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Items: 1 to 50 of 290

1.

Translating biased signaling in the ghrelin receptor system into differential in vivo functions.

Mende F, Hundahl C, Plouffe B, Skov LJ, Sivertsen B, Madsen AN, Lückmann M, Diep TA, Offermanns S, Frimurer TM, Bouvier M, Holst B.

Proc Natl Acad Sci U S A. 2018 Oct 9. pii: 201804003. doi: 10.1073/pnas.1804003115. [Epub ahead of print]

PMID:
30301804
2.

Development of MS-based methods for identification and quantification of proteins altered during early pregnancy in dogs.

Valdés A, Holst BS, Lindersson S, Ramström M.

J Proteomics. 2018 Sep 10. pii: S1874-3919(18)30345-2. doi: 10.1016/j.jprot.2018.09.004. [Epub ahead of print]

PMID:
30213709
3.

Effect of insulin treatment on circulating insulin-like growth factor I and IGF-binding proteins in cats with diabetes mellitus.

Strage EM, Sundberg M, Holst BS, Andersson Franko M, Ramström M, Fall T, Lewitt M.

J Vet Intern Med. 2018 Sep;32(5):1579-1590. doi: 10.1111/jvim.15243. Epub 2018 Aug 16.

4.

Bending Rigidity of 2D Silica.

Büchner C, Eder SD, Nesse T, Kuhness D, Schlexer P, Pacchioni G, Manson JR, Heyde M, Holst B, Freund HJ.

Phys Rev Lett. 2018 Jun 1;120(22):226101. doi: 10.1103/PhysRevLett.120.226101.

PMID:
29906168
5.

Prevalence of interfering antibodies in dogs and cats evaluated using a species-independent assay.

Bergman D, Larsson A, Hansson-Hamlin H, Svensson A, Holst BS.

Vet Clin Pathol. 2018 Jun;47(2):205-212. doi: 10.1111/vcp.12612.

PMID:
29902338
6.

Fast resolution change in neutral helium atom microscopy.

Flatabø R, Eder SD, Ravn AK, Samelin B, Greve MM, Reisinger T, Holst B.

Rev Sci Instrum. 2018 May;89(5):053702. doi: 10.1063/1.5029385.

PMID:
29864796
7.

An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese.

Graae AS, Hollensted M, Kloppenborg JT, Mahendran Y, Schnurr TM, Appel EVR, Rask J, Nielsen TRH, Johansen MØ, Linneberg A, Jørgensen ME, Grarup N, Kadarmideen HN, Holst B, Pedersen O, Holm JC, Hansen T.

Diabetologia. 2018 Aug;61(8):1769-1779. doi: 10.1007/s00125-018-4640-0. Epub 2018 May 31.

8.

Synthesis and in Vitro Evaluation of Stabilized and Selective Neuromedin U-1 Receptor Agonists.

De Prins A, Martin C, Van Wanseele Y, Tömböly C, Tourwé D, Caveliers V, Holst B, Van Eeckhaut A, Rosenkilde MM, Smolders I, Ballet S.

ACS Med Chem Lett. 2018 Apr 23;9(5):496-501. doi: 10.1021/acsmedchemlett.8b00105. eCollection 2018 May 10.

PMID:
29795766
9.

An empirical examination of the conceptualization of companion animals.

Hoffmann R, Lagerkvist CJ, Hagberg Gustavsson M, Holst BS.

BMC Psychol. 2018 May 4;6(1):15. doi: 10.1186/s40359-018-0228-1.

10.

Exploring proximity effects and large depth of field in helium ion beam lithography: large-area dense patterns and tilted surface exposure.

Flatabø R, Agarwal A, Hobbs R, Greve MM, Holst B, Berggren KK.

Nanotechnology. 2018 Jul 6;29(27):275301. doi: 10.1088/1361-6528/aabe22. Epub 2018 Apr 13.

PMID:
29652671
11.

The different faces of mass action in virus assembly.

van der Holst B, Kegel WK, Zandi R, van der Schoot P.

J Biol Phys. 2018 Jun;44(2):163-179. doi: 10.1007/s10867-018-9487-6. Epub 2018 Apr 3.

12.

Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice.

Dall M, Penke M, Sulek K, Matz-Soja M, Holst B, Garten A, Kiess W, Treebak JT.

Mol Cell Endocrinol. 2018 Sep 15;473:245-256. doi: 10.1016/j.mce.2018.01.025. Epub 2018 Feb 2.

PMID:
29408602
13.

Overweight in adult cats: a cross-sectional study.

Öhlund M, Palmgren M, Holst BS.

Acta Vet Scand. 2018 Jan 19;60(1):5. doi: 10.1186/s13028-018-0359-7.

14.

Development of potent and proteolytically stable human neuromedin U receptor agonists.

De Prins A, Martin C, Van Wanseele Y, Skov LJ, Tömböly C, Tourwé D, Caveliers V, Van Eeckhaut A, Holst B, Rosenkilde MM, Smolders I, Ballet S.

Eur J Med Chem. 2018 Jan 20;144:887-897. doi: 10.1016/j.ejmech.2017.12.035. Epub 2017 Dec 14.

PMID:
29329072
15.

The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity.

Christoffersen C, Federspiel CK, Borup A, Christensen PM, Madsen AN, Heine M, Nielsen CH, Kjaer A, Holst B, Heeren J, Nielsen LB.

Cell Rep. 2018 Jan 2;22(1):175-188. doi: 10.1016/j.celrep.2017.12.029.

16.

Atmospheric escape from the TRAPPIST-1 planets and implications for habitability.

Dong C, Jin M, Lingam M, Airapetian VS, Ma Y, van der Holst B.

Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):260-265. doi: 10.1073/pnas.1708010115. Epub 2017 Dec 28.

17.

Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.

Ochalek A, Mihalik B, Avci HX, Chandrasekaran A, Téglási A, Bock I, Giudice ML, Táncos Z, Molnár K, László L, Nielsen JE, Holst B, Freude K, Hyttel P, Kobolák J, Dinnyés A.

Alzheimers Res Ther. 2017 Dec 1;9(1):90. doi: 10.1186/s13195-017-0317-z.

18.

Identifying ovarian tissue in the bitch using anti-Müllerian hormone (AMH) or luteinizing hormone (LH).

Alm H, Holst BS.

Theriogenology. 2018 Jan 15;106:15-20. doi: 10.1016/j.theriogenology.2017.09.028. Epub 2017 Sep 27.

PMID:
29028571
19.

Ghrelin-mediated inhibition of the TSH-stimulated function of differentiated human thyrocytes ex vivo.

Barington M, Brorson MM, Hofman-Bang J, Rasmussen ÅK, Holst B, Feldt-Rasmussen U.

PLoS One. 2017 Sep 20;12(9):e0184992. doi: 10.1371/journal.pone.0184992. eCollection 2017.

20.

Impact of focal cortical dysplasia Type IIIa on seizure outcome following anterior mesial temporal lobe resection for the treatment of epilepsy.

Dührsen L, Sauvigny T, House PM, Stodieck S, Holst B, Matschke J, Schön G, Westphal M, Martens T.

J Neurosurg. 2018 Jun;128(6):1668-1673. doi: 10.3171/2017.2.JNS161295. Epub 2017 Jul 28.

PMID:
28753112
21.

Exploring the Behavioral and Metabolic Phenotype Generated by Re-Introduction of the Ghrelin Receptor in the Ventral Tegmental Area.

Skov LJ, Jensen M, Christiansen SH, Ratner C, Woldbye DPD, Holst B.

Int J Mol Sci. 2017 Apr 26;18(5). pii: E914. doi: 10.3390/ijms18050914.

22.

Identification of SSEA-1 expressing enhanced reprogramming (SEER) cells in porcine embryonic fibroblasts.

Li D, Secher JO, Juhl M, Mashayekhi K, Nielsen TT, Holst B, Hyttel P, Freude KK, Hall VJ.

Cell Cycle. 2017 Jun 3;16(11):1070-1084. doi: 10.1080/15384101.2017.1315490. Epub 2017 Apr 20.

23.

Pannexin-2-deficiency sensitizes pancreatic β-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo.

Berchtold LA, Miani M, Diep TA, Madsen AN, Cigliola V, Colli M, Krivokapic JM, Pociot F, Eizirik DL, Meda P, Holst B, Billestrup N, Størling J.

Mol Cell Endocrinol. 2017 Jun 15;448:108-121. doi: 10.1016/j.mce.2017.04.001. Epub 2017 Apr 5.

PMID:
28390953
24.

Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience.

De Sousa PA, Steeg R, Wachter E, Bruce K, King J, Hoeve M, Khadun S, McConnachie G, Holder J, Kurtz A, Seltmann S, Dewender J, Reimann S, Stacey G, O'Shea O, Chapman C, Healy L, Zimmermann H, Bolton B, Rawat T, Atkin I, Veiga A, Kuebler B, Serano BM, Saric T, Hescheler J, Brüstle O, Peitz M, Thiele C, Geijsen N, Holst B, Clausen C, Lako M, Armstrong L, Gupta SK, Kvist AJ, Hicks R, Jonebring A, Brolén G, Ebneth A, Cabrera-Socorro A, Foerch P, Geraerts M, Stummann TC, Harmon S, George C, Streeter I, Clarke L, Parkinson H, Harrison PW, Faulconbridge A, Cherubin L, Burdett T, Trigueros C, Patel MJ, Lucas C, Hardy B, Predan R, Dokler J, Brajnik M, Keminer O, Pless O, Gribbon P, Claussen C, Ringwald A, Kreisel B, Courtney A, Allsopp TE.

Stem Cell Res. 2017 Apr;20:105-114. doi: 10.1016/j.scr.2017.03.002. Epub 2017 Mar 7.

25.

The association between the serum concentration of canine prostate specific esterase (CPSE) and the size of the canine prostate.

Holst BS, Holmroos E, Friling L, Hanås S, Langborg LM, Franko MA, Hansson K.

Theriogenology. 2017 Apr 15;93:33-39. doi: 10.1016/j.theriogenology.2017.01.032. Epub 2017 Jan 25.

PMID:
28257864
26.

Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons.

Aldana BI, Zhang Y, Lihme MF, Bak LK, Nielsen JE, Holst B, Hyttel P, Freude KK, Waagepetersen HS.

Neurochem Int. 2017 Jun;106:48-61. doi: 10.1016/j.neuint.2017.02.010. Epub 2017 Feb 24.

PMID:
28237843
27.

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B.

Zhang Y, Schmid B, Nikolaisen NK, Rasmussen MA, Aldana BI, Agger M, Calloe K, Stummann TC, Larsen HM, Nielsen TT, Huang J, Xu F, Liu X, Bolund L, Meyer M, Bak LK, Waagepetersen HS, Luo Y, Nielsen JE; FReJA Consortium, Holst B, Clausen C, Hyttel P, Freude KK.

Stem Cell Reports. 2017 Mar 14;8(3):648-658. doi: 10.1016/j.stemcr.2017.01.012. Epub 2017 Feb 16.

28.

Maraviroc as possible treatment for PML-IRIS in natalizumab-treated patients with MS.

Hodecker SC, Stürner KH, Becker V, Elias-Hamp B, Holst B, Friese MA, Heesen C.

Neurol Neuroimmunol Neuroinflamm. 2017 Feb 8;4(2):e325. doi: 10.1212/NXI.0000000000000325. eCollection 2017 Mar. No abstract available.

29.

Ruxolitinib treatment in a patient with neuromyelitis optica: A case report.

Hodecker SC, Stellmann JP, Rosenkranz SC, Young K, Holst B, Friese MA, Heesen C.

Neurol Neuroimmunol Neuroinflamm. 2017 Feb 3;4(2):e328. doi: 10.1212/NXI.0000000000000328. eCollection 2017 Mar. No abstract available.

30.

Soluble Toll-like receptor 2 is a biomarker for sepsis in critically ill patients with multi-organ failure within 12 h of ICU admission.

Holst B, Szakmany T, Raby AC, Hamlyn V, Durno K, Hall JE, Labéta MO.

Intensive Care Med Exp. 2017 Dec;5(1):2. doi: 10.1186/s40635-016-0116-z. Epub 2017 Jan 13.

31.

T1 Recovery Is Predominantly Found in Black Holes and Is Associated with Clinical Improvement in Patients with Multiple Sclerosis.

Thaler C, Faizy TD, Sedlacik J, Holst B, Stürner K, Heesen C, Stellmann JP, Fiehler J, Siemonsen S.

AJNR Am J Neuroradiol. 2017 Feb;38(2):264-269. doi: 10.3174/ajnr.A5004. Epub 2016 Nov 10.

32.

Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions.

Frimurer TM, Mende F, Graae AS, Engelstoft MS, Egerod KL, Nygaard R, Gerlach LO, Hansen JB, Schwartz TW, Holst B.

J Med Chem. 2017 Feb 9;60(3):886-898. doi: 10.1021/acs.jmedchem.6b00648. Epub 2017 Jan 23.

PMID:
28045522
33.

Apparatus for measuring pressure-driven transport through channels at high Knudsen numbers.

Karakitsiou S, Holst B, Hoffmann AC.

Rev Sci Instrum. 2016 Dec;87(12):125104. doi: 10.1063/1.4963695.

PMID:
28040955
34.

Generation of an isogenic, gene-corrected iPSC line from a pre-symptomatic 28-year-old woman with an R406W mutation in the microtubule associated protein tau (MAPT) gene.

Nimsanor N, Poulsen U, Rasmussen MA, Clausen C, Mau-Holzmann UA, Nielsen JE, Nielsen TT, Hyttel P, Holst B, Schmid B.

Stem Cell Res. 2016 Nov;17(3):600-602. doi: 10.1016/j.scr.2016.09.024. Epub 2016 Sep 28.

35.

Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene.

Nimsanor N, Poulsen U, Rasmussen MA, Clausen C, Mau-Holzmann UA, Nielsen JE, Nielsen TT, Hyttel P, Holst B, Schmid B.

Stem Cell Res. 2016 Nov;17(3):576-579. doi: 10.1016/j.scr.2016.09.020. Epub 2016 Sep 28.

36.

Quantitative and Selective Analysis of Feline Growth Related Proteins Using Parallel Reaction Monitoring High Resolution Mass Spectrometry.

Sundberg M, Strage EM, Bergquist J, Holst BS, Ramström M.

PLoS One. 2016 Dec 1;11(12):e0167138. doi: 10.1371/journal.pone.0167138. eCollection 2016.

37.

Environmental Risk Factors for Diabetes Mellitus in Cats.

Öhlund M, Egenvall A, Fall T, Hansson-Hamlin H, Röcklinsberg H, Holst BS.

J Vet Intern Med. 2017 Jan;31(1):29-35. doi: 10.1111/jvim.14618. Epub 2016 Dec 1.

38.

Atomic resolution imaging of beryl: an investigation of the nano-channel occupation.

Arivazhagan V, Schmitz FD, Vullum PE, VAN Helvoort AT, Holst B.

J Microsc. 2017 Feb;265(2):245-250. doi: 10.1111/jmi.12493. Epub 2016 Nov 3.

PMID:
27809347
39.

Induced pluripotent stem cells (iPSCs) derived from a symptomatic carrier of a S305I mutation in the microtubule-associated protein tau (MAPT)-gene causing frontotemporal dementia.

Nimsanor N, Jørring I, Rasmussen MA, Clausen C, Mau-Holzmann UA, Kitiyanant N, Nielsen JE, Nielsen TT, Hyttel P, Holst B, Schmid B.

Stem Cell Res. 2016 Nov;17(3):564-567. doi: 10.1016/j.scr.2016.10.006. Epub 2016 Oct 20.

40.

Generation of an isogenic, gene-corrected iPSC line from a symptomatic 57-year-old female patient with frontotemporal dementia caused by a P301L mutation in the microtubule associated protein tau (MAPT) gene.

Nimsanor N, Kitiyanant N, Poulsen U, Rasmussen MA, Clausen C, Mau-Holzmann UA, Nielsen JE, Nielsen TT, Hyttel P, Holst B, Schmid B.

Stem Cell Res. 2016 Nov;17(3):556-559. doi: 10.1016/j.scr.2016.09.021. Epub 2016 Sep 28.

41.

Generation of induced pluripotent stem cells derived from a 77-year-old healthy woman as control for age related diseases.

Nimsanor N, Jørring I, Rasmussen MA, Clausen C, Mau-Holzmann UA, Bus C, Hoffmann SA, Gasser T, Kluba T, Holst B, Schmid B.

Stem Cell Res. 2016 Nov;17(3):550-552. doi: 10.1016/j.scr.2016.09.019. Epub 2016 Sep 28.

42.

Derivation of induced pluripotent stem cells from a familial Alzheimer's disease patient carrying the L282F mutation in presenilin 1.

Poon A, Li T, Pires C, Nielsen TT, Nielsen JE, Holst B, Dinnyes A, Hyttel P, Freude KK.

Stem Cell Res. 2016 Nov;17(3):470-473. doi: 10.1016/j.scr.2016.09.016. Epub 2016 Sep 28.

43.

Generation of a gene-corrected isogenic control hiPSC line derived from a familial Alzheimer's disease patient carrying a L150P mutation in presenilin 1.

Poon A, Schmid B, Pires C, Nielsen TT, Hjermind LE, Nielsen JE, Holst B, Hyttel P, Freude KK.

Stem Cell Res. 2016 Nov;17(3):466-469. doi: 10.1016/j.scr.2016.09.018. Epub 2016 Sep 24.

44.

GPR119, a Major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Coacting in Synergy With FFA1 (GPR40).

Ekberg JH, Hauge M, Kristensen LV, Madsen AN, Engelstoft MS, Husted AS, Sichlau R, Egerod KL, Timshel P, Kowalski TJ, Gribble FM, Reiman F, Hansen HS, Howard AD, Holst B, Schwartz TW.

Endocrinology. 2016 Dec;157(12):4561-4569. Epub 2016 Oct 25.

PMID:
27779915
45.

Animal obesity: causes, consequences and comparative aspects.

Holst BS, Gustavsson MH.

Acta Vet Scand. 2016 Oct 20;58(Suppl 1):56. No abstract available.

46.

Diagnostic possibilities from a serum sample-Clinical value of new methods within small animal reproduction, with focus on anti-Müllerian hormone.

Holst BS.

Reprod Domest Anim. 2017 Apr;52 Suppl 2:303-309. doi: 10.1111/rda.12856. Epub 2016 Oct 18. Review.

PMID:
27758004
47.

High molecular weight PEGylation of human pancreatic polypeptide at position 22 improves stability and reduces food intake in mice.

Thieme V, Jolly N, Madsen AN, Bellmann-Sickert K, Schwartz TW, Holst B, Cox HM, Beck-Sickinger AG.

Br J Pharmacol. 2016 Nov;173(22):3208-3221. doi: 10.1111/bph.13582. Epub 2016 Oct 5.

48.

Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery.

Ratner C, Skov LJ, Raida Z, Bächler T, Bellmann-Sickert K, Le Foll C, Sivertsen B, Dalbøge LS, Hartmann B, Beck-Sickinger AG, Madsen AN, Jelsing J, Holst JJ, Lutz TA, Andrews ZB, Holst B.

Endocrinology. 2016 Sep;157(9):3482-92. doi: 10.1210/en.2016-1329. Epub 2016 Jul 20.

PMID:
27580810
49.

Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific homozygous mutation in CHMP2B.

Zhang Y, Schmid B, Nielsen TT, Nielsen JE, Clausen C, Hyttel P, Holst B, Freude KK.

Stem Cell Res. 2016 Jul;17(1):151-153. doi: 10.1016/j.scr.2016.06.005. Epub 2016 Jun 16.

50.

Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B.

Zhang Y, Schmid B, Nielsen TT, Nielsen JE, Clausen C, Hyttel P, Holst B, Freude KK.

Stem Cell Res. 2016 Jul;17(1):148-150. doi: 10.1016/j.scr.2016.06.004. Epub 2016 Jun 16.

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