Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 172


Short chain ceramides disrupt immunoreceptor signaling by inhibiting segregation of Lo from Ld Plasma membrane components.

Holowka D, Thanapuasuwan K, Baird B.

Biol Open. 2018 Sep 27;7(9). pii: bio034702. doi: 10.1242/bio.034702.


Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity.

Jain P, Nattakom M, Holowka D, Wang DH, Thomas Brenna J, Ku AT, Nguyen H, Ibrahim SF, Tumbar T.

Stem Cells. 2018 Oct;36(10):1603-1616. doi: 10.1002/stem.2868. Epub 2018 Jul 29.


Computation of a Theoretical Membrane Phase Diagram and the Role of Phase in Lipid-Raft-Mediated Protein Organization.

Mitra ED, Whitehead SC, Holowka D, Baird B, Sethna JP.

J Phys Chem B. 2018 Apr 5;122(13):3500-3513. doi: 10.1021/acs.jpcb.7b10695. Epub 2018 Feb 21.


Editorial: Molecular Organization of Membranes: Where Biology Meets Biophysics.

Cebecauer M, Holowka D.

Front Cell Dev Biol. 2017 Dec 13;5:113. doi: 10.3389/fcell.2017.00113. eCollection 2017. No abstract available.


Timescale Separation of Positive and Negative Signaling Creates History-Dependent Responses to IgE Receptor Stimulation.

Harmon B, Chylek LA, Liu Y, Mitra ED, Mahajan A, Saada EA, Schudel BR, Holowka DA, Baird BA, Wilson BS, Hlavacek WS, Singh AK.

Sci Rep. 2017 Nov 14;7(1):15586. doi: 10.1038/s41598-017-15568-2.


The FcεRI Signaling Cascade and Integrin Trafficking Converge at Patterned Ligand Surfaces.

Wakefield DL, Holowka D, Baird B.

Mol Biol Cell. 2017 Aug 9. pii: mbc.E17-03-0208. doi: 10.1091/mbc.E17-03-0208. [Epub ahead of print]


Examining the diagnostic utility of the DSM-5 PTSD symptoms among male and female returning veterans.

Green JD, Annunziata A, Kleiman SE, Bovin MJ, Harwell AM, Fox AML, Black SK, Schnurr PP, Holowka DW, Rosen RC, Keane TM, Marx BP.

Depress Anxiety. 2017 Aug;34(8):752-760. doi: 10.1002/da.22667. Epub 2017 Aug 1.


Molecular anatomy of the early events in STIM1 activation - oligomerization or conformational change?

Korzeniowski MK, Wisniewski E, Baird B, Holowka DA, Balla T.

J Cell Sci. 2017 Sep 1;130(17):2821-2832. doi: 10.1242/jcs.205583. Epub 2017 Jul 19.


The influence of veteran race and psychometric testing on veterans affairs posttraumatic stress disorder (PTSD) disability exam outcomes.

Marx BP, Engel-Rebitzer E, Bovin MJ, Parker-Guilbert KS, Moshier S, Barretto K, Szafranski D, Gallagher MW, Holowka DW, Rosen RC, Keane TM.

Psychol Assess. 2017 Jun;29(6):710-719. doi: 10.1037/pas0000378.


Mechanisms of epidermal growth factor receptor signaling as characterized by patterned ligand activation and mutational analysis.

Holowka D, Baird B.

Biochim Biophys Acta Biomembr. 2017 Sep;1859(9 Pt A):1430-1435. doi: 10.1016/j.bbamem.2016.12.015. Epub 2016 Dec 24. Review.


Graphene Oxide Nanosheets Stimulate Ruffling and Shedding of Mammalian Cell Plasma Membranes.

Sun C, Wakefield DL, Han Y, Muller DA, Holowka DA, Baird BA, Dichtel WR.

Chem. 2016 Aug 11;1(2):273-286.


Functional nanoscale coupling of Lyn kinase with IgE-FcεRI is restricted by the actin cytoskeleton in early antigen-stimulated signaling.

Shelby SA, Veatch SL, Holowka DA, Baird BA.

Mol Biol Cell. 2016 Nov 7;27(22):3645-3658. Epub 2016 Sep 28.


Mild Traumatic Brain Injury, PTSD, and Psychosocial Functioning Among Male and Female U.S. OEF/OIF Veterans.

Jackson CE, Green JD, Bovin MJ, Vasterling JJ, Holowka DW, Ranganathan G, Rosen RC, Keane TM, Marx BP.

J Trauma Stress. 2016 Aug;29(4):309-16. doi: 10.1002/jts.22110. Epub 2016 Jul 12.


Rab11 Regulates the Mast Cell Exocytic Response.

Wilson JD, Shelby SA, Holowka D, Baird B.

Traffic. 2016 Sep;17(9):1027-41. doi: 10.1111/tra.12418. Epub 2016 Jul 11.


STIM1 activation is regulated by a 14 amino acid sequence adjacent to the CRAC activation domain.

Korzeniowski MK, Baird B, Holowka D.

AIMS Biophys. 2016;3(1):99-118. Epub 2016 Feb 28.


Roles for Ca2+ mobilization and its regulation in mast cell functions: recent progress.

Holowka D, Wilkes M, Stefan C, Baird B.

Biochem Soc Trans. 2016 Apr 15;44(2):505-9. doi: 10.1042/BST20150273. Review.


Roles for lipid heterogeneity in immunoreceptor signaling.

Holowka D, Baird B.

Biochim Biophys Acta. 2016 Aug;1861(8 Pt B):830-836. doi: 10.1016/j.bbalip.2016.03.019. Epub 2016 Mar 17. Review.


Validity of posttraumatic stress disorder service connection status in Veterans Affairs electronic records of Iraq and Afghanistan Veterans.

Marx BP, Bovin MJ, Szafranski DD, Engel-Rebitzer E, Gallagher MW, Holowka DW, Schnurr PP, Rosen RC, Keane TM.

J Clin Psychiatry. 2016 Apr;77(4):517-22. doi: 10.4088/JCP.14m09666.


Non-Faradaic Electrochemical Detection of Exocytosis from Mast and Chromaffin Cells Using Floating-Gate MOS Transistors.

Jayant K, Singhai A, Cao Y, Phelps JB, Lindau M, Holowka DA, Baird BA, Kan EC.

Sci Rep. 2015 Dec 21;5:18477. doi: 10.1038/srep18477.


Psychosocial Functioning and Health-Related Quality of Life Associated with Posttraumatic Stress Disorder in Male and Female Iraq and Afghanistan War Veterans: The VALOR Registry.

Fang SC, Schnurr PP, Kulish AL, Holowka DW, Marx BP, Keane TM, Rosen R.

J Womens Health (Larchmt). 2015 Dec;24(12):1038-46. doi: 10.1089/jwh.2014.5096. Epub 2015 Jul 23.


Examining trauma and posttraumatic stress disorder symptoms in court-mandated intimate partner violence perpetrators.

Maguire E, Macdonald A, Krill S, Holowka DW, Marx BP, Woodward H, Burns T, Taft CT.

Psychol Trauma. 2015 Sep;7(5):473-8. doi: 10.1037/a0039253. Epub 2015 May 25.


Nanodomains in early and later phases of FcɛRI signalling.

Holowka D, Baird B.

Essays Biochem. 2015;57:147-63. doi: 10.1042/bse0570147.


Spatially defined EGF receptor activation reveals an F-actin-dependent phospho-Erk signaling complex.

Singhai A, Wakefield DL, Bryant KL, Hammes SR, Holowka D, Baird B.

Biophys J. 2014 Dec 2;107(11):2639-51. doi: 10.1016/j.bpj.2014.09.048. Epub 2014 Dec 2.


Real-time imaging of Ca(2+) mobilization and degranulation in mast cells.

Cohen R, Holowka DA, Baird BA.

Methods Mol Biol. 2015;1220:347-63. doi: 10.1007/978-1-4939-1568-2_22.


Near-field fluorescence cross-correlation spectroscopy on planar membranes.

Kelly CV, Wakefield DL, Holowka DA, Craighead HG, Baird BA.

ACS Nano. 2014 Jul 22;8(7):7392-404. doi: 10.1021/nn502593k. Epub 2014 Jul 11.


Activation of Cdc42 is necessary for sustained oscillations of Ca2+ and PIP2 stimulated by antigen in RBL mast cells.

Wilkes MM, Wilson JD, Baird B, Holowka D.

Biol Open. 2014 Jul 4;3(8):700-10. doi: 10.1242/bio.20148862.


An Interaction Library for the FcεRI Signaling Network.

Chylek LA, Holowka DA, Baird BA, Hlavacek WS.

Front Immunol. 2014 Apr 15;5:172. doi: 10.3389/fimmu.2014.00172. eCollection 2014. Review.


Polyunsaturated fatty acids inhibit stimulated coupling between the ER Ca(2+) sensor STIM1 and the Ca(2+) channel protein Orai1 in a process that correlates with inhibition of stimulated STIM1 oligomerization.

Holowka D, Korzeniowski MK, Bryant KL, Baird B.

Biochim Biophys Acta. 2014 Aug;1841(8):1210-6. doi: 10.1016/j.bbalip.2014.04.006. Epub 2014 Apr 24.


PTSD diagnostic validity in Veterans Affairs electronic records of Iraq and Afghanistan veterans.

Holowka DW, Marx BP, Gates MA, Litman HJ, Ranganathan G, Rosen RC, Keane TM.

J Consult Clin Psychol. 2014 Aug;82(4):569-579. doi: 10.1037/a0036347. Epub 2014 Apr 14. Erratum in: J Consult Clin Psychol. 2014 Aug;82(4):579.


Traumatic brain injury, PTSD, and current suicidal ideation among Iraq and Afghanistan U.S. veterans.

Wisco BE, Marx BP, Holowka DW, Vasterling JJ, Han SC, Chen MS, Gradus JL, Nock MK, Rosen RC, Keane TM.

J Trauma Stress. 2014 Apr;27(2):244-8. doi: 10.1002/jts.21900. Epub 2014 Mar 17.


Distinct stages of stimulated FcεRI receptor clustering and immobilization are identified through superresolution imaging.

Shelby SA, Holowka D, Baird B, Veatch SL.

Biophys J. 2013 Nov 19;105(10):2343-54. doi: 10.1016/j.bpj.2013.09.049.


Mutations in the polybasic juxtamembrane sequence of both plasma membrane- and endoplasmic reticulum-localized epidermal growth factor receptors confer ligand-independent cell transformation.

Bryant KL, Antonyak MA, Cerione RA, Baird B, Holowka D.

J Biol Chem. 2013 Nov 29;288(48):34930-42. doi: 10.1074/jbc.M113.513333. Epub 2013 Oct 18.


Maladaptive dependency schemas, posttraumatic stress hyperarousal symptoms, and intimate partner aggression perpetration.

Kachadourian LK, Taft CT, Holowka DW, Woodward H, Marx BP, Burns A.

J Trauma Stress. 2013 Oct;26(5):580-7. doi: 10.1002/jts.21850. Epub 2013 Sep 12.


Toxoplasma gondii inhibits mast cell degranulation by suppressing phospholipase Cγ-mediated Ca(2+) mobilization.

Smith NL, Abi Abdallah DS, Butcher BA, Denkers EY, Baird B, Holowka D.

Front Microbiol. 2013 Jul 4;4:179. doi: 10.3389/fmicb.2013.00179. eCollection 2013.


Childhood trauma and dissociation in first-episode psychosis, chronic schizophrenia and community controls.

Braehler C, Valiquette L, Holowka D, Malla AK, Joober R, Ciampi A, Pawliuk N, King S.

Psychiatry Res. 2013 Nov 30;210(1):36-42. doi: 10.1016/j.psychres.2013.05.033. Epub 2013 Jun 29.


Inhibitors of PI(4,5)P2 synthesis reveal dynamic regulation of IgE receptor signaling by phosphoinositides in RBL mast cells.

Santos Mde S, Naal RM, Baird B, Holowka D.

Mol Pharmacol. 2013 Apr;83(4):793-804. doi: 10.1124/mol.112.082834. Epub 2013 Jan 11.


Posttraumatic stress disorder in veterans and military personnel: epidemiology, screening, and case recognition.

Gates MA, Holowka DW, Vasterling JJ, Keane TM, Marx BP, Rosen RC.

Psychol Serv. 2012 Nov;9(4):361-82. doi: 10.1037/a0027649. Epub 2012 Mar 5. Review.


In vitro modelling of rat mucosal mast cell function in Trichinella spiralis infection.

Thrasher SM, Scalfone LK, Holowka D, Appleton JA.

Parasite Immunol. 2013 Jan;35(1):21-31. doi: 10.1111/pim.12014.


Assessment of posttraumatic stress disorder-related functional impairment: a review.

Rodriguez P, Holowka DW, Marx BP.

J Rehabil Res Dev. 2012;49(5):649-65. Review.


Molecular mechanisms of spontaneous and directed mast cell motility.

Lee J, Veatch SL, Baird B, Holowka D.

J Leukoc Biol. 2012 Nov;92(5):1029-41. doi: 10.1189/jlb.0212091. Epub 2012 Aug 2.


Roles for ca(2+) mobilization and its regulation in mast cell functions.

Holowka D, Calloway N, Cohen R, Gadi D, Lee J, Smith NL, Baird B.

Front Immunol. 2012 May 8;3:104. doi: 10.3389/fimmu.2012.00104. eCollection 2012.


Quantitative nanoscale analysis of IgE-FcεRI clustering and coupling to early signaling proteins.

Veatch SL, Chiang EN, Sengupta P, Holowka DA, Baird BA.

J Phys Chem B. 2012 Jun 14;116(23):6923-35. doi: 10.1021/jp300197p. Epub 2012 Apr 2.


Spatiotemporal resolution of mast cell granule exocytosis reveals correlation with Ca2+ wave initiation.

Cohen R, Corwith K, Holowka D, Baird B.

J Cell Sci. 2012 Jun 15;125(Pt 12):2986-94. doi: 10.1242/jcs.102632. Epub 2012 Mar 5.


Correlation functions quantify super-resolution images and estimate apparent clustering due to over-counting.

Veatch SL, Machta BB, Shelby SA, Chiang EN, Holowka DA, Baird BA.

PLoS One. 2012;7(2):e31457. doi: 10.1371/journal.pone.0031457. Epub 2012 Feb 27.


Project VALOR: design and methods of a longitudinal registry of post-traumatic stress disorder (PTSD) in combat-exposed veterans in the Afghanistan and Iraqi military theaters of operations.

Rosen RC, Marx BP, Maserejian NN, Holowka DW, Gates MA, Sleeper LA, Vasterling JJ, Kang HK, Keane TM.

Int J Methods Psychiatr Res. 2012 Mar;21(1):5-16. doi: 10.1002/mpr.355. Epub 2011 Nov 16.


Sequestration of phosphoinositides by mutated MARCKS effector domain inhibits stimulated Ca(2+) mobilization and degranulation in mast cells.

Gadi D, Wagenknecht-Wiesner A, Holowka D, Baird B.

Mol Biol Cell. 2011 Dec;22(24):4908-17. doi: 10.1091/mbc.E11-07-0614. Epub 2011 Oct 19.


Stimulated association of STIM1 and Orai1 is regulated by the balance of PtdIns(4,5)P₂ between distinct membrane pools.

Calloway N, Owens T, Corwith K, Rodgers W, Holowka D, Baird B.

J Cell Sci. 2011 Aug 1;124(Pt 15):2602-10. doi: 10.1242/jcs.084178. Epub 2011 Jul 12.


Micropatterned ligand arrays to study spatial regulation in Fc receptor signaling.

Torres AJ, Holowka D, Baird BA.

Methods Mol Biol. 2011;748:195-207. doi: 10.1007/978-1-61779-139-0_14.


Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells.

Antonyak MA, Li B, Boroughs LK, Johnson JL, Druso JE, Bryant KL, Holowka DA, Cerione RA.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4852-7. doi: 10.1073/pnas.1017667108. Epub 2011 Feb 28. Erratum in: Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17569.

Supplemental Content

Loading ...
Support Center