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Items: 1 to 50 of 235

1.

A randomised feasibility trial comparing needle fasciotomy with limited fasciectomy treatment for Dupuytren's contractures.

Davis TRC, Tan W, Harrison EF, Hollingworth W, Karantana A, Mills N, Hepburn T, Sprange K, Duley L, Blazeby JM, Bainbridge CG, Murali SR, Montgomery AA; HAND-1 Study group.

Pilot Feasibility Stud. 2020 Jan 30;6:7. doi: 10.1186/s40814-019-0546-y. eCollection 2020.

2.

Mendelian Randomization analysis of the causal effect of adiposity on hospital costs.

Dixon P, Hollingworth W, Harrison S, Davies NM, Davey Smith G.

J Health Econ. 2020 Jan 25;70:102300. doi: 10.1016/j.jhealeco.2020.102300. [Epub ahead of print]

3.

The use of micro-costing in economic analyses of surgical interventions: a systematic review.

Potter S, Davies C, Davies G, Rice C, Hollingworth W.

Health Econ Rev. 2020 Jan 29;10(1):3. doi: 10.1186/s13561-020-0260-8. Review.

4.

Comparative efficacy and safety of warfarin care bundles and novel oral anticoagulants in patients with atrial fibrillation: a systematic review and network meta-analysis.

Ng SS, Lai NM, Nathisuwan S, Jahan NK, Dilokthornsakul P, Kongpakwattana K, Hollingworth W, Chaiyakunapruk N.

Sci Rep. 2020 Jan 20;10(1):662. doi: 10.1038/s41598-019-57370-2.

5.

Results of the feasibility phase of the managed activity graded exercise in teenagers and pre-adolescents (MAGENTA) randomised controlled trial of treatments for chronic fatigue syndrome/myalgic encephalomyelitis.

Brigden A, Beasant L, Gaunt D, Hollingworth W, Mills N, Solomon-Moore E, Jago R, Metcalfe C, Garfield K, Wray C, Trist A, Vilenchik V, Grayson C, Crawley E.

Pilot Feasibility Stud. 2019 Dec 19;5:151. doi: 10.1186/s40814-019-0525-3. eCollection 2019.

6.

Antidepressant treatment with sertraline for adults with depressive symptoms in primary care: the PANDA research programme including RCT.

Duffy L, Lewis G, Ades A, Araya R, Bone J, Brabyn S, Button K, Churchill R, Croudace T, Derrick C, Dixon P, Dowrick C, Fawsitt C, Fusco L, Gilbody S, Harmer C, Hobbs C, Hollingworth W, Jones V, Kendrick T, Kessler D, Khan N, Kounali D, Lanham P, Malpass A, Munafo M, Pervin J, Peters T, Riozzie D, Robinson J, Salaminios G, Sharp D, Thom H, Thomas L, Welton N, Wiles N, Woodhouse R, Lewis G.

Southampton (UK): NIHR Journals Library; 2019 Dec.

7.

Investigating the effectiveness and cost-effectiveness of FITNET-NHS (Fatigue In Teenagers on the interNET in the NHS) compared to activity management to treat paediatric chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME): amendment to the published protocol.

Anderson E, Gaunt D, Metcalfe C, Rai M, Hollingworth W, Mills N, Beasant L, Parslow R, Kessler D, Macleod J, Stallard P, Knoop H, Van de Putte E, Nijhof S, Bleijenberg G, Crawley E.

Trials. 2019 Dec 19;20(1):750. doi: 10.1186/s13063-019-3895-1.

8.

Cost-Effectiveness of Sertraline in Primary Care According to Initial Severity and Duration of Depressive Symptoms: Findings from the PANDA RCT.

Hollingworth W, Fawsitt CG, Dixon P, Duffy L, Araya R, Peters TJ, Thom H, Welton NJ, Wiles N, Lewis G; PANDA Team.

Pharmacoecon Open. 2019 Nov 27. doi: 10.1007/s41669-019-00188-5. [Epub ahead of print]

9.

Laparoscopically assisted versus open oesophagectomy for patients with oesophageal cancer-the Randomised Oesophagectomy: Minimally Invasive or Open (ROMIO) study: protocol for a randomised controlled trial (RCT).

Brierley RC, Gaunt D, Metcalfe C, Blazeby JM, Blencowe NS, Jepson M, Berrisford RG, Avery KNL, Hollingworth W, Rice CT, Moure-Fernandez A, Wong N, Nicklin J, Skilton A, Boddy A, Byrne JP, Underwood T, Vohra R, Catton JA, Pursnani K, Melhado R, Alkhaffaf B, Krysztopik R, Lamb P, Culliford L, Rogers C, Howes B, Chalmers K, Cousins S, Elliott J, Donovan J, Heys R, Wickens RA, Wilkerson P, Hollowood A, Streets C, Titcomb D, Humphreys ML, Wheatley T, Sanders G, Ariyarathenam A, Kelly J, Noble F, Couper G, Skipworth RJE, Deans C, Ubhi S, Williams R, Bowrey D, Exon D, Turner P, Daya Shetty V, Chaparala R, Akhtar K, Farooq N, Parsons SL, Welch NT, Houlihan RJ, Smith J, Schranz R, Rea N, Cooke J, Williams A, Hindmarsh C, Maitland S, Howie L, Barham CP.

BMJ Open. 2019 Nov 19;9(11):e030907. doi: 10.1136/bmjopen-2019-030907.

10.

Group cognitive-behavioural programme to reduce the impact of rheumatoid arthritis fatigue: the RAFT RCT with economic and qualitative evaluations.

Hewlett S, Almeida C, Ambler N, Blair PS, Choy E, Dures E, Hammond A, Hollingworth W, Kadir B, Kirwan J, Plummer Z, Rooke C, Thorn J, Turner N, Pollock J.

Health Technol Assess. 2019 Oct;23(57):1-130. doi: 10.3310/hta23570.

11.

Evaluating the population impact of hepatitis C direct acting antiviral treatment as prevention for people who inject drugs (EPIToPe) - a natural experiment (protocol).

Hickman M, Dillon JF, Elliott L, De Angelis D, Vickerman P, Foster G, Donnan P, Eriksen A, Flowers P, Goldberg D, Hollingworth W, Ijaz S, Liddell D, Mandal S, Martin N, Beer LJZ, Drysdale K, Fraser H, Glass R, Graham L, Gunson RN, Hamilton E, Harris H, Harris M, Harris R, Heinsbroek E, Hope V, Horwood J, Inglis SK, Innes H, Lane A, Meadows J, McAuley A, Metcalfe C, Migchelsen S, Murray A, Myring G, Palmateer NE, Presanis A, Radley A, Ramsay M, Samartsidis P, Simmons R, Sinka K, Vojt G, Ward Z, Whiteley D, Yeung A, Hutchinson SJ.

BMJ Open. 2019 Sep 24;9(9):e029538. doi: 10.1136/bmjopen-2019-029538.

12.

The clinical effectiveness of sertraline in primary care and the role of depression severity and duration (PANDA): a pragmatic, double-blind, placebo-controlled randomised trial.

Lewis G, Duffy L, Ades A, Amos R, Araya R, Brabyn S, Button KS, Churchill R, Derrick C, Dowrick C, Gilbody S, Fawsitt C, Hollingworth W, Jones V, Kendrick T, Kessler D, Kounali D, Khan N, Lanham P, Pervin J, Peters TJ, Riozzie D, Salaminios G, Thomas L, Welton NJ, Wiles N, Woodhouse R, Lewis G.

Lancet Psychiatry. 2019 Nov;6(11):903-914. doi: 10.1016/S2215-0366(19)30366-9. Epub 2019 Sep 19.

13.

A peer-led physical activity intervention in schools for adolescent girls: a feasibility RCT.

Sebire SJ, Banfield K, Campbell R, Edwards MJ, Kipping R, Kadir B, Garfield K, Matthews J, Blair PS, Lyons RA, Hollingworth W, Jago R.

Southampton (UK): NIHR Journals Library; 2019 Sep.

14.

A process evaluation of the PLAN-A intervention (Peer-Led physical Activity iNtervention for Adolescent girls).

Sebire SJ, Banfield K, Jago R, Edwards MJ, Campbell R, Kipping R, Blair PS, Kadir B, Garfield K, Matthews J, Lyons RA, Hollingworth W.

BMC Public Health. 2019 Sep 2;19(1):1203. doi: 10.1186/s12889-019-7545-z.

15.

The usefulness of symptoms alone or combined for general practitioners in considering the diagnosis of a brain tumour: a case-control study using the clinical practice research database (CPRD) (2000-2014).

Ozawa M, Brennan PM, Zienius K, Kurian KM, Hollingworth W, Weller D, Grant R, Hamilton W, Ben-Shlomo Y.

BMJ Open. 2019 Aug 30;9(8):e029686. doi: 10.1136/bmjopen-2019-029686.

16.

Longitudinal study of use and cost of subacromial decompression surgery: the need for effective evaluation of surgical procedures to prevent overtreatment and wasted resources.

Jones T, Carr AJ, Beard D, Linton MJ, Rooshenas L, Donovan J, Hollingworth W.

BMJ Open. 2019 Aug 28;9(8):e030229. doi: 10.1136/bmjopen-2019-030229.

17.

Directly Acting Oral Anticoagulants for the Prevention of Stroke in Atrial Fibrillation in England and Wales: Cost-Effectiveness Model and Value of Information Analysis.

Thom HHZ, Hollingworth W, Sofat R, Wang Z, Fang W, Bodalia PN, Bryden PA, Davies PA, Caldwell DM, Dias S, Eaton D, Higgins JPT, Hingorani AD, Lopez-Lopez JA, Okoli GN, Richards A, Salisbury C, Savović J, Stephens-Boal A, Sterne JAC, Welton NJ.

MDM Policy Pract. 2019 Aug 17;4(2):2381468319866828. doi: 10.1177/2381468319866828. eCollection 2019 Jul-Dec.

18.

Pilot study of a two-arm non-randomized controlled cluster trial of a psychosocial intervention to improve late life depression in socioeconomically deprived areas of São Paulo, Brazil (PROACTIVE): feasibility study of a psychosocial intervention for late life depression in São Paulo.

Scazufca M, de Paula Couto MCP, Henrique MG, Mendes AV, Matijasevich A, Pereda PC, Franzin RM, Seabra AC, van de Ven P, Hollingworth W, Peters TJ, Araya R.

BMC Public Health. 2019 Aug 22;19(1):1152. doi: 10.1186/s12889-019-7495-5.

19.

Direct access CT for suspicion of brain tumour: an analysis of referral pathways in a population-based patient group.

Zienius K, Chak-Lam I, Park J, Ozawa M, Hamilton W, Weller D, Summers D, Porteous L, Mohiuddin S, Keeney E, Hollingworth W, Ben-Shlomo Y, Grant R, Brennan PM.

BMC Fam Pract. 2019 Aug 20;20(1):118. doi: 10.1186/s12875-019-1003-y.

20.

Child-care self-assessment to improve physical activity, oral health and nutrition for 2- to 4-year-olds: a feasibility cluster RCT.

Kipping R, Langford R, Brockman R, Wells S, Metcalfe C, Papadaki A, White J, Hollingworth W, Moore L, Ward D, Campbell R, Kadir B, Tinner L, Er V, Dias K, Busse H, Collingwood J, Nicholson A, Johnson L, Jago R.

Southampton (UK): NIHR Journals Library; 2019 Jul.

21.

Anaesthetic-analgesic ear drops to reduce antibiotic consumption in children with acute otitis media: the CEDAR RCT.

Hay AD, Downing H, Francis NA, Young GJ, Clement C, Harris SD, Ahern A, Schofield B, Thomas TE, Horwood J, Blair PS, Hollingworth W, Wilson V, Metcalfe C, Stoddart P, Nunez D, Lyttle MD, Little P, Moore MV.

Health Technol Assess. 2019 Jul;23(34):1-48. doi: 10.3310/hta23340.

22.

"What's fair to an individual is not always fair to a population": A qualitative study of patients and their health professionals using the Cancer Drugs Fund.

Chamberlain C, Owen-Smith A, MacKichan F, Donovan JL, Hollingworth W.

Health Policy. 2019 Aug;123(8):706-712. doi: 10.1016/j.healthpol.2019.05.022. Epub 2019 Jun 21.

23.

A physical activity, nutrition and oral health intervention in nursery settings: process evaluation of the NAP SACC UK feasibility cluster RCT.

Langford R, Jago R, White J, Moore L, Papadaki A, Hollingworth W, Metcalfe C, Ward D, Campbell R, Wells S, Kipping R.

BMC Public Health. 2019 Jul 3;19(1):865. doi: 10.1186/s12889-019-7102-9.

24.

Evaluation of 'care bundles' for patients with chronic obstructive pulmonary disease (COPD): a multisite study in the UK.

Morton K, MacNeill S, Sanderson E, Dixon P, King A, Jenkins S, Metcalfe C, Shaw A, Chalder M, Benger J, Hollingworth W, Calvert J, Purdy S.

BMJ Open Respir Res. 2019 May 30;6(1):e000425. doi: 10.1136/bmjresp-2019-000425. eCollection 2019.

25.

Cross-sectional analysis of physical activity in 2-4-year-olds in England with paediatric quality of life and family expenditure on physical activity.

Tinner L, Kipping R, White J, Jago R, Metcalfe C, Hollingworth W.

BMC Public Health. 2019 Jun 28;19(1):846. doi: 10.1186/s12889-019-7129-y.

26.

Care bundles to reduce re-admissions for patients with chronic obstructive pulmonary disease: a mixed-methods study.

Morton K, Sanderson E, Dixon P, King A, Jenkins S, MacNeill SJ, Shaw A, Metcalfe C, Chalder M, Hollingworth W, Benger J, Calvert J, Purdy S.

Southampton (UK): NIHR Journals Library; 2019 Jun.

27.

A workplace-based intervention to increase levels of daily physical activity: the Travel to Work cluster RCT.

Audrey S, Fisher H, Cooper A, Gaunt D, Metcalfe C, Garfield K, Hollingworth W, Procter S, Gabe-Walters M, Rodgers S, Gillison F, Davis A, Insall P.

Southampton (UK): NIHR Journals Library; 2019 May.

28.

Protocol for a cluster randomised controlled trial of a Peer-Led physical Activity iNtervention for Adolescent girls (PLAN-A).

Willis K, Tibbitts B, Sebire SJ, Reid T, MacNeill SJ, Sanderson E, Hollingworth W, Kandiyali R, Campbell R, Kipping RR, Jago R.

BMC Public Health. 2019 May 28;19(1):644. doi: 10.1186/s12889-019-7012-x.

29.

Evaluation of an intervention to promote walking during the commute to work: a cluster randomised controlled trial.

Audrey S, Fisher H, Cooper A, Gaunt D, Garfield K, Metcalfe C, Hollingworth W, Gillison F, Gabe-Walters M, Rodgers S, Davis AL, Insall P, Procter S.

BMC Public Health. 2019 Apr 24;19(1):427. doi: 10.1186/s12889-019-6791-4.

30.

The utility of diagnostic selective nerve root blocks in the management of patients with lumbar radiculopathy: a systematic review.

Beynon R, Elwenspoek MMC, Sheppard A, Higgins JN, Kolias AG, Laing RJ, Whiting P, Hollingworth W.

BMJ Open. 2019 Apr 20;9(4):e025790. doi: 10.1136/bmjopen-2018-025790.

31.

Choice of Prosthetic Implant Combinations in Total Hip Replacement: Cost-Effectiveness Analysis Using UK and Swedish Hip Joint Registries Data.

Fawsitt CG, Thom HHZ, Hunt LP, Nemes S, Blom AW, Welton NJ, Hollingworth W, López-López JA, Beswick AD, Burston A, Rolfson O, Garellick G, Marques EMR.

Value Health. 2019 Mar;22(3):303-312. doi: 10.1016/j.jval.2018.08.013. Epub 2018 Nov 2.

32.

Reducing arthritis fatigue impact: two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT).

Hewlett S, Almeida C, Ambler N, Blair PS, Choy EH, Dures E, Hammond A, Hollingworth W, Kadir B, Kirwan JR, Plummer Z, Rooke C, Thorn J, Turner N, Pollock J; RAFT Study Group.

Ann Rheum Dis. 2019 Apr;78(4):465-472. doi: 10.1136/annrheumdis-2018-214469. Epub 2019 Feb 6.

33.

Ten-year follow-up of a randomised trial of drainage, irrigation and fibrinolytic therapy (DRIFT) in infants with post-haemorrhagic ventricular dilatation.

Luyt K, Jary S, Lea C, Young GJ, Odd D, Miller H, Kmita G, Williams C, Blair PS, Fernández AM, Hollingworth W, Morgan M, Smith-Collins A, Thai NJ, Walker-Cox S, Aquilina K, Pople I, Whitelaw A.

Health Technol Assess. 2019 Feb;23(4):1-116. doi: 10.3310/hta23040.

34.

Respiratory Tract Infections in Children in the Community: Prospective Online Inception Cohort Study.

Hay AD, Anderson E, Ingle S, Beck C, Hollingworth W.

Ann Fam Med. 2019 Jan;17(1):14-22. doi: 10.1370/afm.2327.

35.

The Association Between Adiposity and Inpatient Hospital Costs in the UK Biobank Cohort.

Dixon P, Davey Smith G, Hollingworth W.

Appl Health Econ Health Policy. 2019 Jun;17(3):359-370. doi: 10.1007/s40258-018-0450-2.

36.

Correction to: The help for people with money, employment or housing problems (HOPE) intervention: pilot randomised trial with mixed methods feasibility research.

Barnes MC, Haase AM, Scott LJ, Linton MJ, Bard AM, Donovan JL, Davies R, Dursley S, Williams S, Elliott D, Potokar J, Kapur N, Hawton K, O'Connor RC, Hollingworth W, Metcalfe C, Gunnell D.

Pilot Feasibility Stud. 2018 Nov 28;4:177. doi: 10.1186/s40814-018-0374-5. eCollection 2018.

37.

Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: the MIR RCT.

Kessler D, Burns A, Tallon D, Lewis G, MacNeill S, Round J, Hollingworth W, Chew-Graham C, Anderson I, Campbell J, Dickens C, Macleod U, Gilbody S, Davies S, Peters TJ, Wiles N.

Health Technol Assess. 2018 Nov;22(63):1-136. doi: 10.3310/hta22630.

38.

The help for people with money, employment or housing problems (HOPE) intervention: pilot randomised trial with mixed methods feasibility research.

Barnes MC, Haase AM, Scott LJ, Linton MJ, Bard AM, Donovan JL, Davies R, Dursley S, Williams S, Elliott D, Potokar J, Kapur N, Hawton K, O'Connor RC, Hollingworth W, Metcalfe C, Gunnell D.

Pilot Feasibility Stud. 2018 Nov 13;4:172. doi: 10.1186/s40814-018-0365-6. eCollection 2018. Erratum in: Pilot Feasibility Stud. 2018 Nov 28;4:177.

39.

Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR).

Kessler DS, MacNeill SJ, Tallon D, Lewis G, Peters TJ, Hollingworth W, Round J, Burns A, Chew-Graham CA, Anderson IM, Shepherd T, Campbell J, Dickens CM, Carter M, Jenkinson C, Macleod U, Gibson H, Davies S, Wiles NJ.

BMJ. 2018 Oct 31;363:k4218. doi: 10.1136/bmj.k4218. Erratum in: BMJ. 2018 Nov 15;363:k4691.

40.

Is teachers' mental health and wellbeing associated with students' mental health and wellbeing?

Harding S, Morris R, Gunnell D, Ford T, Hollingworth W, Tilling K, Evans R, Bell S, Grey J, Brockman R, Campbell R, Araya R, Murphy S, Kidger J.

J Affect Disord. 2019 Jan 1;242:180-187. doi: 10.1016/j.jad.2018.08.080. Epub 2018 Aug 17.

PMID:
30189355
41.

Breaking bread: examining the impact of policy changes in access to state-funded provisions of gluten-free foods in England.

Linton MJ, Jones T, Owen-Smith A, Payne RA, Coast J, Glynn J, Hollingworth W.

BMC Med. 2018 Aug 2;16(1):119. doi: 10.1186/s12916-018-1106-7.

42.

B-type natriuretic peptide-guided therapy for heart failure (HF): a systematic review and meta-analysis of individual participant data (IPD) and aggregate data.

Pufulete M, Maishman R, Dabner L, Higgins JPT, Rogers CA, Dayer M, MacLeod J, Purdy S, Hollingworth W, Schou M, Anguita-Sanchez M, Karlström P, Shochat MK, McDonagh T, Nightingale AK, Reeves BC.

Syst Rev. 2018 Jul 31;7(1):112. doi: 10.1186/s13643-018-0776-8.

43.

Core Items for a Standardized Resource Use Measure: Expert Delphi Consensus Survey.

Thorn JC, Brookes ST, Ridyard C, Riley R, Hughes DA, Wordsworth S, Noble SM, Thornton G, Hollingworth W.

Value Health. 2018 Jun;21(6):640-649. doi: 10.1016/j.jval.2017.06.011. Epub 2017 Sep 1.

44.

Results of a feasibility cluster randomised controlled trial of a peer-led school-based intervention to increase the physical activity of adolescent girls (PLAN-A).

Sebire SJ, Jago R, Banfield K, Edwards MJ, Campbell R, Kipping R, Blair PS, Kadir B, Garfield K, Matthews J, Lyons RA, Hollingworth W.

Int J Behav Nutr Phys Act. 2018 Jun 7;15(1):50. doi: 10.1186/s12966-018-0682-4.

45.

A pilot randomised controlled trial investigating a mindfulness-based stress reduction (MBSR) intervention in individuals with pulmonary arterial hypertension (PAH): the PATHWAYS study.

Tulloh RMR, Garratt V, Tagney J, Turner-Cobb J, Marques E, Greenwood R, Howard L, Gin-Sing W, Barton A, Ewings P, Craggs P, Hollingworth W.

Pilot Feasibility Stud. 2018 May 21;4:78. doi: 10.1186/s40814-018-0270-z. eCollection 2018.

46.

A cluster randomised controlled trial of the Wellbeing in Secondary Education (WISE) Project - an intervention to improve the mental health support and training available to secondary school teachers: protocol for an integrated process evaluation.

Evans R, Brockman R, Grey J, Bell S, Harding S, Gunnell D, Campbell R, Murphy S, Ford T, Hollingworth W, Tilling K, Morris R, Kadir B, Araya R, Kidger J.

Trials. 2018 May 4;19(1):270. doi: 10.1186/s13063-018-2617-4.

47.

Cost-Consequence Analysis Alongside a Randomised Controlled Trial of Hospital Versus Telephone Follow-Up after Treatment for Endometrial Cancer.

Dixon P, Beaver K, Williamson S, Sutton C, Martin-Hirsch P, Hollingworth W.

Appl Health Econ Health Policy. 2018 Jun;16(3):415-427. doi: 10.1007/s40258-018-0378-6.

48.

Investigating the effectiveness and cost-effectiveness of FITNET-NHS (Fatigue In Teenagers on the interNET in the NHS) compared to Activity Management to treat paediatric chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME): protocol for a randomised controlled trial.

Baos S, Brigden A, Anderson E, Hollingworth W, Price S, Mills N, Beasant L, Gaunt D, Garfield K, Metcalfe C, Parslow R, Downing H, Kessler D, Macleod J, Stallard P, Knoop H, Van de Putte E, Nijhof S, Bleijenberg G, Crawley E.

Trials. 2018 Feb 22;19(1):136. doi: 10.1186/s13063-018-2500-3.

49.

Symptoms in primary care with time to diagnosis of brain tumours.

Ozawa M, Brennan PM, Zienius K, Kurian KM, Hollingworth W, Weller D, Hamilton W, Grant R, Ben-Shlomo Y.

Fam Pract. 2018 Sep 18;35(5):551-558. doi: 10.1093/fampra/cmx139.

50.

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis.

López-López JA, Sterne JAC, Thom HHZ, Higgins JPT, Hingorani AD, Okoli GN, Davies PA, Bodalia PN, Bryden PA, Welton NJ, Hollingworth W, Caldwell DM, Savović J, Dias S, Salisbury C, Eaton D, Stephens-Boal A, Sofat R.

BMJ. 2017 Nov 28;359:j5058. doi: 10.1136/bmj.j5058. Review. Erratum in: BMJ. 2017 Dec 4;359:j5631. BMJ. 2018 May 23;361:k2295.

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