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Substituting ground woody plants for cottonseed hulls in kid goat feedlot diets: growth performance and blood serum chemistry.

Glasscock JL, Whitney TR, Navarro JR, Angle SG, Holmes AR, Stewart WC, Scholljegerdes EJ.

J Anim Sci. 2018 Jun 29;96(7):2851-2860. doi: 10.1093/jas/sky159.


Adhesion of Yeast and Bacteria to Oral Surfaces.

Cannon RD, Lyons KM, Chong K, Newsham-West K, Niimi K, Holmes AR.

Methods Mol Biol. 2017;1537:165-190.


Multilocus sequence typing (MLST) analysis of Candida albicans isolates colonizing acrylic dentures before and after denture replacement.

Choo KH, Lee HJ, Knight NJ, Holmes AR, Cannon RD.

Med Mycol. 2017 Aug 1;55(6):673-679. doi: 10.1093/mmy/myw128.


Targeting efflux pumps to overcome antifungal drug resistance.

Holmes AR, Cardno TS, Strouse JJ, Ivnitski-Steele I, Keniya MV, Lackovic K, Monk BC, Sklar LA, Cannon RD.

Future Med Chem. 2016 Aug;8(12):1485-501. doi: 10.4155/fmc-2016-0050. Epub 2016 Jul 27. Review.


Pulmonary Microscopic Polyangiitis Presenting as Acute Respiratory Failure from Diffuse Alveolar Hemorrhage.

Roberts KK, Chamberlin MM, Holmes AR, Henderson JL, Hutton RL, Hannah WN, Morris MJ.

Sarcoidosis Vasc Diffuse Lung Dis. 2016 Jan 18;32(4):372-7.


Secretory component mediates Candida albicans binding to epithelial cells.

van der Wielen PA, Holmes AR, Cannon RD.

Oral Dis. 2016 Jan;22(1):69-74. doi: 10.1111/odi.12397.


Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer.

Candido Dos Reis FJ, Lynn S, Ali HR, Eccles D, Hanby A, Provenzano E, Caldas C, Howat WJ, McDuffus LA, Liu B, Daley F, Coulson P, Vyas RJ, Harris LM, Owens JM, Carton AF, McQuillan JP, Paterson AM, Hirji Z, Christie SK, Holmes AR, Schmidt MK, Garcia-Closas M, Easton DF, Bolla MK, Wang Q, Benitez J, Milne RL, Mannermaa A, Couch F, Devilee P, Tollenaar RA, Seynaeve C, Cox A, Cross SS, Blows FM, Sanders J, de Groot R, Figueroa J, Sherman M, Hooning M, Brenner H, Holleczek B, Stegmaier C, Lintott C, Pharoah PD.

EBioMedicine. 2015 May 9;2(7):681-9. doi: 10.1016/j.ebiom.2015.05.009. eCollection 2015 Jul.


Selective Advantages of a Parasexual Cycle for the Yeast Candida albicans.

Zhang N, Magee BB, Magee PT, Holland BR, Rodrigues E, Holmes AR, Cannon RD, Schmid J.

Genetics. 2015 Aug;200(4):1117-32. doi: 10.1534/genetics.115.177170. Epub 2015 Jun 10.


Learning the ABC of oral fungal drug resistance.

Cannon RD, Holmes AR.

Mol Oral Microbiol. 2015 Dec;30(6):425-37. doi: 10.1111/omi.12109. Epub 2015 Jul 2. Review.


Drug resistance is conferred on the model yeast Saccharomyces cerevisiae by expression of full-length melanoma-associated human ATP-binding cassette transporter ABCB5.

Keniya MV, Holmes AR, Niimi M, Lamping E, Gillet JP, Gottesman MM, Cannon RD.

Mol Pharm. 2014 Oct 6;11(10):3452-62. doi: 10.1021/mp500230b. Epub 2014 Aug 22.


In vitro expression of Candida albicans alcohol dehydrogenase genes involved in acetaldehyde metabolism.

Bakri MM, Rich AM, Cannon RD, Holmes AR.

Mol Oral Microbiol. 2015 Feb;30(1):27-38. doi: 10.1111/omi.12064. Epub 2014 Sep 15.


Detection of Candida albicans ADH1 and ADH2 mRNAs in human archival oral biopsy samples.

Bakri MM, Cannon RD, Holmes AR, Rich AM.

J Oral Pathol Med. 2014 Oct;43(9):704-10. doi: 10.1111/jop.12193. Epub 2014 Jun 14.


Adherence of Candida albicans to silicone is promoted by the human salivary protein SPLUNC2/PSP/BPIFA2.

Holmes AR, Rodrigues E, van der Wielen P, Lyons KM, Haigh BJ, Wheeler TT, Dawes PJ, Cannon RD.

Mol Oral Microbiol. 2014 Apr;29(2):90-8. doi: 10.1111/omi.12048. Epub 2014 Feb 8.


Use of denaturing gradient gel electrophoresis for the identification of mixed oral yeasts in human saliva.

Weerasekera MM, Sissons CH, Wong L, Anderson S, Holmes AR, Cannon RD.

J Med Microbiol. 2013 Feb;62(Pt 2):319-30. doi: 10.1099/jmm.0.050237-0. Epub 2012 Oct 11.


Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a D-octapeptide derivative inhibitor.

Niimi K, Harding DR, Holmes AR, Lamping E, Niimi M, Tyndall JD, Cannon RD, Monk BC.

Mol Microbiol. 2012 Aug;85(4):747-67. doi: 10.1111/j.1365-2958.2012.08140.x. Epub 2012 Jul 13.


A D-octapeptide drug efflux pump inhibitor acts synergistically with azoles in a murine oral candidiasis infection model.

Hayama K, Ishibashi H, Ishijima SA, Niimi K, Tansho S, Ono Y, Monk BC, Holmes AR, Harding DR, Cannon RD, Abe S.

FEMS Microbiol Lett. 2012 Mar;328(2):130-7. doi: 10.1111/j.1574-6968.2011.02490.x. Epub 2012 Jan 16.


The monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump activities which reverses the azole resistance of Candida albicans and Candida glabrata clinical isolates.

Holmes AR, Keniya MV, Ivnitski-Steele I, Monk BC, Lamping E, Sklar LA, Cannon RD.

Antimicrob Agents Chemother. 2012 Mar;56(3):1508-15. doi: 10.1128/AAC.05706-11. Epub 2011 Dec 27.


Chimeras of Candida albicans Cdr1p and Cdr2p reveal features of pleiotropic drug resistance transporter structure and function.

Tanabe K, Lamping E, Nagi M, Okawada A, Holmes AR, Miyazaki Y, Cannon RD, Monk BC, Niimi M.

Mol Microbiol. 2011 Oct;82(2):416-33. doi: 10.1111/j.1365-2958.2011.07820.x. Epub 2011 Sep 19.


N-acetylglucosamine increases symptoms and fungal burden in a murine model of oral candidiasis.

Ishijima SA, Hayama K, Takahashi M, Holmes AR, Cannon RD, Abe S.

Med Mycol. 2012 Apr;50(3):252-8. doi: 10.3109/13693786.2011.598194. Epub 2011 Aug 23.


Adhesion of yeast and bacteria to oral surfaces.

Cannon RD, Lyons KM, Chong K, Holmes AR.

Methods Mol Biol. 2010;666:103-24. doi: 10.1007/978-1-60761-820-1_8.


Fungal PDR transporters: Phylogeny, topology, motifs and function.

Lamping E, Baret PV, Holmes AR, Monk BC, Goffeau A, Cannon RD.

Fungal Genet Biol. 2010 Feb;47(2):127-42. doi: 10.1016/j.fgb.2009.10.007. Epub 2009 Oct 24. Review.


An in-vitro device for the assessment of biofilm mediated voice prosthesis damage: how we do it.

Rodrigues E, Chong K, Holmes AR, Cannon RD, Ruske DR, Dawes PJ.

Clin Otolaryngol. 2009 Oct;34(5):481-4. doi: 10.1111/j.1749-4486.2009.01996.x. No abstract available.


Identification of Nile red as a fluorescent substrate of the Candida albicans ATP-binding cassette transporters Cdr1p and Cdr2p and the major facilitator superfamily transporter Mdr1p.

Ivnitski-Steele I, Holmes AR, Lamping E, Monk BC, Cannon RD, Sklar LA.

Anal Biochem. 2009 Nov 1;394(1):87-91. doi: 10.1016/j.ab.2009.07.001. Epub 2009 Jul 3.


Presbyterians and science in the north of Ireland before 1874.

Holmes AR.

Br J Hist Sci. 2008 Dec;41(151 Pt 4):541-65.


Efflux-mediated antifungal drug resistance.

Cannon RD, Lamping E, Holmes AR, Niimi K, Baret PV, Keniya MV, Tanabe K, Niimi M, Goffeau A, Monk BC.

Clin Microbiol Rev. 2009 Apr;22(2):291-321, Table of Contents. doi: 10.1128/CMR.00051-08. Review.


Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei.

Lamping E, Ranchod A, Nakamura K, Tyndall JD, Niimi K, Holmes AR, Niimi M, Cannon RD.

Antimicrob Agents Chemother. 2009 Feb;53(2):354-69. doi: 10.1128/AAC.01095-08. Epub 2008 Nov 17.


ABC transporter Cdr1p contributes more than Cdr2p does to fluconazole efflux in fluconazole-resistant Candida albicans clinical isolates.

Holmes AR, Lin YH, Niimi K, Lamping E, Keniya M, Niimi M, Tanabe K, Monk BC, Cannon RD.

Antimicrob Agents Chemother. 2008 Nov;52(11):3851-62. doi: 10.1128/AAC.00463-08. Epub 2008 Aug 18.


Direct comparison of the pharmacodynamics of four antifungal drugs in a mouse model of disseminated candidiasis using microbiological assays of serum drug concentrations.

Maki K, Holmes AR, Watabe E, Iguchi Y, Matsumoto S, Ikeda F, Tawara S, Mutoh S.

Microbiol Immunol. 2007;51(11):1053-9.


Candida albicans drug resistance another way to cope with stress.

Cannon RD, Lamping E, Holmes AR, Niimi K, Tanabe K, Niimi M, Monk BC.

Microbiology. 2007 Oct;153(Pt 10):3211-7. Review.


Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae.

Lamping E, Monk BC, Niimi K, Holmes AR, Tsao S, Tanabe K, Niimi M, Uehara Y, Cannon RD.

Eukaryot Cell. 2007 Jul;6(7):1150-65. Epub 2007 May 18.


Production from dairy cows of semi-industrial quantities of milk-protein concentrate (MPC) containing efficacious anti-Candida albicans IgA antibodies.

Hodgkinson AJ, Cannon RD, Holmes AR, Fischer FJ, Willix-Payne DJ.

J Dairy Res. 2007 Aug;74(3):269-75. Epub 2007 Apr 30.


Amino acid residues affecting drug pump function in Candida albicans--C. albicans drug pump function.

Holmes AR, Tsao S, Lamping E, Niimi K, Monk BC, Tanabe K, Niimi M, Cannon RD.

Nihon Ishinkin Gakkai Zasshi. 2006;47(4):275-81. Review.


Candida albicans binds to saliva proteins selectively adsorbed to silicone.

Holmes AR, van der Wielen P, Cannon RD, Ruske D, Dawes P.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Oct;102(4):488-94. Epub 2006 Jun 27.


Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2.

Holmes AR, Tsao S, Ong SW, Lamping E, Niimi K, Monk BC, Niimi M, Kaneko A, Holland BR, Schmid J, Cannon RD.

Mol Microbiol. 2006 Oct;62(1):170-86. Epub 2006 Aug 30.


Overexpression of Candida albicans CDR1, CDR2, or MDR1 does not produce significant changes in echinocandin susceptibility.

Niimi K, Maki K, Ikeda F, Holmes AR, Lamping E, Niimi M, Monk BC, Cannon RD.

Antimicrob Agents Chemother. 2006 Apr;50(4):1148-55.


[ABC transporters of pathogenic fungi: recent advances in functional analyses].

Niimi M, Tanabe K, Wada S, Yamazaki A, Uehara Y, Niimi K, Lamping E, Holmes AR, Monk BC, Cannon RD.

Nihon Ishinkin Gakkai Zasshi. 2005;46(4):249-60. Review. Japanese.


Functional analysis of fungal drug efflux transporters by heterologous expression in Saccharomyces cerevisiae.

Niimi M, Wada S, Tanabe K, Kaneko A, Takano Y, Umeyama T, Hanaoka N, Uehara Y, Lamping E, Niimi K, Tsao S, Holmes AR, Monk BC, Cannon RD.

Jpn J Infect Dis. 2005 Feb;58(1):1-7. Review.


Regulated overexpression of CDR1 in Candida albicans confers multidrug resistance.

Niimi M, Niimi K, Takano Y, Holmes AR, Fischer FJ, Uehara Y, Cannon RD.

J Antimicrob Chemother. 2004 Dec;54(6):999-1006. Epub 2004 Oct 14.


Detection of Candida albicans mRNA in archival histopathology samples by reverse transcription-PCR.

Beggs KT, Holmes AR, Cannon RD, Rich AM.

J Clin Microbiol. 2004 May;42(5):2275-8.


Antifungal drug susceptibilities of commensal Candida isolates.

Holmes AR, Niimi M, Girgis JM, Boyd DH, Cannon RD.

N Z Dent J. 2002 Jun;98(432):36-9.


Saliva promotes Candida albicans adherence to human epithelial cells.

Holmes AR, Bandara BM, Cannon RD.

J Dent Res. 2002 Jan;81(1):28-32.


Functional expression of Candida albicans drug efflux pump Cdr1p in a Saccharomyces cerevisiae strain deficient in membrane transporters.

Nakamura K, Niimi M, Niimi K, Holmes AR, Yates JE, Decottignies A, Monk BC, Goffeau A, Cannon RD.

Antimicrob Agents Chemother. 2001 Dec;45(12):3366-74.


The pavA gene of Streptococcus pneumoniae encodes a fibronectin-binding protein that is essential for virulence.

Holmes AR, McNab R, Millsap KW, Rohde M, Hammerschmidt S, Mawdsley JL, Jenkinson HF.

Mol Microbiol. 2001 Sep;41(6):1395-408.


Transfer and expression of foreign genes in mammalian cells.

Colosimo A, Goncz KK, Holmes AR, Kunzelmann K, Novelli G, Malone RW, Bennett MJ, Gruenert DC.

Biotechniques. 2000 Aug;29(2):314-8, 320-2, 324 passim. Review.


Intracellular compartmentalization of DNA fragments in cultured airway epithelial cells mediated by cationic lipids.

Holmes AR, Dohrman AF, Ellison AR, Goncz KK, Gruenert DC.

Pharm Res. 1999 Jul;16(7):1020-5.


Function and immunogenicity of cell-wall-anchored polypeptide CshA in oral streptococci.

Jenkinson HF, McNab R, Holmes AR, Loach DM, Tannock GW.

Adv Exp Med Biol. 1997;418:703-5. No abstract available.


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