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Exposure to anticholinergic and sedative medications using the Drug Burden Index and its association with vertigo, dizziness and balance problems in older people - Results from the KORA-FF4 Study.

Phillips A, Heier M, Strobl R, Linkohr B, Holle R, Peters A, Grill E.

Exp Gerontol. 2019 Jun 28;124:110644. doi: 10.1016/j.exger.2019.110644. [Epub ahead of print]


"Age matters"-German claims data indicate disparities in lung cancer care between elderly and young patients.

Walter J, Tufman A, Holle R, Schwarzkopf L.

PLoS One. 2019 Jun 12;14(6):e0217434. doi: 10.1371/journal.pone.0217434. eCollection 2019.


Vertigo and dizziness cause considerable more health care resource use and costs: results from the KORA FF4 study.

Wang X, Strobl R, Holle R, Seidl H, Peters A, Grill E.

J Neurol. 2019 May 22. doi: 10.1007/s00415-019-09386-x. [Epub ahead of print]


[Psychosocial Characteristic and Health Care for Unemployed Youths with Extreme Obesity - A Model Project].

Mühlig Y, Remy M, Holle R, Scherag A, Wabitsch M, Hebebrand J.

Psychother Psychosom Med Psychol. 2019 Apr 3. doi: 10.1055/a-0829-1995. [Epub ahead of print] German.


Psychometric properties and minimal important differences of SF-36 in Idiopathic Pulmonary Fibrosis.

Witt S, Krauss E, Barbero MAN, Müller V, Bonniaud P, Vancheri C, Wells AU, Vasakova M, Pesci A, Klepetko W, Seeger W, Crestani B, Leidl R, Holle R, Schwarzkopf L, Guenther A.

Respir Res. 2019 Mar 1;20(1):47. doi: 10.1186/s12931-019-1010-5.


Status quo bias and health behavior: findings from a cross-sectional study.

Karl FM, Holle R, Schwettmann L, Peters A, Laxy M.

Eur J Public Health. 2019 Feb 18. pii: ckz017. doi: 10.1093/eurpub/ckz017. [Epub ahead of print]


Cost-effectiveness analysis of case management for optimized antithrombotic treatment in German general practices compared to usual care - results from the PICANT trial.

Ulrich LR, Petersen JJ, Mergenthal K, Berghold A, Pregartner G, Holle R, Siebenhofer A.

Health Econ Rev. 2019 Feb 7;9(1):4. doi: 10.1186/s13561-019-0221-2.


Prevalence, Determinants, and Consequences of Vestibular Hypofunction. Results From the KORA-FF4 Survey.

Grill E, Heuberger M, Strobl R, Saglam M, Holle R, Linkohr B, Ladwig KH, Peters A, Schneider E, Jahn K, Lehnen N.

Front Neurol. 2018 Dec 7;9:1076. doi: 10.3389/fneur.2018.01076. eCollection 2018.


Incidence Rates of Type 2 Diabetes in People With Impaired Fasting Glucose (ADA vs. WHO Criteria) and Impaired Glucose Tolerance: Results From an Older Population (KORA S4/F4/FF4 Study).

Kowall B, Rathmann W, Bongaerts B, Kuss O, Stang A, Roden M, Herder C, Koenig W, Huth C, Heier M, Thorand B, Ladwig KH, Holle R, Meisinger C, Peters A.

Diabetes Care. 2019 Feb;42(2):e18-e20. doi: 10.2337/dc18-1473. Epub 2018 Dec 14. No abstract available.


Do adolescents with extreme obesity differ according to previous treatment seeking behavior? The Youth with Extreme obesity Study (YES) cohort.

Lennerz BS, Moss A, von Schnurbein J, Bickenbach A, Bollow E, Brandt S, Luetke-Brintrup D, Mühlig Y, Neef M, Ose C, Remy M, Stark R, Teuner C, Wolters B, Kiess W, Scherag A, Reinehr T, Holl RW, Holle R, Wiegand S, Hebebrand J, Wabitsch M.

Int J Obes (Lond). 2019 Jan;43(1):103-115. doi: 10.1038/s41366-018-0237-4. Epub 2018 Oct 27.


Time preference, outcome expectancy, and self-management in patients with type 2 diabetes.

Karl FM, Holle R, Schwettmann L, Peters A, Laxy M.

Patient Prefer Adherence. 2018 Sep 26;12:1937-1945. doi: 10.2147/PPA.S175045. eCollection 2018.


Time spent on self-management by people with diabetes: results from the population-based KORA survey in Germany.

Icks A, Haastert B, Arend W, Konein J, Thorand B, Holle R, Laxy M, Schunk M, Neumann A, Wasem J, Chernyak N.

Diabet Med. 2018 Sep 29. doi: 10.1111/dme.13832. [Epub ahead of print]


Wealth and occupation determine health deficit accumulation onset in Europe - Results from the SHARE study.

Stephan AJ, Strobl R, Holle R, Grill E.

Exp Gerontol. 2018 Nov;113:74-79. doi: 10.1016/j.exger.2018.09.021. Epub 2018 Sep 25.


Temporal trends in cardiovascular risk factors and performance of the Framingham Risk Score and the Pooled Cohort Equations.

Rospleszcz S, Thorand B, de Las Heras Gala T, Meisinger C, Holle R, Koenig W, Mansmann U, Peters A.

J Epidemiol Community Health. 2019 Jan;73(1):19-25. doi: 10.1136/jech-2018-211102. Epub 2018 Sep 27.


Usability of the Video Head Impulse Test: Lessons From the Population-Based Prospective KORA Study.

Heuberger M, Grill E, Saǧlam M, Ramaioli C, Müller M, Strobl R, Holle R, Peters A, Schneider E, Lehnen N.

Front Neurol. 2018 Aug 17;9:659. doi: 10.3389/fneur.2018.00659. eCollection 2018.


Exploring Different Strategies of Assessing the Economic Impact of Multiple Diabetes-Associated Complications and Their Interactions: A Large Claims-Based Study in Germany.

Kähm K, Laxy M, Schneider U, Holle R.

Pharmacoeconomics. 2019 Jan;37(1):63-74. doi: 10.1007/s40273-018-0699-1.


Association of individual and area-level socioeconomic conditions with quality of life and glycaemic control in 11- to 21-year-old adolescents with early-onset type 1 diabetes: a cross-sectional study.

Bächle C, Peneva A, Maier W, Castillo K, Stahl-Pehe A, Kuß O, Holle R, Hermann JM, Holl RW, Rosenbauer J.

Qual Life Res. 2018 Dec;27(12):3131-3136. doi: 10.1007/s11136-018-1949-6. Epub 2018 Aug 11.


Time trends in stroke incidence and in prevalence of risk factors in Southern Germany, 1989 to 2008/09.

Thiele I, Linseisen J, Heier M, Holle R, Kirchberger I, Peters A, Thorand B, Meisinger C.

Sci Rep. 2018 Aug 10;8(1):11981. doi: 10.1038/s41598-018-30350-8.


Direct healthcare costs associated with device assessed and self-reported physical activity: results from a cross-sectional population-based study.

Karl FM, Tremmel M, Luzak A, Schulz H, Peters A, Meisinger C, Holle R, Laxy M.

BMC Public Health. 2018 Aug 3;18(1):966. doi: 10.1186/s12889-018-5906-7.


Catastrophic expenditures and impoverishment due to out-of-pocket health payments in Kosovo.

Arenliu Qosaj F, Froeschl G, Berisha M, Bellaqa B, Holle R.

Cost Eff Resour Alloc. 2018 Jul 28;16:26. doi: 10.1186/s12962-018-0111-1. eCollection 2018.


Determinants for utilization and transitions of long-term care in adults 65+ in Germany: results from the longitudinal KORA-Age study.

Steinbeisser K, Grill E, Holle R, Peters A, Seidl H.

BMC Geriatr. 2018 Jul 31;18(1):172. doi: 10.1186/s12877-018-0860-x.


Determinants of adherence and effects on health-related quality of life after myocardial infarction: a prospective cohort study.

Krack G, Holle R, Kirchberger I, Kuch B, Amann U, Seidl H.

BMC Geriatr. 2018 Jun 7;18(1):136. doi: 10.1186/s12877-018-0827-y.


New indexes of body fat distribution and sex-specific risk of total and cause-specific mortality: a prospective cohort study.

Rost S, Freuer D, Peters A, Thorand B, Holle R, Linseisen J, Meisinger C.

BMC Public Health. 2018 Apr 2;18(1):427. doi: 10.1186/s12889-018-5350-8.


Compatibility of medication with PRISCUS criteria and identification of drug interactions in a large cohort of patients with COPD.

Graf J, Lucke T, Herrera R, Watz H, Holle R, Vogelmeier C, Ficker JH, Jörres RA.

Pulm Pharmacol Ther. 2018 Apr;49:123-129. doi: 10.1016/j.pupt.2018.01.011. Epub 2018 Feb 5.


Heterogeneous pattern of differences in respiratory parameters between elderly with either good or poor FEV1.

Karrasch S, Behr J, Huber RM, Nowak D, Peters A, Peters S, Holle R, Jörres RA, Schulz H; KORA Study Group.

BMC Pulm Med. 2018 Feb 6;18(1):27. doi: 10.1186/s12890-018-0582-z.


Rural versus urban differences in end-of-life care for lung cancer patients in Germany.

Walter J, Tufman A, Leidl R, Holle R, Schwarzkopf L.

Support Care Cancer. 2018 Jul;26(7):2275-2283. doi: 10.1007/s00520-018-4063-y. Epub 2018 Feb 4.


Regional differences in antihyperglycemic medication are not explained by individual socioeconomic status, regional deprivation, and regional health care services. Observational results from the German DIAB-CORE consortium.

Bächle C, Claessen H, Maier W, Tamayo T, Schunk M, Rückert-Eheberg IM, Holle R, Meisinger C, Moebus S, Jöckel KH, Schipf S, Völzke H, Hartwig S, Kluttig A, Kroll L, Linnenkamp U, Icks A.

PLoS One. 2018 Jan 25;13(1):e0191559. doi: 10.1371/journal.pone.0191559. eCollection 2018.


Health Care Costs Associated With Incident Complications in Patients With Type 2 Diabetes in Germany.

Kähm K, Laxy M, Schneider U, Rogowski WH, Lhachimi SK, Holle R.

Diabetes Care. 2018 May;41(5):971-978. doi: 10.2337/dc17-1763. Epub 2018 Jan 18.


Association of physical activity with lung function in lung-healthy German adults: results from the KORA FF4 study.

Luzak A, Karrasch S, Thorand B, Nowak D, Holle R, Peters A, Schulz H.

BMC Pulm Med. 2017 Dec 28;17(1):215. doi: 10.1186/s12890-017-0562-8.


The contribution of symptoms and comorbidities to the economic impact of COPD: an analysis of the German COSYCONET cohort.

Wacker ME, Kitzing K, Jörres RA, Leidl R, Schulz H, Karrasch S, Karch A, Koch A, Vogelmeier CF, Holle R.

Int J Chron Obstruct Pulmon Dis. 2017 Dec 4;12:3437-3448. doi: 10.2147/COPD.S141852. eCollection 2017.


The association between BMI and health-related quality of life in the US population: sex, age and ethnicity matters.

Laxy M, Teuner C, Holle R, Kurz C.

Int J Obes (Lond). 2018 Mar;42(3):318-326. doi: 10.1038/ijo.2017.252. Epub 2017 Oct 10.


The longitudinal association between change in physical activity, weight, and health-related quality of life: Results from the population-based KORA S4/F4/FF4 cohort study.

Rabel M, Meisinger C, Peters A, Holle R, Laxy M.

PLoS One. 2017 Sep 27;12(9):e0185205. doi: 10.1371/journal.pone.0185205. eCollection 2017.


The Non-Linear Relationship between BMI and Health Care Costs and the Resulting Cost Fraction Attributable to Obesity.

Laxy M, Stark R, Peters A, Hauner H, Holle R, Teuner CM.

Int J Environ Res Public Health. 2017 Aug 30;14(9). pii: E984. doi: 10.3390/ijerph14090984.


A Structured, Manual-Based Low-Level Intervention vs. Treatment as Usual Evaluated in a Randomized Controlled Trial for Adolescents with Extreme Obesity - the STEREO Trial.

Mühlig Y, Scherag A, Bickenbach A, Giesen U, Holl R, Holle R, Kiess W, Lennerz B, Lütke Brintrup D, Moss A, Neef M, Ose C, Reinehr T, Teuner CM, Wiegand S, Wolters B, Wabitsch M, Hebebrand J.

Obes Facts. 2017;10(4):341-352. doi: 10.1159/000475717. Epub 2017 Aug 9.


Male sex and poverty predict abrupt health decline: Deficit accumulation patterns and trajectories in the KORA-Age cohort study.

Stephan AJ, Strobl R, Holle R, Meisinger C, Schulz H, Ladwig KH, Thorand B, Peters A, Grill E.

Prev Med. 2017 Sep;102:31-38. doi: 10.1016/j.ypmed.2017.06.032. Epub 2017 Jun 27.


Healthcare use and expenditure for diabetes in Bangladesh.

Shariful Islam SM, Lechner A, Ferrari U, Laxy M, Seissler J, Brown J, Niessen LW, Holle R.

BMJ Glob Health. 2017 Jan 3;2(1):e000033. doi: 10.1136/bmjgh-2016-000033. eCollection 2017.


Relationship of hyperlipidemia to comorbidities and lung function in COPD: Results of the COSYCONET cohort.

Kahnert K, Lucke T, Huber RM, Behr J, Biertz F, Vogt A, Watz H, Alter P, Fähndrich S, Bals R, Holle R, Karrasch S, Söhler S, Wacker M, Ficker JH, Parhofer KG, Vogelmeier C, Jörres RA; COSYCONET consortium.

PLoS One. 2017 May 15;12(5):e0177501. doi: 10.1371/journal.pone.0177501. eCollection 2017.


Longitudinal change in health-related quality of life in people with prevalent and incident type 2 diabetes compared to diabetes-free controls.

Schunk M, Reitmeir P, Rückert-Eheberg IM, Tamayo T, Schipf S, Meisinger C, Peters A, Scheidt-Nave C, Ellert U, Hartwig S, Kluttig A, Völzke H, Holle R.

PLoS One. 2017 May 3;12(5):e0176895. doi: 10.1371/journal.pone.0176895. eCollection 2017.


Costs and health-related quality of life in Alpha-1-Antitrypsin Deficient COPD patients.

Karl FM, Holle R, Bals R, Greulich T, Jörres RA, Karch A, Koch A, Karrasch S, Leidl R, Schulz H, Vogelmeier C, Wacker ME; COSYCONET Study Group.

Respir Res. 2017 Apr 17;18(1):60. doi: 10.1186/s12931-017-0543-8.


Effects of Nursing Home Residency on Diabetes Care in Individuals with Dementia: An Explorative Analysis Based on German Claims Data.

Schwarzkopf L, Holle R, Schunk M.

Dement Geriatr Cogn Dis Extra. 2017 Feb 10;7(1):41-51. doi: 10.1159/000455071. eCollection 2017 Jan-Apr.


The 3-Year Cost-Effectiveness of a Nurse-Based Case Management versus Usual Care for Elderly Patients with Myocardial Infarction: Results from the KORINNA Follow-Up Study.

Seidl H, Hunger M, Meisinger C, Kirchberger I, Kuch B, Leidl R, Holle R.

Value Health. 2017 Mar;20(3):441-450. doi: 10.1016/j.jval.2016.10.001. Epub 2016 Dec 1.


Perceived risk of diabetes seriously underestimates actual diabetes risk: The KORA FF4 study.

Kowall B, Rathmann W, Stang A, Bongaerts B, Kuss O, Herder C, Roden M, Quante A, Holle R, Huth C, Peters A, Meisinger C.

PLoS One. 2017 Jan 31;12(1):e0171152. doi: 10.1371/journal.pone.0171152. eCollection 2017.


WMO World Record Lightning Extremes: Longest Reported Flash Distance and Longest Reported Flash Duration.

Lang TJ, Pédeboy S, Rison W, Cerveny RS, Montanyà J, Chauzy S, MacGorman DR, Holle RL, Ávila EE, Zhang Y, Carbin G, Mansell ER, Kuleshov Y, Peterson TC, Brunet M, Driouech F, Krahenbuhl DS.

Bull Am Meteorol Soc. 2017 Jun;98(6):1153-1168. doi: 10.1175/BAMS-D-16-0061.1. Epub 2016 Sep 13.


Transfer factor for carbon monoxide in patients with COPD and diabetes: results from the German COSYCONET cohort.

Kahnert K, Lucke T, Biertz F, Lechner A, Watz H, Alter P, Bals R, Behr J, Holle R, Huber RM, Karrasch S, Stubbe B, Wacker M, Söhler S, Wouters EF, Vogelmeier C, Jörres RA; COSYCONET study group.

Respir Res. 2017 Jan 13;18(1):14. doi: 10.1186/s12931-016-0499-0.


The Economic Burden of Obesity in Germany: Results from the Population-Based KORA Studies.

Yates N, Teuner CM, Hunger M, Holle R, Stark R, Laxy M, Hauner H, Peters A, Wolfenstetter SB.

Obes Facts. 2016;9(6):397-409. doi: 10.1159/000452248. Epub 2016 Dec 13.


Cost burden of type 2 diabetes in Germany: results from the population-based KORA studies.

Ulrich S, Holle R, Wacker M, Stark R, Icks A, Thorand B, Peters A, Laxy M.

BMJ Open. 2016 Nov 21;6(11):e012527. doi: 10.1136/bmjopen-2016-012527.


Systematic Analysis of Self-Reported Comorbidities in Large Cohort Studies - A Novel Stepwise Approach by Evaluation of Medication.

Lucke T, Herrera R, Wacker M, Holle R, Biertz F, Nowak D, Huber RM, Söhler S, Vogelmeier C, Ficker JH, Mückter H, Jörres RA; COSYCONET-Consortium.

PLoS One. 2016 Oct 28;11(10):e0163408. doi: 10.1371/journal.pone.0163408. eCollection 2016.


Quality of Diabetes Care in Germany Improved from 2000 to 2007 to 2014, but Improvements Diminished since 2007. Evidence from the Population-Based KORA Studies.

Laxy M, Knoll G, Schunk M, Meisinger C, Huth C, Holle R.

PLoS One. 2016 Oct 17;11(10):e0164704. doi: 10.1371/journal.pone.0164704. eCollection 2016.


DNA methylation-based measures of biological age: meta-analysis predicting time to death.

Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai PC, Roetker NS, Just AC, Demerath EW, Guan W, Bressler J, Fornage M, Studenski S, Vandiver AR, Moore AZ, Tanaka T, Kiel DP, Liang L, Vokonas P, Schwartz J, Lunetta KL, Murabito JM, Bandinelli S, Hernandez DG, Melzer D, Nalls M, Pilling LC, Price TR, Singleton AB, Gieger C, Holle R, Kretschmer A, Kronenberg F, Kunze S, Linseisen J, Meisinger C, Rathmann W, Waldenberger M, Visscher PM, Shah S, Wray NR, McRae AF, Franco OH, Hofman A, Uitterlinden AG, Absher D, Assimes T, Levine ME, Lu AT, Tsao PS, Hou L, Manson JE, Carty CL, LaCroix AZ, Reiner AP, Spector TD, Feinberg AP, Levy D, Baccarelli A, van Meurs J, Bell JT, Peters A, Deary IJ, Pankow JS, Ferrucci L, Horvath S.

Aging (Albany NY). 2016 Sep 28;8(9):1844-1865. doi: 10.18632/aging.101020.


IDGenerator: unique identifier generator for epidemiologic or clinical studies.

Olden M, Holle R, Heid IM, Stark K.

BMC Med Res Methodol. 2016 Sep 15;16:120. doi: 10.1186/s12874-016-0222-3.

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