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Items: 1 to 50 of 111

1.

Status epilepticus alters neurogenesis and decreases the number of GABAergic neurons in the septal dentate gyrus of 9-day-old rats at the early phase of epileptogenesis.

Laurén HB, Ruohonen S, Kukko-Lukjanov TK, Virta JE, Grönman M, Lopez-Picon FR, Järvelä JT, Holopainen IE.

Brain Res. 2013 Jun 21;1516:33-44. doi: 10.1016/j.brainres.2013.04.028. Epub 2013 Apr 24.

PMID:
23623775
2.

Histamine 1 receptor knock out mice show age-dependent susceptibility to status epilepticus and consequent neuronal damage.

Kukko-Lukjanov TK, Grönman M, Lintunen M, Laurén HB, Michelsen KA, Panula P, Holopainen IE.

Epilepsy Res. 2012 Jun;100(1-2):80-92. doi: 10.1016/j.eplepsyres.2012.01.011. Epub 2012 Feb 19.

PMID:
22348791
3.

Temporal profiles of age-dependent changes in cytokine mRNA expression and glial cell activation after status epilepticus in postnatal rat hippocampus.

Järvelä JT, Lopez-Picon FR, Plysjuk A, Ruohonen S, Holopainen IE.

J Neuroinflammation. 2011 Apr 8;8:29. doi: 10.1186/1742-2094-8-29.

4.

Glutamate signaling in the pathophysiology and therapy of prenatal insults.

Holopainen IE, Laurén HB.

Pharmacol Biochem Behav. 2012 Feb;100(4):825-34. doi: 10.1016/j.pbb.2011.03.016. Epub 2011 Apr 2. Review.

PMID:
21443898
5.

Kainic acid-induced neurodegeneration and activation of inflammatory processes in organotypic hippocampal slice cultures: treatment with cyclooxygenase-2 inhibitor does not prevent neuronal death.

Järvelä JT, Ruohonen S, Kukko-Lukjanov TK, Plysjuk A, Lopez-Picon FR, Holopainen IE.

Neuropharmacology. 2011 Jun;60(7-8):1116-25. doi: 10.1016/j.neuropharm.2010.09.024. Epub 2010 Oct 7.

PMID:
20932983
6.

Auditory event related potentials as tools to reveal cognitive late effects in childhood cancer patients.

Järvelä LS, Hurme S, Holopainen IE, Leino M, Hatanpää AM, Mikola H, Kärki T, Salmi TT, Lähteenmäki PM.

Clin Neurophysiol. 2011 Jan;122(1):62-72. doi: 10.1016/j.clinph.2010.05.031. Epub 2010 Jul 6.

PMID:
20609620
7.

Transcriptome analysis of the hippocampal CA1 pyramidal cell region after kainic acid-induced status epilepticus in juvenile rats.

Laurén HB, Lopez-Picon FR, Brandt AM, Rios-Rojas CJ, Holopainen IE.

PLoS One. 2010 May 20;5(5):e10733. doi: 10.1371/journal.pone.0010733.

8.

Sex, age, and tissue specific accumulation of eight metals, arsenic, and selenium in the European hedgehog (Erinaceus europaeus).

Rautio A, Kunnasranta M, Valtonen A, Ikonen M, Hyvärinen H, Holopainen IJ, Kukkonen JV.

Arch Environ Contam Toxicol. 2010 Nov;59(4):642-51. doi: 10.1007/s00244-010-9503-8. Epub 2010 Apr 7.

PMID:
20372884
9.

Involvement of histamine 1 receptor in seizure susceptibility and neuroprotection in immature mice.

Kukko-Lukjanov TK, Lintunen M, Jalava N, Laurén HB, Lopez-Picon FR, Michelsen KA, Panula P, Holopainen IE.

Epilepsy Res. 2010 Jun;90(1-2):8-15. doi: 10.1016/j.eplepsyres.2010.02.012. Epub 2010 Mar 31.

PMID:
20359868
10.

[Mechanisms of action and clinical use of antiepileptic drugs].

Keränen T, Holopainen I.

Duodecim. 2009;125(22):2533-40. Review. Finnish.

PMID:
20095122
11.

Aquatic environment and differentiation of vibrissae: comparison of sinus hair systems of ringed seal, otter and pole cat.

Hyvärinen H, Palviainen A, Strandberg U, Holopainen IJ.

Brain Behav Evol. 2009;74(4):268-79. doi: 10.1159/000264662. Epub 2009 Dec 8.

PMID:
19996585
12.
13.

Age-dependent cyclooxygenase-2 induction and neuronal damage after status epilepticus in the postnatal rat hippocampus.

Järvelä JT, Lopez-Picon FR, Holopainen IE.

Epilepsia. 2008 May;49(5):832-41. Epub 2007 Dec 10.

14.

Placenta defects and embryonic lethality resulting from disruption of mouse hydroxysteroid (17-beta) dehydrogenase 2 gene.

Rantakari P, Strauss L, Kiviranta R, Lagerbohm H, Paviala J, Holopainen I, Vainio S, Pakarinen P, Poutanen M.

Mol Endocrinol. 2008 Mar;22(3):665-75. Epub 2007 Nov 29.

15.

Physiological and biochemical effects of lithium in rainbow trout.

Tkatcheva V, Franklin NM, McClelland GB, Smith RW, Holopainen IJ, Wood CM.

Arch Environ Contam Toxicol. 2007 Nov;53(4):632-8. Epub 2007 Sep 19.

PMID:
17882473
16.
17.

The responses of rainbow trout gills to high lithium and potassium concentrations in water.

Tkatcheva V, Holopainen IJ, Hyvärinen H, Kukkonen JV.

Ecotoxicol Environ Saf. 2007 Nov;68(3):419-25. Epub 2007 May 16.

PMID:
17509685
18.

Status epilepticus alters zolpidem sensitivity of [3H]flunitrazepam binding in the developing rat brain.

Laurén HB, Lopez-Picon FR, Kukko-Lukjanov TK, Uusi-Oukari M, Holopainen IE.

Neuroscience. 2007 May 11;146(2):802-11. Epub 2007 Mar 13.

PMID:
17360122
19.

Changes in microtubule-associated protein-2 (MAP2) expression during development and after status epilepticus in the immature rat hippocampus.

Jalava NS, Lopez-Picon FR, Kukko-Lukjanov TK, Holopainen IE.

Int J Dev Neurosci. 2007 Apr;25(2):121-31. Epub 2006 Dec 20.

PMID:
17229541
21.

Inhaled nitric oxide treatment inhibits neuronal injury after meconium aspiration in piglets.

Aaltonen M, Soukka H, Halkola L, Jalonen J, Kalimo H, Holopainen IE, Kääpä PO.

Early Hum Dev. 2007 Feb;83(2):77-85. Epub 2006 Jun 21.

PMID:
16793227
22.

AMPA/kainate receptor-mediated up-regulation of GABAA receptor delta subunit mRNA expression in cultured rat cerebellar granule cells is dependent on NMDA receptor activation.

Salonen V, Kallinen S, Lopez-Picon FR, Korpi ER, Holopainen IE, Uusi-Oukari M.

Brain Res. 2006 May 4;1087(1):33-40. Epub 2006 Apr 13.

PMID:
16626639
23.

Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system.

Kukko-Lukjanov TK, Soini S, Taira T, Michelsen KA, Panula P, Holopainen IE.

J Neurosci. 2006 Jan 25;26(4):1088-97.

25.

Meconium aspiration induces neuronal injury in piglets.

Aaltonen M, Soukka H, Halkola L, Kalimo H, Holopainen IE, Kääpä PO.

Acta Paediatr. 2005 Oct;94(10):1468-75.

PMID:
16299879
26.

Histamine-immunoreactive neurons in the mouse and rat suprachiasmatic nucleus.

Michelsen KA, Lozada A, Kaslin J, Karlstedt K, Kukko-Lukjanov TK, Holopainen I, Ohtsu H, Panula P.

Eur J Neurosci. 2005 Oct;22(8):1997-2004.

PMID:
16262638
27.

Kainic acid-induced status epilepticus alters GABA receptor subunit mRNA and protein expression in the developing rat hippocampus.

Laurén HB, Lopez-Picon FR, Korpi ER, Holopainen IE.

J Neurochem. 2005 Sep;94(5):1384-94. Epub 2005 Jun 30.

28.

Meconium aspiration induces oxidative injury in the hippocampus of newborn piglets.

Aaltonen M, Soukka H, Halkola L, Jalonen J, Holopainen IE, Kääpä PO.

Early Hum Dev. 2005 May;81(5):439-47.

PMID:
15922523
29.
30.

Maturation of cultured hippocampal slices results in increased excitability in granule cells.

Lindroos MM, Soini SL, Kukko-Lukjanov TK, Korpi ER, Lovinger D, Holopainen IE.

Int J Dev Neurosci. 2005 Feb;23(1):65-73.

PMID:
15730888
31.
32.

Mechanisms of kainate-induced region-specific neuronal death in immature organotypic hippocampal slice cultures.

Holopainen IE, Järvelä J, Lopez-Picon FR, Pelliniemi LJ, Kukko-Lukjanov TK.

Neurochem Int. 2004 Jul;45(1):1-10.

PMID:
15082216
33.

Kainate down-regulates a subset of GABAA receptor subunits expressed in cultured mouse cerebellar granule cells.

Martikainen IK, Lauk K, Möykkynen T, Holopainen IE, Korpi ER, Uusi-Oukari M.

Cerebellum. 2004;3(1):27-38.

PMID:
15072265
34.

Toxic effects of mining effluents on fish gills in a subarctic lake system in NW Russia.

Tkatcheva V, Hyvärinen H, Kukkonen J, Ryzhkov LP, Holopainen IJ.

Ecotoxicol Environ Saf. 2004 Mar;57(3):278-89.

PMID:
15041251
35.

Bisphenol A induces yolk-sac oedema and other adverse effects in landlocked salmon (Salmo salar m. sebago) yolk-sac fry.

Honkanen JO, Holopainen IJ, Kukkonen JV.

Chemosphere. 2004 Apr;55(2):187-96.

PMID:
14761691
37.

Selective changes in gamma-aminobutyric acid type A receptor subunits in the hippocampus in spontaneously seizing rats with chronic temporal lobe epilepsy.

Laurén HB, Pitkänen A, Nissinen J, Soini SL, Korpi ER, Holopainen IE.

Neurosci Lett. 2003 Sep 25;349(1):58-62.

PMID:
12946586
38.
39.

Asphyxia aggravates systemic hypotension but not pulmonary hypertension in piglets with meconium aspiration.

Aaltonen M, Soukka H, Halkola L, Jalonen J, Holopainen IE, Kero P, Kaapa PO.

Pediatr Res. 2003 Mar;53(3):473-8.

PMID:
12595597
40.

Sublethal energetic responses by Pisidium amnicum (Bivalvia) exposed to pentachlorophenol at two temperatures.

Heinonen J, Penttinen OP, Holopainen IJ, Kukkonen JV.

Environ Toxicol Chem. 2003 Feb;22(2):433-8.

PMID:
12558177
41.

[Angelman syndrome--from the phenotype of a developmental disorder to the genes].

Holopainen IE, Kokkonen H, Korpi ER.

Duodecim. 2001;117(4):383-7. Review. Finnish. No abstract available.

PMID:
12092380
42.

Focal and global cortical hypometabolism in patients with newly diagnosed infantile spasms.

Metsähonkala L, Gaily E, Rantala H, Salmi E, Valanne L, Aärimaa T, Liukkonen E, Holopainen I, Granström ML, Erkinjuntti M, Grönroos T, Sillanpää M.

Neurology. 2002 Jun 11;58(11):1646-51.

PMID:
12058093
43.

Bisphenol A accumulation in the freshwater clam Pisidium amnicum at low temperatures.

Heinonen J, Honkanen J, Kukkonen JV, Holopainen IJ.

Arch Environ Contam Toxicol. 2002 Jul;43(1):50-5.

PMID:
12045874
44.
45.

Changes in neurofilament protein-immunoreactivity after kainic acid treatment of organotypic hippocampal slice cultures.

Holopainen IE, Lauren HB, Romppanen A, Lopez-Picon FR.

J Neurosci Res. 2001 Nov 15;66(4):620-9.

PMID:
11746382
46.

Event-related desynchronization and synchronization during a memory task in children.

Krause CM, Salminen PA, Sillanmäki L, Holopainen IE.

Clin Neurophysiol. 2001 Dec;112(12):2233-40.

PMID:
11738193
47.
48.

Cognitive functions of adolescent childhood cancer survivors assessed by event-related potentials.

Lähteenmäki PM, Holopainen I, Krause CM, Helenius H, Salmi TT, Heikki LA.

Med Pediatr Oncol. 2001 Apr;36(4):442-50.

PMID:
11260567
49.

Early and late mismatch negativity elicited by words and speech-like stimuli in children.

Korpilahti P, Krause CM, Holopainen I, Lang AH.

Brain Lang. 2001 Mar;76(3):332-9.

PMID:
11247648
50.

Decreased binding of [11C]flumazenil in Angelman syndrome patients with GABA(A) receptor beta3 subunit deletions.

Holopainen IE, Metsähonkala EL, Kokkonen H, Parkkola RK, Manner TE, Någren K, Korpi ER.

Ann Neurol. 2001 Jan;49(1):110-3.

PMID:
11198279

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