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Where to From Here? Is There a Role for Physical Therapists in Enacting Evidence-Based Guidelines for Weight Loss in Adults with Osteoarthritis Who Are Overweight?

Quicke JG, Holden MA, Bennell KL, Allison K.

Phys Ther. 2019 Oct 9. pii: pzz135. doi: 10.1093/ptj/pzz135. [Epub ahead of print] No abstract available.


Improved characterisation of MRSA transmission using within-host bacterial sequence diversity.

Hall MD, Holden MT, Srisomang P, Mahavanakul W, Wuthiekanun V, Limmathurotsakul D, Fountain K, Parkhill J, Nickerson EK, Peacock SJ, Fraser C.

Elife. 2019 Oct 8;8. pii: e46402. doi: 10.7554/eLife.46402. [Epub ahead of print]


Super-Resolution Microscopy Reveals Shape and Distribution of Dislocations in Single-Crystal Nanocomposites.

Ihli J, Green DC, Lynch C, Holden MA, Lee PA, Zhang S, Robinson IK, Webb SED, Meldrum FC.

Angew Chem Int Ed Engl. 2019 Oct 8. doi: 10.1002/anie.201905293. [Epub ahead of print] Review.


Forecasting species range dynamics with process-explicit models: matching methods to applications.

Briscoe NJ, Elith J, Salguero-Gómez R, Lahoz-Monfort JJ, Camac JS, Giljohann KM, Holden MH, Hradsky BA, Kearney MR, McMahon SM, Phillips BL, Regan TJ, Rhodes JR, Vesk PA, Wintle BA, Yen JDL, Guillera-Arroita G.

Ecol Lett. 2019 Nov;22(11):1940-1956. doi: 10.1111/ele.13348. Epub 2019 Jul 29. Review.


Author Correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics.

Davies MR, McIntyre L, Mutreja A, Lacey JA, Lees JA, Towers RJ, Duchêne S, Smeesters PR, Frost HR, Price DJ, Holden MTG, David S, Giffard PM, Worthing KA, Seale AC, Berkley JA, Harris SR, Rivera-Hernandez T, Berking O, Cork AJ, Torres RSLA, Lithgow T, Strugnell RA, Bergmann R, Nitsche-Schmitz P, Chhatwal GS, Bentley SD, Fraser JD, Moreland NJ, Carapetis JR, Steer AC, Parkhill J, Saul A, Williamson DA, Currie BJ, Tong SYC, Dougan G, Walker MJ.

Nat Genet. 2019 Aug;51(8):1295. doi: 10.1038/s41588-019-0482-z.


Encrypted Oligonucleotide Arrays for Molecular Authentication.

Holden MT, Smith LM.

ACS Comb Sci. 2019 Aug 12;21(8):562-567. doi: 10.1021/acscombsci.9b00088. Epub 2019 Jul 15.


Genomic identification of cryptic susceptibility to penicillins and β-lactamase inhibitors in methicillin-resistant Staphylococcus aureus.

Harrison EM, Ba X, Coll F, Blane B, Restif O, Carvell H, Köser CU, Jamrozy D, Reuter S, Lovering A, Gleadall N, Bellis KL, Uhlemann AC, Lowy FD, Massey RC, Grilo IR, Sobral R, Larsen J, Rhod Larsen A, Vingsbo Lundberg C, Parkhill J, Paterson GK, Holden MTG, Peacock SJ, Holmes MA.

Nat Microbiol. 2019 Oct;4(10):1680-1691. doi: 10.1038/s41564-019-0471-0. Epub 2019 Jun 24.


Priorities for the effective implementation of osteoarthritis management programs: an OARSI international consensus exercise.

Eyles JP, Hunter DJ, Bennell KL, Dziedzic KS, Hinman RS, van der Esch M, Holden MA, Bowden JL; Joint Effort Initiative Members.

Osteoarthritis Cartilage. 2019 Sep;27(9):1270-1279. doi: 10.1016/j.joca.2019.05.015. Epub 2019 Jun 1.


Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics.

Davies MR, McIntyre L, Mutreja A, Lacey JA, Lees JA, Towers RJ, Duchêne S, Smeesters PR, Frost HR, Price DJ, Holden MTG, David S, Giffard PM, Worthing KA, Seale AC, Berkley JA, Harris SR, Rivera-Hernandez T, Berking O, Cork AJ, Torres RSLA, Lithgow T, Strugnell RA, Bergmann R, Nitsche-Schmitz P, Chhatwal GS, Bentley SD, Fraser JD, Moreland NJ, Carapetis JR, Steer AC, Parkhill J, Saul A, Williamson DA, Currie BJ, Tong SYC, Dougan G, Walker MJ.

Nat Genet. 2019 Jun;51(6):1035-1043. doi: 10.1038/s41588-019-0417-8. Epub 2019 May 27. Erratum in: Nat Genet. 2019 Jul 19;:.


The mesoscavenger release hypothesis and implications for ecosystem and human well-being.

O'Bryan CJ, Holden MH, Watson JEM.

Ecol Lett. 2019 Sep;22(9):1340-1348. doi: 10.1111/ele.13288. Epub 2019 May 27.


Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.

Zhang Y, Jang Y, Lee JE, Ahn J, Xu L, Holden MR, Cornett EM, Krajewski K, Klein BJ, Wang SP, Dou Y, Roeder RG, Strahl BD, Rothbart SB, Shi X, Ge K, Kutateladze TG.

Nat Commun. 2019 May 24;10(1):2314. doi: 10.1038/s41467-019-10324-8.


Wanted: automated objective proficiency assessment metrics for the FAST exam (and other POCUS studies).

Bell CR, Holden MS.

Eur J Trauma Emerg Surg. 2019 Aug;45(4):763-764. doi: 10.1007/s00068-019-01156-8. Epub 2019 May 22. No abstract available.


Impact of omalizumab on patient-reported outcomes in chronic idiopathic urticaria: Results from a randomized study (XTEND-CIU).

Casale TB, Murphy TR, Holden M, Rajput Y, Yoo B, Bernstein JA.

J Allergy Clin Immunol Pract. 2019 Sep - Oct;7(7):2487-2490.e1. doi: 10.1016/j.jaip.2019.04.020. Epub 2019 Apr 26. No abstract available.


Machine learning methods for automated technical skills assessment with instructional feedback in ultrasound-guided interventions.

Holden MS, Xia S, Lia H, Keri Z, Bell C, Patterson L, Ungi T, Fichtinger G.

Int J Comput Assist Radiol Surg. 2019 Nov;14(11):1993-2003. doi: 10.1007/s11548-019-01977-3. Epub 2019 Apr 20.


Mechanism for autoinhibition and activation of the MORC3 ATPase.

Zhang Y, Klein BJ, Cox KL, Bertulat B, Tencer AH, Holden MR, Wright GM, Black J, Cardoso MC, Poirier MG, Kutateladze TG.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6111-6119. doi: 10.1073/pnas.1819524116. Epub 2019 Mar 8.


A qualitative study exploring the views of individuals with knee osteoarthritis on the role of physiotherapists in weight management: A complex issue requiring a sophisticated skill set.

Allison K, Delany C, Setchell J, Egerton T, Holden M, Quicke J, Bennell K.

Musculoskeletal Care. 2019 Jun;17(2):206-214. doi: 10.1002/msc.1391. Epub 2019 Mar 1.


Visualization of the effect of additives on the nanostructures of individual bio-inspired calcite crystals.

Ihli J, Clark JN, Kanwal N, Kim YY, Holden MA, Harder RJ, Tang CC, Ashbrook SE, Robinson IK, Meldrum FC.

Chem Sci. 2018 Nov 9;10(4):1176-1185. doi: 10.1039/c8sc03733g. eCollection 2019 Jan 28.


High-speed imaging of ice nucleation in water proves the existence of active sites.

Holden MA, Whale TF, Tarn MD, O'Sullivan D, Walshaw RD, Murray BJ, Meldrum FC, Christenson HK.

Sci Adv. 2019 Feb 1;5(2):eaav4316. doi: 10.1126/sciadv.aav4316. eCollection 2019 Feb.


Reply to 'Consider species specialism when publishing datasets' and 'Decision trees for data publishing may exacerbate conservation conflict'.

Tulloch AIT, Auerbach N, Avery-Gomm S, Dickman CR, Fisher DO, Grantham H, Holden MH, Lavery TH, Leseberg NP, O'Connor J, Roberson L, Smyth AK, Stone Z, Tulloch V, Turak E, Watson JEM, Wardle GM.

Nat Ecol Evol. 2019 Mar;3(3):320-321. doi: 10.1038/s41559-019-0805-6. No abstract available.


How do UK physiotherapists address weight loss among individuals with hip osteoarthritis? A mixed-methods study.

Holden MA, Waterfield J, Whittle R, Bennell K, Quicke JG, Chesterton L, Mallen CD.

Musculoskeletal Care. 2019 Mar;17(1):133-144. doi: 10.1002/msc.1383. Epub 2019 Jan 21.


Controlling the fluorescence and room-temperature phosphorescence behaviour of carbon nanodots with inorganic crystalline nanocomposites.

Green DC, Holden MA, Levenstein MA, Zhang S, Johnson BRG, Gala de Pablo J, Ward A, Botchway SW, Meldrum FC.

Nat Commun. 2019 Jan 14;10(1):206. doi: 10.1038/s41467-018-08214-6.


Molecular epidemiology and expression of capsular polysaccharides in Staphylococcus aureus clinical isolates in the United States.

Mohamed N, Timofeyeva Y, Jamrozy D, Rojas E, Hao L, Silmon de Monerri NC, Hawkins J, Singh G, Cai B, Liberator P, Sebastian S, Donald RGK, Scully IL, Jones CH, Creech CB, Thomsen I, Parkhill J, Peacock SJ, Jansen KU, Holden MTG, Anderson AS.

PLoS One. 2019 Jan 14;14(1):e0208356. doi: 10.1371/journal.pone.0208356. eCollection 2019.


Time-resolved multirotational dynamics of single solution-phase tau proteins reveals details of conformational variation.

Foote AK, Manger LH, Holden MR, Margittai M, Goldsmith RH.

Phys Chem Chem Phys. 2019 Jan 23;21(4):1863-1871. doi: 10.1039/c8cp06971a.


Chlorhexidine and octenidine use, carriage of qac genes, and reduced antiseptic susceptibility in methicillin-resistant Staphylococcus aureus isolates from a healthcare network.

Htun HL, Hon PY, Holden MTG, Ang B, Chow A.

Clin Microbiol Infect. 2019 Sep;25(9):1154.e1-1154.e7. doi: 10.1016/j.cmi.2018.12.036. Epub 2019 Jan 6.


Surgery Tutor for Computational Assessment of Technical Proficiency in Soft-Tissue Tumor Resection in a Simulated Setting.

Yeo CT, Ring J, Holden MS, Ungi T, Toprak A, Fichtinger G, Zevin B.

J Surg Educ. 2019 May - Jun;76(3):872-880. doi: 10.1016/j.jsurg.2018.11.005. Epub 2018 Dec 17.


Association Between 6-Week Postdischarge Risk Classification and 12-Month Outcomes After Orthopedic Trauma.

Castillo RC, Huang Y, Scharfstein D, Frey K, Bosse MJ, Pollak AN, Vallier HA, Archer KR, Hymes RA, Newcomb AB, MacKenzie EJ, Wegener S; and the Major Extremity Trauma Research Consortium (METRC), Hsu JR, Karunakar MA, Seymour RB, Sims SH, Flores E, Churchill C, Hak DJ, Henderson CE, Mir HR, Chan DS, Shah AR, Steverson B, Westberg J, Gary JL, Achor TS, Choo A, Munz JW, Porrey M, Hendrickson S, Breslin MA, McKinley TO, Gaski GE, Kempton LB, Sorkin AT, Virkus WW, Hill LC, Jones CB, Sietsema DL, O'Toole RV, Ordonio K, Howe AL, Zerhusen TJ Jr, Obremskey W, Boyce RH, Jahangir AA, Molina CS, Sethi MK, Vanston SW, Carroll EA, Drye DY, Holden MB, Collins SC, Wysocki E.

JAMA Surg. 2019 Feb 1;154(2):e184824. doi: 10.1001/jamasurg.2018.4824. Epub 2019 Feb 20.


Unravelling the origins of ice nucleation on organic crystals.

Sosso GC, Whale TF, Holden MA, Pedevilla P, Murray BJ, Michaelides A.

Chem Sci. 2018 Aug 27;9(42):8077-8088. doi: 10.1039/c8sc02753f. eCollection 2018 Nov 14.


Antimicrobial resistance in atopic dermatitis: Need for an urgent rethink.

Harkins CP, Holden MTG, Irvine AD.

Ann Allergy Asthma Immunol. 2019 Mar;122(3):236-240. doi: 10.1016/j.anai.2018.11.027. Epub 2018 Nov 29. No abstract available.


Evaluation of a prompt card for community pharmacists performing consultations with patients on anticoagulation - lessons learned.

Arnet I, Holden M, Antoniou S; iPACT group (International Pharmacists for Anticoagulation Care Taskforce).

Pharm Pract (Granada). 2018 Jul-Sep;16(3):1244. doi: 10.18549/PharmPract.2018.03.1244. Epub 2018 Sep 18.


Cognitive load theory as a framework for simulation-based, ultrasound-guided internal jugular catheterization training: Once is not enough.

McGraw R, Chaplin T, Rocca N, Rang L, Jaeger M, Holden M, Keri Z, Fichtinger G.

CJEM. 2019 Jan;21(1):141-148. doi: 10.1017/cem.2018.456. Epub 2018 Nov 8.


ZZ-dependent regulation of p62/SQSTM1 in autophagy.

Zhang Y, Mun SR, Linares JF, Ahn J, Towers CG, Ji CH, Fitzwalter BE, Holden MR, Mi W, Shi X, Moscat J, Thorburn A, Diaz-Meco MT, Kwon YT, Kutateladze TG.

Nat Commun. 2018 Oct 22;9(1):4373. doi: 10.1038/s41467-018-06878-8.


Mobile-Genetic-Element-Encoded Hypertolerance to Copper Protects Staphylococcus aureus from Killing by Host Phagocytes.

Zapotoczna M, Riboldi GP, Moustafa AM, Dickson E, Narechania A, Morrissey JA, Planet PJ, Holden MTG, Waldron KJ, Geoghegan JA.

MBio. 2018 Oct 16;9(5). pii: e00550-18. doi: 10.1128/mBio.00550-18.


Identification and Evaluation of Self-Report Physical Activity Instruments in Adults With Osteoarthritis: A Systematic Review.

Smith RD, Dziedzic KS, Quicke JG, Holden MA, McHugh GA, Healey EL.

Arthritis Care Res (Hoboken). 2019 Feb;71(2):237-251. doi: 10.1002/acr.23787.


A mixed methods exploration of physiotherapist's approaches to analgesic use among patients with hip osteoarthritis.

Holden MA, Whittle R, Waterfield J, Chesterton L, Cottrell E, Quicke JG, Mallen CD.

Physiotherapy. 2019 Sep;105(3):328-337. doi: 10.1016/ Epub 2018 Aug 17.


Contributions of biogenic material to the atmospheric ice-nucleating particle population in North Western Europe.

O'Sullivan D, Adams MP, Tarn MD, Harrison AD, Vergara-Temprado J, Porter GCE, Holden MA, Sanchez-Marroquin A, Carotenuto F, Whale TF, McQuaid JB, Walshaw R, Hedges DHP, Burke IT, Cui Z, Murray BJ.

Sci Rep. 2018 Sep 14;8(1):13821. doi: 10.1038/s41598-018-31981-7.


Correction: The enhancement and suppression of immersion mode heterogeneous ice-nucleation by solutes.

Whale TF, Holden MA, Wilson TW, O'Sullivan D, Murray BJ.

Chem Sci. 2018 Jul 12;9(29):6313. doi: 10.1039/c8sc90139b. eCollection 2018 Aug 7.


Each pregnancy linearly changes immune gene expression in the blood of healthy women compared with breast cancer patients.

Lund E, Nakamura A, Snapkov I, Thalabard JC, Olsen KS, Holden L, Holden M.

Clin Epidemiol. 2018 Aug 6;10:931-940. doi: 10.2147/CLEP.S163208. eCollection 2018.


Sonographic Accuracy as a Novel Tool for Point-of-care Ultrasound Competency Assessment.

Bell CR, McKaigney CJ, Holden M, Fichtinger G, Rang L.

AEM Educ Train. 2017 Sep 27;1(4):316-324. doi: 10.1002/aet2.10064. eCollection 2017 Oct.


Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials.

Hay E, Dziedzic K, Foster N, Peat G, van der Windt D, Bartlam B, Blagojevic-Bucknall M, Edwards J, Healey E, Holden M, Hughes R, Jinks C, Jordan K, Jowett S, Lewis M, Mallen C, Morden A, Nicholls E, Ong BN, Porcheret M, Wulff J, Kigozi J, Oppong R, Paskins Z, Croft P.

Southampton (UK): NIHR Journals Library; 2018 Jul.


Global Scale Dissemination of ST93: A Divergent Staphylococcus aureus Epidemic Lineage That Has Recently Emerged From Remote Northern Australia.

van Hal SJ, Steinig EJ, Andersson P, Holden MTG, Harris SR, Nimmo GR, Williamson DA, Heffernan H, Ritchie SR, Kearns AM, Ellington MJ, Dickson E, de Lencastre H, Coombs GW, Bentley SD, Parkhill J, Holt DC, Giffard PM, Tong SYC.

Front Microbiol. 2018 Jul 9;9:1453. doi: 10.3389/fmicb.2018.01453. eCollection 2018.


A decision tree for assessing the risks and benefits of publishing biodiversity data.

Tulloch AIT, Auerbach N, Avery-Gomm S, Bayraktarov E, Butt N, Dickman CR, Ehmke G, Fisher DO, Grantham H, Holden MH, Lavery TH, Leseberg NP, Nicholls M, O'Connor J, Roberson L, Smyth AK, Stone Z, Tulloch V, Turak E, Wardle GM, Watson JEM.

Nat Ecol Evol. 2018 Aug;2(8):1209-1217. doi: 10.1038/s41559-018-0608-1. Epub 2018 Jul 23. Review.


Gene exchange drives the ecological success of a multi-host bacterial pathogen.

Richardson EJ, Bacigalupe R, Harrison EM, Weinert LA, Lycett S, Vrieling M, Robb K, Hoskisson PA, Holden MTG, Feil EJ, Paterson GK, Tong SYC, Shittu A, van Wamel W, Aanensen DM, Parkhill J, Peacock SJ, Corander J, Holmes M, Fitzgerald JR.

Nat Ecol Evol. 2018 Sep;2(9):1468-1478. doi: 10.1038/s41559-018-0617-0. Epub 2018 Jul 23.


Naturally occurring polymorphisms in the virulence regulator Rsp modulate Staphylococcus aureus survival in blood and antibiotic susceptibility.

Krishna A, Holden MTG, Peacock SJ, Edwards AM, Wigneshweraraj S.

Microbiology. 2018 Sep;164(9):1189-1195. doi: 10.1099/mic.0.000695. Epub 2018 Jul 20.


A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol.

Paskins Z, Hughes G, Myers H, Hughes E, Hennings S, Cherrington A, Evans A, Holden M, Stevenson K, Menon A, Bromley K, Roberts P, Hall A, Peat G, Jinks C, Oppong R, Lewis M, Foster NE, Mallen C, Roddy E.

BMC Musculoskelet Disord. 2018 Jul 18;19(1):218. doi: 10.1186/s12891-018-2153-0.


Meningococcal serogroup B outbreak response University of Wisconsin-Madison.

Ritscher AM, Ranum N, Malak JD, Ahrabi-Fard S, Baird J, Berti AD, Curtis W, Holden M, Jones CD, Kind J, Kinsey W, Koepke R, Schauer SL, Stein E, Van Orman S, Ward BG, Zahner SJ, Hayney MS.

J Am Coll Health. 2019 Apr;67(3):191-196. doi: 10.1080/07448481.2018.1469502. Epub 2018 Sep 19.


Is Black Carbon an Unimportant Ice-Nucleating Particle in Mixed-Phase Clouds?

Vergara-Temprado J, Holden MA, Orton TR, O'Sullivan D, Umo NS, Browse J, Reddington C, Baeza-Romero MT, Jones JM, Lea-Langton A, Williams A, Carslaw KS, Murray BJ.

J Geophys Res Atmos. 2018 Apr 27;123(8):4273-4283. doi: 10.1002/2017JD027831. Epub 2018 Apr 26.


Genetic analysis of invasive Escherichia coli in Scotland reveals determinants of healthcare-associated versus community-acquired infections.

Goswami C, Fox S, Holden M, Connor M, Leanord A, Evans TJ.

Microb Genom. 2018 Jun;4(6). doi: 10.1099/mgen.0.000190. Epub 2018 Jun 22.


Comparative sequence analysis of the capsular polysaccharide loci of Actinobacillus pleuropneumoniae serovars 1-18, and development of two multiplex PCRs for comprehensive capsule typing.

Bossé JT, Li Y, Fernandez Crespo R, Lacouture S, Gottschalk M, Sárközi R, Fodor L, Casas Amoribieta M, Angen Ø, Nedbalcova K, Holden MTG, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR; BRaDP1T consortium.

Vet Microbiol. 2018 Jul;220:83-89. doi: 10.1016/j.vetmic.2018.05.011. Epub 2018 May 20.


Defining adherence to therapeutic exercise for musculoskeletal pain: a systematic review.

Bailey DL, Holden MA, Foster NE, Quicke JG, Haywood KL, Bishop A.

Br J Sports Med. 2018 Jun 6. pii: bjsports-2017-098742. doi: 10.1136/bjsports-2017-098742. [Epub ahead of print] Review.


Rearing and Long-Term Maintenance of Eristalis tenax Hoverflies for Research Studies.

Nicholas S, Thyselius M, Holden M, Nordström K.

J Vis Exp. 2018 May 19;(135). doi: 10.3791/57711.

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