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Items: 1 to 50 of 151

1.

A global assessment of marine heatwaves and their drivers.

Holbrook NJ, Scannell HA, Sen Gupta A, Benthuysen JA, Feng M, Oliver ECJ, Alexander LV, Burrows MT, Donat MG, Hobday AJ, Moore PJ, Perkins-Kirkpatrick SE, Smale DA, Straub SC, Wernberg T.

Nat Commun. 2019 Jun 14;10(1):2624. doi: 10.1038/s41467-019-10206-z.

PMID:
31201309
2.

Longer and more frequent marine heatwaves over the past century.

Oliver ECJ, Donat MG, Burrows MT, Moore PJ, Smale DA, Alexander LV, Benthuysen JA, Feng M, Sen Gupta A, Hobday AJ, Holbrook NJ, Perkins-Kirkpatrick SE, Scannell HA, Straub SC, Wernberg T.

Nat Commun. 2018 Apr 10;9(1):1324. doi: 10.1038/s41467-018-03732-9.

3.

The unprecedented 2015/16 Tasman Sea marine heatwave.

Oliver ECJ, Benthuysen JA, Bindoff NL, Hobday AJ, Holbrook NJ, Mundy CN, Perkins-Kirkpatrick SE.

Nat Commun. 2017 Jul 14;8:16101. doi: 10.1038/ncomms16101.

4.

Developing rural community health risk assessments for climate change: a Tasmanian pilot study.

Bell EJ, Turner P, Meinke H, Holbrook NJ.

Rural Remote Health. 2015 Jul-Sep;15(3):3174. Epub 2015 Sep 22. Review.

5.

Species traits and climate velocity explain geographic range shifts in an ocean-warming hotspot.

Sunday JM, Pecl GT, Frusher S, Hobday AJ, Hill N, Holbrook NJ, Edgar GJ, Stuart-Smith R, Barrett N, Wernberg T, Watson RA, Smale DA, Fulton EA, Slawinski D, Feng M, Radford BT, Thompson PA, Bates AE.

Ecol Lett. 2015 Sep;18(9):944-53. doi: 10.1111/ele.12474. Epub 2015 Jul 20.

PMID:
26189556
6.

Oceanic variability and coastal topography shape genetic structure in a long-dispersing sea urchin.

Banks SC, Piggott LM, Williamson JE, Bové U, Holbrook NJ, Beheregaray LB.

Ecology. 2007 Dec;88(12):3055-64.

PMID:
18229840
7.

Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

Smith WW, Norton DD, Gorospe M, Jiang H, Nemoto S, Holbrook NJ, Finkel T, Kusiak JW.

J Cell Biol. 2005 Apr 25;169(2):331-9. Epub 2005 Apr 18.

8.

Singlet oxygen-induced attenuation of growth factor signaling: possible role of ceramides.

Schieke SM, von Montfort C, Buchczyk DP, Timmer A, Grether-Beck S, Krutmann J, Holbrook NJ, Klotz LO.

Free Radic Res. 2004 Jul;38(7):729-37.

PMID:
15453638
10.

Common mechanisms for declines in oxidative stress tolerance and proliferation with aging.

Li J, Holbrook NJ.

Free Radic Biol Med. 2003 Aug 1;35(3):292-9.

PMID:
12885591
11.

Effects of aging and calorie restriction of Fischer 344 rats on hepatocellular response to proliferative signals.

Ikeyama S, Kokkonen G, Martindale JL, Wang XT, Gorospe M, Holbrook NJ.

Exp Gerontol. 2003 Apr;38(4):431-9.

PMID:
12670630
12.

Caveolin-induced activation of the phosphatidylinositol 3-kinase/Akt pathway increases arsenite cytotoxicity.

Shack S, Wang XT, Kokkonen GC, Gorospe M, Longo DL, Holbrook NJ.

Mol Cell Biol. 2003 Apr;23(7):2407-14.

13.

Expression of the pro-apoptotic gene gadd153/chop is elevated in liver with aging and sensitizes cells to oxidant injury.

Ikeyama S, Wang XT, Li J, Podlutsky A, Martindale JL, Kokkonen G, van Huizen R, Gorospe M, Holbrook NJ.

J Biol Chem. 2003 May 9;278(19):16726-31. Epub 2003 Feb 27.

14.

P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling.

van Huizen R, Martindale JL, Gorospe M, Holbrook NJ.

J Biol Chem. 2003 May 2;278(18):15558-64. Epub 2003 Feb 24.

15.

Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations.

Milhavet O, Martindale JL, Camandola S, Chan SL, Gary DS, Cheng A, Holbrook NJ, Mattson MP.

J Neurochem. 2002 Nov;83(3):673-81.

16.

The Quasi-Biennial Oscillation and Ross River virus incidence in Queensland, Australia.

Done SJ, Holbrook NJ, Beggs PJ.

Int J Biometeorol. 2002 Sep;46(4):202-7. Epub 2002 Jun 25.

PMID:
12242477
17.
18.

Cellular response to oxidative stress: signaling for suicide and survival.

Martindale JL, Holbrook NJ.

J Cell Physiol. 2002 Jul;192(1):1-15. Review.

PMID:
12115731
19.

Targets of c-Jun NH(2)-terminal kinase 2-mediated tumor growth regulation revealed by serial analysis of gene expression.

Potapova O, Anisimov SV, Gorospe M, Dougherty RH, Gaarde WA, Boheler KR, Holbrook NJ.

Cancer Res. 2002 Jun 1;62(11):3257-63.

20.

Loss in oxidative stress tolerance with aging linked to reduced extracellular signal-regulated kinase and Akt kinase activities.

Ikeyama S, Kokkonen G, Shack S, Wang XT, Holbrook NJ.

FASEB J. 2002 Jan;16(1):114-6. Epub 2001 Nov 14.

PMID:
11709495
21.

Involvement of the MAP kinase pathways in induction of GADD45 following UV radiation.

Tong T, Fan W, Zhao H, Jin S, Fan F, Blanck P, Alomo I, Rajasekaran B, Liu Y, Holbrook NJ, Zhan Q.

Exp Cell Res. 2001 Sep 10;269(1):64-72.

PMID:
11525640
22.

Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence.

Wang W, Yang X, Cristofalo VJ, Holbrook NJ, Gorospe M.

Mol Cell Biol. 2001 Sep;21(17):5889-98.

23.

Protective role for c-Jun in the cellular response to DNA damage.

Potapova O, Basu S, Mercola D, Holbrook NJ.

J Biol Chem. 2001 Jul 27;276(30):28546-53. Epub 2001 May 14.

24.

Oxidative stress-induced phospholipase C-gamma 1 activation enhances cell survival.

Wang XT, McCullough KD, Wang XJ, Carpenter G, Holbrook NJ.

J Biol Chem. 2001 Jul 27;276(30):28364-71. Epub 2001 May 11.

25.

Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

Buschmann T, Potapova O, Bar-Shira A, Ivanov VN, Fuchs SY, Henderson S, Fried VA, Minamoto T, Alarcon-Vargas D, Pincus MR, Gaarde WA, Holbrook NJ, Shiloh Y, Ronai Z.

Mol Cell Biol. 2001 Apr;21(8):2743-54.

26.

UVA and singlet oxygen as inducers of cutaneous signaling events.

Klotz LO, Holbrook NJ, Sies H.

Curr Probl Dermatol. 2001;29:95-113. Review. No abstract available.

PMID:
11225205
27.

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state.

McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ.

Mol Cell Biol. 2001 Feb;21(4):1249-59.

28.

Enhanced sensitivity and long-term G2 arrest in hydrogen peroxide-treated Ku80-null cells are unrelated to DNA repair defects.

Arrington ED, Caldwell MC, Kumaravel TS, Lohani A, Joshi A, Evans MK, Chen HT, Nussenzweig A, Holbrook NJ, Gorospe M.

Free Radic Biol Med. 2000 Dec;29(11):1166-76.

PMID:
11121725
29.

Oxidants, oxidative stress and the biology of ageing.

Finkel T, Holbrook NJ.

Nature. 2000 Nov 9;408(6809):239-47. Review.

PMID:
11089981
30.

Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts.

Klotz LO, Schieke SM, Sies H, Holbrook NJ.

Biochem J. 2000 Nov 15;352 Pt 1:219-25.

31.

Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover.

Lin S, Wang W, Wilson GM, Yang X, Brewer G, Holbrook NJ, Gorospe M.

Mol Cell Biol. 2000 Nov;20(21):7903-13.

32.

Requirement for ERK activation in cisplatin-induced apoptosis.

Wang X, Martindale JL, Holbrook NJ.

J Biol Chem. 2000 Dec 15;275(50):39435-43.

33.

c-Jun N-terminal kinase is essential for growth of human T98G glioblastoma cells.

Potapova O, Gorospe M, Bost F, Dean NM, Gaarde WA, Mercola D, Holbrook NJ.

J Biol Chem. 2000 Aug 11;275(32):24767-75.

34.

Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival.

Wang X, McCullough KD, Franke TF, Holbrook NJ.

J Biol Chem. 2000 May 12;275(19):14624-31.

35.

Age-related decline in Ras/ERK mitogen-activated protein kinase cascade is linked to a reduced association between Shc and EGF receptor.

Hutter D, Yo Y, Chen W, Liu P, Holbrook NJ, Roth GS, Liu Y.

J Gerontol A Biol Sci Med Sci. 2000 Mar;55(3):B125-34.

PMID:
10795716
36.

Transforming growth factor-beta 1 suppresses serum deprivation-induced death of A549 cells through differential effects on c-Jun and JNK activities.

Huang Y, Hutter D, Liu Y, Wang X, Sheikh MS, Chan AM, Holbrook NJ.

J Biol Chem. 2000 Jun 16;275(24):18234-42.

37.

Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner.

Potapova O, Gorospe M, Dougherty RH, Dean NM, Gaarde WA, Holbrook NJ.

Mol Cell Biol. 2000 Mar;20(5):1713-22.

38.

Activation of the cholesterol pathway and Ras maturation in response to stress.

Shack S, Gorospe M, Fawcett TW, Hudgins WR, Holbrook NJ.

Oncogene. 1999 Oct 28;18(44):6021-8.

39.

gadd45 is not required for activation of c-Jun N-terminal kinase or p38 during acute stress.

Wang X, Gorospe M, Holbrook NJ.

J Biol Chem. 1999 Oct 15;274(42):29599-602.

40.

Functional role of p21 during the cellular response to stress.

Gorospe M, Wang X, Holbrook NJ.

Gene Expr. 1999;7(4-6):377-85. Review.

41.

The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract.

Sheikh MS, Huang Y, Fernandez-Salas EA, El-Deiry WS, Friess H, Amundson S, Yin J, Meltzer SJ, Holbrook NJ, Fornace AJ Jr.

Oncogene. 1999 Jul 15;18(28):4153-9.

42.
43.
45.

Protective function of von Hippel-Lindau protein against impaired protein processing in renal carcinoma cells.

Gorospe M, Egan JM, Zbar B, Lerman M, Geil L, Kuzmin I, Holbrook NJ.

Mol Cell Biol. 1999 Feb;19(2):1289-300.

46.

Age-related changes in activation of mitogen-activated protein kinase cascades by oxidative stress.

Guyton KZ, Gorospe M, Wang X, Mock YD, Kokkonen GC, Liu Y, Roth GS, Holbrook NJ.

J Investig Dermatol Symp Proc. 1998 Aug;3(1):23-7. Review.

48.
49.

Impairments in both p70 S6 kinase and extracellular signal-regulated kinase signaling pathways contribute to the decline in proliferative capacity of aged hepatocytes.

Liu Y, Gorospe M, Kokkonen GC, Boluyt MO, Younes A, Mock YD, Wang X, Roth GS, Holbrook NJ.

Exp Cell Res. 1998 Apr 10;240(1):40-8.

PMID:
9570919
50.

On the feasibility of MRI-guided focused ultrasound for local induction of gene expression.

Madio DP, van Gelderen P, DesPres D, Olson AW, de Zwart JA, Fawcett TW, Holbrook NJ, Mandel M, Moonen CT.

J Magn Reson Imaging. 1998 Jan-Feb;8(1):101-4.

PMID:
9500267

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