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Items: 31


Epitranscriptomic Addition of m5C to HIV-1 Transcripts Regulates Viral Gene Expression.

Courtney DG, Tsai K, Bogerd HP, Kennedy EM, Law BA, Emery A, Swanstrom R, Holley CL, Cullen BR.

Cell Host Microbe. 2019 Aug 14;26(2):217-227.e6. doi: 10.1016/j.chom.2019.07.005.


Modification of messenger RNA by 2'-O-methylation regulates gene expression in vivo.

Elliott BA, Ho HT, Ranganathan SV, Vangaveti S, Ilkayeva O, Abou Assi H, Choi AK, Agris PF, Holley CL.

Nat Commun. 2019 Jul 30;10(1):3401. doi: 10.1038/s41467-019-11375-7.


Cardiac Allograft Vasculopathy: A Formidable Foe.

Patel CB, Holley CL.

J Am Coll Cardiol. 2019 Jul 9;74(1):52-53. doi: 10.1016/j.jacc.2019.05.028. No abstract available.


Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression.

Courtney DG, Chalem A, Bogerd HP, Law BA, Kennedy EM, Holley CL, Cullen BR.

MBio. 2019 Jun 11;10(3). pii: e01209-19. doi: 10.1128/mBio.01209-19.


NLRC3 Restrains Responses to a T.

Holley CL, Coll RC, Schroder K.

Immunity. 2018 Dec 18;49(6):989-991. doi: 10.1016/j.immuni.2018.12.003.


Author Correction: Mitochondrial DNA synthesis fuels NLRP3 inflammasome.

Coll RC, Holley CL, Schroder K.

Cell Res. 2018 Dec;28(12):1202. doi: 10.1038/s41422-018-0112-9.


Mitochondrial DNA synthesis fuels NLRP3 activation.

Coll RC, Holley CL, Schroder K.

Cell Res. 2018 Nov;28(11):1046-1047. doi: 10.1038/s41422-018-0093-8. No abstract available. Erratum in: Cell Res. 2018 Dec;28(12):1202. Title corrected.


N6-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression.

Fry NJ, Law BA, Ilkayeva OR, Carraway KR, Holley CL, Mansfield KD.

Oncotarget. 2018 Jul 27;9(58):31231-31243. doi: 10.18632/oncotarget.25782. eCollection 2018 Jul 27.


Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion.

Monteleone M, Stanley AC, Chen KW, Brown DL, Bezbradica JS, von Pein JB, Holley CL, Boucher D, Shakespear MR, Kapetanovic R, Rolfes V, Sweet MJ, Stow JL, Schroder K.

Cell Rep. 2018 Aug 7;24(6):1425-1433. doi: 10.1016/j.celrep.2018.07.027.


Long-range function of secreted small nucleolar RNAs that direct 2'-O-methylation.

Rimer JM, Lee J, Holley CL, Crowder RJ, Chen DL, Hanson PI, Ory DS, Schaffer JE.

J Biol Chem. 2018 Aug 24;293(34):13284-13296. doi: 10.1074/jbc.RA118.003410. Epub 2018 Jul 6.


Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.

Boucher D, Monteleone M, Coll RC, Chen KW, Ross CM, Teo JL, Gomez GA, Holley CL, Bierschenk D, Stacey KJ, Yap AS, Bezbradica JS, Schroder K.

J Exp Med. 2018 Mar 5;215(3):827-840. doi: 10.1084/jem.20172222. Epub 2018 Feb 6.


Sulfonylureas as Concomitant Insulin Secretagogues and NLRP3 Inflammasome Inhibitors.

Hill JR, Coll RC, Sue N, Reid JC, Dou J, Holley CL, Pelingon R, Dickinson JB, Biden TJ, Schroder K, Cooper MA, Robertson AAB.

ChemMedChem. 2017 Sep 7;12(17):1449-1457. doi: 10.1002/cmdc.201700270. Epub 2017 Aug 4.


N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs.

Fry NJ, Law BA, Ilkayeva OR, Holley CL, Mansfield KD.

RNA. 2017 Sep;23(9):1444-1455. doi: 10.1261/rna.061044.117. Epub 2017 Jun 13.


Rpl13a small nucleolar RNAs regulate systemic glucose metabolism.

Lee J, Harris AN, Holley CL, Mahadevan J, Pyles KD, Lavagnino Z, Scherrer DE, Fujiwara H, Sidhu R, Zhang J, Huang SC, Piston DW, Remedi MS, Urano F, Ory DS, Schaffer JE.

J Clin Invest. 2016 Dec 1;126(12):4616-4625. doi: 10.1172/JCI88069. Epub 2016 Nov 7.


The Challenges of Bedside-to-Bench Research in Pediatric Cardiology.

Holley CL.

J Card Fail. 2017 Jan;23(1):81-82. doi: 10.1016/j.cardfail.2016.09.021. Epub 2016 Sep 30. No abstract available.


N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection.

Gokhale NS, McIntyre ABR, McFadden MJ, Roder AE, Kennedy EM, Gandara JA, Hopcraft SE, Quicke KM, Vazquez C, Willer J, Ilkayeva OR, Law BA, Holley CL, Garcia-Blanco MA, Evans MJ, Suthar MS, Bradrick SS, Mason CE, Horner SM.

Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.


The MisR Response Regulator Is Necessary for Intrinsic Cationic Antimicrobial Peptide and Aminoglycoside Resistance in Neisseria gonorrhoeae.

Kandler JL, Holley CL, Reimche JL, Dhulipala V, Balthazar JT, Muszyński A, Carlson RW, Shafer WM.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):4690-700. doi: 10.1128/AAC.00823-16. Print 2016 Aug.


Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation.

Masters SL, Lagou V, Jéru I, Baker PJ, Van Eyck L, Parry DA, Lawless D, De Nardo D, Garcia-Perez JE, Dagley LF, Holley CL, Dooley J, Moghaddas F, Pasciuto E, Jeandel PY, Sciot R, Lyras D, Webb AI, Nicholson SE, De Somer L, van Nieuwenhove E, Ruuth-Praz J, Copin B, Cochet E, Medlej-Hashim M, Megarbane A, Schroder K, Savic S, Goris A, Amselem S, Wouters C, Liston A.

Sci Transl Med. 2016 Mar 30;8(332):332ra45. doi: 10.1126/scitranslmed.aaf1471.


Haemophilus ducreyi Seeks Alternative Carbon Sources and Adapts to Nutrient Stress and Anaerobiosis during Experimental Infection of Human Volunteers.

Gangaiah D, Zhang X, Baker B, Fortney KR, Gao H, Holley CL, Munson RS Jr, Liu Y, Spinola SM.

Infect Immun. 2016 Apr 22;84(5):1514-1525. doi: 10.1128/IAI.00048-16. Print 2016 May.


DksA and (p)ppGpp have unique and overlapping contributions to Haemophilus ducreyi pathogenesis in humans.

Holley CL, Zhang X, Fortney KR, Ellinger S, Johnson P, Baker B, Liu Y, Janowicz DM, Katz BP, Munson RS Jr, Spinola SM.

Infect Immun. 2015 Aug;83(8):3281-92. doi: 10.1128/IAI.00692-15. Epub 2015 Jun 8.


Prognostic utility of novel biomarkers of cardiovascular stress in patients with aortic stenosis undergoing valve replacement.

Lindman BR, Breyley JG, Schilling JD, Vatterott AM, Zajarias A, Maniar HS, Damiano RJ Jr, Moon MR, Lawton JS, Gage BF, Sintek MA, Aquino A, Holley CL, Patel NM, Lawler C, Lasala JM, Novak E.

Heart. 2015 Sep;101(17):1382-8. doi: 10.1136/heartjnl-2015-307742. Epub 2015 Jun 2.


Cytosolic accumulation of small nucleolar RNAs (snoRNAs) is dynamically regulated by NADPH oxidase.

Holley CL, Li MW, Scruggs BS, Matkovich SJ, Ory DS, Schaffer JE.

J Biol Chem. 2015 May 1;290(18):11741-8. doi: 10.1074/jbc.M115.637413. Epub 2015 Mar 19.


Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress.

Michel CI, Holley CL, Scruggs BS, Sidhu R, Brookheart RT, Listenberger LL, Behlke MA, Ory DS, Schaffer JE.

Cell Metab. 2011 Jul 6;14(1):33-44. doi: 10.1016/j.cmet.2011.04.009.


An introduction to small non-coding RNAs: miRNA and snoRNA.

Holley CL, Topkara VK.

Cardiovasc Drugs Ther. 2011 Apr;25(2):151-9. doi: 10.1007/s10557-011-6290-z. Review.


Macrovolt T-wave alternans and polymorphic ventricular tachycardia.

Holley CL, Cooper JA.

Circulation. 2009 Aug 4;120(5):445-6. doi: 10.1161/CIRCULATIONAHA.109.861633. No abstract available.


A GH3-like domain in reaper is required for mitochondrial localization and induction of IAP degradation.

Olson MR, Holley CL, Gan EC, Colón-Ramos DA, Kaplan B, Kornbluth S.

J Biol Chem. 2003 Nov 7;278(45):44758-68. Epub 2003 Aug 13.


Reaper is regulated by IAP-mediated ubiquitination.

Olson MR, Holley CL, Yoo SJ, Huh JR, Hay BA, Kornbluth S.

J Biol Chem. 2003 Feb 7;278(6):4028-34. Epub 2002 Nov 20.


Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition.

Holley CL, Olson MR, Colón-Ramos DA, Kornbluth S.

Nat Cell Biol. 2002 Jun;4(6):439-44.


RoBo-1, a novel member of the urokinase plasminogen activator receptor/CD59/Ly-6/snake toxin family selectively expressed in rat bone and growth plate cartilage.

Noel LS, Champion BR, Holley CL, Simmons CJ, Morris DC, Payne JA, Lean JM, Chambers TJ, Zaman G, Lanyon LE, Suva LJ, Miller LR.

J Biol Chem. 1998 Feb 13;273(7):3878-83.


Guidelines for treatment of malpractice claims reduces diversity.

Holley CL.

Healthc Financ Manage. 1985 Sep;39(9):58-66.


Audit committees: a new concept of responsibility in health care.

Holley CL, Westbay R.

Hosp Financ Manage. 1981 Jul;35(7):40-1, 43-4, 46. No abstract available.


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