papillomavirus Antigens.

Ragonnaud E, Pedersen AG, Holst PJ.

Scand J Immunol. 2017 Mar;85(3):182-190. doi: 10.1111/sji.12522.

20.

EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies.

Niss Arfelt K, Barington L, Benned-Jensen T, Kubale V, Kovalchuk AL, Daugvilaite V, Christensen JP, Thomsen AR, Egerod KL, Bassi MR, Spiess K, Schwartz TW, Wang H, Morse HC 3rd, Holst PJ, Rosenkilde MM.

Blood. 2017 Feb 16;129(7):866-878. doi: 10.1182/blood-2016-02-697185. Epub 2016 Dec 21.

21.
22.

Early life vaccination: Generation of adult-quality memory CD8+ T cells in infant mice using non-replicating adenoviral vectors.

Nazerai L, Bassi MR, Uddback IE, Holst PJ, Christensen JP, Thomsen AR.

Sci Rep. 2016 Dec 8;6:38666. doi: 10.1038/srep38666.

23.

Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility.

Clausen TM, Pereira MA, Al Nakouzi N, Oo HZ, Agerbæk MØ, Lee S, Ørum-Madsen MS, Kristensen AR, El-Naggar A, Grandgenett PM, Grem JL, Hollingsworth MA, Holst PJ, Theander T, Sorensen PH, Daugaard M, Salanti A.

Mol Cancer Res. 2016 Dec;14(12):1288-1299. Epub 2016 Sep 21.

24.

Effect of HIV-1 envelope cytoplasmic tail on adenovirus primed virus encoded virus-like particle immunizations.

Andersson AC, Ragonnaud E, Seaton KE, Sawant S, Folgori A, Colloca S, Labranche C, Montefiori DC, Tomaras GD, Holst PJ.

Vaccine. 2016 Oct 17;34(44):5344-5351. doi: 10.1016/j.vaccine.2016.08.089. Epub 2016 Sep 12.

25.

American Confederation of Urology (CAU) experience in minimally invasive partial nephrectomy.

Secin FP, Castillo OA, Rozanec JJ, Featherston M, Holst P, Milfont JC, García Marchiñena P, Jurado Navarro A, Autrán A, Rovegno AR, Faba OR, Palou J, Teixeira Dubeux V, Nuñez Bragayrac L, Sotelo R, Zequi S, Guimarães GC, Álvarez-Maestro M, Martínez-Piñeiro L, Villoldo G, Villaronga A, Abreu Clavijo D, Decia R, Frota R, Vidal-Mora I, Finkelstein D, Monzó Gardiner JI, Schatloff O, Hernández-Porrás A, Santaella-Torres F, Quesada ET, Sánchez-Salas R, Dávila H, Mavric HV.

World J Urol. 2017 Jan;35(1):57-65. doi: 10.1007/s00345-016-1837-z. Epub 2016 Apr 30.

PMID:
27137994
26.

An adenoviral cancer vaccine co-encoding a tumor associated antigen together with secreted 4-1BBL leads to delayed tumor progression.

Ragonnaud E, Andersson AM, Pedersen AE, Laursen H, Holst PJ.

Vaccine. 2016 Apr 19;34(18):2147-56. doi: 10.1016/j.vaccine.2015.06.087. Epub 2016 Mar 19.

PMID:
27004934
27.

Combined local and systemic immunization is essential for durable T-cell mediated heterosubtypic immunity against influenza A virus.

Uddback IE, Pedersen LM, Pedersen SR, Steffensen MA, Holst PJ, Thomsen AR, Christensen JP.

Sci Rep. 2016 Feb 1;6:20137. doi: 10.1038/srep20137.

28.

Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein.

Salanti A, Clausen TM, Agerbæk MØ, Al Nakouzi N, Dahlbäck M, Oo HZ, Lee S, Gustavsson T, Rich JR, Hedberg BJ, Mao Y, Barington L, Pereira MA, LoBello J, Endo M, Fazli L, Soden J, Wang CK, Sander AF, Dagil R, Thrane S, Holst PJ, Meng L, Favero F, Weiss GJ, Nielsen MA, Freeth J, Nielsen TO, Zaia J, Tran NL, Trent J, Babcook JS, Theander TG, Sorensen PH, Daugaard M.

Cancer Cell. 2015 Oct 12;28(4):500-514. doi: 10.1016/j.ccell.2015.09.003.

29.

In-Flight Study of Helmet-Mounted Symbology System Concepts in Degraded Visual Environments.

Cheung B, Craig G, Steels B, Sceviour R, Cosman V, Jennings S, Holst P.

Aerosp Med Hum Perform. 2015 Aug;86(8):714-22. doi: 10.3357/AMHP.4231.2015.

PMID:
26387895
30.

Simulator Study of Helmet-Mounted Symbology System Concepts in Degraded Visual Environments.

Cheung B, McKinley RA, Steels B, Sceviour R, Cosman V, Holst P.

Aerosp Med Hum Perform. 2015 Jul;86(7):588-98. doi: 10.3357/AMHP.4232.2015.

PMID:
26102138
31.

Targeting of non-dominant antigens as a vaccine strategy to broaden T-cell responses during chronic viral infection.

Holst PJ, Jensen BA, Ragonnaud E, Thomsen AR, Christensen JP.

PLoS One. 2015 Feb 13;10(2):e0117242. doi: 10.1371/journal.pone.0117242. eCollection 2015.

32.

Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity.

Lee-Chang C, Bodogai M, Moritoh K, Olkhanud PB, Chan AC, Croft M, Mattison JA, Holst PJ, Gress RE, Ferrucci L, Hakim F, Biragyn A.

Blood. 2014 Aug 28;124(9):1450-9. doi: 10.1182/blood-2014-03-563940. Epub 2014 Jul 18.

33.

Co-expression of tumor antigen and interleukin-2 from an adenoviral vector augments the efficiency of therapeutic tumor vaccination.

Jensen BA, Steffensen MA, Nielsen KN, Christensen JP, Thomsen AR, Holst PJ.

Mol Ther. 2014 Dec;22(12):2107-17. doi: 10.1038/mt.2014.130. Epub 2014 Jul 15.

34.

The rationale of vectored gene-fusion vaccines against cancer: evolving strategies and latest evidence.

Ragonnaud E, Holst P.

Ther Adv Vaccines. 2013 May;1(1):33-47. doi: 10.1177/2051013613480446.

35.

IFNγ and perforin cooperate to control infection and prevent fatal pathology during persistent gammaherpesvirus infection in mice.

Bartholdy C, Høgh-Petersen M, Storm P, Holst PJ, Orskov C, Christensen JP, Thomsen AR.

Scand J Immunol. 2014 Jun;79(6):395-403. doi: 10.1111/sji.12176.

36.

Qualitative and quantitative analysis of adenovirus type 5 vector-induced memory CD8 T cells: not as bad as their reputation.

Steffensen MA, Holst PJ, Steengaard SS, Jensen BA, Bartholdy C, Stryhn A, Christensen JP, Thomsen AR.

J Virol. 2013 Jun;87(11):6283-95. doi: 10.1128/JVI.00465-13. Epub 2013 Mar 27.

37.

Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells.

Pedersen J, Ugleholdt RK, Jørgensen SM, Windeløv JA, Grunddal KV, Schwartz TW, Füchtbauer EM, Poulsen SS, Holst PJ, Holst JJ.

Am J Physiol Endocrinol Metab. 2013 Jan 1;304(1):E60-73. doi: 10.1152/ajpendo.00547.2011. Epub 2012 Oct 31.

38.

Pre-existing vector immunity does not prevent replication deficient adenovirus from inducing efficient CD8 T-cell memory and recall responses.

Steffensen MA, Jensen BA, Holst PJ, Bassi MR, Christensen JP, Thomsen AR.

PLoS One. 2012;7(4):e34884. doi: 10.1371/journal.pone.0034884. Epub 2012 Apr 13.

39.

Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain.

Ugleholdt R, Pedersen J, Bassi MR, Füchtbauer EM, Jørgensen SM, Kissow HL, Nytofte N, Poulsen SS, Rosenkilde MM, Seino Y, Thams P, Holst PJ, Holst JJ.

J Biol Chem. 2011 Dec 30;286(52):44632-45. doi: 10.1074/jbc.M111.311779. Epub 2011 Oct 25.

40.

Matrix metalloproteinase-8 overexpression prevents proper tissue repair.

Danielsen PL, Holst AV, Maltesen HR, Bassi MR, Holst PJ, Heinemeier KM, Olsen J, Danielsen CC, Poulsen SS, Jorgensen LN, Agren MS.

Surgery. 2011 Nov;150(5):897-906. doi: 10.1016/j.surg.2011.06.016. Epub 2011 Aug 27.

PMID:
21875735
41.

Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist.

Benned-Jensen T, Smethurst C, Holst PJ, Page KR, Sauls H, Sivertsen B, Schwartz TW, Blanchard A, Jepras R, Rosenkilde MM.

J Biol Chem. 2011 Aug 19;286(33):29292-302. doi: 10.1074/jbc.M110.196345. Epub 2011 Jun 14.

42.

Vaccination against lymphocytic choriomeningitis virus infection in MHC class II-deficient mice.

Holst PJ, Christensen JP, Thomsen AR.

J Immunol. 2011 Apr 1;186(7):3997-4007. doi: 10.4049/jimmunol.1001251. Epub 2011 Feb 28.

43.

Enhanced and sustained CD8+ T cell responses with an adenoviral vector-based hepatitis C virus vaccine encoding NS3 linked to the MHC class II chaperone protein invariant chain.

Mikkelsen M, Holst PJ, Bukh J, Thomsen AR, Christensen JP.

J Immunol. 2011 Feb 15;186(4):2355-64. doi: 10.4049/jimmunol.1001877. Epub 2011 Jan 21.

44.

Adenoviral vaccination combined with CD40 stimulation and CTLA-4 blockage can lead to complete tumor regression in a murine melanoma model.

Sorensen MR, Holst PJ, Steffensen MA, Christensen JP, Thomsen AR.

Vaccine. 2010 Sep 24;28(41):6757-64. doi: 10.1016/j.vaccine.2010.07.066. Epub 2010 Aug 2.

PMID:
20682365
45.

The murine gammaherpesvirus-68 chemokine-binding protein M3 inhibits experimental autoimmune encephalomyelitis.

Millward JM, Holst PJ, Høgh-Petersen M, Thomsen AR, Christensen JP, Owens T.

J Neuroimmunol. 2010 Jul 27;224(1-2):45-50. doi: 10.1016/j.jneuroim.2010.05.005.

PMID:
20537410
46.

Quality of the transgene-specific CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccination.

Holst PJ, Ørskov C, Thomsen AR, Christensen JP.

J Immunol. 2010 Apr 15;184(8):4431-9. doi: 10.4049/jimmunol.0900537. Epub 2010 Mar 8.

47.

Pain control after total knee arthroplasty: a prospective study comparing local infiltration anesthesia and epidural anesthesia.

Thorsell M, Holst P, Hyldahl HC, Weidenhielm L.

Orthopedics. 2010 Feb;33(2):75-80. doi: 10.3928/01477447-20100104-13.

PMID:
20192136
48.

Nephron-sparing surgery: our experience in open and laparoscopic approach in 254 cases.

Rozanec JJ, Ameri C, Holst P, Featherston M, Vallone C, Atchabahián P, Hernández A, Nolazco A, Ares J, Mazza O.

Arch Esp Urol. 2010 Jan-Feb;63(1):62-9.

PMID:
20157221
49.

DNA fusion gene vaccines.

Holst PJ, Bassi MR, Thomsen AR, Christensen JP.

Curr Opin Mol Ther. 2010 Feb;12(1):47-54. Review.

PMID:
20140816
50.

Structural basis of the aberrant receptor binding properties of hagfish and lamprey insulins.

Sajid W, Holst PA, Kiselyov VV, Andersen AS, Conlon JM, Kristensen C, Kjeldsen T, Whittaker J, Chan SJ, De Meyts P.

Biochemistry. 2009 Dec 1;48(47):11283-95. doi: 10.1021/bi901269j.

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