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Quantifying the Impact of Influenza Among Persons With Type 2 Diabetes Mellitus: A New Approach to Determine Medical and Physical Activity Impact.

Samson SI, Konty K, Lee WN, Quisel T, Foschini L, Kerr D, Liska J, Mills H, Hollingsworth R, Greenberg M, Beal AC.

J Diabetes Sci Technol. 2019 Nov 20:1932296819883340. doi: 10.1177/1932296819883340. [Epub ahead of print]


Hybrid clinical trials to generate real-world evidence: design considerations from a sponsor's perspective.

Zhu M, Sridhar S, Hollingsworth R, Chit A, Kimball T, Murmello K, Greenberg M, Gurunathan S, Chen J.

Contemp Clin Trials. 2019 Oct 24:105856. doi: 10.1016/j.cct.2019.105856. [Epub ahead of print]


Postharvest Population Reservoirs of Coffee Berry Borer (Coleoptera: Curculionidae) on Hawai'i Island.

Johnson MA, Fortna S, Hollingsworth RG, Manoukis NC.

J Econ Entomol. 2019 Dec 9;112(6):2833-2841. doi: 10.1093/jee/toz219.


Coffee berry borer (Hypothenemus hampei) (Coleoptera: Curculionidae) development across an elevational gradient on Hawai'i Island: Applying laboratory degree-day predictions to natural field populations.

Hamilton LJ, Hollingsworth RG, Sabado-Halpern M, Manoukis NC, Follett PA, Johnson MA.

PLoS One. 2019 Jul 17;14(7):e0218321. doi: 10.1371/journal.pone.0218321. eCollection 2019.


Turning the corner on therapeutic cancer vaccines.

Hollingsworth RE, Jansen K.

NPJ Vaccines. 2019 Feb 8;4:7. doi: 10.1038/s41541-019-0103-y. eCollection 2019. Review.


Immunogenicity of high-dose trivalent inactivated influenza vaccine: a systematic review and meta-analysis.

Samson SI, Leventhal PS, Salamand C, Meng Y, Seet BT, Landolfi V, Greenberg D, Hollingsworth R.

Expert Rev Vaccines. 2019 Mar;18(3):295-308. doi: 10.1080/14760584.2019.1575734. Epub 2019 Feb 13.


Immunoglobulin use in immune deficiency in the UK: a report of the UKPID and National Immunoglobulin Databases.

Shillitoe B, Hollingsworth R, Foster M, Garcez T, Guzman D, Edgar JD, Buckland M.

Clin Med (Lond). 2018 Oct;18(5):364-370. doi: 10.7861/clinmedicine.18-5-364.


Reactions of dicobalt octacarbonyl with dinucleating and mononucleating bis(imino)pyridine ligands.

Hollingsworth RL, Beattie JW, Grass A, Martin PD, Groysman S, Lord RL.

Dalton Trans. 2018 Nov 21;47(43):15353-15363. doi: 10.1039/c8dt03405b. Epub 2018 Oct 3.


Use of intravenous immunoglobulin for the treatment of autoimmune encephalitis: audit of the NHS experience.

Kinsella JA, Irani SR, Hollingsworth R, O'Shaughnessy D, Kane P, Foster M, Schott JM, Lunn MP.

JRSM Open. 2018 Sep 3;9(9):2054270418793021. doi: 10.1177/2054270418793021. eCollection 2018 Sep.


Cooperative bimetallic reactivity of a heterodinuclear molybdenum-copper model of Mo-Cu CODH.

Hollingsworth TS, Hollingsworth RL, Lord RL, Groysman S.

Dalton Trans. 2018 Jul 31;47(30):10017-10024. doi: 10.1039/c8dt02323a.


The Hawaii Protocol for Scientific Monitoring of Coffee Berry Borer: a Model for Coffee Agroecosystems Worldwide.

Johnson MA, Hollingsworth R, Fortna S, Aristizábal LF, Manoukis NC.

J Vis Exp. 2018 Mar 19;(133). doi: 10.3791/57204.


World bleeding disorders registry: The pilot study.

Coffin D, Herr C, O'Hara J, Diop S, Hollingsworth R, Srivastava A, Lillicrap D, van den Berg HM, Iorio A, Pierce GF.

Haemophilia. 2018 May;24(3):e113-e116. doi: 10.1111/hae.13431. Epub 2018 Feb 1. No abstract available.


Nursing review section of Surgical Neurology International: Part 1 lumbar disc disease.

Epstein NE, Hollingsworth RD.

Surg Neurol Int. 2017 Dec 11;8:301. doi: 10.4103/sni.sni_151_17. eCollection 2017. Review.


Quadrivalent inactivated influenza vaccine (VaxigripTetra™).

Gresset-Bourgeois V, Leventhal PS, Pepin S, Hollingsworth R, Kazek-Duret MP, De Bruijn I, Samson SI.

Expert Rev Vaccines. 2018 Jan;17(1):1-11. doi: 10.1080/14760584.2018.1407650. Epub 2017 Nov 27. Review.


Integrated Pest Management of Coffee Berry Borer in Hawaii and Puerto Rico: Current Status and Prospects.

Aristizábal LF, Johnson M, Shriner S, Hollingsworth R, Manoukis NC, Myers R, Bayman P, Arthurs SP.

Insects. 2017 Nov 14;8(4). pii: E123. doi: 10.3390/insects8040123.


Nursing review of diagnosis and treatment of lumbar degenerative spondylolisthesis.

Epstein NE, Hollingsworth RD.

Surg Neurol Int. 2017 Oct 10;8:246. doi: 10.4103/sni.sni_276_17. eCollection 2017.


Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency.

Dosch J, Ziemke E, Wan S, Luker K, Welling T, Hardiman K, Fearon E, Thomas S, Flynn M, Rios-Doria J, Hollingsworth R, Herbst R, Hurt E, Sebolt-Leopold J.

Oncotarget. 2017 May 10;8(39):65090-65099. doi: 10.18632/oncotarget.17780. eCollection 2017 Sep 12.


Flight Activity and Field Infestation Relationships for Coffee Berry Borer in Commercial Coffee Plantations in Kona and Kau Districts, Hawaii.

Aristizábal LF, Shriner S, Hollingsworth R, Arthurs S.

J Econ Entomol. 2017 Dec 5;110(6):2421-2427. doi: 10.1093/jee/tox215.


The haemtrack home therapy reporting system: Design, implementation, strengths and weaknesses: A report from UK Haemophilia Centre Doctors Organisation.

Hay CRM, Xiang H, Scott M, Collins PW, Liesner R, Dolan G, Hollingsworth R.

Haemophilia. 2017 Sep;23(5):728-735. doi: 10.1111/hae.13287. Epub 2017 Aug 14.


Nursing Review Section of Surgical Neurology International Part 2: Lumbar Spinal Stenosis.

Epstein NE, Hollingsworth RD.

Surg Neurol Int. 2017 Jul 7;8:139. doi: 10.4103/sni.sni_150_17. eCollection 2017. Review.


Nursing review section of surgical neurology international: Evaluation of cervical disc disease and when surgery is warranted.

Epstein NE, Hollingsworth RD.

Surg Neurol Int. 2017 Jul 7;8:136. doi: 10.4103/sni.sni_182_17. eCollection 2017. Review.


Nursing review section of surgical neurology international: Part 1 lumbar disc disease.

Epstein NE, Hollingsworth RD.

Surg Neurol Int. 2017 Jul 7;8:135. doi: 10.4103/sni.sni_177_17. eCollection 2017.


Survey of distribution of seasonal influenza vaccine doses in 201 countries (2004-2015): The 2003 World Health Assembly resolution on seasonal influenza vaccination coverage and the 2009 influenza pandemic have had very little impact on improving influenza control and pandemic preparedness.

Palache A, Abelin A, Hollingsworth R, Cracknell W, Jacobs C, Tsai T, Barbosa P; IFPMA Influenza Vaccine Supply (IFPMA IVS) task force.

Vaccine. 2017 Aug 24;35(36):4681-4686. doi: 10.1016/j.vaccine.2017.07.053. Epub 2017 Jul 25.


Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine-Conjugated Antibody-Drug Conjugate Targeting 5T4.

Harper J, Lloyd C, Dimasi N, Toader D, Marwood R, Lewis L, Bannister D, Jovanovic J, Fleming R, D'Hooge F, Mao S, Marrero AM, Korade M 3rd, Strout P, Xu L, Chen C, Wetzel L, Breen S, van Vlerken-Ysla L, Jalla S, Rebelatto M, Zhong H, Hurt EM, Hinrichs MJ, Huang K, Howard PW, Tice DA, Hollingsworth RE, Herbst R, Kamal A.

Mol Cancer Ther. 2017 Aug;16(8):1576-1587. doi: 10.1158/1535-7163.MCT-16-0825. Epub 2017 May 18.


Antibody-Drug Conjugates Bearing Pyrrolobenzodiazepine or Tubulysin Payloads Are Immunomodulatory and Synergize with Multiple Immunotherapies.

Rios-Doria J, Harper J, Rothstein R, Wetzel L, Chesebrough J, Marrero A, Chen C, Strout P, Mulgrew K, McGlinchey K, Fleming R, Bezabeh B, Meekin J, Stewart D, Kennedy M, Martin P, Buchanan A, Dimasi N, Michelotti E, Hollingsworth R.

Cancer Res. 2017 May 15;77(10):2686-2698. doi: 10.1158/0008-5472.CAN-16-2854. Epub 2017 Mar 10.


Divergent reactivity of a new dinuclear xanthene-bridged bis(iminopyridine) di-nickel complex with alkynes.

Hollingsworth RL, Bheemaraju A, Lenca N, Lord RL, Groysman S.

Dalton Trans. 2017 May 2;46(17):5605-5616. doi: 10.1039/c6dt04532d.


Immunoglobulin therapy.

Johnston SL, Hollingsworth R.

Clin Med (Lond). 2016 Dec;16(6):576-579. Review.


5T4-Targeted Therapy Ablates Cancer Stem Cells and Prevents Recurrence of Head and Neck Squamous Cell Carcinoma.

Kerk SA, Finkel KA, Pearson AT, Warner KA, Zhang Z, Nör F, Wagner VP, Vargas PA, Wicha MS, Hurt EM, Hollingsworth RE, Tice DA, Nör JE.

Clin Cancer Res. 2017 May 15;23(10):2516-2527. doi: 10.1158/1078-0432.CCR-16-1834. Epub 2016 Oct 25.


A review of percutaneous transhepatic biliary drainage at a tertiary referral centre.

Asadi H, Hollingsworth R, Pennycooke K, Thanaratnam P, Given M, Keeling A, Lee M.

Clin Radiol. 2016 Dec;71(12):1312.e7-1312.e11. doi: 10.1016/j.crad.2016.05.013. Epub 2016 Jun 28.


Targeting CD73 in the tumor microenvironment with MEDI9447.

Hay CM, Sult E, Huang Q, Mulgrew K, Fuhrmann SR, McGlinchey KA, Hammond SA, Rothstein R, Rios-Doria J, Poon E, Holoweckyj N, Durham NM, Leow CC, Diedrich G, Damschroder M, Herbst R, Hollingsworth RE, Sachsenmeier KF.

Oncoimmunology. 2016 Jul 11;5(8):e1208875. doi: 10.1080/2162402X.2016.1208875. eCollection 2016 Aug.


Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations.

Ladd B, Mazzola AM, Bihani T, Lai Z, Bradford J, Collins M, Barry E, Goeppert AU, Weir HM, Hearne K, Renshaw JG, Mohseni M, Hurt E, Jalla S, Bao H, Hollingsworth R, Reimer C, Zinda M, Fawell S, D'Cruz CM.

Oncotarget. 2016 Aug 23;7(34):54120-54136. doi: 10.18632/oncotarget.10852.


Overproduction of IGF-2 drives a subset of colorectal cancer cells, which specifically respond to an anti-IGF therapeutic antibody and combination therapies.

Zhong H, Fazenbaker C, Chen C, Breen S, Huang J, Yao X, Ren P, Yao Y, Herbst R, Hollingsworth RE.

Oncogene. 2017 Feb 9;36(6):797-806. doi: 10.1038/onc.2016.248. Epub 2016 Jul 11.


Rational design, biophysical and biological characterization of site-specific antibody-tubulysin conjugates with improved stability, efficacy and pharmacokinetics.

Thompson P, Fleming R, Bezabeh B, Huang F, Mao S, Chen C, Harper J, Zhong H, Gao X, Yu XQ, Hinrichs MJ, Reed M, Kamal A, Strout P, Cho S, Woods R, Hollingsworth RE, Dixit R, Wu H, Gao C, Dimasi N.

J Control Release. 2016 Aug 28;236:100-16. doi: 10.1016/j.jconrel.2016.06.025. Epub 2016 Jun 18.


Therapeutic Efficacy of Cancer Stem Cell Vaccines in the Adjuvant Setting.

Hu Y, Lu L, Xia Y, Chen X, Chang AE, Hollingsworth RE, Hurt E, Owen J, Moyer JS, Prince ME, Dai F, Bao Y, Wang Y, Whitfield J, Xia JC, Huang S, Wicha MS, Li Q.

Cancer Res. 2016 Aug 15;76(16):4661-72. doi: 10.1158/0008-5472.CAN-15-2664. Epub 2016 Jun 20.


IL-6 Inhibition With MEDI5117 Decreases The Fraction of Head and Neck Cancer Stem Cells and Prevents Tumor Recurrence.

Finkel KA, Warner KA, Kerk S, Bradford CR, McLean SA, Prince ME, Zhong H, Hurt EM, Hollingsworth RE, Wicha MS, Tice DA, Nör JE.

Neoplasia. 2016 May;18(5):273-281. doi: 10.1016/j.neo.2016.03.004. Epub 2016 Apr 15.


Pneumococcal conjugate vaccine herd effects on non-invasive pneumococcal pneumonia in elderly.

van Werkhoven CH, Hollingsworth RC, Huijts SM, Bolkenbaas M, Webber C, Patterson S, Sanders EA, Bonten MJ.

Vaccine. 2016 Jun 14;34(28):3275-82. doi: 10.1016/j.vaccine.2016.05.002. Epub 2016 May 9.


A Potent HER3 Monoclonal Antibody That Blocks Both Ligand-Dependent and -Independent Activities: Differential Impacts of PTEN Status on Tumor Response.

Xiao Z, Carrasco RA, Schifferli K, Kinneer K, Tammali R, Chen H, Rothstein R, Wetzel L, Yang C, Chowdhury P, Tsui P, Steiner P, Jallal B, Herbst R, Hollingsworth RE, Tice DA.

Mol Cancer Ther. 2016 Apr;15(4):689-701. doi: 10.1158/1535-7163.MCT-15-0555. Epub 2016 Feb 15.


A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors.

Zhong H, Davis A, Ouzounova M, Carrasco RA, Chen C, Breen S, Chang YS, Huang J, Liu Z, Yao Y, Hurt E, Moisan J, Fung M, Tice DA, Clouthier SG, Xiao Z, Wicha MS, Korkaya H, Hollingsworth RE.

Cancer Res. 2016 Jan 15;76(2):480-90. doi: 10.1158/0008-5472.CAN-15-0883. Epub 2016 Jan 7.


HER2 drives Mucin-like 1 to control proliferation in breast cancer cells.

Conley SJ, Bosco EE, Tice DA, Hollingsworth RE, Herbst R, Xiao Z.

Oncogene. 2016 Aug 11;35(32):4225-34. doi: 10.1038/onc.2015.487. Epub 2016 Jan 4.


Developing an automated process of uploading immunoglobulin batch numbers to the UK National Immunoglobulin Database.

Denman S, Catt S, Hollingsworth R.

Eur J Hosp Pharm. 2016 Jan;23(1):54-56. doi: 10.1136/ejhpharm-2015-000654. Epub 2015 Mar 6.


Doxil synergizes with cancer immunotherapies to enhance antitumor responses in syngeneic mouse models.

Rios-Doria J, Durham N, Wetzel L, Rothstein R, Chesebrough J, Holoweckyj N, Zhao W, Leow CC, Hollingsworth R.

Neoplasia. 2015 Aug;17(8):661-70. doi: 10.1016/j.neo.2015.08.004.


Inhibitor development in non-severe haemophilia across Europe.

Fischer K, Iorio A, Lassila R, Peyvandi F, Calizzani G, Gatt A, Lambert T, Windyga J, Gilman EA, Hollingsworth R, Makris M; EUHASS Participants.

Thromb Haemost. 2015 Oct;114(4):670-5. doi: 10.1160/TH14-12-1044. Epub 2015 Aug 13. Erratum in: Thromb Haemost. 2016 Mar;115(3):684. Hollingsworth, R [Added].


Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling.

Sandercock AM, Rust S, Guillard S, Sachsenmeier KF, Holoweckyj N, Hay C, Flynn M, Huang Q, Yan K, Herpers B, Price LS, Soden J, Freeth J, Jermutus L, Hollingsworth R, Minter R.

Mol Cancer. 2015 Jul 31;14:147. doi: 10.1186/s12943-015-0415-0.


FVIII inhibitor development according to concentrate: data from the EUHASS registry excluding overlap with other studies.

Fischer K, Iorio A, Hollingsworth R, Makris M; EUHASS collaborators.

Haemophilia. 2016 Jan;22(1):e36-8. doi: 10.1111/hae.12764. Epub 2015 Jul 24. No abstract available.


Spinal surgeons need to read patients' studies to avoid missing pathology.

Epstein NE, Hollingsworth RD, Silvergleid R.

Surg Neurol Int. 2015 Jun 25;6(Suppl 10):S313-7. doi: 10.4103/2152-7806.159379. eCollection 2015.


In Vivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors.

Pore N, Jalla S, Liu Z, Higgs B, Sorio C, Scarpa A, Hollingsworth R, Tice DA, Michelotti E.

Neoplasia. 2015 Jun;17(6):473-80. doi: 10.1016/j.neo.2015.05.001.


Noninvasive Streptococcus pneumoniae serotypes recovered from hospitalized adult patients in the United States in 2009 to 2012.

Mendes RE, Hollingsworth RC, Costello A, Jones RN, Isturiz RE, Hewlett D Jr, Farrell DJ.

Antimicrob Agents Chemother. 2015 Sep;59(9):5595-601. doi: 10.1128/AAC.00182-15. Epub 2015 Jun 29.


Interleukin-6 Stimulates Defective Angiogenesis.

Gopinathan G, Milagre C, Pearce OM, Reynolds LE, Hodivala-Dilke K, Leinster DA, Zhong H, Hollingsworth RE, Thompson R, Whiteford JR, Balkwill F.

Cancer Res. 2015 Aug 1;75(15):3098-107. doi: 10.1158/0008-5472.CAN-15-1227. Epub 2015 Jun 16.


C5 Nerve root palsies following cervical spine surgery: A review.

Epstein NE, Hollingsworth R.

Surg Neurol Int. 2015 May 7;6(Suppl 4):S154-63. doi: 10.4103/2152-7806.156556. eCollection 2015.


Diagnosis and management of traumatic cervical central spinal cord injury: A review.

Epstein NE, Hollingsworth R.

Surg Neurol Int. 2015 May 7;6(Suppl 4):S140-53. doi: 10.4103/2152-7806.156552. eCollection 2015.

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