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Items: 10


Genome-wide Estrogen Receptor-α activation is sustained, not cyclical.

Holding AN, Cullen AE, Markowetz F.

Elife. 2018 Nov 20;7. pii: e40854. doi: 10.7554/eLife.40854.


KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice.

Polson ES, Kuchler VB, Abbosh C, Ross EM, Mathew RK, Beard HA, da Silva B, Holding AN, Ballereau S, Chuntharpursat-Bon E, Williams J, Griffiths HBS, Shao H, Patel A, Davies AJ, Droop A, Chumas P, Short SC, Lorger M, Gestwicki JE, Roberts LD, Bon RS, Allison SJ, Zhu S, Markowetz F, Wurdak H.

Sci Transl Med. 2018 Aug 15;10(454). pii: eaar2718. doi: 10.1126/scitranslmed.aar2718.


A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes.

Papachristou EK, Kishore K, Holding AN, Harvey K, Roumeliotis TI, Chilamakuri CSR, Omarjee S, Chia KM, Swarbrick A, Lim E, Markowetz F, Eldridge M, Siersbaek R, D'Santos CS, Carroll JS.

Nat Commun. 2018 Jun 13;9(1):2311. doi: 10.1038/s41467-018-04619-5.


Parallel factor ChIP provides essential internal control for quantitative differential ChIP-seq.

Guertin MJ, Cullen AE, Markowetz F, Holding AN.

Nucleic Acids Res. 2018 Jul 6;46(12):e75. doi: 10.1093/nar/gky252.


XL-MS: Protein cross-linking coupled with mass spectrometry.

Holding AN.

Methods. 2015 Nov 1;89:54-63. doi: 10.1016/j.ymeth.2015.06.010. Epub 2015 Jun 12. Review.


Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking.

Lee J, Ding S, Walpole TB, Holding AN, Montgomery MG, Fearnley IM, Walker JE.

J Biol Chem. 2015 May 22;290(21):13308-20. doi: 10.1074/jbc.M115.645283. Epub 2015 Apr 7.


Hekate: software suite for the mass spectrometric analysis and three-dimensional visualization of cross-linked protein samples.

Holding AN, Lamers MH, Stephens E, Skehel JM.

J Proteome Res. 2013 Dec 6;12(12):5923-33. doi: 10.1021/pr4003867. Epub 2013 Oct 4.


Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein.

Liu Y, Salter HK, Holding AN, Johnson CM, Stephens E, Lukavsky PJ, Walshaw J, Bullock SL.

Genes Dev. 2013 Jun 1;27(11):1233-46. doi: 10.1101/gad.212381.112. Epub 2013 May 30.


Architecture of the Pol III-clamp-exonuclease complex reveals key roles of the exonuclease subunit in processive DNA synthesis and repair.

Toste Rêgo A, Holding AN, Kent H, Lamers MH.

EMBO J. 2013 May 2;32(9):1334-43. doi: 10.1038/emboj.2013.68. Epub 2013 Apr 2.


Investigation into the mechanism of phenolic couplings during the biosynthesis of glycopeptide antibiotics.

Holding AN, Spencer JB.

Chembiochem. 2008 Sep 22;9(14):2209-14. doi: 10.1002/cbic.200800303. No abstract available.


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