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Change in Site of Children's Primary Care: A Longitudinal Population-Based Analysis.

Wasserman RC, Varni SE, Hollander MC, Harder VS.

Ann Fam Med. 2019 Sep;17(5):390-395. doi: 10.1370/afm.2416.


miR-130a and miR-145 reprogram Gr-1+CD11b+ myeloid cells and inhibit tumor metastasis through improved host immunity.

Ishii H, Vodnala SK, Achyut BR, So JY, Hollander MC, Greten TF, Lal A, Yang L.

Nat Commun. 2018 Jul 4;9(1):2611. doi: 10.1038/s41467-018-05023-9.


Consensus Treatment Plans for Chronic Nonbacterial Osteomyelitis Refractory to Nonsteroidal Antiinflammatory Drugs and/or With Active Spinal Lesions.

Zhao Y, Wu EY, Oliver MS, Cooper AM, Basiaga ML, Vora SS, Lee TC, Fox E, Amarilyo G, Stern SM, Dvergsten JA, Haines KA, Rouster-Stevens KA, Onel KB, Cherian J, Hausmann JS, Miettunen P, Cellucci T, Nuruzzaman F, Taneja A, Barron KS, Hollander MC, Lapidus SK, Li SC, Ozen S, Girschick H, Laxer RM, Dedeoglu F, Hedrich CM, Ferguson PJ; Chronic Nonbacterial Osteomyelitis/Chronic Recurrent Multifocal Osteomyelitis Study Group and the Childhood Arthritis and Rheumatology Research Alliance Scleroderma, Vasculitis, Autoinflammatory and Rare Diseases Subcommittee.

Arthritis Care Res (Hoboken). 2018 Aug;70(8):1228-1237. doi: 10.1002/acr.23462. Epub 2018 Jul 12. Review.


Attenuation of Myeloid-Specific TGFβ Signaling Induces Inflammatory Cerebrovascular Disease and Stroke.

Hollander MC, Latour LL, Yang D, Ishii H, Xiao Z, Min Y, Ray-Choudhury A, Munasinghe J, Merchant AS, Lin PC, Hallenbeck J, Boehm M, Yang L.

Circ Res. 2017 Dec 8;121(12):1360-1369. doi: 10.1161/CIRCRESAHA.116.310349. Epub 2017 Oct 19.


Platelet factor 4 is produced by subsets of myeloid cells in premetastatic lung and inhibits tumor metastasis.

Jian J, Pang Y, Yan HH, Min Y, Achyut BR, Hollander MC, Lin PC, Liang X, Yang L.

Oncotarget. 2017 Apr 25;8(17):27725-27739. doi: 10.18632/oncotarget.9486.


CXCR3 as a molecular target in breast cancer metastasis: inhibition of tumor cell migration and promotion of host anti-tumor immunity.

Zhu G, Yan HH, Pang Y, Jian J, Achyut BR, Liang X, Weiss JM, Wiltrout RH, Hollander MC, Yang L.

Oncotarget. 2015 Dec 22;6(41):43408-19. doi: 10.18632/oncotarget.6125.


Epidermal growth factor receptor as a novel molecular target for aggressive papillary tumors in the middle ear and temporal bone.

Kawabata S, Hollander MC, Munasinghe JP, Brinster LR, Mercado-Matos JR, Li J, Regales L, Pao W, Jänne PA, Wong KK, Butman JA, Lonser RR, Hansen MR, Gurgel RK, Vortmeyer AO, Dennis PA.

Oncotarget. 2015 May 10;6(13):11357-68.


Rapamycin prevents the development and progression of mutant epidermal growth factor receptor lung tumors with the acquired resistance mutation T790M.

Kawabata S, Mercado-Matos JR, Hollander MC, Donahue D, Wilson W 3rd, Regales L, Butaney M, Pao W, Wong KK, Jänne PA, Dennis PA.

Cell Rep. 2014 Jun 26;7(6):1824-32. doi: 10.1016/j.celrep.2014.05.039. Epub 2014 Jun 12.


Inhibition of lung tumorigenesis by metformin is associated with decreased plasma IGF-I and diminished receptor tyrosine kinase signaling.

Quinn BJ, Dallos M, Kitagawa H, Kunnumakkara AB, Memmott RM, Hollander MC, Gills JJ, Dennis PA.

Cancer Prev Res (Phila). 2013 Aug;6(8):801-10. doi: 10.1158/1940-6207.CAPR-13-0058-T. Epub 2013 Jun 14.


International consensus for provisions of quality-driven care in childhood-onset systemic lupus erythematosus.

Hollander MC, Sage JM, Greenler AJ, Pendl J, Avcin T, Espada G, Beresford MW, Henrickson M, Lee TL, Punaro M, Huggins J, Stevens AM, Klein-Gitelman MS, Brunner HI.

Arthritis Care Res (Hoboken). 2013 Sep;65(9):1416-23. doi: 10.1002/acr.21998. Review.


Synergistic effects of nelfinavir and bortezomib on proteotoxic death of NSCLC and multiple myeloma cells.

Kawabata S, Gills JJ, Mercado-Matos JR, Lopiccolo J, Wilson W 3rd, Hollander MC, Dennis PA.

Cell Death Dis. 2012 Jul 19;3:e353. doi: 10.1038/cddis.2012.87.


Nicotine does not enhance tumorigenesis in mutant K-ras-driven mouse models of lung cancer.

Maier CR, Hollander MC, Hobbs EA, Dogan I, Linnoila RI, Dennis PA.

Cancer Prev Res (Phila). 2011 Nov;4(11):1743-51. doi: 10.1158/1940-6207.CAPR-11-0365. Epub 2011 Oct 25.


Loss of cytoplasmic CDK1 predicts poor survival in human lung cancer and confers chemotherapeutic resistance.

Zhang C, Elkahloun AG, Robertson M, Gills JJ, Tsurutani J, Shih JH, Fukuoka J, Hollander MC, Harris CC, Travis WD, Jen J, Dennis PA.

PLoS One. 2011;6(8):e23849. doi: 10.1371/journal.pone.0023849. Epub 2011 Aug 24.


A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice.

Hollander MC, Zhou X, Maier CR, Patterson AD, Ding X, Dennis PA.

Carcinogenesis. 2011 Aug;32(8):1279-84. doi: 10.1093/carcin/bgr097. Epub 2011 May 30.


Expression signatures of the lipid-based Akt inhibitors phosphatidylinositol ether lipid analogues in NSCLC cells.

Zhang C, Elkahloun AG, Liao H, Delaney S, Saber B, Morrow B, Prendergast GC, Hollander MC, Gills JJ, Dennis PA.

Mol Cancer Ther. 2011 Jul;10(7):1137-48. doi: 10.1158/1535-7163.MCT-10-1028. Epub 2011 May 6.


PTEN loss in the continuum of common cancers, rare syndromes and mouse models.

Hollander MC, Blumenthal GM, Dennis PA.

Nat Rev Cancer. 2011 Apr;11(4):289-301. doi: 10.1038/nrc3037. Review. Erratum in: Nat Rev Cancer. 2011 Jun;11(6):458.


Akt1 deletion prevents lung tumorigenesis by mutant K-ras.

Hollander MC, Maier CR, Hobbs EA, Ashmore AR, Linnoila RI, Dennis PA.

Oncogene. 2011 Apr 14;30(15):1812-21. doi: 10.1038/onc.2010.556. Epub 2011 Jan 17.


A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis.

Granville CA, Memmott RM, Balogh A, Mariotti J, Kawabata S, Han W, Lopiccolo J, Foley J, Liewehr DJ, Steinberg SM, Fowler DH, Hollander MC, Dennis PA.

PLoS One. 2009;4(3):e5061. doi: 10.1371/journal.pone.0005061. Epub 2009 Mar 30.


Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas.

Wang Y, Digiovanna JJ, Stern JB, Hornyak TJ, Raffeld M, Khan SG, Oh KS, Hollander MC, Dennis PA, Kraemer KH.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6279-84. doi: 10.1073/pnas.0812401106. Epub 2009 Mar 27.


Strain-specific spontaneous and NNK-mediated tumorigenesis in Pten+/- mice.

Hollander MC, Balogh AR, Liwanag J, Han W, Linnoila RI, Anver MR, Dennis PA.

Neoplasia. 2008 Aug;10(8):866-72.


Inactivation of gadd45a sensitizes epithelial cancer cells to ionizing radiation in vivo resulting in prolonged survival.

Lu X, Yang C, Hill R, Yin C, Hollander MC, Fornace AJ Jr, Van Dyke T.

Cancer Res. 2008 May 15;68(10):3579-83. doi: 10.1158/0008-5472.CAN-07-5533.


Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo.

Gills JJ, Lopiccolo J, Tsurutani J, Shoemaker RH, Best CJ, Abu-Asab MS, Borojerdi J, Warfel NA, Gardner ER, Danish M, Hollander MC, Kawabata S, Tsokos M, Figg WD, Steeg PS, Dennis PA.

Clin Cancer Res. 2007 Sep 1;13(17):5183-94.


Index of suspicion.

Pingul M, Shah L, Denton S, Walenz E, Weisgerber M, Conley S, Li ST, Hollander MC.

Pediatr Rev. 2007 Jul;28(7):269-75. No abstract available.


Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.

Granville CA, Warfel N, Tsurutani J, Hollander MC, Robertson M, Fox SD, Veenstra TD, Issaq HJ, Linnoila RI, Dennis PA.

Clin Cancer Res. 2007 Apr 1;13(7):2281-9.


Effects of expression of p53 and Gadd45 on osmotic tolerance of renal inner medullary cells.

Cai Q, Dmitrieva NI, Ferraris JD, Michea LF, Salvador JM, Hollander MC, Fornace AJ Jr, Fenton RA, Burg MB.

Am J Physiol Renal Physiol. 2006 Aug;291(2):F341-9. Epub 2006 Apr 4.


Gadd34 requirement for normal hemoglobin synthesis.

Patterson AD, Hollander MC, Miller GF, Fornace AJ Jr.

Mol Cell Biol. 2006 Mar;26(5):1644-53.


Neural tube development requires the cooperation of p53- and Gadd45a-associated pathways.

Patterson AD, Hildesheim J, Fornace AJ Jr, Hollander MC.

Birth Defects Res A Clin Mol Teratol. 2006 Feb;76(2):129-32.


p21 controls patterning but not homologous recombination in RPE development.

Bishop AJ, Kosaras B, Hollander MC, Fornace A Jr, Sidman RL, Schiestl RH.

DNA Repair (Amst). 2006 Jan 5;5(1):111-20. Epub 2005 Sep 30.


Hematopoietic cells from Gadd45a- and Gadd45b-deficient mice are sensitized to genotoxic-stress-induced apoptosis.

Gupta M, Gupta SK, Balliet AG, Hollander MC, Fornace AJ, Hoffman B, Liebermann DA.

Oncogene. 2005 Nov 3;24(48):7170-9.


Deletion of XPC leads to lung tumors in mice and is associated with early events in human lung carcinogenesis.

Hollander MC, Philburn RT, Patterson AD, Velasco-Miguel S, Friedberg EC, Linnoila RI, Fornace AJ Jr.

Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13200-5. Epub 2005 Sep 2.


Genomic instability in Gadd45a-/- cells is coupled with S-phase checkpoint defects.

Hollander MC, Philburn RT, Patterson AD, Wyatt MA, Fornace AJ Jr.

Cell Cycle. 2005 May;4(5):704-9. Epub 2005 May 14.


Gadd45a acts as a modifier locus for lymphoblastic lymphoma.

Hollander MC, Patterson AD, Salvador JM, Anver MR, Hunger SP, Fornace AJ.

Leukemia. 2005 May;19(5):847-50.


Loss of Gadd45a does not modify the pulmonary response to oxidative stress.

Roper JM, Gehen SC, Staversky RJ, Hollander MC, Fornace AJ Jr, O'Reilly MA.

Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L663-71. Epub 2005 Jan 14.


Casein kinase 2- and protein kinase A-regulated adenomatous polyposis coli and beta-catenin cellular localization is dependent on p38 MAPK.

Hildesheim J, Salvador JM, Hollander MC, Fornace AJ Jr.

J Biol Chem. 2005 Apr 29;280(17):17221-6. Epub 2005 Jan 13.


Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure.

Wang X, Wang RH, Li W, Xu X, Hollander MC, Fornace AJ Jr, Deng CX.

J Biol Chem. 2004 Jul 9;279(28):29606-14. Epub 2004 May 3.


Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development.

Bishop AJ, Hollander MC, Kosaras B, Sidman RL, Fornace AJ Jr, Schiestl RH.

Cancer Res. 2003 Sep 1;63(17):5335-43.


Comparative analysis of the genetic structure and chromosomal mapping of the murine Gadd45g/CR6 gene.

Balliet AG, Hollander MC, Fornace AJ Jr, Hoffman B, Liebermann DA.

DNA Cell Biol. 2003 Jul;22(7):457-68.


Gadd34 functional domains involved in growth suppression and apoptosis.

Hollander MC, Poola-Kella S, Fornace AJ Jr.

Oncogene. 2003 Jun 19;22(25):3827-32.


Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a.

Bulavin DV, Kovalsky O, Hollander MC, Fornace AJ Jr.

Mol Cell Biol. 2003 Jun;23(11):3859-71.


Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53.

Hildesheim J, Bulavin DV, Anver MR, Alvord WG, Hollander MC, Vardanian L, Fornace AJ Jr.

Cancer Res. 2002 Dec 15;62(24):7305-15.


Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a.

Hollander MC, Fornace AJ Jr.

Oncogene. 2002 Sep 9;21(40):6228-33. Review.


Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome.

Salvador JM, Hollander MC, Nguyen AT, Kopp JB, Barisoni L, Moore JK, Ashwell JD, Fornace AJ Jr.

Immunity. 2002 Apr;16(4):499-508.


Dimethylbenzanthracene carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair and increased mutation frequency.

Hollander MC, Kovalsky O, Salvador JM, Kim KE, Patterson AD, Haines DC, Fornace AJ Jr.

Cancer Res. 2001 Mar 15;61(6):2487-91.


Activation of Gadd34 by diverse apoptotic signals and suppression of its growth inhibitory effects by apoptotic inhibitors.

Hollander MC, Sheikh MS, Yu K, Zhan Q, Iglesias M, Woodworth C, Fornace AJ Jr.

Int J Cancer. 2001 Feb 20;96(1):22-31.


p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes.

Smith ML, Ford JM, Hollander MC, Bortnick RA, Amundson SA, Seo YR, Deng CX, Hanawalt PC, Fornace AJ Jr.

Mol Cell Biol. 2000 May;20(10):3705-14.


Role of Gadd45 in apoptosis.

Sheikh MS, Hollander MC, Fornance AJ Jr.

Biochem Pharmacol. 2000 Jan 1;59(1):43-5. Review.


Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation.

Bulavin DV, Saito S, Hollander MC, Sakaguchi K, Anderson CW, Appella E, Fornace AJ Jr.

EMBO J. 1999 Dec 1;18(23):6845-54.


Genomic instability in Gadd45a-deficient mice.

Hollander MC, Sheikh MS, Bulavin DV, Lundgren K, Augeri-Henmueller L, Shehee R, Molinaro TA, Kim KE, Tolosa E, Ashwell JD, Rosenberg MP, Zhan Q, Fernández-Salguero PM, Morgan WF, Deng CX, Fornace AJ Jr.

Nat Genet. 1999 Oct;23(2):176-84.


GADD45 induction of a G2/M cell cycle checkpoint.

Wang XW, Zhan Q, Coursen JD, Khan MA, Kontny HU, Yu L, Hollander MC, O'Connor PM, Fornace AJ Jr, Harris CC.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3706-11.


Inhibitory effect of Bcl-2 on p53-mediated transactivation following genotoxic stress.

Zhan Q, Kontny U, Iglesias M, Alamo I Jr, Yu K, Hollander MC, Woodworth CD, Fornace AJ Jr.

Oncogene. 1999 Jan 14;18(2):297-304.

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