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Items: 1 to 50 of 538

1.

Risky lipids: refining the ceramide score that measures cardiovascular health.

Poss AM, Holland WL, Summers SA.

Eur Heart J. 2019 Aug 1. pii: ehz525. doi: 10.1093/eurheartj/ehz525. [Epub ahead of print] No abstract available.

PMID:
31369077
2.

Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.

Chaurasia B, Tippetts TS, Mayoral Monibas R, Liu J, Li Y, Wang L, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen X, Yao J, Nunes CN, Howard AD, Wang L, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA.

Science. 2019 Jul 26;365(6451):386-392. doi: 10.1126/science.aav3722. Epub 2019 Jul 4.

PMID:
31273070
3.

HABscope: A tool for use by citizen scientists to facilitate early warning of respiratory irritation caused by toxic blooms of Karenia brevis.

Hardison DR, Holland WC, Currier RD, Kirkpatrick B, Stumpf R, Fanara T, Burris D, Reich A, Kirkpatrick GJ, Litaker RW.

PLoS One. 2019 Jun 20;14(6):e0218489. doi: 10.1371/journal.pone.0218489. eCollection 2019.

4.

Listen to your heart when ceramide's calling for higher glucose.

Wilkerson JL, Summers SA, Holland WL.

EBioMedicine. 2019 Mar;41:3-4. doi: 10.1016/j.ebiom.2019.02.004. Epub 2019 Feb 7. No abstract available.

5.

PPARγ-K107 SUMOylation regulates insulin sensitivity but not adiposity in mice.

Katafuchi T, Holland WL, Kollipara RK, Kittler R, Mangelsdorf DJ, Kliewer SA.

Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):12102-12111. doi: 10.1073/pnas.1814522115. Epub 2018 Nov 12.

6.

Strong Heart, Low Ceramides.

Holland WL, Summers SA.

Diabetes. 2018 Aug;67(8):1457-1460. doi: 10.2337/dbi18-0018. No abstract available.

7.

A Hepatocyte FOXN3-α Cell Glucagon Axis Regulates Fasting Glucose.

Karanth S, Adams JD, Serrano MLA, Quittner-Strom EB, Simcox J, Villanueva CJ, Ozcan L, Holland WL, Yost HJ, Vella A, Schlegel A.

Cell Rep. 2018 Jul 10;24(2):312-319. doi: 10.1016/j.celrep.2018.06.039.

8.

The ceramide ratio: a predictor of cardiometabolic risk.

Tippetts TS, Holland WL, Summers SA.

J Lipid Res. 2018 Sep;59(9):1549-1550. doi: 10.1194/jlr.C088377. Epub 2018 Jul 9. No abstract available.

9.

Investigation of ciguatoxins in invasive lionfish from the greater caribbean region: Implications for fishery development.

Hardison DR, Holland WC, Darius HT, Chinain M, Tester PA, Shea D, Bogdanoff AK, Morris JA Jr, Flores Quintana HA, Loeffler CR, Buddo D, Litaker RW.

PLoS One. 2018 Jun 20;13(6):e0198358. doi: 10.1371/journal.pone.0198358. eCollection 2018.

10.

Publisher Correction: Targeting hepatic glutaminase activity to ameliorate hyperglycemia.

Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ.

Nat Med. 2018 Sep;24(9):1482. doi: 10.1038/s41591-018-0047-1.

PMID:
29895835
11.

Does This Schlank Make Me Look Fat?

Chaurasia B, Holland WL, Summers SA.

Trends Endocrinol Metab. 2018 Sep;29(9):597-599. doi: 10.1016/j.tem.2018.04.003. Epub 2018 Apr 21.

12.

Targeting hepatic glutaminase activity to ameliorate hyperglycemia.

Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ.

Nat Med. 2018 May;24(4):518-524. doi: 10.1038/nm.4514. Epub 2018 Mar 26. Erratum in: Nat Med. 2018 Jun 12;:.

13.

POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels.

Caron A, Dungan Lemko HM, Castorena CM, Fujikawa T, Lee S, Lord CC, Ahmed N, Lee CE, Holland WL, Liu C, Elmquist JK.

Elife. 2018 Mar 12;7. pii: e33710. doi: 10.7554/eLife.33710.

14.

De novo adipocyte differentiation from Pdgfrβ+ preadipocytes protects against pathologic visceral adipose expansion in obesity.

Shao M, Vishvanath L, Busbuso NC, Hepler C, Shan B, Sharma AX, Chen S, Yu X, An YA, Zhu Y, Holland WL, Gupta RK.

Nat Commun. 2018 Mar 1;9(1):890. doi: 10.1038/s41467-018-03196-x.

15.

Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity.

Ye R, Gordillo R, Shao M, Onodera T, Chen Z, Chen S, Lin X, SoRelle JA, Li X, Tang M, Keller MP, Kuliawat R, Attie AD, Gupta RK, Holland WL, Beutler B, Herz J, Scherer PE.

J Clin Invest. 2018 Mar 1;128(3):1178-1189. doi: 10.1172/JCI97702. Epub 2018 Feb 19.

16.

Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice.

Sharma AX, Quittner-Strom EB, Lee Y, Johnson JA, Martin SA, Yu X, Li J, Lu J, Cai Z, Chen S, Wang MY, Zhang Y, Pearson MJ, Dorn AC, McDonald JG, Gordillo R, Yan H, Thai D, Wang ZV, Unger RH, Holland WL.

Cell Rep. 2018 Feb 13;22(7):1760-1773. doi: 10.1016/j.celrep.2018.01.065.

17.

Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice.

Xia JY, Sun K, Hepler C, Ghaben AL, Gupta RK, An YA, Holland WL, Morley TS, Adams AC, Gordillo R, Kusminski CM, Scherer PE.

Diabetologia. 2018 Apr;61(4):932-941. doi: 10.1007/s00125-017-4516-8. Epub 2017 Dec 9.

18.

Hyposialylated IgG activates endothelial IgG receptor FcγRIIB to promote obesity-induced insulin resistance.

Tanigaki K, Sacharidou A, Peng J, Chambliss KL, Yuhanna IS, Ghosh D, Ahmed M, Szalai AJ, Vongpatanasin W, Mattrey RF, Chen Q, Azadi P, Lingvay I, Botto M, Holland WL, Kohler JJ, Sirsi SR, Hoyt K, Shaul PW, Mineo C.

J Clin Invest. 2018 Jan 2;128(1):309-322. doi: 10.1172/JCI89333. Epub 2017 Nov 27.

19.

The flip-flop fungus sign: an FDG PET/CT sign of benignity.

Nagelschneider AA, Broski SM, Holland WP, Midthun DE, Sykes AM, Lowe VJ, Peller PJ, Johnson GB.

Am J Nucl Med Mol Imaging. 2017 Nov 1;7(5):212-217. eCollection 2017.

20.

Ciguatoxicity of Gambierdiscus and Fukuyoa species from the Caribbean and Gulf of Mexico.

Litaker RW, Holland WC, Hardison DR, Pisapia F, Hess P, Kibler SR, Tester PA.

PLoS One. 2017 Oct 18;12(10):e0185776. doi: 10.1371/journal.pone.0185776. eCollection 2017.

21.

Celebrating 30 years of science from the James Clerk Maxwell Telescope.

Robson I, Holland WS, Friberg P.

R Soc Open Sci. 2017 Sep 6;4(9):170754. doi: 10.1098/rsos.170754. eCollection 2017 Sep. Review.

22.

FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia.

Lan T, Morgan DA, Rahmouni K, Sonoda J, Fu X, Burgess SC, Holland WL, Kliewer SA, Mangelsdorf DJ.

Cell Metab. 2017 Nov 7;26(5):709-718.e3. doi: 10.1016/j.cmet.2017.09.005. Epub 2017 Oct 5.

23.

PPARα agonist fenofibrate enhances fatty acid β-oxidation and attenuates polycystic kidney and liver disease in mice.

Lakhia R, Yheskel M, Flaten A, Quittner-Strom EB, Holland WL, Patel V.

Am J Physiol Renal Physiol. 2018 Jan 1;314(1):F122-F131. doi: 10.1152/ajprenal.00352.2017. Epub 2017 Sep 13.

24.

Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses.

Wende AR, Kim J, Holland WL, Wayment BE, O'Neill BT, Tuinei J, Brahma MK, Pepin ME, McCrory MA, Luptak I, Halade GV, Litwin SE, Abel ED.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1098-H1108. doi: 10.1152/ajpheart.00101.2017. Epub 2017 Aug 19.

25.

Adiponectin and its Hydrolase-Activated Receptors.

Sharma AX, Holland WL.

J Nat Sci. 2017 Jun;3(6). pii: e396.

26.

Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice.

Hepler C, Shao M, Xia JY, Ghaben AL, Pearson MJ, Vishvanath L, Sharma AX, Morley TS, Holland WL, Gupta RK.

Elife. 2017 Jul 19;6. pii: e27669. doi: 10.7554/eLife.27669.

27.

Maitotoxin-4, a Novel MTX Analog Produced by Gambierdiscus excentricus.

Pisapia F, Sibat M, Herrenknecht C, Lhaute K, Gaiani G, Ferron PJ, Fessard V, Fraga S, Nascimento SM, Litaker RW, Holland WC, Roullier C, Hess P.

Mar Drugs. 2017 Jul 11;15(7). pii: E220. doi: 10.3390/md15070220.

28.

Dapagliflozin suppresses glucagon signaling in rodent models of diabetes.

Wang MY, Yu X, Lee Y, McCorkle SK, Chen S, Li J, Wang ZV, Davidson JA, Scherer PE, Holland WL, Unger RH, Roth MG.

Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):6611-6616. doi: 10.1073/pnas.1705845114. Epub 2017 Jun 5.

29.

Management of Multifocal Lung Cancer: Results of a Survey.

Leventakos K, Peikert T, Midthun DE, Molina JR, Blackmon S, Nichols FC, Garces YI, Hallemeier CL, Murphy SJ, Vasmatzis G, Kratz SL, Holland WP, Thomas CF, Mullon JJ, Shen KR, Cassivi SD, Marks RS, Aubry MC, Adjei AA, Yang P, Allen MS, Edell ES, Wigle D, Mansfield AS.

J Thorac Oncol. 2017 Sep;12(9):1398-1402. doi: 10.1016/j.jtho.2017.05.013. Epub 2017 Jun 3.

30.

High-Mobility Group Box 1 Disrupts Metabolic Function with Cigarette Smoke Exposure in a Ceramide-Dependent Manner.

Taylor OJ, Thatcher MO, Carr ST, Gibbs JL, Trumbull AM, Harrison ME, Winden DR, Pearson MJ, Tippetts TS, Holland WL, Reynolds PR, Bikman BT.

Int J Mol Sci. 2017 May 20;18(5). pii: E1099. doi: 10.3390/ijms18051099.

31.

Professor Basil S Hetzel, AC, MD, FRACP, FRCP, FFPH.

Holland WW, Southby RF.

Int J Epidemiol. 2017 May 6. doi: 10.1093/ije/dyx077. [Epub ahead of print] No abstract available.

PMID:
28482096
32.

Toxicity screening of 13 Gambierdiscus strains using neuro-2a and erythrocyte lysis bioassays.

Pisapia F, Holland WC, Hardison DR, Litaker RW, Fraga S, Nishimura T, Adachi M, Nguyen-Ngoc L, Séchet V, Amzil Z, Herrenknecht C, Hess P.

Harmful Algae. 2017 Mar;63:173-183. doi: 10.1016/j.hal.2017.02.005. Epub 2017 Mar 9.

PMID:
28366392
33.

Structural biology: Receptors grease the metabolic wheels.

Holland WL, Scherer PE.

Nature. 2017 Apr 6;544(7648):42-44. doi: 10.1038/nature21900. Epub 2017 Mar 22. No abstract available.

PMID:
28329767
34.

Short-Term Versus Long-Term Effects of Adipocyte Toll-Like Receptor 4 Activation on Insulin Resistance in Male Mice.

Tao C, Holland WL, Wang QA, Shao M, Jia L, Sun K, Lin X, Kuo YC, Johnson JA, Gordillo R, Elmquist JK, Scherer PE.

Endocrinology. 2017 May 1;158(5):1260-1270. doi: 10.1210/en.2017-00024.

35.

Insulin and Glucagon: Partners for Life.

Holst JJ, Holland W, Gromada J, Lee Y, Unger RH, Yan H, Sloop KW, Kieffer TJ, Damond N, Herrera PL.

Endocrinology. 2017 Apr 1;158(4):696-701. doi: 10.1210/en.2016-1748. Review.

36.

Glucagon antagonism in islet cell proliferation.

Dean ED, Unger RH, Holland WL.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3006-3008. doi: 10.1073/pnas.1700468114. Epub 2017 Mar 10. No abstract available.

37.

Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis.

Holland WL, Xia JY, Johnson JA, Sun K, Pearson MJ, Sharma AX, Quittner-Strom E, Tippetts TS, Gordillo R, Scherer PE.

Mol Metab. 2017 Jan 12;6(3):267-275. doi: 10.1016/j.molmet.2017.01.002. eCollection 2017 Mar.

38.

microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.

Hajarnis S, Lakhia R, Yheskel M, Williams D, Sorourian M, Liu X, Aboudehen K, Zhang S, Kersjes K, Galasso R, Li J, Kaimal V, Lockton S, Davis S, Flaten A, Johnson JA, Holland WL, Kusminski CM, Scherer PE, Harris PC, Trudel M, Wallace DP, Igarashi P, Lee EC, Androsavich JR, Patel V.

Nat Commun. 2017 Feb 16;8:14395. doi: 10.1038/ncomms14395.

39.

New scenario for speciation in the benthic dinoflagellate genus Coolia (Dinophyceae).

Leaw CP, Tan TH, Lim HC, Teng ST, Yong HL, Smith KF, Rhodes L, Wolf M, Holland WC, Vandersea MW, Litaker RW, Tester PA, Gu H, Usup G, Lim PT.

Harmful Algae. 2016 May;55:137-149. doi: 10.1016/j.hal.2016.02.010. Epub 2016 Mar 15.

PMID:
28073527
40.

Preclinical Evaluation of MET Inhibitor INC-280 With or Without the Epidermal Growth Factor Receptor Inhibitor Erlotinib in Non-Small-Cell Lung Cancer.

Lara MS, Holland WS, Chinn D, Burich RA, Lara PN Jr, Gandara DR, Kelly K, Mack PC.

Clin Lung Cancer. 2017 May;18(3):281-285. doi: 10.1016/j.cllc.2016.11.006. Epub 2016 Nov 21.

41.

αSMA Expression in Large Colonies of Colony-Forming Units-Fibroblast as an Early Predictor of Bone Marrow MSC Expandability.

Aizman I, Holland WS, Yang C, Bates D.

Cell Med. 2016 Oct 6;8(3):79-85. doi: 10.3727/215517916X693357. eCollection 2016 Dec 3.

42.

SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise.

Fujikawa T, Castorena CM, Pearson M, Kusminski CM, Ahmed N, Battiprolu PK, Kim KW, Lee S, Hill JA, Scherer PE, Holland WL, Elmquist JK.

Elife. 2016 Nov 22;5. pii: e18206. doi: 10.7554/eLife.18206.

43.

Willingness and Ability of Older Adults in the Emergency Department to Provide Clinical Information Using a Tablet Computer.

Brahmandam S, Holland WC, Mangipudi SA, Braz VA, Medlin RP, Hunold KM, Jones CW, Platts-Mills TF.

J Am Geriatr Soc. 2016 Nov;64(11):2362-2367. doi: 10.1111/jgs.14366. Epub 2016 Nov 2.

44.

Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals.

Zhu Y, Gao Y, Tao C, Shao M, Zhao S, Huang W, Yao T, Johnson JA, Liu T, Cypess AM, Gupta O, Holland WL, Gupta RK, Spray DC, Tanowitz HB, Cao L, Lynes MD, Tseng YH, Elmquist JK, Williams KW, Lin HV, Scherer PE.

Cell Metab. 2016 Sep 13;24(3):420-433. doi: 10.1016/j.cmet.2016.08.005.

45.

Rapid Extraction and Identification of Maitotoxin and Ciguatoxin-Like Toxins from Caribbean and Pacific Gambierdiscus Using a New Functional Bioassay.

Lewis RJ, Inserra M, Vetter I, Holland WC, Hardison DR, Tester PA, Litaker RW.

PLoS One. 2016 Jul 28;11(7):e0160006. doi: 10.1371/journal.pone.0160006. eCollection 2016.

46.

Clinical Trials, Triumphs, and Tribulations of Glucagon Receptor Antagonists.

Pearson MJ, Unger RH, Holland WL.

Diabetes Care. 2016 Jul;39(7):1075-7. doi: 10.2337/dci15-0033. No abstract available.

47.

Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis.

Ding Y, Xian X, Holland WL, Tsai S, Herz J.

EBioMedicine. 2016 May;7:135-45. doi: 10.1016/j.ebiom.2016.04.002. Epub 2016 Apr 4.

48.

Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program.

Shao M, Ishibashi J, Kusminski CM, Wang QA, Hepler C, Vishvanath L, MacPherson KA, Spurgin SB, Sun K, Holland WL, Seale P, Gupta RK.

Cell Metab. 2016 Jun 14;23(6):1167-1184. doi: 10.1016/j.cmet.2016.04.023. Epub 2016 May 26.

49.

Fluorescent Receptor Binding Assay for Detecting Ciguatoxins in Fish.

Hardison DR, Holland WC, McCall JR, Bourdelais AJ, Baden DG, Darius HT, Chinain M, Tester PA, Shea D, Quintana HA, Morris JA Jr, Litaker RW.

PLoS One. 2016 Apr 13;11(4):e0153348. doi: 10.1371/journal.pone.0153348. eCollection 2016.

50.

A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism.

Amoasii L, Holland W, Sanchez-Ortiz E, Baskin KK, Pearson M, Burgess SC, Nelson BR, Bassel-Duby R, Olson EN.

Genes Dev. 2016 Feb 15;30(4):434-46. doi: 10.1101/gad.273128.115.

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