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Items: 18


WormCat: An Online Tool for Annotation and Visualization of Caenorhabditis elegans Genome-Scale Data.

Holdorf AD, Higgins DP, Hart AC, Boag PR, Pazour GJ, Walhout AJM, Walker AK.

Genetics. 2020 Feb;214(2):279-294. doi: 10.1534/genetics.119.302919. Epub 2019 Dec 6.


A Delicate Balance between Bacterial Iron and Reactive Oxygen Species Supports Optimal C. elegans Development.

Zhang J, Li X, Olmedo M, Holdorf AD, Shang Y, Artal-Sanz M, Yilmaz LS, Walhout AJM.

Cell Host Microbe. 2019 Sep 11;26(3):400-411.e3. doi: 10.1016/j.chom.2019.07.010. Epub 2019 Aug 20.


A Persistence Detector for Metabolic Network Rewiring in an Animal.

Bulcha JT, Giese GE, Ali MZ, Lee YU, Walker MD, Holdorf AD, Yilmaz LS, Brewster RC, Walhout AJM.

Cell Rep. 2019 Jan 8;26(2):460-468.e4. doi: 10.1016/j.celrep.2018.12.064.


Many transcription factors contribute to C. elegans growth and fat storage.

Mori A, Holdorf AD, Walhout AJM.

Genes Cells. 2017 Sep;22(9):770-784. doi: 10.1111/gtc.12516. Epub 2017 Aug 8.


PRIMA: a gene-centered, RNA-to-protein method for mapping RNA-protein interactions.

Tamburino AM, Kaymak E, Shrestha S, Holdorf AD, Ryder SP, Walhout AJM.

Translation (Austin). 2017 Feb 28;5(1):e1295130. doi: 10.1080/21690731.2017.1295130. eCollection 2017.


C. elegans and its bacterial diet as a model for systems-level understanding of host-microbiota interactions.

Zhang J, Holdorf AD, Walhout AJ.

Curr Opin Biotechnol. 2017 Aug;46:74-80. doi: 10.1016/j.copbio.2017.01.008. Epub 2017 Feb 9. Review.


A gene-centered C. elegans protein-DNA interaction network provides a framework for functional predictions.

Fuxman Bass JI, Pons C, Kozlowski L, Reece-Hoyes JS, Shrestha S, Holdorf AD, Mori A, Myers CL, Walhout AJ.

Mol Syst Biol. 2016 Oct 24;12(10):884. doi: 10.15252/msb.20167131.


Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans.

Watson E, Olin-Sandoval V, Hoy MJ, Li CH, Louisse T, Yao V, Mori A, Holdorf AD, Troyanskaya OG, Ralser M, Walhout AJ.

Elife. 2016 Jul 6;5. pii: e17670. doi: 10.7554/eLife.17670.


AVX-470: a novel oral anti-TNF antibody with therapeutic potential in inflammatory bowel disease.

Bhol KC, Tracey DE, Lemos BR, Lyng GD, Erlich EC, Keane DM, Quesenberry MS, Holdorf AD, Schlehuber LD, Clark SA, Fox BS.

Inflamm Bowel Dis. 2013 Oct;19(11):2273-81. doi: 10.1097/MIB.0b013e3182a11958.


Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire.

Roy E, Togbe D, Holdorf AD, Trubetskoy D, Nabti S, Küblbeck G, Klevenz A, Kopp-Schneider A, Leithäuser F, Möller P, Bladt F, Hämmerling G, Arnold B, Pawson T, Tafuri A.

Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15529-34. doi: 10.1073/pnas.1009743107. Epub 2010 Aug 13.


A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.

Plant PJ, Fawcett JP, Lin DC, Holdorf AD, Binns K, Kulkarni S, Pawson T.

Nat Cell Biol. 2003 Apr;5(4):301-8.


Cutting edge: quantitative imaging of raft accumulation in the immunological synapse.

Burack WR, Lee KH, Holdorf AD, Dustin ML, Shaw AS.

J Immunol. 2002 Sep 15;169(6):2837-41.


T cell receptor signaling precedes immunological synapse formation.

Lee KH, Holdorf AD, Dustin ML, Chan AC, Allen PM, Shaw AS.

Science. 2002 Feb 22;295(5559):1539-42.


Regulation of Lck activity by CD4 and CD28 in the immunological synapse.

Holdorf AD, Lee KH, Burack WR, Allen PM, Shaw AS.

Nat Immunol. 2002 Mar;3(3):259-64. Epub 2002 Feb 4.


CD28 and T cell co-stimulation.

Holdorf AD, Kanagawa O, Shaw AS.

Rev Immunogenet. 2000;2(2):175-84. Review.


CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.

Carey KD, Dillon TJ, Schmitt JM, Baird AM, Holdorf AD, Straus DB, Shaw AS, Stork PJ.

Mol Cell Biol. 2000 Nov;20(22):8409-19.


Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation.

Holdorf AD, Green JM, Levin SD, Denny MF, Straus DB, Link V, Changelian PS, Allen PM, Shaw AS.

J Exp Med. 1999 Aug 2;190(3):375-84.


A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts.

Dustin ML, Olszowy MW, Holdorf AD, Li J, Bromley S, Desai N, Widder P, Rosenberger F, van der Merwe PA, Allen PM, Shaw AS.

Cell. 1998 Sep 4;94(5):667-77.

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