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Slow Down: Behavioural and Physiological Effects of Reducing Eating Rate.

Hawton K, Ferriday D, Rogers P, Toner P, Brooks J, Holly J, Biernacka K, Hamilton-Shield J, Hinton E.

Nutrients. 2018 Dec 27;11(1). pii: E50. doi: 10.3390/nu11010050.


Using neuroimaging to investigate the impact of Mandolean® training in young people with obesity: a pilot randomised controlled trial.

Hinton EC, Birch LA, Barton J, Holly JMP, Biernacka KM, Leary SD, Wilson A, Byrom OS, Hamilton-Shield JP.

BMC Pediatr. 2018 Nov 22;18(1):366. doi: 10.1186/s12887-018-1342-1.


Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines.

Koobotse M, Holly J, Perks C.

Oncotarget. 2018 Sep 11;9(71):33562-33576. doi: 10.18632/oncotarget.26093. eCollection 2018 Sep 11.


ProDiet: A Phase II Randomized Placebo-controlled Trial of Green Tea Catechins and Lycopene in Men at Increased Risk of Prostate Cancer.

Lane JA, Er V, Avery KNL, Horwood J, Cantwell M, Caro GP, Crozier A, Smith GD, Donovan JL, Down L, Hamdy FC, Gillatt D, Holly J, Macefield R, Moody H, Neal DE, Walsh E, Martin RM, Metcalfe C.

Cancer Prev Res (Phila). 2018 Nov;11(11):687-696. doi: 10.1158/1940-6207.CAPR-18-0147. Epub 2018 Oct 11.


Circulating Growth and Sex Hormone Levels and Breast Tissue Composition in Young Nulliparous Women.

Denholm R, De Stavola BL, Hipwell JH, Doran SJ, Holly JMP, Folkerd E, Dowsett M, Leach MO, Hawkes DJ, Dos-Santos-Silva I.

Cancer Epidemiol Biomarkers Prev. 2018 Dec;27(12):1500-1508. doi: 10.1158/1055-9965.EPI-18-0036. Epub 2018 Sep 18.


Avian influenza A virus adaptation to the equine host and identification of host-specific markers.

Mucha V, Hollý J, Varečková E, Kostolanský F.

Acta Virol. 2018;62(3):266-276. doi: 10.4149/av_2018_220.


Reassessing the Association between Circulating Vitamin D and IGFBP-3: Observational and Mendelian Randomization Estimates from Independent Sources.

Tan VY, Biernacka KM, Dudding T, Bonilla C, Gilbert R, Kaplan RC, Qibin Q, Teumer A, Martin RM, Perks CM, Timpson NJ, Holly JMP; PRACTICAL consortium.

Cancer Epidemiol Biomarkers Prev. 2018 Dec;27(12):1462-1471. doi: 10.1158/1055-9965.EPI-18-0113. Epub 2018 Aug 2.


Insulin-like growth factor-II in adipocyte regulation: depot-specific actions suggest a potential role limiting excess visceral adiposity.

Alfares MN, Perks CM, Hamilton-Shield JP, Holly JMP.

Am J Physiol Endocrinol Metab. 2018 Dec 1;315(6):E1098-E1107. doi: 10.1152/ajpendo.00409.2017. Epub 2018 Jul 24.


Mechanism-specific rehabilitation management of complex regional pain syndrome: Proposed recommendations from evidence synthesis.

Packham T, Holly J.

J Hand Ther. 2018 Apr - Jun;31(2):238-249. doi: 10.1016/j.jht.2018.01.007. Epub 2018 Feb 13.


Inhibition of FASN and ERα signalling during hyperglycaemia-induced matrix-specific EMT promotes breast cancer cell invasion via a caveolin-1-dependent mechanism.

Zielinska HA, Holly JMP, Bahl A, Perks CM.

Cancer Lett. 2018 Apr 10;419:187-202. doi: 10.1016/j.canlet.2018.01.028. Epub 2018 Jan 11.


Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 men.

Watts EL, Appleby PN, Albanes D, Black A, Chan JM, Chen C, Cirillo PM, Cohn BA, Cook MB, Donovan JL, Ferrucci L, Garland CF, Giles GG, Goodman PJ, Habel LA, Haiman CA, Holly JMP, Hoover RN, Kaaks R, Knekt P, Kolonel LN, Kubo T, Le Marchand L, Luostarinen T, MacInnis RJ, Mäenpää HO, Männistö S, Metter EJ, Milne RL, Nomura AMY, Oliver SE, Parsons JK, Peeters PH, Platz EA, Riboli E, Ricceri F, Rinaldi S, Rissanen H, Sawada N, Schaefer CA, Schenk JM, Stanczyk FZ, Stampfer M, Stattin P, Stenman UH, Tjønneland A, Trichopoulou A, Thompson IM, Tsugane S, Vatten L, Whittemore AS, Ziegler RG, Allen NE, Key TJ, Travis RC.

PLoS One. 2017 Dec 27;12(12):e0187741. doi: 10.1371/journal.pone.0187741. eCollection 2017.


Hyperglycemia Promotes TMPRSS2-ERG Gene Fusion in Prostate Cancer Cells via Upregulating Insulin-Like Growth Factor-Binding Protein-2.

Holly JMP, Broadhurst J, Mansor R, Bahl A, Perks CM.

Front Endocrinol (Lausanne). 2017 Nov 6;8:305. doi: 10.3389/fendo.2017.00305. eCollection 2017.


Hypoxia negates hyperglycaemia-induced chemo-resistance in breast cancer cells: the role of insulin-like growth factor binding protein 2.

Al Qahtani A, Holly J, Perks C.

Oncotarget. 2017 Aug 16;8(43):74635-74648. doi: 10.18632/oncotarget.20287. eCollection 2017 Sep 26.


Developing the WCRF International/University of Bristol Methodology for Identifying and Carrying Out Systematic Reviews of Mechanisms of Exposure-Cancer Associations.

Lewis SJ, Gardner M, Higgins J, Holly JMP, Gaunt TR, Perks CM, Turner SD, Rinaldi S, Thomas S, Harrison S, Lennon RJ, Tan V, Borwick C, Emmett P, Jeffreys M, Northstone K, Mitrou G, Wiseman M, Thompson R, Martin RM.

Cancer Epidemiol Biomarkers Prev. 2017 Nov;26(11):1667-1675. doi: 10.1158/1055-9965.EPI-17-0232. Epub 2017 Oct 4.


Post-diagnosis serum insulin-like growth factors in relation to dietary and lifestyle changes in the Prostate testing for cancer and Treatment (ProtecT) trial.

Er V, Biernacka K, Simpkin AJ, Martin RM, Jeffreys M, Emmett P, Gilbert R, Avery KNL, Walsh E, Davis M, Donovan JL, Neal DE, Hamdy FC, Holly JMP, Lane JA.

Cancer Causes Control. 2017 Aug;28(8):877-888. doi: 10.1007/s10552-017-0910-2. Epub 2017 Jun 23.


Comparison of infectious influenza A virus quantification methods employing immuno-staining.

Hollý J, Fogelová M, Jakubcová L, Tomčíková K, Vozárová M, Varečková E, Kostolanský F.

J Virol Methods. 2017 Sep;247:107-113. doi: 10.1016/j.jviromet.2017.06.004. Epub 2017 Jun 10.


Does milk intake promote prostate cancer initiation or progression via effects on insulin-like growth factors (IGFs)? A systematic review and meta-analysis.

Harrison S, Lennon R, Holly J, Higgins JPT, Gardner M, Perks C, Gaunt T, Tan V, Borwick C, Emmet P, Jeffreys M, Northstone K, Rinaldi S, Thomas S, Turner SD, Pease A, Vilenchick V, Martin RM, Lewis SJ.

Cancer Causes Control. 2017 Jun;28(6):497-528. doi: 10.1007/s10552-017-0883-1. Epub 2017 Mar 30. Review.


Recommendations for a first Core Outcome Measurement set for complex regional PAin syndrome Clinical sTudies (COMPACT).

Grieve S, Perez RSGM, Birklein F, Brunner F, Bruehl S, Harden RN, Packham T, Gobeil F, Haigh R, Holly J, Terkelsen A, Davies L, Lewis J, Thomassen I, Connett R, Worth T, Vatine JJ, McCabe CS.

Pain. 2017 Jun;158(6):1083-1090. doi: 10.1097/j.pain.0000000000000866.


Complex regional pain syndrome: Measurement matters: Re: Galve-Villa M, Rittig-Rasmussen B, Mikkelsen LMS, Poulsen AG. Complex Regional Pain Syndrome. Manual Therapy 2016;26:e2-3.

Packham T, Holly J.

Man Ther. 2016 Dec;26:e1. doi: 10.1016/j.math.2016.07.012. Epub 2016 Aug 2. No abstract available.


Hyperglycaemia-induced resistance to Docetaxel is negated by metformin: a role for IGFBP-2.

Biernacka KM, Persad RA, Bahl A, Gillatt D, Holly JM, Perks CM.

Endocr Relat Cancer. 2017 Jan;24(1):17-30. Epub 2016 Oct 17.


Insulin Receptor Isoform Variations in Prostate Cancer Cells.

Perks CM, Zielinska HA, Wang J, Jarrett C, Frankow A, Ladomery MR, Bahl A, Rhodes A, Oxley J, Holly JM.

Front Endocrinol (Lausanne). 2016 Sep 28;7:132. eCollection 2016.


The role of fusion activity of influenza A viruses in their biological properties.

Jakubcová L, Hollý J, Varečková E.

Acta Virol. 2016 Jun;60(2):121-35. Review.


Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels.

Bonilla C, Lewis SJ, Rowlands MA, Gaunt TR, Davey Smith G, Gunnell D, Palmer T, Donovan JL, Hamdy FC, Neal DE, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Grönberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H; PRACTICAL consortium, Lathrop M, Martin RM, Holly JM.

Int J Cancer. 2016 Oct 1;139(7):1520-33. doi: 10.1002/ijc.30206. Epub 2016 Jun 23.


Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations.

Christiansen JS, Backeljauw PF, Bidlingmaier M, Biller BM, Boguszewski MC, Casanueva FF, Chanson P, Chatelain P, Choong CS, Clemmons DR, Cohen LE, Cohen P, Frystyk J, Grimberg A, Hasegawa Y, Haymond MW, Ho K, Hoffman AR, Holly JM, Horikawa R, Höybye C, Jorgensen JO, Johannsson G, Juul A, Katznelson L, Kopchick JJ, Lee KO, Lee KW, Luo X, Melmed S, Miller BS, Misra M, Popovic V, Rosenfeld RG, Ross J, Ross RJ, Saenger P, Strasburger CJ, Thorner MO, Werner H, Yuen K.

Eur J Endocrinol. 2016 Jun;174(6):C1-8. doi: 10.1530/EJE-16-0111. Epub 2016 Mar 23.


Blood lipids and prostate cancer: a Mendelian randomization analysis.

Bull CJ, Bonilla C, Holly JM, Perks CM, Davies N, Haycock P, Yu OH, Richards JB, Eeles R, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, MacInnis RJ, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Micheal A, Pandha H, Smith GD, Lewis SJ, Martin RM; PRACTICAL consortium.

Cancer Med. 2016 Jun;5(6):1125-36. doi: 10.1002/cam4.695. Epub 2016 Mar 19.


Prostate cancer - evidence of exercise and nutrition trial (PrEvENT): study protocol for a randomised controlled feasibility trial.

Hackshaw-McGeagh L, Lane JA, Persad R, Gillatt D, Holly JM, Koupparis A, Rowe E, Johnston L, Cloete J, Shiridzinomwa C, Abrams P, Penfold CM, Bahl A, Oxley J, Perks CM, Martin R.

Trials. 2016 Mar 7;17(1):123. doi: 10.1186/s13063-016-1248-x.


A Meta-analysis of Individual Participant Data Reveals an Association between Circulating Levels of IGF-I and Prostate Cancer Risk.

Travis RC, Appleby PN, Martin RM, Holly JMP, Albanes D, Black A, Bueno-de-Mesquita HBA, Chan JM, Chen C, Chirlaque MD, Cook MB, Deschasaux M, Donovan JL, Ferrucci L, Galan P, Giles GG, Giovannucci EL, Gunter MJ, Habel LA, Hamdy FC, Helzlsouer KJ, Hercberg S, Hoover RN, Janssen JAMJL, Kaaks R, Kubo T, Le Marchand L, Metter EJ, Mikami K, Morris JK, Neal DE, Neuhouser ML, Ozasa K, Palli D, Platz EA, Pollak M, Price AJ, Roobol MJ, Schaefer C, Schenk JM, Severi G, Stampfer MJ, Stattin P, Tamakoshi A, Tangen CM, Touvier M, Wald NJ, Weiss NS, Ziegler RG, Key TJ, Allen NE.

Cancer Res. 2016 Apr 15;76(8):2288-2300. doi: 10.1158/0008-5472.CAN-15-1551. Epub 2016 Feb 26.


Expression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian cancer.

Schmid G, Notaro S, Reimer D, Abdel-Azim S, Duggan-Peer M, Holly J, Fiegl H, Rössler J, Wiedemair A, Concin N, Altevogt P, Marth C, Zeimet AG.

BMC Cancer. 2016 Feb 15;16:102. doi: 10.1186/s12885-016-2135-2.


γ-Glutamyltransferase and Breast Cancer Risk Beyond Alcohol Consumption and Other Life Style Factors - A Pooled Cohort Analysis.

Preyer O, Johansen D, Holly J, Stocks T, Pompella A, Nagel G, Concin H, Ulmer H, Concin N.

PLoS One. 2016 Feb 10;11(2):e0149122. doi: 10.1371/journal.pone.0149122. eCollection 2016.


Hyperglycaemia-induced chemoresistance in breast cancer cells: role of the estrogen receptor.

Zeng L, Zielinska HA, Arshad A, Shield JP, Bahl A, Holly JM, Perks CM.

Endocr Relat Cancer. 2016 Feb;23(2):125-34. doi: 10.1530/ERC-15-0507. Epub 2015 Dec 8.


Socioeconomic conditions across life related to multiple measures of the endocrine system in older adults: Longitudinal findings from a British birth cohort study.

Bann D, Hardy R, Cooper R, Lashen H, Keevil B, Wu FC, Holly JM, Ong KK, Ben-Shlomo Y, Kuh D.

Soc Sci Med. 2015 Dec;147:190-9. doi: 10.1016/j.socscimed.2015.11.001. Epub 2015 Nov 6.


Image of the Month. Celiac disease presenting with acquired acrodermatitis enteropathica.

Mir F, Bechtold ML, Holly JS, Hammad H.

Am J Gastroenterol. 2015 Oct;110(10):1396. doi: 10.1038/ajg.2015.99. No abstract available.


The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium.

Davies NM, Gaunt TR, Lewis SJ, Holly J, Donovan JL, Hamdy FC, Kemp JP, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H; PRACTICAL consortium, Lathrop M, Smith GD, Martin RM.

Cancer Causes Control. 2015 Nov;26(11):1603-16. doi: 10.1007/s10552-015-0654-9. Epub 2015 Sep 19.


Current Understanding of Circulating Tumor Cells - Potential Value in Malignancies of the Central Nervous System.

Adamczyk LA, Williams H, Frankow A, Ellis HP, Haynes HR, Perks C, Holly JM, Kurian KM.

Front Neurol. 2015 Aug 10;6:174. doi: 10.3389/fneur.2015.00174. eCollection 2015. Review.


Pseudomelanosis Duodeni.

Sathyamurthy A, Chela H, Arif Z, Holly J, Arif M.

ACG Case Rep J. 2015 Jan 16;2(2):72-3. doi: 10.14309/crj.2015.6. eCollection 2015 Jan. No abstract available.


Epigenetic regulation of insulin-like growth factor binding protein-3 (IGFBP-3) in cancer.

Perks CM, Holly JM.

J Cell Commun Signal. 2015 Jun;9(2):159-66. doi: 10.1007/s12079-015-0294-6. Epub 2015 Apr 29.


The ubiquitination of the influenza A virus PB1-F2 protein is crucial for its biological function.

Košík I, Práznovská M, Košíková M, Bobišová Z, Hollý J, Varečková E, Kostolanský F, Russ G.

PLoS One. 2015 Apr 13;10(4):e0118477. doi: 10.1371/journal.pone.0118477. eCollection 2015.


Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer.

Rosendahl AH, Perks CM, Zeng L, Markkula A, Simonsson M, Rose C, Ingvar C, Holly JM, Jernström H.

Clin Cancer Res. 2015 Apr 15;21(8):1877-87. doi: 10.1158/1078-0432.CCR-14-1748. Epub 2015 Feb 17.


IGFBP-2/PTEN: A critical interaction for tumours and for general physiology?

Zeng L, Perks CM, Holly JM.

Growth Horm IGF Res. 2015 Jun;25(3):103-7. doi: 10.1016/j.ghir.2015.01.003. Epub 2015 Feb 8. Review.


Changes in insulin-like growth factor-I and -II associated with fat but not lean mass in early old age.

Bann D, Holly JM, Lashen H, Hardy R, Adams J, Kuh D, Ong KK, Ben-Shlomo Y.

Obesity (Silver Spring). 2015 Mar;23(3):692-8. doi: 10.1002/oby.21002. Epub 2015 Feb 3.


Epithelial-to-mesenchymal transition in breast cancer: a role for insulin-like growth factor I and insulin-like growth factor-binding protein 3?

Zielinska HA, Bahl A, Holly JM, Perks CM.

Breast Cancer (Dove Med Press). 2015 Jan 19;7:9-19. doi: 10.2147/BCTT.S43932. eCollection 2015. Review.


At 64 years, Peutz-Jeghers syndrome is still in the differential!

Hammad HT, Frazier SR, Holly JS, Esmadi M.

Am J Gastroenterol. 2014 Nov;109(11):1835-7. doi: 10.1038/ajg.2013.433. No abstract available.


Ipilimumab-induced colitis: a rare but serious side effect.

Hinds AM, Ahmad DS, Muenster JE, Berg ZM, Lopez KT, Holly JS, Matteson-Kome ML, Bechtold ML.

Endoscopy. 2014;46 Suppl 1 UCTN:E308-9. doi: 10.1055/s-0034-1377209. Epub 2014 Jul 24. No abstract available.


Role of IGF-I, IGF-II and IGFBP-3 in lung function of males: the Caerphilly Prospective Study.

Green CJ, Holly JM, Bolton CE, Bayer A, Ebrahim S, Gallacher J, Ben-Shlomo Y.

Int J Mol Epidemiol Genet. 2014 May 29;5(2):112-9. eCollection 2014.


Effects of physiological levels of the green tea extract epigallocatechin-3-gallate on breast cancer cells.

Zeng L, Holly JM, Perks CM.

Front Endocrinol (Lausanne). 2014 May 7;5:61. doi: 10.3389/fendo.2014.00061. eCollection 2014.


The role of IGF-I, IGF-II, and IGFBP-3 in male cognitive aging and dementia risk: the Caerphilly Prospective Study.

Green CJ, Holly JM, Bayer A, Fish M, Ebrahim S, Gallacher J, Ben-Shlomo Y.

J Alzheimers Dis. 2014;41(3):867-75. doi: 10.3233/JAD-132183.


Mucinous carcinoma of the eyelid with colonic mass: a rare partnership.

Hinds AM, Ahmad D, Lopez KT, Holly JS, Matteson-Kome ML, Bechtold ML.

Endoscopy. 2014;46 Suppl 1 UCTN:E107-8. doi: 10.1055/s-0033-1359239. Epub 2014 Mar 27. No abstract available.


Bile duct adenoma with oncocytic features.

Johannesen EJ, Wu Z, Holly JS.

Case Rep Pathol. 2014;2014:282010. doi: 10.1155/2014/282010. Epub 2014 Jan 28.


Loss of PTEN expression is associated with IGFBP2 expression, younger age, and late stage in triple-negative breast cancer.

Dean SJ, Perks CM, Holly JM, Bhoo-Pathy N, Looi LM, Mohammed NA, Mun KS, Teo SH, Koobotse MO, Yip CH, Rhodes A.

Am J Clin Pathol. 2014 Mar;141(3):323-33. doi: 10.1309/AJCPR11DEAYPTUSL.


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