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Items: 6

1.

MRP2 Inhibition by HIV Protease Inhibitors in Rat and Human Hepatocytes: A Quantitative Confocal Microscopy Study.

Holmstock N, Oorts M, Snoeys J, Annaert P.

Drug Metab Dispos. 2018 May;46(5):697-703. doi: 10.1124/dmd.117.079467. Epub 2018 Mar 9.

PMID:
29523599
2.

Confocal imaging with a fluorescent bile acid analogue closely mimicking hepatic taurocholate disposition.

De Bruyn T, Sempels W, Snoeys J, Holmstock N, Chatterjee S, Stieger B, Augustijns P, Hofkens J, Mizuno H, Annaert P.

J Pharm Sci. 2014 Jun;103(6):1872-81. doi: 10.1002/jps.23933. Epub 2014 Mar 20.

PMID:
24652646
3.

Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine.

Holmstock N, De Bruyn T, Bevernage J, Annaert P, Mols R, Tack J, Augustijns P.

Eur J Pharm Sci. 2013 Apr 11;49(1):27-32. doi: 10.1016/j.ejps.2013.01.012. Epub 2013 Feb 9.

PMID:
23402972
4.

PXR/CYP3A4-humanized mice for studying drug-drug interactions involving intestinal P-glycoprotein.

Holmstock N, Gonzalez FJ, Baes M, Annaert P, Augustijns P.

Mol Pharm. 2013 Mar 4;10(3):1056-62. doi: 10.1021/mp300512r. Epub 2013 Feb 19.

5.
6.

In situ intestinal perfusion in knockout mice demonstrates inhibition of intestinal p-glycoprotein by ritonavir causing increased darunavir absorption.

Holmstock N, Mols R, Annaert P, Augustijns P.

Drug Metab Dispos. 2010 Sep;38(9):1407-10. doi: 10.1124/dmd.110.032771. Epub 2010 Jun 15.

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