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Items: 1 to 50 of 116

1.

The Caenorhabditis elegans cysteine-string protein homologue DNJ-14 is dispensable for neuromuscular junction maintenance across ageing.

Mulcahy B, Ibbett P, Holden-Dye L, O'Connor V.

J Exp Biol. 2019 Nov 25;222(Pt 22). pii: jeb205450. doi: 10.1242/jeb.205450.

PMID:
31624097
2.

Editorial: CephsInAction: Towards Future Challenges for Cephalopod Science.

Holden-Dye L, Ponte G, Allcock AL, Vidal EAG, Nakajima R, Peterson TR, Fiorito G.

Front Physiol. 2019 Jul 25;10:980. doi: 10.3389/fphys.2019.00980. eCollection 2019. No abstract available.

3.

Neuroligin tuning of pharyngeal pumping reveals extrapharyngeal modulation of feeding in Caenorhabditis elegans.

Calahorro F, Keefe F, Dillon J, Holden-Dye L, O'Connor V.

J Exp Biol. 2019 Feb 8;222(Pt 3). pii: jeb189423. doi: 10.1242/jeb.189423.

4.

Yeast two-hybrid screening identifies MPZ-1 and PTP-1 as candidate scaffolding proteins of metabotropic glutamate receptors in Caenorhabditis elegans.

Dillon J, Holden-Dye L, O'Connor V.

Invert Neurosci. 2018 Nov 11;18(4):16. doi: 10.1007/s10158-018-0218-2.

PMID:
30417267
5.

Investigation of feeding behaviour in C. elegans reveals distinct pharmacological and antibacterial effects of nicotine.

Kudelska MM, Lewis A, Ng CT, Doyle DA, Holden-Dye L, O'Connor VM, Walker RJ.

Invert Neurosci. 2018 Nov 7;18(4):14. doi: 10.1007/s10158-018-0219-1.

PMID:
30406344
6.

Deciphering the molecular determinants of cholinergic anthelmintic sensitivity in nematodes: When novel functional validation approaches highlight major differences between the model Caenorhabditis elegans and parasitic species.

Blanchard A, Guégnard F, Charvet CL, Crisford A, Courtot E, Sauvé C, Harmache A, Duguet T, O'Connor V, Castagnone-Sereno P, Reaves B, Wolstenholme AJ, Beech RN, Holden-Dye L, Neveu C.

PLoS Pathog. 2018 May 2;14(5):e1006996. doi: 10.1371/journal.ppat.1006996. eCollection 2018 May.

7.

The long and the short of it - a perspective on peptidergic regulation of circuits and behaviour.

Jékely G, Melzer S, Beets I, Kadow ICG, Koene J, Haddad S, Holden-Dye L.

J Exp Biol. 2018 Feb 8;221(Pt 3). pii: jeb166710. doi: 10.1242/jeb.166710. Review.

8.

Progressive metabolic impairment underlies the novel nematicidal action of fluensulfone on the potato cyst nematode Globodera pallida.

Kearn J, Lilley C, Urwin P, O'Connor V, Holden-Dye L.

Pestic Biochem Physiol. 2017 Oct;142:83-90. doi: 10.1016/j.pestbp.2017.01.009. Epub 2017 Jan 13.

9.

An oxytocin-dependent social interaction between larvae and adult C. elegans.

Scott E, Hudson A, Feist E, Calahorro F, Dillon J, de Freitas R, Wand M, Schoofs L, O'Connor V, Holden-Dye L.

Sci Rep. 2017 Aug 31;7(1):10122. doi: 10.1038/s41598-017-09350-7.

10.

Coherent anti-Stokes Raman scattering (CARS) spectroscopy in Caenorhabditis elegans and Globodera pallida: evidence for an ivermectin-activated decrease in lipid stores.

Smus JP, Ludlow E, Dallière N, Luedtke S, Monfort T, Lilley C, Urwin P, Walker RJ, O'Connor V, Holden-Dye L, Mahajan S.

Pest Manag Sci. 2017 Dec;73(12):2550-2558. doi: 10.1002/ps.4707. Epub 2017 Sep 25.

11.

Concentration-dependent effects of acute and chronic neonicotinoid exposure on the behaviour and development of the nematode Caenorhabditis elegans.

Kudelska MM, Holden-Dye L, O'Connor V, Doyle DA.

Pest Manag Sci. 2017 Jul;73(7):1345-1351. doi: 10.1002/ps.4564. Epub 2017 May 9.

PMID:
28261957
12.

Chemical activation of a food deprivation signal extends lifespan.

Lucanic M, Garrett T, Yu I, Calahorro F, Asadi Shahmirzadi A, Miller A, Gill MS, Hughes RE, Holden-Dye L, Lithgow GJ.

Aging Cell. 2016 Oct;15(5):832-41. doi: 10.1111/acel.12492. Epub 2016 May 24.

13.

Context-dependent regulation of feeding behaviour by the insulin receptor, DAF-2, in Caenorhabditis elegans.

Dillon J, Holden-Dye L, O'Connor V, Hopper NA.

Invert Neurosci. 2016 Jun;16(2):4. doi: 10.1007/s10158-016-0187-2. Epub 2016 May 21.

15.

Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes.

Courtot E, Charvet CL, Beech RN, Harmache A, Wolstenholme AJ, Holden-Dye L, O'Connor V, Peineau N, Woods DJ, Neveu C.

PLoS Pathog. 2015 Dec 1;11(12):e1005267. doi: 10.1371/journal.ppat.1005267. eCollection 2015 Dec.

16.

Multiple excitatory and inhibitory neural signals converge to fine-tune Caenorhabditis elegans feeding to food availability.

Dallière N, Bhatla N, Luedtke Z, Ma DK, Woolman J, Walker RJ, Holden-Dye L, O'Connor V.

FASEB J. 2016 Feb;30(2):836-48. doi: 10.1096/fj.15-279257. Epub 2015 Oct 29.

17.

The Cyclooctadepsipeptide Anthelmintic Emodepside Differentially Modulates Nematode, Insect and Human Calcium-Activated Potassium (SLO) Channel Alpha Subunits.

Crisford A, Ebbinghaus-Kintscher U, Schoenhense E, Harder A, Raming K, O'Kelly I, Ndukwe K, O'Connor V, Walker RJ, Holden-Dye L.

PLoS Negl Trop Dis. 2015 Oct 5;9(10):e0004062. doi: 10.1371/journal.pntd.0004062. eCollection 2015.

18.

Invertebrate neuroscience and CephsInAction at the Mediterranean Society for Neuroscience Meeting Cagliari 2015.

Holden-Dye L, Fiorito G, Ponte G.

Invert Neurosci. 2015 Dec;15(4):6. doi: 10.1007/s10158-015-0182-z.

PMID:
26386979
19.

Metabotropic Glutamate Receptors: MODULATORS OF CONTEXT-DEPENDENT FEEDING BEHAVIOUR IN C. ELEGANS.

Dillon J, Franks CJ, Murray C, Edwards RJ, Calahorro F, Ishihara T, Katsura I, Holden-Dye L, O'Connor V.

J Biol Chem. 2015 Jun 12;290(24):15052-65. doi: 10.1074/jbc.M114.606608. Epub 2015 Apr 13.

20.

Analysis of splice variants for the C. elegans orthologue of human neuroligin reveals a developmentally regulated transcript.

Calahorro F, Holden-Dye L, O'Connor V.

Gene Expr Patterns. 2015 Mar;17(2):69-78. doi: 10.1016/j.gep.2015.02.002. Epub 2015 Feb 26.

PMID:
25726726
21.

Anthelmintic drugs and nematicides: studies in Caenorhabditis elegans.

Holden-Dye L, Walker RJ.

WormBook. 2014 Dec 16:1-29. doi: 10.1895/wormbook.1.143.2. Review.

22.

StyletChip: a microfluidic device for recording host invasion behaviour and feeding of plant parasitic nematodes.

Hu C, Kearn J, Urwin P, Lilley C, O' Connor V, Holden-Dye L, Morgan H.

Lab Chip. 2014 Jul 21;14(14):2447-55. doi: 10.1039/c4lc00292j.

PMID:
24839944
23.

Fluensulfone is a nematicide with a mode of action distinct from anticholinesterases and macrocyclic lactones.

Kearn J, Ludlow E, Dillon J, O'Connor V, Holden-Dye L.

Pestic Biochem Physiol. 2014 Feb;109:44-57. doi: 10.1016/j.pestbp.2014.01.004. Epub 2014 Jan 31.

24.

Distinct molecular targets including SLO-1 and gap junctions are engaged across a continuum of ethanol concentrations in Caenorhabditis elegans.

Dillon J, Andrianakis I, Mould R, Ient B, Liu W, James C, O'Connor V, Holden-Dye L.

FASEB J. 2013 Oct;27(10):4266-78. doi: 10.1096/fj.11-189340. Epub 2013 Jul 23.

25.

NeuroChip: a microfluidic electrophysiological device for genetic and chemical biology screening of Caenorhabditis elegans adult and larvae.

Hu C, Dillon J, Kearn J, Murray C, O'Connor V, Holden-Dye L, Morgan H.

PLoS One. 2013 May 22;8(5):e64297. doi: 10.1371/journal.pone.0064297. Print 2013.

26.

Nicotinic acetylcholine receptors: a comparison of the nAChRs of Caenorhabditis elegans and parasitic nematodes.

Holden-Dye L, Joyner M, O'Connor V, Walker RJ.

Parasitol Int. 2013 Dec;62(6):606-15. doi: 10.1016/j.parint.2013.03.004. Epub 2013 Mar 15. Review.

PMID:
23500392
27.
28.

Polyglutamine aggregate structure in vitro and in vivo; new avenues for coherent anti-Stokes Raman scattering microscopy.

Perney NM, Braddick L, Jurna M, Garbacik ET, Offerhaus HL, Serpell LC, Blanch E, Holden-Dye L, Brocklesby WS, Melvin T.

PLoS One. 2012;7(7):e40536. doi: 10.1371/journal.pone.0040536. Epub 2012 Jul 20.

29.

Anthelmintic cyclcooctadepsipeptides: complex in structure and mode of action.

Krücken J, Harder A, Jeschke P, Holden-Dye L, O'Connor V, Welz C, von Samson-Himmelstjerna G.

Trends Parasitol. 2012 Sep;28(9):385-94. doi: 10.1016/j.pt.2012.06.005. Epub 2012 Jul 31. Review.

PMID:
22858281
30.

HSP-4 endoplasmic reticulum (ER) stress pathway is not activated in a C. elegans model of ethanol intoxication and withdrawal.

Ient B, Edwards R, Mould R, Hannah M, Holden-Dye L, O'Connor V.

Invert Neurosci. 2012 Dec;12(2):93-102. doi: 10.1007/s10158-012-0136-7. Epub 2012 Jun 4.

PMID:
22661239
31.
32.

Worms take to the slo lane: a perspective on the mode of action of emodepside.

Holden-Dye L, Crisford A, Welz C, von Samson-Himmelstjerna G, Walker RJ, O'Connor V.

Invert Neurosci. 2012 Jun;12(1):29-36. doi: 10.1007/s10158-012-0133-x. Epub 2012 Apr 27. Review.

33.
34.

Neurobiology of plant parasitic nematodes.

Holden-Dye L, Walker RJ.

Invert Neurosci. 2011 Jun;11(1):9-19. doi: 10.1007/s10158-011-0117-2. Epub 2011 May 3. Review.

PMID:
21538093
35.

SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants.

Welz C, Krüger N, Schniederjans M, Miltsch SM, Krücken J, Guest M, Holden-Dye L, Harder A, von Samson-Himmelstjerna G.

PLoS Pathog. 2011 Apr;7(4):e1001330. doi: 10.1371/journal.ppat.1001330. Epub 2011 Apr 7.

36.

Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans.

Crisford A, Murray C, O'Connor V, Edwards RJ, Kruger N, Welz C, von Samson-Himmelstjerna G, Harder A, Walker RJ, Holden-Dye L.

Mol Pharmacol. 2011 Jun;79(6):1031-43. doi: 10.1124/mol.111.071043. Epub 2011 Mar 17.

37.

The regulation of feeding and metabolism in response to food deprivation in Caenorhabditis elegans.

Luedtke S, O'Connor V, Holden-Dye L, Walker RJ.

Invert Neurosci. 2010 Dec;10(2):63-76. doi: 10.1007/s10158-010-0112-z. Epub 2010 Dec 1. Review.

PMID:
21120572
38.

The effect of a selective octopamine antagonist, epinastine, on pharyngeal pumping in Caenorhabditis elegans.

Packham R, Walker RJ, Holden-Dye L.

Invert Neurosci. 2010 Nov;10(1):47-52. doi: 10.1007/s10158-010-0107-9. Epub 2010 Oct 22.

PMID:
20967561
39.

Synthesis and properties of triplex-forming oligonucleotides containing 2'-O-(2-methoxyethyl)-5-(3-aminoprop-1-ynyl)-uridine.

Lou C, Xiao Q, Brennan L, Light ME, Vergara-Irigaray N, Atkinson EM, Holden-Dye LM, Fox KR, Brown T.

Bioorg Med Chem. 2010 Sep 1;18(17):6389-97. doi: 10.1016/j.bmc.2010.07.005. Epub 2010 Jul 30.

PMID:
20674370
40.

A differential role for neuropeptides in acute and chronic adaptive responses to alcohol: behavioural and genetic analysis in Caenorhabditis elegans.

Mitchell P, Mould R, Dillon J, Glautier S, Andrianakis I, James C, Pugh A, Holden-Dye L, O'Connor V.

PLoS One. 2010 May 3;5(5):e10422. doi: 10.1371/journal.pone.0010422.

41.

The actions of chloride channel blockers, barbiturates and a benzodiazepine on Caenorhabditis elegans glutamate- and ivermectin-gated chloride channel subunits expressed in Xenopus oocytes.

Bush E, Foreman R, Walker RJ, Holden-Dye L.

Invert Neurosci. 2009 Dec;9(3-4):175-84. doi: 10.1007/s10158-010-0096-8. Epub 2010 Mar 12.

PMID:
20224918
42.

A review of FMRFamide- and RFamide-like peptides in metazoa.

Walker RJ, Papaioannou S, Holden-Dye L.

Invert Neurosci. 2009 Dec;9(3-4):111-53. doi: 10.1007/s10158-010-0097-7. Epub 2010 Feb 26.

PMID:
20191373
43.

AutoEPG: software for the analysis of electrical activity in the microcircuit underpinning feeding behaviour of Caenorhabditis elegans.

Dillon J, Andrianakis I, Bull K, Glautier S, O'Connor V, Holden-Dye L, James C.

PLoS One. 2009 Dec 29;4(12):e8482. doi: 10.1371/journal.pone.0008482.

44.

A comparison of electrically evoked and channel rhodopsin-evoked postsynaptic potentials in the pharyngeal system of Caenorhabditis elegans.

Franks CJ, Murray C, Ogden D, O'Connor V, Holden-Dye L.

Invert Neurosci. 2009 Mar;9(1):43-56. doi: 10.1007/s10158-009-0088-8. Epub 2009 Mar 18.

PMID:
19294439
45.

UNC-18 modulates ethanol sensitivity in Caenorhabditis elegans.

Graham ME, Edwards MR, Holden-Dye L, Morgan A, Burgoyne RD, Barclay JW.

Mol Biol Cell. 2009 Jan;20(1):43-55. doi: 10.1091/mbc.E08-07-0689. Epub 2008 Oct 15.

46.

The actions of Caenorhabditis elegans neuropeptide-like peptides (NLPs) on body wall muscle of Ascaris suum and pharyngeal muscle of C. elegans.

Papaioannou S, Holden-Dye L, Walker RJ.

Acta Biol Hung. 2008;59 Suppl:189-97. doi: 10.1556/ABiol.59.2008.Suppl.28.

PMID:
18652392
47.

Evidence for a role for cyclic AMP in modulating the action of 5-HT and an excitatory neuropeptide, FLP17A, in the pharyngeal muscle of Caenorhabditis elegans.

Papaioannou S, Holden-Dye L, Walker RJ.

Invert Neurosci. 2008 Jun;8(2):91-100. doi: 10.1007/s10158-008-0072-8. Epub 2008 May 8.

PMID:
18463910
48.

Electrophysiological recordings from the pharynx.

Cook A, Franks CJ, Holden-Dye L.

WormBook. 2006 May 17:1-7. Review. No abstract available.

49.

Anthelmintic drugs.

Holden-Dye L, Walker RJ.

WormBook. 2007 Nov 2:1-13. Review.

50.

SLO, SLO, quick, quick, slow: calcium-activated potassium channels as regulators of Caenorhabditis elegans behaviour and targets for anthelmintics.

Holden-Dye L, O'Connor V, Hopper NA, Walker RJ, Harder A, Bull K, Guest M.

Invert Neurosci. 2007 Dec;7(4):199-208. Epub 2007 Oct 26. Review.

PMID:
17962986

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