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Items: 1 to 50 of 202


Prolonged ocular exposure leads to retinal lesions in mice.

Bell BA, Bonilha VL, Hagstrom SA, Anand-Apte B, Hollyfield JG, Samuels IS.

Exp Eye Res. 2019 Aug;185:107672. doi: 10.1016/j.exer.2019.05.012. Epub 2019 May 22.


Retinal angiotensin II and angiotensin-(1-7) response to hyperglycemia and an intervention with captopril.

Senanayake PD, Bonilha VL, W Peterson J, Yamada Y, Karnik SS, Daneshgari F, Brosnihan KB, Hollyfield JG.

J Renin Angiotensin Aldosterone Syst. 2018 Jul-Sep;19(3):1470320318789323. doi: 10.1177/1470320318789323.


Correction: DJ-1-Dependent Regulation of Oxidative Stress in the Retinal Pigment Epithelium (RPE).

Shadrach KG, Rayborn ME, Hollyfield JG, Bonilha VL.

PLoS One. 2017 Oct 2;12(10):e0185834. doi: 10.1371/journal.pone.0185834. eCollection 2017.


Absence of DJ-1 causes age-related retinal abnormalities in association with increased oxidative stress.

Bonilha VL, Bell BA, Rayborn ME, Samuels IS, King A, Hollyfield JG, Xie C, Cai H.

Free Radic Biol Med. 2017 Mar;104:226-237. doi: 10.1016/j.freeradbiomed.2017.01.018. Epub 2017 Jan 11.


Corrigendum to "In memoriam" [Exp. Eye Res. 140 (2015) iii-iv].

Belmont C, Hollyfield JG.

Exp Eye Res. 2016 Apr;145:474. doi: 10.1016/j.exer.2016.03.022. Epub 2016 Apr 20. No abstract available.


Light-Regulated Thyroid Hormone Signaling Is Required for Rod Photoreceptor Development in the Mouse Retina.

Sawant O, Horton AM, Shukla M, Rayborn ME, Peachey NS, Hollyfield JG, Rao S.

Invest Ophthalmol Vis Sci. 2015 Dec;56(13):8248-57. doi: 10.1167/iovs.15-17743.


Endre A. Balazs, 1920–2015, In Memoriam

Belmont C, Hollyfield JG.

Exp Eye Res. 2015 Nov;140:iii-iv. doi: 10.1016/j.exer.2015.10.002. No abstract available. Erratum in: Exp Eye Res. 2016 Apr;145:474.


Loss of DJ-1 elicits retinal abnormalities, visual dysfunction, and increased oxidative stress in mice.

Bonilha VL, Bell BA, Rayborn ME, Yang X, Kaul C, Grossman GH, Samuels IS, Hollyfield JG, Xie C, Cai H, Shadrach KG.

Exp Eye Res. 2015 Oct;139:22-36. doi: 10.1016/j.exer.2015.07.014. Epub 2015 Jul 26.


Retinal histopathology in eyes from patients with autosomal dominant retinitis pigmentosa caused by rhodopsin mutations.

Bonilha VL, Rayborn ME, Bell BA, Marino MJ, Beight CD, Pauer GJ, Traboulsi EI, Hollyfield JG, Hagstrom SA.

Graefes Arch Clin Exp Ophthalmol. 2015 Dec;253(12):2161-9. doi: 10.1007/s00417-015-3099-7. Epub 2015 Jul 23.


The BALB/c mouse: Effect of standard vivarium lighting on retinal pathology during aging.

Bell BA, Kaul C, Bonilha VL, Rayborn ME, Shadrach K, Hollyfield JG.

Exp Eye Res. 2015 Jun;135:192-205. doi: 10.1016/j.exer.2015.04.009. Epub 2015 Apr 18.


Histopathology of the Retina from a Three Year-Old Suspected to Have Joubert Syndrome.

Bonilha VL, Rayborn ME, Bell BA, Marino MJ, Traboulsi EI, Hagstrom SA, Hollyfield JG.

Austin J Clin Ophthalmol. 2015;2(4). pii: 1057. Epub 2015 Sep 21.


Histopathological comparison of eyes from patients with autosomal recessive retinitis pigmentosa caused by novel EYS mutations.

Bonilha VL, Rayborn ME, Bell BA, Marino MJ, Pauer GJ, Beight CD, Chiang J, Traboulsi EI, Hollyfield JG, Hagstrom SA.

Graefes Arch Clin Exp Ophthalmol. 2015 Feb;253(2):295-305. doi: 10.1007/s00417-014-2868-z. Epub 2014 Dec 11.


Retinal vasculature of adult zebrafish: in vivo imaging using confocal scanning laser ophthalmoscopy.

Bell BA, Xie J, Yuan A, Kaul C, Hollyfield JG, Anand-Apte B.

Exp Eye Res. 2014 Dec;129:107-18. doi: 10.1016/j.exer.2014.10.018. Epub 2014 Oct 24.


Retinal Histopathology in Eyes from a Patient with Stargardt disease caused by Compound Heterozygous ABCA4 Mutations.

Bonilha VL, Rayborn ME, Bell BA, Marino MJ, Fishman GA, Hollyfield JG.

Ophthalmic Genet. 2016 Jun;37(2):150-60. doi: 10.3109/13816810.2014.958861. Epub 2014 Sep 29.


A protective eye shield for prevention of media opacities during small animal ocular imaging.

Bell BA, Kaul C, Hollyfield JG.

Exp Eye Res. 2014 Oct;127:280-7. doi: 10.1016/j.exer.2014.01.001. No abstract available.


Retinal regeneration following OCT-guided laser injury in zebrafish.

DiCicco RM, Bell BA, Kaul C, Hollyfield JG, Anand-Apte B, Perkins BD, Tao YK, Yuan A.

Invest Ophthalmol Vis Sci. 2014 Sep 9;55(10):6281-8. doi: 10.1167/iovs.14-14724.


CEP biomarkers as potential tools for monitoring therapeutics.

Renganathan K, Gu J, Rayborn ME, Crabb JS, Salomon RG, Collier RJ, Kapin MA, Romano C, Hollyfield JG, Crabb JW.

PLoS One. 2013 Oct 1;8(10):e76325. doi: 10.1371/journal.pone.0076325. eCollection 2013.


On the use of immortalized ocular cell lines in vision research: the unfortunate story of RGC-5.

Clark A, Tamm ER, Al-Ubaidi MR, Hollyfield JG.

Exp Eye Res. 2013 Nov;116:433. doi: 10.1016/j.exer.2013.08.002. Epub 2013 Sep 7. No abstract available.


Mutations in IMPG1 cause vitelliform macular dystrophies.

Manes G, Meunier I, Avila-Fernández A, Banfi S, Le Meur G, Zanlonghi X, Corton M, Simonelli F, Brabet P, Labesse G, Audo I, Mohand-Said S, Zeitz C, Sahel JA, Weber M, Dollfus H, Dhaenens CM, Allorge D, De Baere E, Koenekoop RK, Kohl S, Cremers FP, Hollyfield JG, Sénéchal A, Hebrard M, Bocquet B, Ayuso García C, Hamel CP.

Am J Hum Genet. 2013 Sep 5;93(3):571-8. doi: 10.1016/j.ajhg.2013.07.018. Epub 2013 Aug 29.


DJ-1-dependent regulation of oxidative stress in the retinal pigment epithelium (RPE).

Shadrach KG, Rayborn ME, Hollyfield JG, Bonilha VL.

PLoS One. 2013 Jul 2;8(7):e67983. doi: 10.1371/journal.pone.0067983. Print 2013. Erratum in: PLoS One. 2014;9(7):104292. PLoS One. 2017 Oct 2;12 (10 ):e0185834.


Retinal deimination and PAD2 levels in retinas from donors with age-related macular degeneration (AMD).

Bonilha VL, Shadrach KG, Rayborn ME, Li Y, Pauer GJ, Hagstrom SA, Bhattacharya SK, Hollyfield JG.

Exp Eye Res. 2013 Jun;111:71-8. doi: 10.1016/j.exer.2013.03.017. Epub 2013 Apr 3.


Infiltration of proinflammatory m1 macrophages into the outer retina precedes damage in a mouse model of age-related macular degeneration.

Cruz-Guilloty F, Saeed AM, Echegaray JJ, Duffort S, Ballmick A, Tan Y, Betancourt M, Viteri E, Ramkhellawan GC, Ewald E, Feuer W, Huang D, Wen R, Hong L, Wang H, Laird JM, Sene A, Apte RS, Salomon RG, Hollyfield JG, Perez VL.

Int J Inflam. 2013;2013:503725. doi: 10.1155/2013/503725. Epub 2013 Mar 7.


Activation of the alternative complement pathway in vitreous is controlled by genetics in age-related macular degeneration.

Loyet KM, Deforge LE, Katschke KJ Jr, Diehl L, Graham RR, Pao L, Sturgeon L, Lewin-Koh SC, Hollyfield JG, van Lookeren Campagne M.

Invest Ophthalmol Vis Sci. 2012 Sep 25;53(10):6628-37.


Age-related changes in the retinal pigment epithelium (RPE).

Gu X, Neric NJ, Crabb JS, Crabb JW, Bhattacharya SK, Rayborn ME, Hollyfield JG, Bonilha VL.

PLoS One. 2012;7(6):e38673. doi: 10.1371/journal.pone.0038673. Epub 2012 Jun 11.


NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components.

Doyle SL, Campbell M, Ozaki E, Salomon RG, Mori A, Kenna PF, Farrar GJ, Kiang AS, Humphries MM, Lavelle EC, O'Neill LA, Hollyfield JG, Humphries P.

Nat Med. 2012 May;18(5):791-8. doi: 10.1038/nm.2717.


Imaging human postmortem eyes with SLO and OCT.

Bagheri N, Bell BA, Bonilha VL, Hollyfield JG.

Adv Exp Med Biol. 2012;723:479-88. doi: 10.1007/978-1-4614-0631-0_60. No abstract available.


Baseline imaging reveals preexisting retinal abnormalities in mice.

Bell BA, Kaul C, Rayborn ME, Hollyfield JG.

Adv Exp Med Biol. 2012;723:459-69. doi: 10.1007/978-1-4614-0631-0_58. No abstract available.


Manuscript fabrication, image manipulation and plagiarism.

Hollyfield JG.

Exp Eye Res. 2012 Jan;94(1):1-2. doi: 10.1016/j.exer.2011.10.009. Epub 2011 Oct 21. No abstract available.


ADAMTSL4, a secreted glycoprotein widely distributed in the eye, binds fibrillin-1 microfibrils and accelerates microfibril biogenesis.

Gabriel LA, Wang LW, Bader H, Ho JC, Majors AK, Hollyfield JG, Traboulsi EI, Apte SS.

Invest Ophthalmol Vis Sci. 2012 Jan 31;53(1):461-9. doi: 10.1167/iovs.10-5955.


Histopathology and functional correlations in a patient with a mutation in RPE65, the gene for retinol isomerase.

Bonilha VL, Rayborn ME, Li Y, Grossman GH, Berson EL, Hollyfield JG.

Invest Ophthalmol Vis Sci. 2011 Oct 28;52(11):8381-92. doi: 10.1167/iovs.11-7973.


Discovery of carboxyethylpyrroles (CEPs): critical insights into AMD, autism, cancer, and wound healing from basic research on the chemistry of oxidized phospholipids.

Salomon RG, Hong L, Hollyfield JG.

Chem Res Toxicol. 2011 Nov 21;24(11):1803-16. doi: 10.1021/tx200206v. Epub 2011 Oct 3. Review.


Light-evoked responses of the retinal pigment epithelium: changes accompanying photoreceptor loss in the mouse.

Samuels IS, Sturgill GM, Grossman GH, Rayborn ME, Hollyfield JG, Peachey NS.

J Neurophysiol. 2010 Jul;104(1):391-402. doi: 10.1152/jn.00088.2010. Epub 2010 May 19.


A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration.

Hollyfield JG, Perez VL, Salomon RG.

Mol Neurobiol. 2010 Jun;41(2-3):290-8. doi: 10.1007/s12035-010-8110-z. Epub 2010 Mar 12.


Age-related macular degeneration: the molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease: the Proctor lecture.

Hollyfield JG.

Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1275-81. doi: 10.1167/iovs.09-4478. No abstract available.


Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes.

Yuan X, Gu X, Crabb JS, Yue X, Shadrach K, Hollyfield JG, Crabb JW.

Mol Cell Proteomics. 2010 Jun;9(6):1031-46. doi: 10.1074/mcp.M900523-MCP200. Epub 2010 Feb 22.


Retinal pathology of a patient with Goldmann-Favre syndrome.

Bonilha VL, Fishman GA, Rayborn ME, Hollyfield JG.

Ophthalmic Genet. 2009 Dec;30(4):172-80. doi: 10.3109/13816810903176765.


Pigment epithelium-derived factor binds to hyaluronan. Mapping of a hyaluronan binding site.

Becerra SP, Perez-Mediavilla LA, Weldon JE, Locatelli-Hoops S, Senanayake P, Notari L, Notario V, Hollyfield JG.

J Biol Chem. 2008 Nov 28;283(48):33310-20. doi: 10.1074/jbc.M801287200. Epub 2008 Sep 19.


Choroideremia: analysis of the retina from a female symptomatic carrier.

Bonilha VL, Trzupek KM, Li Y, Francis PJ, Hollyfield JG, Rayborn ME, Smaoui N, Weleber RG.

Ophthalmic Genet. 2008 Sep;29(3):99-110. doi: 10.1080/13816810802206499.


Amantadine-associated corneal edema potentially irreversible even after cessation of the medication.

Jeng BH, Galor A, Lee MS, Meisler DM, Hollyfield JG, Schoenfield L, McMahon JT, Langston RH.

Ophthalmology. 2008 Sep;115(9):1540-4. doi: 10.1016/j.ophtha.2008.03.011. Epub 2008 May 23.


Retinal pigment epithelium lipofuscin proteomics.

Ng KP, Gugiu B, Renganathan K, Davies MW, Gu X, Crabb JS, Kim SR, Rózanowska MB, Bonilha VL, Rayborn ME, Salomon RG, Sparrow JR, Boulton ME, Hollyfield JG, Crabb JW.

Mol Cell Proteomics. 2008 Jul;7(7):1397-405. doi: 10.1074/mcp.M700525-MCP200. Epub 2008 Apr 24.


In Memoriam: Ruben Adler (November 10, 1940-December 31, 2007).

Hollyfield JG.

Exp Eye Res. 2008 Feb;86(2):165-7. No abstract available.


Age-related reduction in retinal deimination levels in the F344BN rat.

Bhattacharya SK, Sinicrope B, Rayborn ME, Hollyfield JG, Bonilha VL.

Aging Cell. 2008 Jun;7(3):441-4. doi: 10.1111/j.1474-9726.2008.00376.x. Epub 2008 Jan 31.


Oxidative damage-induced inflammation initiates age-related macular degeneration.

Hollyfield JG, Bonilha VL, Rayborn ME, Yang X, Shadrach KG, Lu L, Ufret RL, Salomon RG, Perez VL.

Nat Med. 2008 Feb;14(2):194-8. doi: 10.1038/nm1709. Epub 2008 Jan 27.


Semenogelins in the human retina: Differences in distribution and content between AMD and normal donor tissues.

Bonilha VL, Rayborn ME, Shadrach KG, Li Y, Lundwall A, Malm J, Hollyfield JG.

Exp Eye Res. 2008 Jan;86(1):150-6. Epub 2007 Oct 25.


Angiotensin II and its receptor subtypes in the human retina.

Senanayake Pd, Drazba J, Shadrach K, Milsted A, Rungger-Brandle E, Nishiyama K, Miura S, Karnik S, Sears JE, Hollyfield JG.

Invest Ophthalmol Vis Sci. 2007 Jul;48(7):3301-11.


Interaction between the photoreceptor-specific tubby-like protein 1 and the neuronal-specific GTPase dynamin-1.

Xi Q, Pauer GJ, Ball SL, Rayborn M, Hollyfield JG, Peachey NS, Crabb JW, Hagstrom SA.

Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2837-44.


The retinal pigment epithelium apical microvilli and retinal function.

Bonilha VL, Rayborn ME, Bhattacharya SK, Gu X, Crabb JS, Crabb JW, Hollyfield JG.

Adv Exp Med Biol. 2006;572:519-24. Review. No abstract available.


Annexins in Bruch's membrane and drusen.

Rayborn ME, Sakaguchi H, Shadrach KG, Crabb JW, Hollyfield JG.

Adv Exp Med Biol. 2006;572:75-8. No abstract available.


Mutation screen of the cone-specific gene, CLUL1, in 376 patients with age-related macular degeneration.

Sturgill GM, Pauer GJ, Bala E, Simpson E, Yaniglos SS, Crabb JW, Hollyfield JG, Lewis H, Peachey NS, Hagstrom SA.

Ophthalmic Genet. 2006 Dec;27(4):151-5.


Clathrin and adaptin accumulation in drusen, Bruch's membrane and choroid in AMD and non-AMD donor eyes.

Bando H, Shadrach KG, Rayborn ME, Crabb JW, Hollyfield JG.

Exp Eye Res. 2007 Jan;84(1):135-42. Epub 2006 Nov 13.


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