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Items: 32

1.

Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical.

Kumari V, Dyba MA, Holland RJ, Liang YH, Singh SV, Ji X.

PLoS One. 2016 Sep 29;11(9):e0163821. doi: 10.1371/journal.pone.0163821. eCollection 2016.

2.

PABA/NO lead optimization: Improved targeting of cytotoxicity to glutathione S-transferase P1-overexpressing cancer cells.

Kim Y, Maciag AE, Cao Z, Deschamps JR, Saavedra JE, Keefer LK, Holland RJ.

Bioorg Med Chem. 2015 Aug 1;23(15):4980-8. doi: 10.1016/j.bmc.2015.05.020. Epub 2015 May 19.

PMID:
26043946
3.

Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics.

Kus K, Walczak M, Maslak E, Zakrzewska A, Gonciarz-Dytman A, Zabielski P, Sitek B, Wandzel K, Kij A, Chabowski A, Holland RJ, Saavedra JE, Keefer LK, Chlopicki S.

Drug Metab Dispos. 2015 Jul;43(7):1028-36. doi: 10.1124/dmd.115.063388. Epub 2015 Apr 13.

PMID:
25870102
4.

The liver-selective NO donor, V-PYRRO/NO, protects against liver steatosis and improves postprandial glucose tolerance in mice fed high fat diet.

Maslak E, Zabielski P, Kochan K, Kus K, Jasztal A, Sitek B, Proniewski B, Wojcik T, Gula K, Kij A, Walczak M, Baranska M, Chabowski A, Holland RJ, Saavedra JE, Keefer LK, Chlopicki S.

Biochem Pharmacol. 2015 Feb 1;93(3):389-400. doi: 10.1016/j.bcp.2014.12.004. Epub 2014 Dec 19.

PMID:
25534988
5.

Direct reaction of amides with nitric oxide to form diazeniumdiolates.

Holland RJ, Klose JR, Deschamps JR, Cao Z, Keefer LK, Saavedra JE.

J Org Chem. 2014 Oct 3;79(19):9389-93. doi: 10.1021/jo501670e. Epub 2014 Sep 22.

6.

Aminolysis of an N-diazeniumdiolated amidine as an approach to diazeniumdiolated ammonia.

Biswas D, Hrabie JA, Saavedra JE, Cao Z, Keefer LK, Ivanic J, Holland RJ.

J Org Chem. 2014 May 16;79(10):4512-6. doi: 10.1021/jo500551n. Epub 2014 May 5.

7.

Nitric oxide (NO) releasing poly ADP-ribose polymerase 1 (PARP-1) inhibitors targeted to glutathione S-transferase P1-overexpressing cancer cells.

Maciag AE, Holland RJ, Kim Y, Kumari V, Luthers CE, Sehareen WS, Biswas D, Morris NL, Ji X, Anderson LM, Saavedra JE, Keefer LK.

J Med Chem. 2014 Mar 27;57(6):2292-302. doi: 10.1021/jm401550d. Epub 2014 Feb 25.

8.

Mechanism of action for the cytotoxic effects of the nitric oxide prodrug JS-K in murine erythroleukemia cells.

Kaczmarek MZ, Holland RJ, Lavanier SA, Troxler JA, Fesenkova VI, Hanson CA, Cmarik JL, Saavedra JE, Keefer LK, Ruscetti SK.

Leuk Res. 2014 Mar;38(3):377-82. doi: 10.1016/j.leukres.2013.12.002. Epub 2013 Dec 12.

9.

Enzymatic generation of the NO/HNO-releasing IPA/NO anion at controlled rates in physiological media using β-galactosidase.

Holland RJ, Paulisch R, Cao Z, Keefer LK, Saavedra JE, Donzelli S.

Nitric Oxide. 2013 Nov 30;35:131-6. doi: 10.1016/j.niox.2013.10.003. Epub 2013 Oct 11.

10.

Synthesis and chemical and biological comparison of nitroxyl- and nitric oxide-releasing diazeniumdiolate-based aspirin derivatives.

Basudhar D, Bharadwaj G, Cheng RY, Jain S, Shi S, Heinecke JL, Holland RJ, Ridnour LA, Caceres VM, Spadari-Bratfisch RC, Paolocci N, Velázquez-Martínez CA, Wink DA, Miranda KM.

J Med Chem. 2013 Oct 24;56(20):7804-20. doi: 10.1021/jm400196q. Epub 2013 Oct 8.

11.

Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance.

Maciag AE, Holland RJ, Robert Cheng YS, Rodriguez LG, Saavedra JE, Anderson LM, Keefer LK.

Redox Biol. 2013 Feb 1;1:115-24. doi: 10.1016/j.redox.2012.12.002. eCollection 2013.

12.

Decoding nitric oxide release rates of amine-based diazeniumdiolates.

Wang YN, Collins J, Holland RJ, Keefer LK, Ivanic J.

J Phys Chem A. 2013 Aug 1;117(30):6671-7. doi: 10.1021/jp404589p. Epub 2013 Jul 23.

13.

Elemental composition of natural populations of key microbial groups in Atlantic waters.

Grob C, Ostrowski M, Holland RJ, Heldal M, Norland S, Erichsen ES, Blindauer C, Martin AP, Zubkov MV, Scanlan DJ.

Environ Microbiol. 2013 Nov;15(11):3054-64. doi: 10.1111/1462-2920.12145. Epub 2013 May 13.

PMID:
23663455
14.

O2-functionalized methylamine diazeniumdiolates: evidence for E ⇄ Z equilibration in an acyclic system.

Biswas D, Holland RJ, Deschamps JR, Cao Z, Keefer LK, Saavedra JE.

J Org Chem. 2012 Dec 7;77(23):10804-10. doi: 10.1021/jo3020837. Epub 2012 Nov 20.

PMID:
23137026
15.

Cross-linking protein glutathionylation mediated by O2-arylated bis-diazeniumdiolate "Double JS-K".

Holland RJ, Maciag AE, Kumar V, Shi L, Saavedra JE, Prud'homme RK, Chakrapani H, Keefer LK.

Chem Res Toxicol. 2012 Dec 17;25(12):2670-7. doi: 10.1021/tx3003142. Epub 2012 Nov 9.

16.

Structural modifications modulate stability of glutathione-activated arylated diazeniumdiolate prodrugs.

Nandurdikar RS, Maciag AE, Holland RJ, Cao Z, Shami PJ, Anderson LM, Keefer LK, Saavedra JE.

Bioorg Med Chem. 2012 May 1;20(9):3094-9. doi: 10.1016/j.bmc.2012.02.045. Epub 2012 Mar 9.

17.

Thiol Modification By Pharmacologically Active Agents of the Diazeniumdiolate Class.

Maciag AE, Holland RJ, Saavedra JE, Chakrapani H, Shami PJ, Keefer LK.

For Immunopathol Dis Therap. 2012;3(2):91-95.

18.

Internal and external influences on near-surface microbial community structure in the vicinity of the Cape Verde Islands.

Hill PG, Heywood JL, Holland RJ, Purdie DA, Fuchs BM, Zubkov MV.

Microb Ecol. 2012 Jan;63(1):139-48. doi: 10.1007/s00248-011-9952-2. Epub 2011 Oct 13.

PMID:
21994033
19.

The nitric oxide prodrug JS-K is effective against non-small-cell lung cancer cells in vitro and in vivo: involvement of reactive oxygen species.

Maciag AE, Chakrapani H, Saavedra JE, Morris NL, Holland RJ, Kosak KM, Shami PJ, Anderson LM, Keefer LK.

J Pharmacol Exp Ther. 2011 Feb;336(2):313-20. doi: 10.1124/jpet.110.174904. Epub 2010 Oct 20.

20.

"Click" reaction in conjunction with diazeniumdiolate chemistry: developing high-load nitric oxide donors.

Oladeinde OA, Hong SY, Holland RJ, Maciag AE, Keefer LK, Saavedra JE, Nandurdikar RS.

Org Lett. 2010 Oct 1;12(19):4256-9. doi: 10.1021/ol101645k.

21.

Southern Ocean deep-water carbon export enhanced by natural iron fertilization.

Pollard RT, Salter I, Sanders RJ, Lucas MI, Moore CM, Mills RA, Statham PJ, Allen JT, Baker AR, Bakker DC, Charette MA, Fielding S, Fones GR, French M, Hickman AE, Holland RJ, Hughes JA, Jickells TD, Lampitt RS, Morris PJ, Nédélec FH, Nielsdóttir M, Planquette H, Popova EE, Poulton AJ, Read JF, Seeyave S, Smith T, Stinchcombe M, Taylor S, Thomalla S, Venables HJ, Williamson R, Zubkov MV.

Nature. 2009 Jan 29;457(7229):577-80. doi: 10.1038/nature07716.

PMID:
19177128
22.

Extreme spatial variability in marine picoplankton and its consequences for interpreting Eulerian time-series.

Martin AP, Zubkov MV, Burkill PH, Holland RJ.

Biol Lett. 2005 Sep 22;1(3):366-9.

23.

Ultrastructure and properties of Paecilomyces lilacinus spores.

Holland RJ, Gunasekera TS, Williams KL, Nevalainen KM.

Can J Microbiol. 2002 Oct;48(10):879-85.

PMID:
12489777
24.

Can a single individualized procedure predictably resolve all the problematic aspects of the pediatric ureterocele?

Decter RM, Sprunger JK, Holland RJ.

J Urol. 2001 Jun;165(6 Pt 2):2308-10.

PMID:
11371968
25.

Phenotypic and genetic characterization of Paecilomyces lilacinus strains with biocontrol activity against root-knot nematodes.

Gunasekera TS, Holland RJ, Gillings MR, Briscoe DA, Neethling DC, Williams KL, Nevalainen KM.

Can J Microbiol. 2000 Sep;46(9):775-83.

PMID:
11006837
26.

Epizootic of Yersinia pseudotuberculosis in a wildlife park.

Welsh RD, Ely RW, Holland RJ.

J Am Vet Med Assoc. 1992 Jul 1;201(1):142-4.

PMID:
1644638
27.

Cryptofluorescent analogs of cobalamin coenzymes: synthesis and characterization.

Jacobsen DW, Holland RJ, Montejano Y, Huennekens FM.

J Inorg Biochem. 1979 Feb;10(1):53-65.

PMID:
448353
28.

Methylcobalamin and methylcobalt complexes of vitamin B12 model compounds as substrates in nucleophilic displacement reactions.

Stadlbauer EA, Holland RJ, Lamm FP, Schrauzer GN.

Bioinorg Chem. 1974 Oct;4(1):67-77. No abstract available.

PMID:
4433639
29.

Concerning the mechanism of action of coenzyme B 12 in dioldehydrase and related enzymes. Synthesis and reactions of postulated organocorrin intermediates.

Schrauzer GN, Michaely WJ, Holland RJ.

J Am Chem Soc. 1973 Mar 21;95(6):2024-6. No abstract available.

PMID:
4689926
30.

Hydridocobalamin and a new synthesis of organocobalt derivatives of vitamin B 12 .

Schrauzer GN, Holland RJ.

J Am Chem Soc. 1971 Aug 11;93(16):4060-2. No abstract available.

PMID:
5138307
31.

Transformation of polarization form to allow accurate intensity measurements with polarization sensitive instruments.

Kay RB, Holland RJ.

Appl Opt. 1971 Jul 1;10(7):1587-90. doi: 10.1364/AO.10.001587.

PMID:
20111167
32.

The mechanism of coenzyme B12 action in dioldehydrase.

Schrauzer GN, Holland RJ, Seck JA.

J Am Chem Soc. 1971 Mar 24;93(6):1503-5. No abstract available.

PMID:
5548349

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