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Items: 10

1.

Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor for treating acute myeloid leukemia.

Keegan K, Li C, Li Z, Ma J, Ragains M, Coberly S, Hollenback D, Eksterowicz J, Liang L, Weidner M, Huard J, Wang X, Alba G, Orf J, Lo MC, Zhao S, Ngo R, Chen A, Liu L, Carlson T, Quéva C, McGee LR, Medina J, Kamb A, Wickramasinghe D, Dai K.

Mol Cancer Ther. 2014 Apr;13(4):880-9. doi: 10.1158/1535-7163.MCT-13-0858. Epub 2014 Feb 13.

2.

Energy balance in congenital generalized lipodystrophy type I.

Taleban S, Carew HT, Dichek HL, Deeb SS, Hollenback D, Weigle DS, Cummings DE, Brunzell JD.

Metabolism. 2008 Aug;57(8):1155-61. doi: 10.1016/j.metabol.2008.04.008.

3.

Antileukemic activity of lysophosphatidic acid acyltransferase-beta inhibitor CT32228 in chronic myelogenous leukemia sensitive and resistant to imatinib.

La Rosée P, Jia T, Demehri S, Härtel N, de Vries P, Bonham L, Hollenback D, Singer JW, Melo JV, Druker BJ, Deininger MW.

Clin Cancer Res. 2006 Nov 1;12(21):6540-6.

4.

Effect of lysophosphatidic acid acyltransferase-beta inhibition in acute leukemia.

Douvas MG, Hogan KN, Ji Y, Hollenback D, Bonham L, Singer JW, Mitchell BS.

Leuk Res. 2006 Aug;30(8):1027-36. Epub 2006 Feb 20.

PMID:
16488473
5.

Substrate specificity of lysophosphatidic acid acyltransferase beta -- evidence from membrane and whole cell assays.

Hollenback D, Bonham L, Law L, Rossnagle E, Romero L, Carew H, Tompkins CK, Leung DW, Singer JW, White T.

J Lipid Res. 2006 Mar;47(3):593-604. Epub 2005 Dec 20.

6.

Diamino-C,N-diarylpyridine positional isomers as inhibitors of lysophosphatidic acid acyltransferase-beta.

Hong F, Hollenback D, Singer JW, Klein P.

Bioorg Med Chem Lett. 2005 Nov 1;15(21):4703-7.

PMID:
16143520
7.

Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas.

Pagel JM, Laugen C, Bonham L, Hackman RC, Hockenbery DM, Bhatt R, Hollenback D, Carew H, Singer JW, Press OW.

Clin Cancer Res. 2005 Jul 1;11(13):4857-66.

8.

Inhibition of lysophosphatidic acid acyltransferase beta disrupts proliferative and survival signals in normal cells and induces apoptosis of tumor cells.

Coon M, Ball A, Pound J, Ap S, Hollenback D, White T, Tulinsky J, Bonham L, Morrison DK, Finney R, Singer JW.

Mol Cancer Ther. 2003 Oct;2(10):1067-78.

9.

Lysophosphatidic acid acyltransferase-beta: a novel target for induction of tumour cell apoptosis.

Bonham L, Leung DW, White T, Hollenback D, Klein P, Tulinsky J, Coon M, de Vries P, Singer JW.

Expert Opin Ther Targets. 2003 Oct;7(5):643-61. Review.

PMID:
14498826
10.

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