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Items: 1 to 50 of 168

1.

Identification of H209 as Essential for pH 8-Triggered Receptor-Independent Syncytium Formation by S Protein of Mouse Hepatitis Virus A59.

Li P, Shan Y, Zheng W, Ou X, Mi D, Mu Z, Holmes KV, Qian Z.

J Virol. 2018 May 14;92(11). pii: e00209-18. doi: 10.1128/JVI.00209-18. Print 2018 Jun 1.

2.

Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor.

Peng G, Yang Y, Pasquarella JR, Xu L, Qian Z, Holmes KV, Li F.

J Biol Chem. 2017 Feb 10;292(6):2174-2181. doi: 10.1074/jbc.M116.764266. Epub 2016 Dec 29.

3.

Identification of the Fusion Peptide-Containing Region in Betacoronavirus Spike Glycoproteins.

Ou X, Zheng W, Shan Y, Mu Z, Dominguez SR, Holmes KV, Qian Z.

J Virol. 2016 May 27;90(12):5586-5600. doi: 10.1128/JVI.00015-16. Print 2016 Jun 15.

4.

Platform technology to generate broadly cross-reactive antibodies to α-helical epitopes in hemagglutinin proteins from influenza A viruses.

Jiang Z, Gera L, Mant CT, Hirsch B, Yan Z, Shortt JA, Pollock DD, Qian Z, Holmes KV, Hodges RS.

Biopolymers. 2016 Mar;106(2):144-159. doi: 10.1002/bip.22808.

PMID:
26799790
5.

Identification of the Receptor-Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1.

Qian Z, Ou X, Góes LG, Osborne C, Castano A, Holmes KV, Dominguez SR.

J Virol. 2015 Sep;89(17):8816-27. doi: 10.1128/JVI.03737-14. Epub 2015 Jun 17.

6.

Molecular phylogeny of hantaviruses harbored by insectivorous bats in Côte d'Ivoire and Vietnam.

Gu SH, Lim BK, Kadjo B, Arai S, Kim JA, Nicolas V, Lalis A, Denys C, Cook JA, Dominguez SR, Holmes KV, Urushadze L, Sidamonidze K, Putkaradze D, Kuzmin IV, Kosoy MY, Song JW, Yanagihara R.

Viruses. 2014 Apr 29;6(5):1897-910. doi: 10.3390/v6051897.

7.

Isolation, propagation, genome analysis and epidemiology of HKU1 betacoronaviruses.

Dominguez SR, Shrivastava S, Berglund A, Qian Z, Góes LG, Halpin RA, Fedorova N, Ransier A, Weston PA, Durigon EL, Jerez JA, Robinson CC, Town CD, Holmes KV.

J Gen Virol. 2014 Apr;95(Pt 4):836-48. doi: 10.1099/vir.0.059832-0. Epub 2014 Jan 6.

8.

Role of the spike glycoprotein of human Middle East respiratory syndrome coronavirus (MERS-CoV) in virus entry and syncytia formation.

Qian Z, Dominguez SR, Holmes KV.

PLoS One. 2013 Oct 3;8(10):e76469. doi: 10.1371/journal.pone.0076469. eCollection 2013.

9.

Innate immune response of human alveolar type II cells infected with severe acute respiratory syndrome-coronavirus.

Qian Z, Travanty EA, Oko L, Edeen K, Berglund A, Wang J, Ito Y, Holmes KV, Mason RJ.

Am J Respir Cell Mol Biol. 2013 Jun;48(6):742-8. doi: 10.1165/rcmb.2012-0339OC.

10.
11.

The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction.

Chen L, Chen Z, Baker K, Halvorsen EM, da Cunha AP, Flak MB, Gerber G, Huang YH, Hosomi S, Arthur JC, Dery KJ, Nagaishi T, Beauchemin N, Holmes KV, Ho JW, Shively JE, Jobin C, Onderdonk AB, Bry L, Weiner HL, Higgins DE, Blumberg RS.

Immunity. 2012 Nov 16;37(5):930-46. doi: 10.1016/j.immuni.2012.07.016. Epub 2012 Nov 1.

12.

Crystal structure of bovine coronavirus spike protein lectin domain.

Peng G, Xu L, Lin YL, Chen L, Pasquarella JR, Holmes KV, Li F.

J Biol Chem. 2012 Dec 7;287(50):41931-8. doi: 10.1074/jbc.M112.418210. Epub 2012 Oct 22.

13.

Genomic analysis of 16 Colorado human NL63 coronaviruses identifies a new genotype, high sequence diversity in the N-terminal domain of the spike gene and evidence of recombination.

Dominguez SR, Sims GE, Wentworth DE, Halpin RA, Robinson CC, Town CD, Holmes KV.

J Gen Virol. 2012 Nov;93(Pt 11):2387-98. doi: 10.1099/vir.0.044628-0. Epub 2012 Jul 25.

14.

Infection of human alveolar macrophages by human coronavirus strain 229E.

Funk CJ, Wang J, Ito Y, Travanty EA, Voelker DR, Holmes KV, Mason RJ.

J Gen Virol. 2012 Mar;93(Pt 3):494-503. doi: 10.1099/vir.0.038414-0. Epub 2011 Nov 16.

15.

Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation.

Lu SX, Kappel LW, Charbonneau-Allard AM, Atallah R, Holland AM, Turbide C, Hubbard VM, Rotolo JA, Smith M, Suh D, King C, Rao UK, Yim N, Bautista JL, Jenq RR, Penack O, Na IK, Liu C, Murphy G, Alpdogan O, Blumberg RS, Macian F, Holmes KV, Beauchemin N, van den Brink MR.

PLoS One. 2011;6(7):e21611. doi: 10.1371/journal.pone.0021611. Epub 2011 Jul 6.

16.

Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor.

Peng G, Sun D, Rajashankar KR, Qian Z, Holmes KV, Li F.

Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10696-701. doi: 10.1073/pnas.1104306108. Epub 2011 Jun 13.

17.

Alphacoronaviruses in New World bats: prevalence, persistence, phylogeny, and potential for interaction with humans.

Osborne C, Cryan PM, O'Shea TJ, Oko LM, Ndaluka C, Calisher CH, Berglund AD, Klavetter ML, Bowen RA, Holmes KV, Dominguez SR.

PLoS One. 2011 May 12;6(5):e19156. doi: 10.1371/journal.pone.0019156.

18.

Role of mouse hepatitis virus (MHV) receptor murine CEACAM1 in the resistance of mice to MHV infection: studies of mice with chimeric mCEACAM1a and mCEACAM1b.

Hirai A, Ohtsuka N, Ikeda T, Taniguchi R, Blau D, Nakagaki K, Miura HS, Ami Y, Yamada YK, Itohara S, Holmes KV, Taguchi F.

J Virol. 2010 Jul;84(13):6654-66. doi: 10.1128/JVI.02680-09. Epub 2010 Apr 21.

19.

Rat respiratory coronavirus infection: replication in airway and alveolar epithelial cells and the innate immune response.

Funk CJ, Manzer R, Miura TA, Groshong SD, Ito Y, Travanty EA, Leete J, Holmes KV, Mason RJ.

J Gen Virol. 2009 Dec;90(Pt 12):2956-64. doi: 10.1099/vir.0.014282-0. Epub 2009 Sep 9.

20.

Host-pathogen interactions during coronavirus infection of primary alveolar epithelial cells.

Miura TA, Holmes KV.

J Leukoc Biol. 2009 Nov;86(5):1145-51. doi: 10.1189/jlb.0209078. Epub 2009 Jul 28. Review.

21.

Detection of four human coronaviruses in respiratory infections in children: a one-year study in Colorado.

Dominguez SR, Robinson CC, Holmes KV.

J Med Virol. 2009 Sep;81(9):1597-604. doi: 10.1002/jmv.21541.

22.

Expression and characterization of recombinant S2 subunit of SARS-coronavirus S fusion protein.

Yan Z, Holmes KV, Hodges RS.

Adv Exp Med Biol. 2009;611:153-4. No abstract available.

PMID:
19400136
23.

Role of Ceacam1 in VEGF induced vasculogenesis of murine embryonic stem cell-derived embryoid bodies in 3D culture.

Gu A, Tsark W, Holmes KV, Shively JE.

Exp Cell Res. 2009 Jun 10;315(10):1668-82. doi: 10.1016/j.yexcr.2009.02.026. Epub 2009 Mar 10.

24.

Peptide nanoparticles as novel immunogens: design and analysis of a prototypic severe acute respiratory syndrome vaccine.

Pimentel TA, Yan Z, Jeffers SA, Holmes KV, Hodges RS, Burkhard P.

Chem Biol Drug Des. 2009 Jan;73(1):53-61. doi: 10.1111/j.1747-0285.2008.00746.x.

25.

Multiplex MassTag-PCR for respiratory pathogens in pediatric nasopharyngeal washes negative by conventional diagnostic testing shows a high prevalence of viruses belonging to a newly recognized rhinovirus clade.

Dominguez SR, Briese T, Palacios G, Hui J, Villari J, Kapoor V, Tokarz R, Glodé MP, Anderson MS, Robinson CC, Holmes KV, Lipkin WI.

J Clin Virol. 2008 Oct;43(2):219-22. doi: 10.1016/j.jcv.2008.06.007.

26.

Global distribution of novel rhinovirus genotype.

Briese T, Renwick N, Venter M, Jarman RG, Ghosh D, Köndgen S, Shrestha SK, Hoegh AM, Casas I, Adjogoua EV, Akoua-Koffi C, Myint KS, Williams DT, Chidlow G, van den Berg R, Calvo C, Koch O, Palacios G, Kapoor V, Villari J, Dominguez SR, Holmes KV, Harnett G, Smith D, Mackenzie JS, Ellerbrok H, Schweiger B, Schønning K, Chadha MS, Leendertz FH, Mishra AC, Gibbons RV, Holmes EC, Lipkin WI.

Emerg Infect Dis. 2008 Jun;14(6):944-7. doi: 10.3201/eid1406.080271.

27.

CD13 is a novel mediator of monocytic/endothelial cell adhesion.

Mina-Osorio P, Winnicka B, O'Conor C, Grant CL, Vogel LK, Rodriguez-Pinto D, Holmes KV, Ortega E, Shapiro LH.

J Leukoc Biol. 2008 Aug;84(2):448-59. doi: 10.1189/jlb.1107802. Epub 2008 May 21.

28.

Detection of group 1 coronaviruses in bats in North America.

Dominguez SR, O'Shea TJ, Oko LM, Holmes KV.

Emerg Infect Dis. 2007 Sep;13(9):1295-300. doi: 10.3201/eid1309.070491.

29.

Aromatic amino acids in the juxtamembrane domain of severe acute respiratory syndrome coronavirus spike glycoprotein are important for receptor-dependent virus entry and cell-cell fusion.

Howard MW, Travanty EA, Jeffers SA, Smith MK, Wennier ST, Thackray LB, Holmes KV.

J Virol. 2008 Mar;82(6):2883-94. doi: 10.1128/JVI.01805-07. Epub 2008 Jan 16.

30.

SARS-CoV replicates in primary human alveolar type II cell cultures but not in type I-like cells.

Mossel EC, Wang J, Jeffers S, Edeen KE, Wang S, Cosgrove GP, Funk CJ, Manzer R, Miura TA, Pearson LD, Holmes KV, Mason RJ.

Virology. 2008 Mar 1;372(1):127-35. Epub 2007 Nov 26.

31.

The spike glycoprotein of murine coronavirus MHV-JHM mediates receptor-independent infection and spread in the central nervous systems of Ceacam1a-/- Mice.

Miura TA, Travanty EA, Oko L, Bielefeldt-Ohmann H, Weiss SR, Beauchemin N, Holmes KV.

J Virol. 2008 Jan;82(2):755-63. Epub 2007 Nov 14.

32.

Rat coronaviruses infect rat alveolar type I epithelial cells and induce expression of CXC chemokines.

Miura TA, Wang J, Holmes KV, Mason RJ.

Virology. 2007 Dec 20;369(2):288-98. Epub 2007 Sep 5.

33.

Blinded case-control study of the relationship between human coronavirus NL63 and Kawasaki syndrome.

Dominguez SR, Anderson MS, Glodé MP, Robinson CC, Holmes KV.

J Infect Dis. 2006 Dec 15;194(12):1697-701. Epub 2006 Nov 2.

PMID:
17109341
34.
35.

Rat coronavirus infection of primary rat alveolar epithelial cells.

Miura TA, Wang J, Mason RJ, Holmes KV.

Adv Exp Med Biol. 2006;581:351-6. No abstract available.

PMID:
17037558
36.

Dissection of the fusion machine of SARS-coronavirus.

Howard MW, Tripet B, Jobling MG, Holmes RK, Holmes KV, Hodges RS.

Adv Exp Med Biol. 2006;581:319-22. No abstract available.

PMID:
17037552
37.

Molecular interactions of group 1 coronaviruses with feline APN.

Tusell SM, Holmes KV.

Adv Exp Med Biol. 2006;581:289-91. No abstract available.

PMID:
17037545
38.

Human angiotensin-converting enzyme 2 (ACE2) is a receptor for human respiratory coronavirus NL63.

Smith MK, Tusell S, Travanty EA, Berkhout B, van der Hoek L, Holmes KV.

Adv Exp Med Biol. 2006;581:285-8. No abstract available.

PMID:
17037544
39.

Human coronavirus 229E can use CD209L (L-SIGN) to enter cells.

Jeffers SA, Hemmila EM, Holmes KV.

Adv Exp Med Biol. 2006;581:265-9. No abstract available.

PMID:
17037540
40.

Bats: important reservoir hosts of emerging viruses.

Calisher CH, Childs JE, Field HE, Holmes KV, Schountz T.

Clin Microbiol Rev. 2006 Jul;19(3):531-45. Review.

41.

Template-based coiled-coil antigens elicit neutralizing antibodies to the SARS-coronavirus.

Tripet B, Kao DJ, Jeffers SA, Holmes KV, Hodges RS.

J Struct Biol. 2006 Aug;155(2):176-94. Epub 2006 Apr 27.

PMID:
16697221
42.

Structural biology. Adaptation of SARS coronavirus to humans.

Holmes KV.

Science. 2005 Sep 16;309(5742):1822-3. No abstract available.

PMID:
16166506
43.

Cells of human aminopeptidase N (CD13) transgenic mice are infected by human coronavirus-229E in vitro, but not in vivo.

Wentworth DE, Tresnan DB, Turner BC, Lerman IR, Bullis B, Hemmila EM, Levis R, Shapiro LH, Holmes KV.

Virology. 2005 May 10;335(2):185-97.

45.

CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus.

Jeffers SA, Tusell SM, Gillim-Ross L, Hemmila EM, Achenbach JE, Babcock GJ, Thomas WD Jr, Thackray LB, Young MD, Mason RJ, Ambrosino DM, Wentworth DE, Demartini JC, Holmes KV.

Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15748-53. Epub 2004 Oct 20.

46.

Ceacam1a-/- mice are completely resistant to infection by murine coronavirus mouse hepatitis virus A59.

Hemmila E, Turbide C, Olson M, Jothy S, Holmes KV, Beauchemin N.

J Virol. 2004 Sep;78(18):10156-65.

48.

Expression of the mouse hepatitis virus receptor by central nervous system microglia.

Ramakrishna C, Bergmann CC, Holmes KV, Stohlman SA.

J Virol. 2004 Jul;78(14):7828-32.

50.

Receptor-dependent coronavirus infection of dendritic cells.

Turner BC, Hemmila EM, Beauchemin N, Holmes KV.

J Virol. 2004 May;78(10):5486-90.

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