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Items: 1 to 50 of 132

1.

Is commercial harvesting of beach-cast seaweed ecologically sustainable?

Holden JJ, Dudas SE, Juanes F.

Integr Environ Assess Manag. 2016 Oct;12(4):825-7. doi: 10.1002/ieam.1795. No abstract available.

PMID:
27640421
2.

Trends in extinction risk for imperiled species in Canada.

Favaro B, Claar DC, Fox CH, Freshwater C, Holden JJ, Roberts A; UVic Research Derby.

PLoS One. 2014 Nov 17;9(11):e113118. doi: 10.1371/journal.pone.0113118. eCollection 2014.

3.

DRD2 and PPP1R1B (DARPP-32) polymorphisms independently confer increased risk for autism spectrum disorders and additively predict affected status in male-only affected sib-pair families.

Hettinger JA, Liu X, Hudson ML, Lee A, Cohen IL, Michaelis RC, Schwartz CE, Lewis SM, Holden JJ.

Behav Brain Funct. 2012 May 4;8:19. doi: 10.1186/1744-9081-8-19.

4.

Developmental trajectories in syndromes with intellectual disability, with a focus on Wolf-Hirschhorn and its cognitive-behavioral profile.

Fisch GS, Carpenter N, Howard-Peebles PN, Holden JJ, Tarleton J, Simensen R, Battaglia A.

Am J Intellect Dev Disabil. 2012 Mar;117(2):167-79. doi: 10.1352/1944-7558-117.2.167.

PMID:
22515830
5.

Correlates of age at diagnosis of autism spectrum disorders in six Canadian regions.

Coo H, Ouellette-Kuntz H, Lam M, Yu CT, Dewey D, Bernier FP, Chudley AE, Hennessey PE, Breitenbach MM, Noonan AL, Lewis ME, Holden JJ.

Chronic Dis Inj Can. 2012 Mar;32(2):90-100.

6.

Status report - National Epidemiologic Database for the Study of Autism in Canada (NEDSAC).

Ouellette-Kuntz H, Coo H, Yu CT, Lewis ME, Dewey D, Hennessey PE, Jackman PD, Breitenbach MM, Holden JJ.

Chronic Dis Inj Can. 2012 Mar;32(2):84-9. No abstract available.

7.

Clinical application of 2.7M Cytogenetics array for CNV detection in subjects with idiopathic autism and/or intellectual disability.

Qiao Y, Tyson C, Hrynchak M, Lopez-Rangel E, Hildebrand J, Martell S, Fawcett C, Kasmara L, Calli K, Harvard C, Liu X, Holden JJ, Lewis SM, Rajcan-Separovic E.

Clin Genet. 2013 Feb;83(2):145-54. doi: 10.1111/j.1399-0004.2012.01860.x. Epub 2012 Apr 9.

PMID:
22369279
8.

Dopamine receptor D4 gene variation predicts preschoolers' developing theory of mind.

Lackner C, Sabbagh MA, Hallinan E, Liu X, Holden JJ.

Dev Sci. 2012 Mar;15(2):272-80. doi: 10.1111/j.1467-7687.2011.01124.x. Epub 2011 Dec 3.

PMID:
22356182
9.

Association of GTF2i in the Williams-Beuren syndrome critical region with autism spectrum disorders.

Malenfant P, Liu X, Hudson ML, Qiao Y, Hrynchak M, Riendeau N, Hildebrand MJ, Cohen IL, Chudley AE, Forster-Gibson C, Mickelson EC, Rajcan-Separovic E, Lewis ME, Holden JJ.

J Autism Dev Disord. 2012 Jul;42(7):1459-69. doi: 10.1007/s10803-011-1389-4.

PMID:
22048961
10.

Understanding the impact of 1q21.1 copy number variant.

Harvard C, Strong E, Mercier E, Colnaghi R, Alcantara D, Chow E, Martell S, Tyson C, Hrynchak M, McGillivray B, Hamilton S, Marles S, Mhanni A, Dawson AJ, Pavlidis P, Qiao Y, Holden JJ, Lewis SM, O'Driscoll M, Rajcan-Separovic E.

Orphanet J Rare Dis. 2011 Aug 8;6:54. doi: 10.1186/1750-1172-6-54.

11.

2p15-p16.1 microdeletion syndrome: molecular characterization and association of the OTX1 and XPO1 genes with autism spectrum disorders.

Liu X, Malenfant P, Reesor C, Lee A, Hudson ML, Harvard C, Qiao Y, Persico AM, Cohen IL, Chudley AE, Forster-Gibson C, Rajcan-Separovic E, Lewis ME, Holden JJ.

Eur J Hum Genet. 2011 Dec;19(12):1264-70. doi: 10.1038/ejhg.2011.112. Epub 2011 Jul 13.

12.

Development and initial validation of a parent report measure of the behavioral development of infants at risk for autism spectrum disorders.

Feldman MA, Ward RA, Savona D, Regehr K, Parker K, Hudson M, Penning H, Holden JJ.

J Autism Dev Disord. 2012 Jan;42(1):13-22. doi: 10.1007/s10803-011-1208-y.

PMID:
21387111
13.

Population- and family-based studies associate the MTHFR gene with idiopathic autism in simplex families.

Liu X, Solehdin F, Cohen IL, Gonzalez MG, Jenkins EC, Lewis ME, Holden JJ.

J Autism Dev Disord. 2011 Jul;41(7):938-44. doi: 10.1007/s10803-010-1120-x.

PMID:
21069446
14.

Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability.

Noor A, Whibley A, Marshall CR, Gianakopoulos PJ, Piton A, Carson AR, Orlic-Milacic M, Lionel AC, Sato D, Pinto D, Drmic I, Noakes C, Senman L, Zhang X, Mo R, Gauthier J, Crosbie J, Pagnamenta AT, Munson J, Estes AM, Fiebig A, Franke A, Schreiber S, Stewart AF, Roberts R, McPherson R, Guter SJ, Cook EH Jr, Dawson G, Schellenberg GD, Battaglia A, Maestrini E; Autism Genome Project Consortium, Jeng L, Hutchison T, Rajcan-Separovic E, Chudley AE, Lewis SM, Liu X, Holden JJ, Fernandez B, Zwaigenbaum L, Bryson SE, Roberts W, Szatmari P, Gallagher L, Stratton MR, Gecz J, Brady AF, Schwartz CE, Schachar RJ, Monaco AP, Rouleau GA, Hui CC, Lucy Raymond F, Scherer SW, Vincent JB.

Sci Transl Med. 2010 Sep 15;2(49):49ra68. doi: 10.1126/scitranslmed.3001267.

15.

Autism severity is associated with child and maternal MAOA genotypes.

Cohen IL, Liu X, Lewis ME, Chudley A, Forster-Gibson C, Gonzalez M, Jenkins EC, Brown WT, Holden JJ.

Clin Genet. 2011 Apr;79(4):355-62. doi: 10.1111/j.1399-0004.2010.01471.x.

PMID:
20573161
16.

Outcome of array CGH analysis for 255 subjects with intellectual disability and search for candidate genes using bioinformatics.

Qiao Y, Harvard C, Tyson C, Liu X, Fawcett C, Pavlidis P, Holden JJ, Lewis ME, Rajcan-Separovic E.

Hum Genet. 2010 Aug;128(2):179-94. doi: 10.1007/s00439-010-0837-0. Epub 2010 May 29.

PMID:
20512354
17.

The course of cognitive-behavioral development in children with the FMR1 mutation, Williams-Beuren syndrome, and neurofibromatosis type 1: The effect of gender.

Fisch GS, Carpenter N, Howard-Peebles PN, Holden JJ, Tarleton J, Simensen R.

Am J Med Genet A. 2010 Jun;152A(6):1498-509. doi: 10.1002/ajmg.a.33412.

PMID:
20503326
18.

Association of MAOA, 5-HTT, and NET promoter polymorphisms with gene expression and protein activity in human placentas.

Zhang H, Smith GN, Liu X, Holden JJ.

Physiol Genomics. 2010 Jun;42(1):85-92. doi: 10.1152/physiolgenomics.00220.2009. Epub 2010 Mar 23.

19.

Brief report: telephone administration of the autism diagnostic interview--revised: reliability and suitability for use in research.

Ward-King J, Cohen IL, Penning H, Holden JJ.

J Autism Dev Disord. 2010 Oct;40(10):1285-90. doi: 10.1007/s10803-010-0987-x.

PMID:
20195733
20.

Age at diagnosis of autism spectrum disorders in four regions of Canada.

Ouellette-Kuntz HM, Coo H, Lam M, Yu CT, Breitenbach MM, Hennessey PE, Holden JJ, Brown HK, Noonan AL, Gauthier RB, Crews LR.

Can J Public Health. 2009 Jul-Aug;100(4):268-73.

PMID:
19722339
21.

Phenomic determinants of genomic variation in autism spectrum disorders.

Qiao Y, Riendeau N, Koochek M, Liu X, Harvard C, Hildebrand MJ, Holden JJ, Rajcan-Separovic E, Lewis ME.

J Med Genet. 2009 Oct;46(10):680-8. doi: 10.1136/jmg.2009.066795. Epub 2009 Jul 21.

PMID:
19625284
22.

Submicroscopic deletions of 11q24-25 in individuals without Jacobsen syndrome: re-examination of the critical region by high-resolution array-CGH.

Tyson C, Qiao Y, Harvard C, Liu X, Bernier FP, McGillivray B, Farrell SA, Arbour L, Chudley AE, Clarke L, Gibson W, Dyack S, McLeod R, Costa T, Vanallen MI, Yong SL, Graham GE, Macleod P, Patel MS, Hurlburt J, Holden JJ, Lewis SM, Rajcan-Separovic E.

Mol Cytogenet. 2008 Nov 11;1:23. doi: 10.1186/1755-8166-1-23.

23.

The DLX1and DLX2 genes and susceptibility to autism spectrum disorders.

Liu X, Novosedlik N, Wang A, Hudson ML, Cohen IL, Chudley AE, Forster-Gibson CJ, Lewis SM, Holden JJ.

Eur J Hum Genet. 2009 Feb;17(2):228-35. doi: 10.1038/ejhg.2008.148. Epub 2008 Aug 27.

24.

Using cluster ensemble and validation to identify subtypes of pervasive developmental disorders.

Shen JJ, Lee PH, Holden JJ, Shatkay H.

AMIA Annu Symp Proc. 2007 Oct 11:666-70.

25.

Autism-associated familial microdeletion of Xp11.22.

Qiao Y, Liu X, Harvard C, Hildebrand MJ, Rajcan-Separovic E, Holden JJ, Lewis ME.

Clin Genet. 2008 Aug;74(2):134-44. doi: 10.1111/j.1399-0004.2008.01028.x. Epub 2008 May 21.

PMID:
18498374
26.

Face-brain asymmetry in autism spectrum disorders.

Hammond P, Forster-Gibson C, Chudley AE, Allanson JE, Hutton TJ, Farrell SA, McKenzie J, Holden JJ, Lewis ME.

Mol Psychiatry. 2008 Jun;13(6):614-23. doi: 10.1038/mp.2008.18. Epub 2008 Mar 4.

PMID:
18317467
27.

A DRD1 haplotype is associated with risk for autism spectrum disorders in male-only affected sib-pair families.

Hettinger JA, Liu X, Schwartz CE, Michaelis RC, Holden JJ.

Am J Med Genet B Neuropsychiatr Genet. 2008 Jul 5;147B(5):628-36. doi: 10.1002/ajmg.b.30655.

PMID:
18205172
28.

Putatively benign copy number variants in subjects with idiopathic autism spectrum disorder and/or intellectual disability.

Qiao Y, Harvard C, Riendeau N, Fawcett C, Liu X, Holden JJ, Lewis ME, Rajcan-Separovic E.

Cytogenet Genome Res. 2008;123(1-4):79-87. doi: 10.1159/000184694. Epub 2009 Mar 11.

PMID:
19287141
29.

Trends in autism prevalence: diagnostic substitution revisited.

Coo H, Ouellette-Kuntz H, Lloyd JE, Kasmara L, Holden JJ, Lewis ME.

J Autism Dev Disord. 2008 Jul;38(6):1036-46. Epub 2007 Nov 2.

PMID:
17975721
30.

Studies of age-correlated features of cognitive-behavioral development in children and adolescents with genetic disorders.

Fisch GS, Carpenter N, Howard-Peebles PN, Holden JJ, Tarleton J, Simensen R, Nance W.

Am J Med Genet A. 2007 Oct 15;143A(20):2478-89.

PMID:
17853466
31.

Large-scale copy number variants (CNVs): distribution in normal subjects and FISH/real-time qPCR analysis.

Qiao Y, Liu X, Harvard C, Nolin SL, Brown WT, Koochek M, Holden JJ, Lewis ME, Rajcan-Separovic E.

BMC Genomics. 2007 Jun 12;8:167.

32.

The G22A polymorphism of the ADA gene and susceptibility to autism spectrum disorders.

Hettinger JA, Liu X, Holden JJ.

J Autism Dev Disord. 2008 Jan;38(1):14-9. Epub 2007 Mar 6.

PMID:
17340203
33.

Trends in special education code assignment for autism: implications for prevalence estimates.

Ouellette-Kuntz H, Coo H, Lloyd JE, Kasmara L, Holden JJ, Lewis ME.

J Autism Dev Disord. 2007 Nov;37(10):1941-8. Epub 2007 Jan 11.

PMID:
17216561
34.

Clinical and molecular cytogenetic characterisation of a newly recognised microdeletion syndrome involving 2p15-16.1.

Rajcan-Separovic E, Harvard C, Liu X, McGillivray B, Hall JG, Qiao Y, Hurlburt J, Hildebrand J, Mickelson EC, Holden JJ, Lewis ME.

J Med Genet. 2007 Apr;44(4):269-76. Epub 2006 Sep 8.

35.

Parental perspectives on the causes of an autism spectrum disorder in their children.

Mercer L, Creighton S, Holden JJ, Lewis ME.

J Genet Couns. 2006 Feb;15(1):41-50.

PMID:
16547798
36.

15q duplication associated with autism in a multiplex family with a familial cryptic translocation t(14;15)(q11.2;q13.3) detected using array-CGH.

Koochek M, Harvard C, Hildebrand MJ, Van Allen M, Wingert H, Mickelson E, Holden JJ, Rajcan-Separovic E, Lewis ME.

Clin Genet. 2006 Feb;69(2):124-34.

PMID:
16433693
38.

Addressing health disparities through promoting equity for individuals with intellectual disability.

Ouellette-Kuntz H, Garcin N, Lewis ME, Minnes P, Martin C, Holden JJ.

Can J Public Health. 2005 Mar-Apr;96 Suppl 2:S8-22. Review.

PMID:
16078552
39.

Paraoxonase gene variants are associated with autism in North America, but not in Italy: possible regional specificity in gene-environment interactions.

D'Amelio M, Ricci I, Sacco R, Liu X, D'Agruma L, Muscarella LA, Guarnieri V, Militerni R, Bravaccio C, Elia M, Schneider C, Melmed R, Trillo S, Pascucci T, Puglisi-Allegra S, Reichelt KL, Macciardi F, Holden JJ, Persico AM.

Mol Psychiatry. 2005 Nov;10(11):1006-16.

PMID:
16027737
40.

XLMR in MRX families 29, 32, 33 and 38 results from the dup24 mutation in the ARX (Aristaless related homeobox) gene.

Stepp ML, Cason AL, Finnis M, Mangelsdorf M, Holinski-Feder E, Macgregor D, MacMillan A, Holden JJ, Gecz J, Stevenson RE, Schwartz CE.

BMC Med Genet. 2005 Apr 25;6:16.

41.

A variant Cri du Chat phenotype and autism spectrum disorder in a subject with de novo cryptic microdeletions involving 5p15.2 and 3p24.3-25 detected using whole genomic array CGH.

Harvard C, Malenfant P, Koochek M, Creighton S, Mickelson EC, Holden JJ, Lewis ME, Rajcan-Separovic E.

Clin Genet. 2005 Apr;67(4):341-51.

PMID:
15733271
42.

FMR1 alleles in Tasmania: a screening study of the special educational needs population.

Mitchell RJ, Holden JJ, Zhang C, Curlis Y, Slater HR, Burgess T, Kirkby KC, Carmichael A, Heading KD, Loesch DZ.

Clin Genet. 2005 Jan;67(1):38-46.

PMID:
15617547
43.

Differential impact of the FMR1 gene on visual processing in fragile X syndrome.

Kogan CS, Boutet I, Cornish K, Zangenehpour S, Mullen KT, Holden JJ, Der Kaloustian VM, Andermann E, Chaudhuri A.

Brain. 2004 Mar;127(Pt 3):591-601. Epub 2004 Jan 21.

PMID:
14736752
44.

Association of autism severity with a monoamine oxidase A functional polymorphism.

Cohen IL, Liu X, Schutz C, White BN, Jenkins EC, Brown WT, Holden JJ.

Clin Genet. 2003 Sep;64(3):190-7.

PMID:
12919132
45.

Behavioral relationship between autism and fragile x syndrome.

Demark JL, Feldman MA, Holden JJ.

Am J Ment Retard. 2003 Sep;108(5):314-26.

PMID:
12901707
46.

Reelin gene alleles and susceptibility to autism spectrum disorders.

Zhang H, Liu X, Zhang C, Mundo E, Macciardi F, Grayson DR, Guidotti AR, Holden JJ.

Mol Psychiatry. 2002;7(9):1012-7.

47.

Autism and the X chromosome: no linkage to microsatellite loci detected using the affected sibling pair method.

Schutz CK, Polley D, Robinson PD, Chalifoux M, Macciardi F, White BN, Holden JJ.

Am J Med Genet. 2002 Apr 15;109(1):36-41.

PMID:
11932990
48.
49.

Genetic diversity at the FMR1 locus in the Indonesian population.

Faradz SM, Pattiiha MZ, Leigh DA, Jenkins M, Leggo J, Buckley MF, Holden JJ.

Ann Hum Genet. 2000 Jul;64(Pt 4):329-39.

50.

Genetically determined low maternal serum dopamine beta-hydroxylase levels and the etiology of autism spectrum disorders.

Robinson PD, Schutz CK, Macciardi F, White BN, Holden JJ.

Am J Med Genet. 2001 Apr 15;100(1):30-6.

PMID:
11337745

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