Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 59

1.

In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation.

Davis MT, Hillmer A, Holmes SE, Pietrzak RH, DellaGioia N, Nabulsi N, Matuskey D, Angarita GA, Carson RE, Krystal JH, Esterlis I.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11490-11495. doi: 10.1073/pnas.1818871116. Epub 2019 May 13. Erratum in: Proc Natl Acad Sci U S A. 2019 Jun 17;:.

PMID:
31085640
2.

Lower synaptic density is associated with depression severity and network alterations.

Holmes SE, Scheinost D, Finnema SJ, Naganawa M, Davis MT, DellaGioia N, Nabulsi N, Matuskey D, Angarita GA, Pietrzak RH, Duman RS, Sanacora G, Krystal JH, Carson RE, Esterlis I.

Nat Commun. 2019 Apr 4;10(1):1529. doi: 10.1038/s41467-019-09562-7.

3.

Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents.

Smith WS, Johnston DA, Holmes SE, Wensley HJ, Flavell SU, Flavell DJ.

Toxins (Basel). 2019 Feb 20;11(2). pii: E127. doi: 10.3390/toxins11020127.

4.

The TLR3 Agonist Poly Inosinic:Cytidylic Acid Significantly Augments the Therapeutic Activity of an Anti-CD7 Immunotoxin for Human T-cell Leukaemia.

Flavell DJ, Holmes SE, Warnes SL, Flavell SU.

Biomedicines. 2019 Feb 16;7(1). pii: E13. doi: 10.3390/biomedicines7010013.

5.

Cerebellar and prefrontal cortical alterations in PTSD: structural and functional evidence.

Holmes SE, Scheinost D, DellaGioia N, Davis MT, Matuskey D, Pietrzak RH, Hampson M, Krystal JH, Esterlis I.

Chronic Stress (Thousand Oaks). 2018 Jan-Dec;2. doi: 10.1177/2470547018786390. Epub 2018 Jul 6.

6.

Metabotropic Glutamatergic Receptor 5 and Stress Disorders: Knowledge Gained From Receptor Imaging Studies.

Esterlis I, Holmes SE, Sharma P, Krystal JH, DeLorenzo C.

Biol Psychiatry. 2018 Jul 15;84(2):95-105. doi: 10.1016/j.biopsych.2017.08.025. Epub 2017 Sep 19. Review.

7.

Metabotropic Glutamate Receptor 5 and Glutamate Involvement in Major Depressive Disorder: A Multimodal Imaging Study.

Abdallah CG, Hannestad J, Mason GF, Holmes SE, DellaGioia N, Sanacora G, Jiang L, Matuskey D, Satodiya R, Gasparini F, Lin X, Javitch J, Planeta B, Nabulsi N, Carson RE, Esterlis I.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Jul;2(5):449-456. doi: 10.1016/j.bpsc.2017.03.019. Epub 2017 Apr 6.

8.

Multimodal Investigation of Network Level Effects Using Intrinsic Functional Connectivity, Anatomical Covariance, and Structure-to-Function Correlations in Unmedicated Major Depressive Disorder.

Scheinost D, Holmes SE, DellaGioia N, Schleifer C, Matuskey D, Abdallah CG, Hampson M, Krystal JH, Anticevic A, Esterlis I.

Neuropsychopharmacology. 2018 Apr;43(5):1119-1127. doi: 10.1038/npp.2017.229. Epub 2017 Sep 25.

9.

Time-dependent neuronal changes associated with craving in opioid dependence: an fMRI study.

Murphy A, Lubman DI, McKie S, Bijral PS, Peters LA, Faiz Q, Holmes SE, Anderson IM, Deakin B, Elliott R.

Addict Biol. 2018 Sep;23(5):1168-1178. doi: 10.1111/adb.12554. Epub 2017 Sep 22.

10.

Elevated Translocator Protein in Anterior Cingulate in Major Depression and a Role for Inflammation in Suicidal Thinking: A Positron Emission Tomography Study.

Holmes SE, Hinz R, Conen S, Gregory CJ, Matthews JC, Anton-Rodriguez JM, Gerhard A, Talbot PS.

Biol Psychiatry. 2018 Jan 1;83(1):61-69. doi: 10.1016/j.biopsych.2017.08.005. Epub 2017 Aug 12.

PMID:
28939116
11.

Trajectories of depressive and anxiety symptoms in older adults: a 6-year prospective cohort study.

Holmes SE, Esterlis I, Mazure CM, Lim YY, Ames D, Rainey-Smith S, Fowler C, Ellis K, Martins RN, Salvado O, Doré V, Villemagne VL, Rowe CC, Laws SM, Masters CL, Pietrzak RH, Maruff P; Australian Imaging, Biomarkers and Lifestyle Research Group.

Int J Geriatr Psychiatry. 2018 Feb;33(2):405-413. doi: 10.1002/gps.4761. Epub 2017 Jul 24.

12.

Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence.

Holmes SE, Girgenti MJ, Davis MT, Pietrzak RH, DellaGioia N, Nabulsi N, Matuskey D, Southwick S, Duman RS, Carson RE, Krystal JH, Esterlis I; Traumatic Stress Brain Study Group.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8390-8395. doi: 10.1073/pnas.1701749114. Epub 2017 Jul 17. Erratum in: Proc Natl Acad Sci U S A. 2017 Sep 5;:.

13.

Membrane cholesterol is essential for triterpenoid saponin augmentation of a saporin-based immunotoxin directed against CD19 on human lymphoma cells.

Smith WS, Baker EJ, Holmes SE, Koster G, Hunt AN, Johnston DA, Flavell SU, Flavell DJ.

Biochim Biophys Acta Biomembr. 2017 May;1859(5):993-1007. doi: 10.1016/j.bbamem.2017.02.013. Epub 2017 Feb 21.

14.

Neurobiology of Chronic Stress-Related Psychiatric Disorders: Evidence from Molecular Imaging Studies.

Davis MT, Holmes SE, Pietrzak RH, Esterlis I.

Chronic Stress (Thousand Oaks). 2017 Jan-Dec;1. doi: 10.1177/2470547017710916. Epub 2017 Jun 22.

15.

β-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and Men.

Holmes SE, Esterlis I, Mazure CM, Lim YY, Ames D, Rainey-Smith S, Martins RN, Salvado O, Dore V, Villemagne VL, Rowe CC, Laws SM, Masters CL, Maruff P, Pietrzak RH; Australian Imaging, Biomarkers, Lifestyle Research Group.

Am J Geriatr Psychiatry. 2016 Dec;24(12):1191-1195. doi: 10.1016/j.jagp.2016.08.007. Epub 2016 Aug 17.

PMID:
27742526
16.

In vivo imaging of brain microglial activity in antipsychotic-free and medicated schizophrenia: a [11C](R)-PK11195 positron emission tomography study.

Holmes SE, Hinz R, Drake RJ, Gregory CJ, Conen S, Matthews JC, Anton-Rodriguez JM, Gerhard A, Talbot PS.

Mol Psychiatry. 2016 Dec;21(12):1672-1679. doi: 10.1038/mp.2016.180. Epub 2016 Oct 4.

PMID:
27698434
17.

Neuropathology and Cellular Pathogenesis of Spinocerebellar Ataxia Type 12.

O'Hearn EE, Hwang HS, Holmes SE, Rudnicki DD, Chung DW, Seixas AI, Cohen RL, Ross CA, Trojanowski JQ, Pletnikova O, Troncoso JC, Margolis RL.

Mov Disord. 2015 Nov;30(13):1813-1824. doi: 10.1002/mds.26348. Epub 2015 Sep 4.

18.

Triterpenoid saponin augmention of saporin-based immunotoxin cytotoxicity for human leukaemia and lymphoma cells is partially immunospecific and target molecule dependent.

Holmes SE, Bachran C, Fuchs H, Weng A, Melzig MF, Flavell SU, Flavell DJ.

Immunopharmacol Immunotoxicol. 2015 Feb;37(1):42-55. doi: 10.3109/08923973.2014.971964. Epub 2014 Oct 27.

PMID:
25347443
19.

Rare presentation of Rosai-Dorfman disease mimicking a cervical intramedullary spinal cord tumor.

El Molla M, Mahasneh T, Holmes SE, Al-Khawaja D.

World Neurosurg. 2014 Feb;81(2):442.e7-9. doi: 10.1016/j.wneu.2013.01.002. Epub 2013 Jan 4.

PMID:
23295635
20.

Pre- and postsynaptic serotonergic differences in males with extreme levels of impulsive aggression without callous unemotional traits: a positron emission tomography study using (11)C-DASB and (11)C-MDL100907.

Rylands AJ, Hinz R, Jones M, Holmes SE, Feldmann M, Brown G, McMahon AW, Talbot PS.

Biol Psychiatry. 2012 Dec 15;72(12):1004-11. doi: 10.1016/j.biopsych.2012.06.024. Epub 2012 Jul 25.

PMID:
22835812
21.

Loss of junctophilin-3 contributes to Huntington disease-like 2 pathogenesis.

Seixas AI, Holmes SE, Takeshima H, Pavlovich A, Sachs N, Pruitt JL, Silveira I, Ross CA, Margolis RL, Rudnicki DD.

Ann Neurol. 2012 Feb;71(2):245-57. doi: 10.1002/ana.22598.

PMID:
22367996
22.

Spinocerebellar Ataxia Type 12.

Margolis RL, Holmes SE, Srivastava AK, Mukherji M, Sinha KK.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2019.
2004 Oct 1 [updated 2011 Nov 17].

23.

Spinocerebellar ataxia type 12.

O'Hearn E, Holmes SE, Margolis RL.

Handb Clin Neurol. 2012;103:535-47. doi: 10.1016/B978-0-444-51892-7.00034-6. Review.

PMID:
21827912
24.

Missense mutations in the AFG3L2 proteolytic domain account for ∼1.5% of European autosomal dominant cerebellar ataxias.

Cagnoli C, Stevanin G, Brussino A, Barberis M, Mancini C, Margolis RL, Holmes SE, Nobili M, Forlani S, Padovan S, Pappi P, Zaros C, Leber I, Ribai P, Pugliese L, Assalto C, Brice A, Migone N, Dürr A, Brusco A.

Hum Mutat. 2010 Oct;31(10):1117-24. doi: 10.1002/humu.21342.

PMID:
20725928
25.

Long tandem repeats as a form of genomic copy number variation: structure and length polymorphism of a chromosome 5p repeat in control and schizophrenia populations.

Bruce HA, Sachs N, Rudnicki DD, Lin SG, Willour VL, Cowell JK, Conroy J, McQuaid DE, Rossi M, Gaile DP, Nowak NJ, Holmes SE, Sklar P, Ross CA, Delisi LE, Margolis RL.

Psychiatr Genet. 2009 Apr;19(2):64-71. doi: 10.1097/YPG.0b013e3283207ff6.

26.

Huntington's disease--like 2 is associated with CUG repeat-containing RNA foci.

Rudnicki DD, Holmes SE, Lin MW, Thornton CA, Ross CA, Margolis RL.

Ann Neurol. 2007 Mar;61(3):272-82.

PMID:
17387722
27.

A novel trinucleotide repeat expansion at chromosome 3q26.2 identified by a CAG/CTG repeat expansion detection array.

Holmes SE, Wentzell JS, Seixas AI, Callahan C, Silveira I, Ross CA, Margolis RL.

Hum Genet. 2006 Sep;120(2):193-200. Epub 2006 Jun 17.

PMID:
16783570
28.

Evidence of a common founder for SCA12 in the Indian population.

Bahl S, Virdi K, Mittal U, Sachdeva MP, Kalla AK, Holmes SE, O'Hearn E, Margolis RL, Jain S, Srivastava AK, Mukerji M.

Ann Hum Genet. 2005 Sep;69(Pt 5):528-34.

29.

A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder.

Sachs NA, Sawa A, Holmes SE, Ross CA, DeLisi LE, Margolis RL.

Mol Psychiatry. 2005 Aug;10(8):758-64.

PMID:
15940305
30.

Huntington's disease like-2: review and update.

Margolis RL, Rudnicki DD, Holmes SE.

Acta Neurol Taiwan. 2005 Mar;14(1):1-8. Review.

PMID:
15835282
31.

Huntington's Disease-like 2 (HDL2) in North America and Japan.

Margolis RL, Holmes SE, Rosenblatt A, Gourley L, O'Hearn E, Ross CA, Seltzer WK, Walker RH, Ashizawa T, Rasmussen A, Hayden M, Almqvist EW, Harris J, Fahn S, MacDonald ME, Mysore J, Shimohata T, Tsuji S, Potter N, Nakaso K, Adachi Y, Nakashima K, Bird T, Krause A, Greenstein P.

Ann Neurol. 2004 Nov;56(5):670-4. Erratum in: Ann Neurol. 2004 Dec;56(6):911.

PMID:
15468075
32.

Clinical signs and symptoms in a large hereditary spastic paraparesis pedigree with a novel spastin mutation.

Nicholas AP, O'Hearn E, Holmes SE, Chen DT, Margolis RL.

Mov Disord. 2004 Jun;19(6):641-8.

PMID:
15197701
33.

Detection of large pathogenic expansions in FRDA1, SCA10, and SCA12 genes using a simple fluorescent repeat-primed PCR assay.

Cagnoli C, Michielotto C, Matsuura T, Ashizawa T, Margolis RL, Holmes SE, Gellera C, Migone N, Brusco A.

J Mol Diagn. 2004 May;6(2):96-100.

34.

Novel CAG/CTG repeat expansion mutations do not contribute to the genetic risk for most cases of bipolar disorder or schizophrenia.

Tsutsumi T, Holmes SE, McInnis MG, Sawa A, Callahan C, DePaulo JR, Ross CA, DeLisi LE, Margolis RL.

Am J Med Genet B Neuropsychiatr Genet. 2004 Jan 1;124B(1):15-9.

PMID:
14681907
35.

Huntington's disease--like 2 can present as chorea-acanthocytosis.

Walker RH, Rasmussen A, Rudnicki D, Holmes SE, Alonso E, Matsuura T, Ashizawa T, Davidoff-Feldman B, Margolis RL.

Neurology. 2003 Oct 14;61(7):1002-4.

PMID:
14557581
36.

Why is SCA12 different from other SCAs?

Holmes SE, O'Hearn E, Margolis RL.

Cytogenet Genome Res. 2003;100(1-4):189-97. Review.

PMID:
14526180
37.

Trinucleotide repeat expansions in the junctophilin-3 gene are not found in Caucasian patients with a Huntington's disease-like phenotype.

Bauer I, Gencik M, Laccone F, Peters H, Weber BH, Feder EH, Weirich H, Morris-Rosendahl DJ, Rolfs A, Gencikova A, Bauer P, Wenning GK, Epplen JT, Holmes SE, Margolis RL, Ross CA, Riess O.

Ann Neurol. 2002 May;51(5):662. No abstract available.

PMID:
12112122
38.

Trinucleotide repeats in 202 families with ataxia: a small expanded (CAG)n allele at the SCA17 locus.

Silveira I, Miranda C, Guimarães L, Moreira MC, Alonso I, Mendonça P, Ferro A, Pinto-Basto J, Coelho J, Ferreirinha F, Poirier J, Parreira E, Vale J, Januário C, Barbot C, Tuna A, Barros J, Koide R, Tsuji S, Holmes SE, Margolis RL, Jardim L, Pandolfo M, Coutinho P, Sequeiros J.

Arch Neurol. 2002 Apr;59(4):623-9.

PMID:
11939898
39.

CAG/CTG repeat expansions at the Huntington's disease-like 2 locus are rare in Huntington's disease patients.

Stevanin G, Camuzat A, Holmes SE, Julien C, Sahloul R, Dodé C, Hahn-Barma V, Ross CA, Margolis RL, Durr A, Brice A.

Neurology. 2002 Mar 26;58(6):965-7.

PMID:
11914418
40.

A disorder similar to Huntington's disease is associated with a novel CAG repeat expansion.

Margolis RL, O'Hearn E, Rosenblatt A, Willour V, Holmes SE, Franz ML, Callahan C, Hwang HS, Troncoso JC, Ross CA.

Ann Neurol. 2001 Dec;50(6):373-80.

PMID:
11761463
41.

SCA12: an unusual mutation leads to an unusual spinocerebellar ataxia.

Holmes SE, Hearn EO, Ross CA, Margolis RL.

Brain Res Bull. 2001 Oct-Nov 1;56(3-4):397-403. Review.

PMID:
11719278
42.

A repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease-like 2.

Holmes SE, O'Hearn E, Rosenblatt A, Callahan C, Hwang HS, Ingersoll-Ashworth RG, Fleisher A, Stevanin G, Brice A, Potter NT, Ross CA, Margolis RL.

Nat Genet. 2001 Dec;29(4):377-8. Erratum in: Nat Genet 2002 Jan;30(1):123.

PMID:
11694876
43.

A disorder similar to Huntington's disease is associated with a novel CAG repeat expansion.

Margolis RL, O'Hearn E, Rosenblatt A, Willour V, Holmes SE, Franz ML, Callahan C, Hwang HS, Troncoso JC, Ross CA.

Ann Neurol. 2001 Sep;50(3):373-80. Corrected and republished in: Ann Neurol. 2001 Dec;50(6):373-80.

PMID:
11558794
44.

Prevalence, clinical manifestations, etiology, and treatment of depression in Parkinson's disease.

Slaughter JR, Slaughter KA, Nichols D, Holmes SE, Martens MP.

J Neuropsychiatry Clin Neurosci. 2001 Spring;13(2):187-96. Review.

PMID:
11449025
45.

SCA12 is a rare locus for autosomal dominant cerebellar ataxia: a study of an Indian family.

Fujigasaki H, Verma IC, Camuzat A, Margolis RL, Zander C, Lebre AS, Jamot L, Saxena R, Anand I, Holmes SE, Ross CA, Dürr A, Brice A.

Ann Neurol. 2001 Jan;49(1):117-21.

PMID:
11198281
46.

Risk factors in childhood that lead to the development of conduct disorder and antisocial personality disorder.

Holmes SE, Slaughter JR, Kashani J.

Child Psychiatry Hum Dev. 2001 Spring;31(3):183-93. Review.

PMID:
11196010
47.

SCA-12: Tremor with cerebellar and cortical atrophy is associated with a CAG repeat expansion.

O'Hearn E, Holmes SE, Calvert PC, Ross CA, Margolis RL.

Neurology. 2001 Feb 13;56(3):299-303.

PMID:
11171892
48.

Expansion of a novel CAG trinucleotide repeat in the 5' region of PPP2R2B is associated with SCA12.

Holmes SE, O'Hearn EE, McInnis MG, Gorelick-Feldman DA, Kleiderlein JJ, Callahan C, Kwak NG, Ingersoll-Ashworth RG, Sherr M, Sumner AJ, Sharp AH, Ananth U, Seltzer WK, Boss MA, Vieria-Saecker AM, Epplen JT, Riess O, Ross CA, Margolis RL.

Nat Genet. 1999 Dec;23(4):391-2. No abstract available.

PMID:
10581021
49.

Assessing parental utilization of the poison center: an emergency center-based survey.

Kelly NR, Kirkland RT, Holmes SE, Ellis MD, Delclos G, Kozinetz CA.

Clin Pediatr (Phila). 1997 Aug;36(8):467-73.

PMID:
9272321
50.

Disruption of the clathrin heavy chain-like gene (CLTCL) associated with features of DGS/VCFS: a balanced (21;22)(p12;q11) translocation.

Holmes SE, Riazi MA, Gong W, McDermid HE, Sellinger BT, Hua A, Chen F, Wang Z, Zhang G, Roe B, Gonzalez I, McDonald-McGinn DM, Zackai E, Emanuel BS, Budarf ML.

Hum Mol Genet. 1997 Mar;6(3):357-67.

PMID:
9147638

Supplemental Content

Loading ...
Support Center