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Items: 18

1.

Mapping Citrullinated Sites in Multiple Organs of Mice Using Hypercitrullinated Library.

Fert-Bober J, Venkatraman V, Hunter CL, Liu R, Crowgey EL, Pandey R, Holewinski RJ, Stotland A, Berman BP, Van Eyk JE.

J Proteome Res. 2019 May 3;18(5):2270-2278. doi: 10.1021/acs.jproteome.9b00118. Epub 2019 Apr 23.

PMID:
30990720
2.

PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress.

Ranek MJ, Kokkonen-Simon KM, Chen A, Dunkerly-Eyring BL, Vera MP, Oeing CU, Patel CH, Nakamura T, Zhu G, Bedja D, Sasaki M, Holewinski RJ, Van Eyk JE, Powell JD, Lee DI, Kass DA.

Nature. 2019 Feb;566(7743):264-269. doi: 10.1038/s41586-019-0895-y. Epub 2019 Jan 30.

3.

Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function.

Papadaki M, Holewinski RJ, Previs SB, Martin TG, Stachowski MJ, Li A, Blair CA, Moravec CS, Van Eyk JE, Campbell KS, Warshaw DM, Kirk JA.

JCI Insight. 2018 Oct 18;3(20). pii: 121264. doi: 10.1172/jci.insight.121264.

4.

Phospho-Proteomic Analysis of Cardiac Dyssynchrony and Resynchronization Therapy.

Stachowski MJ, Holewinski RJ, Grote E, Venkatraman V, Van Eyk JE, Kirk JA.

Proteomics. 2018 Oct;18(19):e1800079. doi: 10.1002/pmic.201800079. Epub 2018 Aug 30.

PMID:
30129105
5.

Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure.

Rainer PP, Dong P, Sorge M, Fert-Bober J, Holewinski RJ, Wang Y, Foss CA, An SS, Baracca A, Solaini G, Glabe CG, Pomper MG, Van Eyk JE, Tomaselli GF, Paolocci N, Agnetti G.

Circ Res. 2018 May 11;122(10):e75-e83. doi: 10.1161/CIRCRESAHA.117.312082. Epub 2018 Feb 26.

6.

Transient receptor potential channel 6 regulates abnormal cardiac S-nitrosylation in Duchenne muscular dystrophy.

Chung HS, Kim GE, Holewinski RJ, Venkatraman V, Zhu G, Bedja D, Kass DA, Van Eyk JE.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10763-E10771. doi: 10.1073/pnas.1712623114. Epub 2017 Nov 29.

7.

Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1.

Bullen JW, Tchernyshyov I, Holewinski RJ, DeVine L, Wu F, Venkatraman V, Kass DL, Cole RN, Van Eyk J, Semenza GL.

Sci Signal. 2016 May 31;9(430):ra56. doi: 10.1126/scisignal.aaf0583.

8.

Methods for SWATH™: Data Independent Acquisition on TripleTOF Mass Spectrometers.

Holewinski RJ, Parker SJ, Matlock AD, Venkatraman V, Van Eyk JE.

Methods Mol Biol. 2016;1410:265-79. doi: 10.1007/978-1-4939-3524-6_16.

PMID:
26867750
9.

Pacemaker-induced transient asynchrony suppresses heart failure progression.

Kirk JA, Chakir K, Lee KH, Karst E, Holewinski RJ, Pironti G, Tunin RS, Pozios I, Abraham TP, de Tombe P, Rockman HA, Van Eyk JE, Craig R, Farazi TG, Kass DA.

Sci Transl Med. 2015 Dec 23;7(319):319ra207. doi: 10.1126/scitranslmed.aad2899.

10.

Protein kinase G signaling in cardiac pathophysiology: Impact of proteomics on clinical trials.

Kirk JA, Holewinski RJ, Crowgey EL, Van Eyk JE.

Proteomics. 2016 Mar;16(5):894-905. doi: 10.1002/pmic.201500401. Epub 2016 Feb 16. Review.

PMID:
26670943
11.

A novel phosphorylation site at Ser130 adjacent to the pseudosubstrate domain contributes to the activation of protein kinase C-δ.

Gong J, Holewinski RJ, Van Eyk JE, Steinberg SF.

Biochem J. 2016 Feb 1;473(3):311-20. doi: 10.1042/BJ20150812. Epub 2015 Nov 6.

12.

Citrullination of myofilament proteins in heart failure.

Fert-Bober J, Giles JT, Holewinski RJ, Kirk JA, Uhrigshardt H, Crowgey EL, Andrade F, Bingham CO 3rd, Park JK, Halushka MK, Kass DA, Bathon JM, Van Eyk JE.

Cardiovasc Res. 2015 Nov 1;108(2):232-42. doi: 10.1093/cvr/cvv185. Epub 2015 Jun 25.

13.

Inhibition by active site directed covalent modification of human glyoxalase I.

Holewinski RJ, Creighton DJ.

Bioorg Med Chem. 2014 Jul 1;22(13):3301-8. doi: 10.1016/j.bmc.2014.04.055. Epub 2014 May 6.

14.

Cardiac resynchronization sensitizes the sarcomere to calcium by reactivating GSK-3β.

Kirk JA, Holewinski RJ, Kooij V, Agnetti G, Tunin RS, Witayavanitkul N, de Tombe PP, Gao WD, Van Eyk J, Kass DA.

J Clin Invest. 2014 Jan;124(1):129-38.

15.

Characterization of the cardiac myosin binding protein-C phosphoproteome in healthy and failing human hearts.

Kooij V, Holewinski RJ, Murphy AM, Van Eyk JE.

J Mol Cell Cardiol. 2013 Jul;60:116-20. doi: 10.1016/j.yjmcc.2013.04.012. Epub 2013 Apr 22.

16.

A fast and reproducible method for albumin isolation and depletion from serum and cerebrospinal fluid.

Holewinski RJ, Jin Z, Powell MJ, Maust MD, Van Eyk JE.

Proteomics. 2013 Mar;13(5):743-50. doi: 10.1002/pmic.201200192. Epub 2013 Jan 29.

17.

Dephosphorylation of cardiac proteins in vitro - a matter of phosphatase specificity.

Husberg C, Agnetti G, Holewinski RJ, Christensen G, Van Eyk JE.

Proteomics. 2012 Apr;12(7):973-8. doi: 10.1002/pmic.201100116.

18.

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