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Items: 1 to 50 of 129

1.

Genetic Predisposition to Type 2 Diabetes and Risk of Subclinical Atherosclerosis and Cardiovascular Diseases Among 160,000 Chinese adults.

Gan W, Bragg F, Walters RG, Millwood IY, Lin K, Chen Y, Guo Y, Vaucher J, Bian Z, Bennett D, Lv J, Yu C, Mahajan A, Clarke RJ, Li L, Holmes MV, McCarthy MI, Chen Z; China Kadoorie Biobank Collaborative Group (members listed in the online supplemental materials).

Diabetes. 2019 Aug 9. pii: db190224. doi: 10.2337/db19-0224. [Epub ahead of print]

PMID:
31399431
2.

Commentary: Mendelian randomization and women's health.

Censin JC, Bovijn J, Holmes MV, Lindgren CM.

Int J Epidemiol. 2019 Jul 10. pii: dyz141. doi: 10.1093/ije/dyz141. [Epub ahead of print] No abstract available.

PMID:
31292646
3.

Variability in aspirin efficacy: all in the genes?

Baigent C, Holmes MV.

Eur Heart J. 2019 Jul 5. pii: ehz456. doi: 10.1093/eurheartj/ehz456. [Epub ahead of print] No abstract available.

PMID:
31280284
4.

Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study.

Carter AR, Gill D, Davies NM, Taylor AE, Tillmann T, Vaucher J, Wootton RE, Munafò MR, Hemani G, Malik R, Seshadri S, Woo D, Burgess S, Davey Smith G, Holmes MV, Tzoulaki I, Howe LD, Dehghan A.

BMJ. 2019 May 22;365:l1855. doi: 10.1136/bmj.l1855.

5.

The role of plasma microseminoprotein-beta in prostate cancer: an observational nested case-control and Mendelian randomization study in the European prospective investigation into cancer and nutrition.

Smith Byrne K, Appleby PN, Key TJ, Holmes MV, Fensom GK, Agudo A, Ardanaz E, Boeing H, Bueno-de-Mesquita HB, Chirlaque MD, Kaaks R, Larrañaga N, Palli D, Perez-Cornago A, Quirós JR, Ricceri F, Sánchez MJ, Tagliabue G, Tsilidis KK, Tumino R, Fortner RT, Ferrari P; PRACTICAL Consortium, Riboli E, Lilja H, Travis RC.

Ann Oncol. 2019 Apr 8. pii: mdz121. doi: 10.1093/annonc/mdz121. [Epub ahead of print]

6.

The association between the FTO gene variant and alcohol consumption and binge and problem drinking in different gene-environment background: The HAPIEE study.

Hubacek JA, Pikhart H, Peasey A, Malyutina S, Pajak A, Tamosiunas A, Voevoda M, Holmes MV, Bobak M.

Gene. 2019 Jul 30;707:30-35. doi: 10.1016/j.gene.2019.05.002. Epub 2019 May 2.

PMID:
31055022
7.

Direct Estimation of HDL-Mediated Cholesterol Efflux Capacity from Serum.

Kuusisto S, Holmes MV, Ohukainen P, Kangas AJ, Karsikas M, Tiainen M, Perola M, Salomaa V, Kettunen J, Ala-Korpela M.

Clin Chem. 2019 Aug;65(8):1042-1050. doi: 10.1373/clinchem.2018.299222. Epub 2019 Apr 17.

PMID:
30996052
8.

Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China.

Millwood IY, Walters RG, Mei XW, Guo Y, Yang L, Bian Z, Bennett DA, Chen Y, Dong C, Hu R, Zhou G, Yu B, Jia W, Parish S, Clarke R, Davey Smith G, Collins R, Holmes MV, Li L, Peto R, Chen Z; China Kadoorie Biobank Collaborative Group.

Lancet. 2019 May 4;393(10183):1831-1842. doi: 10.1016/S0140-6736(18)31772-0. Epub 2019 Apr 4.

9.

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.

Patel RS, Schmidt AF, Tragante V, McCubrey RO, Holmes MV, Howe LJ, Direk K, Åkerblom A, Leander K, Virani SS, Kaminski KA, Muehlschlegel JD, Dubé MP, Allayee H, Almgren P, Alver M, Baranova EV, Behlouli H, Boeckx B, Braund PS, Breitling LP, Delgado G, Duarte NE, Dufresne L, Eriksson N, Foco L, Gijsberts CM, Gong Y, Hartiala J, Heydarpour M, Hubacek JA, Kleber M, Kofink D, Kuukasjärvi P, Lee VV, Leiherer A, Lenzini PA, Levin D, Lyytikäinen LP, Martinelli N, Mons U, Nelson CP, Nikus K, Pilbrow AP, Ploski R, Sun YV, Tanck MWT, Tang WHW, Trompet S, van der Laan SW, van Setten J, Vilmundarson RO, Viviani Anselmi C, Vlachopoulou E, Boerwinkle E, Briguori C, Carlquist JF, Carruthers KF, Casu G, Deanfield J, Deloukas P, Dudbridge F, Fitzpatrick N, Gigante B, James S, Lokki ML, Lotufo PA, Marziliano N, Mordi IR, Muhlestein JB, Newton Cheh C, Pitha J, Saely CH, Samman-Tahhan A, Sandesara PB, Teren A, Timmis A, Van de Werf F, Wauters E, Wilde AAM, Ford I, Stott DJ, Algra A, Andreassi MG, Ardissino D, Arsenault BJ, Ballantyne CM, Bergmeijer TO, Bezzina CR, Body SC, Bogaty P, de Borst GJ, Brenner H, Burkhardt R, Carpeggiani C, Condorelli G, Cooper-DeHoff RM, Cresci S, de Faire U, Doughty RN, Drexel H, Engert JC, Fox KAA, Girelli D, Hagström E, Hazen SL, Held C, Hemingway H, Hoefer IE, Hovingh GK, Johnson JA, de Jong PA, Jukema JW, Kaczor MP, Kähönen M, Kettner J, Kiliszek M, Klungel OH, Lagerqvist B, Lambrechts D, Laurikka JO, Lehtimäki T, Lindholm D, Mahmoodi BK, Maitland-van der Zee AH, McPherson R, Melander O, Metspalu A, Pepinski W, Olivieri O, Opolski G, Palmer CN, Pasterkamp G, Pepine CJ, Pereira AC, Pilote L, Quyyumi AA, Richards AM, Sanak M, Scholz M, Siegbahn A, Sinisalo J, Smith JG, Spertus JA, Stewart AFR, Szczeklik W, Szpakowicz A, Ten Berg JM, Thanassoulis G, Thiery J, van der Graaf Y, Visseren FLJ, Waltenberger J; CARDIoGRAMPlusC4D Consortium, Van der Harst P, Tardif JC, Sattar N, Lang CC, Pare G, Brophy JM, Anderson JL, März W, Wallentin L, Cameron VA, Horne BD, Samani NJ, Hingorani AD, Asselbergs FW.

Circ Genom Precis Med. 2019 Apr;12(4):e002471. doi: 10.1161/CIRCGEN.119.002471. Epub 2019 Mar 21.

PMID:
30897348
10.

Subsequent Event Risk in Individuals With Established Coronary Heart Disease.

Patel RS, Tragante V, Schmidt AF, McCubrey RO, Holmes MV, Howe LJ, Direk K, Åkerblom A, Leander K, Virani SS, Kaminski KA, Muehlschlegel JD, Allayee H, Almgren P, Alver M, Baranova EV, Behloui H, Boeckx B, Braund PS, Breitling LP, Delgado G, Duarte NE, Dubé MP, Dufresne L, Eriksson N, Foco L, Scholz M, Gijsberts CM, Glinge C, Gong Y, Hartiala J, Heydarpour M, Hubacek JA, Kleber M, Kofink D, Kotti S, Kuukasjärvi P, Lee VV, Leiherer A, Lenzini PA, Levin D, Lyytikäinen LP, Martinelli N, Mons U, Nelson CP, Nikus K, Pilbrow AP, Ploski R, Sun YV, Tanck MWT, Tang WHW, Trompet S, van der Laan SW, Van Setten J, Vilmundarson RO, Viviani Anselmi C, Vlachopoulou E, Al Ali L, Boerwinkle E, Briguori C, Carlquist JF, Carruthers KF, Casu G, Deanfield J, Deloukas P, Dudbridge F, Engstrøm T, Fitzpatrick N, Fox K, Gigante B, James S, Lokki ML, Lotufo PA, Marziliano N, Mordi IR, Muhlestein JB, Newton-Cheh C, Pitha J, Saely CH, Samman-Tahhan A, Sandesara PB, Teren A, Timmis A, Van de Werf F, Wauters E, Wilde AAM, Ford I, Stott DJ, Algra A, Andreassi MG, Ardissino D, Arsenault BJ, Ballantyne CM, Bergmeijer TO, Bezzina CR, Body SC, Boersma EH, Bogaty P, Bots ML, Brenner H, Brugts JJ, Burkhardt R, Carpeggiani C, Condorelli G, Cooper-DeHoff RM, Cresci S, Danchin N, de Faire U, Doughty RN, Drexel H, Engert JC, Fox KAA, Girelli D, Grobbee DE, Hagström E, Hazen SL, Held C, Hemingway H, Hoefer IE, Hovingh GK, Jabbari R, Johnson JA, Jukema JW, Kaczor MP, Kähönen M, Kettner J, Kiliszek M, Klungel OH, Lagerqvist B, Lambrechts D, Laurikka JO, Lehtimäki T, Lindholm D, Mahmoodi BK, Maitland-van der Zee AH, McPherson R, Melander O, Metspalu A, Niemcunowicz-Janica A, Olivieri O, Opolski G, Palmer CN, Pasterkamp G, Pepine CJ, Pereira AC, Pilote L, Quyyumi AA, Richards AM, Sanak M, Siegbahn A, Simon T, Sinisalo J, Smith JG, Spertus JA, Stender S, Stewart AFR, Szczeklik W, Szpakowicz A, Tardif JC, Ten Berg JM, Tfelt-Hansen J, Thanassoulis G, Thiery J, Torp-Pedersen C, van der Graaf Y, Visseren FLJ, Waltenberger J, Weeke PE, Van der Harst P, Lang CC, Sattar N, Cameron VA, Anderson JL, Brophy JM, Pare G, Horne BD, März W, Wallentin L, Samani NJ, Hingorani AD, Asselbergs FW.

Circ Genom Precis Med. 2019 Apr;12(4):e002470. doi: 10.1161/CIRCGEN.119.002470. Epub 2019 Mar 21.

PMID:
30896328
11.

Human Genetics and Drug Development.

Holmes MV.

N Engl J Med. 2019 Mar 14;380(11):1076-1079. doi: 10.1056/NEJMe1901565. No abstract available.

PMID:
30865805
12.

Meta-analysis and Mendelian randomization: A review.

Bowden J, Holmes MV.

Res Synth Methods. 2019 Mar 12. doi: 10.1002/jrsm.1346. [Epub ahead of print] Review.

PMID:
30861319
13.

A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome.

Wiberg A, Ng M, Schmid AB, Smillie RW, Baskozos G, Holmes MV, Künnapuu K, Mägi R, Bennett DL, Furniss D.

Nat Commun. 2019 Mar 4;10(1):1030. doi: 10.1038/s41467-019-08993-6.

14.

Cholesteryl Ester Transfer Protein Inhibition for Preventing Cardiovascular Events: JACC Review Topic of the Week.

Armitage J, Holmes MV, Preiss D.

J Am Coll Cardiol. 2019 Feb 5;73(4):477-487. doi: 10.1016/j.jacc.2018.10.072. Review.

15.

What is 'LDL cholesterol'?

Holmes MV, Ala-Korpela M.

Nat Rev Cardiol. 2019 Apr;16(4):197-198. doi: 10.1038/s41569-019-0157-6. No abstract available.

PMID:
30700860
16.

Adiposity in relation to risks of fatty liver, cirrhosis and liver cancer: a prospective study of 0.5 million Chinese adults.

Pang Y, Kartsonaki C, Turnbull I, Guo Y, Chen Y, Clarke R, Bian Z, Bragg F, Millwood IY, Yang L, Huang Y, Yang Y, Zhang X, Chen J, Li L, Holmes MV, Chen Z.

Sci Rep. 2019 Jan 28;9(1):785. doi: 10.1038/s41598-018-36460-7.

17.

Can Mendelian Randomization Shift into Reverse Gear?

Holmes MV, Davey Smith G.

Clin Chem. 2019 Mar;65(3):363-366. doi: 10.1373/clinchem.2018.296806. Epub 2019 Jan 28. No abstract available.

PMID:
30692117
18.

Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics.

Tynkkynen T, Wang Q, Ekholm J, Anufrieva O, Ohukainen P, Vepsäläinen J, Männikkö M, Keinänen-Kiukaanniemi S, Holmes MV, Goodwin M, Ring S, Chambers JC, Kooner J, Järvelin MR, Kettunen J, Hill M, Davey Smith G, Ala-Korpela M.

Int J Epidemiol. 2019 Jan 25. doi: 10.1093/ije/dyy287. [Epub ahead of print]

19.

Central adiposity in relation to risk of liver cancer in Chinese adults: A prospective study of 0.5 million people.

Pang Y, Kartsonaki C, Guo Y, Chen Y, Yang L, Bian Z, Bragg F, Millwood IY, Yu C, Lv J, Chen J, Li L, Holmes MV, Chen Z.

Int J Cancer. 2019 Sep 1;145(5):1245-1253. doi: 10.1002/ijc.32148. Epub 2019 Feb 13.

PMID:
30665257
20.

GWAS Identifies Risk Locus for Erectile Dysfunction and Implicates Hypothalamic Neurobiology and Diabetes in Etiology.

Bovijn J, Jackson L, Censin J, Chen CY, Laisk T, Laber S, Ferreira T, Pulit SL, Glastonbury CA, Smoller JW, Harrison JW, Ruth KS, Beaumont RN, Jones SE, Tyrrell J, Wood AR, Weedon MN, Mägi R, Neale B, Lindgren CM, Murray A, Holmes MV.

Am J Hum Genet. 2019 Jan 3;104(1):157-163. doi: 10.1016/j.ajhg.2018.11.004. Epub 2018 Dec 21.

21.

A review of lifestyle, metabolic risk factors, and blood-based biomarkers for early diagnosis of pancreatic ductal adenocarcinoma.

Pang Y, Holmes MV, Chen Z, Kartsonaki C.

J Gastroenterol Hepatol. 2019 Feb;34(2):330-345. doi: 10.1111/jgh.14576. Epub 2019 Jan 17. Review.

22.

Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment.

Sliz E, Kettunen J, Holmes MV, Williams CO, Boachie C, Wang Q, Männikkö M, Sebert S, Walters R, Lin K, Millwood IY, Clarke R, Li L, Rankin N, Welsh P, Delles C, Jukema JW, Trompet S, Ford I, Perola M, Salomaa V, Järvelin MR, Chen Z, Lawlor DA, Ala-Korpela M, Danesh J, Davey Smith G, Sattar N, Butterworth A, Würtz P.

Circulation. 2018 Nov 27;138(22):2499-2512. doi: 10.1161/CIRCULATIONAHA.118.034942. Epub 2018 Aug 15.

PMID:
30524137
23.

GWAS identifies 14 loci for device-measured physical activity and sleep duration.

Doherty A, Smith-Byrne K, Ferreira T, Holmes MV, Holmes C, Pulit SL, Lindgren CM.

Nat Commun. 2018 Dec 10;9(1):5257. doi: 10.1038/s41467-018-07743-4.

24.

Metabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment

Sliz E, Kettunen J, Holmes MV, Williams CO, Boachie C, Wang Q, Männikkö M, Sebert S, Walters R, Lin K, Millwood LY, Clarke R, Li L, Rankin N, Welsh P, Delles C, Jukema JW, Trompet S, Ford I, Perola M, Salomaa V, Järvelin MR, Chen Z, Lawlor DA, Ala-Korpela M, Danesh J, Smith GD, Sattar N, Butterworth A, Würtz P.

Circulation. 2018 Nov 27;138(22):2499–2512.

25.

Research digest: genetics in cardiometabolic disease.

Sattar N, Holmes MV, Preiss D.

Lancet Diabetes Endocrinol. 2018 Dec;6(12):922. doi: 10.1016/S2213-8587(18)30318-8. No abstract available.

PMID:
30470341
26.

Leukocyte telomere length and risk of coronary heart disease and stroke mortality: prospective evidence from a Russian cohort.

Stefler D, Malyutina S, Maximov V, Orlov P, Ivanoschuk D, Nikitin Y, Gafarov V, Ryabikov A, Voevoda M, Bobak M, Holmes MV.

Sci Rep. 2018 Nov 9;8(1):16627. doi: 10.1038/s41598-018-35122-y.

27.

Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study.

Bell JA, Carslake D, Wade KH, Richmond RC, Langdon RJ, Vincent EE, Holmes MV, Timpson NJ, Davey Smith G.

PLoS Med. 2018 Aug 28;15(8):e1002641. doi: 10.1371/journal.pmed.1002641. eCollection 2018 Aug.

28.

Metabolic and lifestyle risk factors for acute pancreatitis in Chinese adults: A prospective cohort study of 0.5 million people.

Pang Y, Kartsonaki C, Turnbull I, Guo Y, Yang L, Bian Z, Chen Y, Millwood IY, Bragg F, Gong W, Xu Q, Kang Q, Chen J, Li L, Holmes MV, Chen Z.

PLoS Med. 2018 Aug 1;15(8):e1002618. doi: 10.1371/journal.pmed.1002618. eCollection 2018 Aug.

29.

Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians.

Davies NM, Holmes MV, Davey Smith G.

BMJ. 2018 Jul 12;362:k601. doi: 10.1136/bmj.k601. No abstract available.

30.

Diabetes, plasma glucose and incidence of colorectal cancer in Chinese adults: a prospective study of 0.5 million people.

Pang Y, Kartsonaki C, Guo Y, Chen Y, Yang L, Bian Z, Bragg F, Millwood IY, Shen L, Zhou S, Liu J, Chen J, Li L, Holmes MV, Chen Z.

J Epidemiol Community Health. 2018 Oct;72(10):919-925. doi: 10.1136/jech-2018-210651. Epub 2018 Jul 3.

31.

Adiposity and risks of colorectal and small intestine cancer in Chinese adults: a prospective study of 0.5 million people.

Pang Y, Kartsonaki C, Guo Y, Chen Y, Yang L, Bian Z, Bragg F, Millwood IY, Mao E, Li Y, Shi L, Chen J, Li L, Holmes MV, Chen Z.

Br J Cancer. 2018 Jul;119(2):248-250. doi: 10.1038/s41416-018-0124-8. Epub 2018 Jun 6.

32.

Adiposity and risk of ischaemic and haemorrhagic stroke in 0·5 million Chinese men and women: a prospective cohort study.

Chen Z, Iona A, Parish S, Chen Y, Guo Y, Bragg F, Yang L, Bian Z, Holmes MV, Lewington S, Lacey B, Gao R, Liu F, Zhang Z, Chen J, Walters RG, Collins R, Clarke R, Peto R, Li L; China Kadoorie Biobank collaborative group.

Lancet Glob Health. 2018 Jun;6(6):e630-e640. doi: 10.1016/S2214-109X(18)30216-X.

33.

Diabetes, Plasma Glucose, and Incidence of Fatty Liver, Cirrhosis, and Liver Cancer: A Prospective Study of 0.5 Million People.

Pang Y, Kartsonaki C, Turnbull I, Guo Y, Clarke R, Chen Y, Bragg F, Yang L, Bian Z, Millwood IY, Hao J, Han X, Zang Y, Chen J, Li L, Holmes MV, Chen Z.

Hepatology. 2018 Oct;68(4):1308-1318. doi: 10.1002/hep.30083.

34.

Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.

Lu L, Bennett DA, Millwood IY, Parish S, McCarthy MI, Mahajan A, Lin X, Bragg F, Guo Y, Holmes MV, Afzal S, Nordestgaard BG, Bian Z, Hill M, Walters RG, Li L, Chen Z, Clarke R.

PLoS Med. 2018 May 2;15(5):e1002566. doi: 10.1371/journal.pmed.1002566. eCollection 2018 May.

35.

Problems in interpreting and using GWAS of conditional phenotypes illustrated by 'alcohol GWAS'.

Holmes MV, Davey Smith G.

Mol Psychiatry. 2019 Feb;24(2):167-168. doi: 10.1038/s41380-018-0037-1. Epub 2018 Mar 8. No abstract available.

36.

Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke.

Holmes MV, Millwood IY, Kartsonaki C, Hill MR, Bennett DA, Boxall R, Guo Y, Xu X, Bian Z, Hu R, Walters RG, Chen J, Ala-Korpela M, Parish S, Clarke RJ, Peto R, Collins R, Li L, Chen Z; China Kadoorie Biobank Collaborative Group.

J Am Coll Cardiol. 2018 Feb 13;71(6):620-632. doi: 10.1016/j.jacc.2017.12.006.

37.

Challenges in Interpreting Multivariable Mendelian Randomization: Might "Good Cholesterol" Be Good After All?

Holmes MV, Davey Smith G.

Am J Kidney Dis. 2018 Feb;71(2):149-153. doi: 10.1053/j.ajkd.2017.10.006. No abstract available.

PMID:
29389382
38.

Associations of General and Central Adiposity With Incident Diabetes in Chinese Men and Women.

Bragg F, Tang K, Guo Y, Iona A, Du H, Holmes MV, Bian Z, Kartsonaki C, Chen Y, Yang L, Sun Q, Dong C, Chen J, Collins R, Peto R, Li L, Chen Z; China Kadoorie Biobank (CKB) Collaborative Group.

Diabetes Care. 2018 Mar;41(3):494-502. doi: 10.2337/dc17-1852. Epub 2018 Jan 3.

39.

Smoking, alcohol, and diet in relation to risk of pancreatic cancer in China: a prospective study of 0.5 million people.

Pang Y, Holmes MV, Guo Y, Yang L, Bian Z, Chen Y, Iona A, Millwood IY, Bragg F, Chen J, Li L, Kartsonaki C, Chen Z.

Cancer Med. 2018 Jan;7(1):229-239. doi: 10.1002/cam4.1261. Epub 2017 Dec 22.

40.

Genetic Association of Lipids and Lipid Drug Targets With Abdominal Aortic Aneurysm: A Meta-analysis.

Harrison SC, Holmes MV, Burgess S, Asselbergs FW, Jones GT, Baas AF, van 't Hof FN, de Bakker PIW, Blankensteijn JD, Powell JT, Saratzis A, de Borst GJ, Swerdlow DI, van der Graaf Y, van Rij AM, Carey DJ, Elmore JR, Tromp G, Kuivaniemi H, Sayers RD, Samani NJ, Bown MJ, Humphries SE.

JAMA Cardiol. 2018 Jan 1;3(1):26-33. doi: 10.1001/jamacardio.2017.4293.

41.

Association of CETP Gene Variants With Risk for Vascular and Nonvascular Diseases Among Chinese Adults.

Millwood IY, Bennett DA, Holmes MV, Boxall R, Guo Y, Bian Z, Yang L, Sansome S, Chen Y, Du H, Yu C, Hacker A, Reilly DF, Tan Y, Hill MR, Chen J, Peto R, Shen H, Collins R, Clarke R, Li L, Walters RG, Chen Z; China Kadoorie Biobank Collaborative Group.

JAMA Cardiol. 2018 Jan 1;3(1):34-43. doi: 10.1001/jamacardio.2017.4177. Erratum in: JAMA Cardiol. 2018 Jan 1;3(1):90.

42.

Correcting the Standard Errors of 2-Stage Residual Inclusion Estimators for Mendelian Randomization Studies.

Palmer TM, Holmes MV, Keating BJ, Sheehan NA.

Am J Epidemiol. 2017 Nov 1;186(9):1104-1114. doi: 10.1093/aje/kwx175.

43.

Genetic Support for a Causal Role of Insulin Resistance on Circulating Branched-Chain Amino Acids and Inflammation.

Wang Q, Holmes MV, Davey Smith G, Ala-Korpela M.

Diabetes Care. 2017 Dec;40(12):1779-1786. doi: 10.2337/dc17-1642. Epub 2017 Oct 18.

44.

Bone mineral density and risk of type 2 diabetes and coronary heart disease: A Mendelian randomization study.

Gan W, Clarke RJ, Mahajan A, Kulohoma B, Kitajima H, Robertson NR, Rayner NW, Walters RG, Holmes MV, Chen Z, McCarthy MI.

Wellcome Open Res. 2017 Aug 22;2:68. doi: 10.12688/wellcomeopenres.12288.1. eCollection 2017.

45.

Impact of Selection Bias on Estimation of Subsequent Event Risk.

Hu YJ, Schmidt AF, Dudbridge F, Holmes MV, Brophy JM, Tragante V, Li Z, Liao P, Quyyumi AA, McCubrey RO, Horne BD, Hingorani AD, Asselbergs FW, Patel RS, Long Q; The GENIUS-CHD Consortium.

Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001616. doi: 10.1161/CIRCGENETICS.116.001616.

46.

Dyslipidaemia: Revealing the effect of CETP inhibition in cardiovascular disease.

Holmes MV, Smith GD.

Nat Rev Cardiol. 2017 Nov;14(11):635-636. doi: 10.1038/nrcardio.2017.156. Epub 2017 Oct 5. Review. No abstract available.

47.

Genetic and epigenetic studies of adiposity and cardiometabolic disease.

Holmes MV, Pulit SL, Lindgren CM.

Genome Med. 2017 Sep 18;9(1):82. doi: 10.1186/s13073-017-0474-5. Review.

48.

Young adulthood and adulthood adiposity in relation to incidence of pancreatic cancer: a prospective study of 0.5 million Chinese adults and a meta-analysis.

Pang Y, Holmes MV, Kartsonaki C, Guo Y, Yang L, Bian Z, Chen Y, Bragg F, Iona A, Millwood IY, Chen J, Li L, Chen Z.

J Epidemiol Community Health. 2017 Nov;71(11):1059-1067. doi: 10.1136/jech-2017-208895. Epub 2017 Sep 12.

49.

Education and coronary heart disease: mendelian randomisation study.

Tillmann T, Vaucher J, Okbay A, Pikhart H, Peasey A, Kubinova R, Pajak A, Tamosiunas A, Malyutina S, Hartwig FP, Fischer K, Veronesi G, Palmer T, Bowden J, Davey Smith G, Bobak M, Holmes MV.

BMJ. 2017 Aug 30;358:j3542. doi: 10.1136/bmj.j3542.

50.

Association of Body Mass Index With Cardiometabolic Disease in the UK Biobank: A Mendelian Randomization Study.

Lyall DM, Celis-Morales C, Ward J, Iliodromiti S, Anderson JJ, Gill JMR, Smith DJ, Ntuk UE, Mackay DF, Holmes MV, Sattar N, Pell JP.

JAMA Cardiol. 2017 Aug 1;2(8):882-889. doi: 10.1001/jamacardio.2016.5804.

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