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Items: 41

1.

Iron sequestrant DIBI, potential alternative for nares decolonization of MRSA Staphylococcus aureus, is anti-infective and inhibitory for mupirocin resistant isolates.

Allan DS, Del Carmen Parquet M, Savage KA, Holbein BE.

Antimicrob Agents Chemother. 2020 Jan 6. pii: AAC.02353-19. doi: 10.1128/AAC.02353-19. [Epub ahead of print]

PMID:
31907189
2.

DIBI, a novel 3-hydroxypyridin-4-one chelator iron-binding polymer, inhibits breast cancer cell growth and functions as a chemosensitizer by promoting S-phase DNA damage.

Greenshields AL, Power Coombs MR, Fernando W, Holbein BE, Hoskin DW.

Biometals. 2019 Dec;32(6):909-921. doi: 10.1007/s10534-019-00222-3. Epub 2019 Oct 17.

PMID:
31624972
3.

Iron should be restricted in acute infection.

Scott CR, Holbein BE, Lehmann CD.

Front Biosci (Landmark Ed). 2020 Jan 1;25:673-682.

PMID:
31585910
4.

Potential Mechanisms of Mucin-Enhanced Acinetobacter baumannii Virulence in the Mouse Model of Intraperitoneal Infection.

Harris G, Holbein BE, Zhou H, Xu HH, Chen W.

Infect Immun. 2019 Oct 18;87(11). pii: e00591-19. doi: 10.1128/IAI.00591-19. Print 2019 Nov.

PMID:
31405959
5.

Antibiotic-Resistant Acinetobacter baumannii Is Susceptible to the Novel Iron-Sequestering Anti-infective DIBI In Vitro and in Experimental Pneumonia in Mice.

Parquet MDC, Savage KA, Allan DS, Ang MTC, Chen W, Logan SM, Holbein BE.

Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e00855-19. doi: 10.1128/AAC.00855-19. Print 2019 Sep.

PMID:
31209004
6.

Erratum for Savage et al., "Iron Restriction to Clinical Isolates of Candida albicans by the Novel Chelator DIBI Inhibits Growth and Increases Sensitivity to Azoles In Vitro and In Vivo in a Murine Model of Experimental Vaginitis".

Savage KA, Parquet MDC, Allan DS, Davidson RJ, Holbein BE, Lilly EA, Fidel PL Jr.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e02508-18. doi: 10.1128/AAC.02508-18. Print 2019 Feb. No abstract available.

7.

Selective sensitivity of the gut microbiome to iron chelators in polybacterial abdominal sepsis.

Dickson K, Liu S, Zhou J, Langille M, Holbein BE, Lehmann C.

Med Hypotheses. 2018 Nov;120:68-71. doi: 10.1016/j.mehy.2018.08.018. Epub 2018 Aug 24.

PMID:
30220344
8.

Novel Iron-Chelator DIBI Inhibits Staphylococcus aureus Growth, Suppresses Experimental MRSA Infection in Mice and Enhances the Activities of Diverse Antibiotics in vitro.

Parquet MDC, Savage KA, Allan DS, Davidson RJ, Holbein BE.

Front Microbiol. 2018 Aug 14;9:1811. doi: 10.3389/fmicb.2018.01811. eCollection 2018.

9.

DIBI, a 3-hydroxypyridin-4-one chelator iron-binding polymer with enhanced antimicrobial activity.

Ang MTC, Gumbau-Brisa R, Allan DS, McDonald R, Ferguson MJ, Holbein BE, Bierenstiel M.

Medchemcomm. 2018 Jun 18;9(7):1206-1212. doi: 10.1039/c8md00192h. eCollection 2018 Jul 1.

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11.

DIBI, a polymeric hydroxypyridinone iron chelator, reduces ocular inflammation in local and systemic endotoxin-induced uveitis.

Arora N, Caldwell A, Wafa K, Szczesniak A, Caldwell M, Al-Banna N, Sharawy N, Islam S, Zhou J, Holbein BE, Kelly MEM, Lehmann C.

Clin Hemorheol Microcirc. 2018;69(1-2):153-164. doi: 10.3233/CH-189109.

PMID:
29630535
12.

Iron chelation for the treatment of uveitis.

Chen J, Zhou J, Kelly M, Holbein BE, Lehmann C.

Med Hypotheses. 2017 Jun;103:1-4. doi: 10.1016/j.mehy.2017.03.029. Epub 2017 Mar 30.

PMID:
28571790
13.

Anti-inflammatory and anti-bacterial effects of iron chelation in experimental sepsis.

Islam S, Jarosch S, Zhou J, Parquet Mdel C, Toguri JT, Colp P, Holbein BE, Lehmann C.

J Surg Res. 2016 Jan;200(1):266-73. doi: 10.1016/j.jss.2015.07.001. Epub 2015 Jul 8.

PMID:
26235905
14.

Inhibitory effect of iron withdrawal by chelation on the growth of human and murine mammary carcinoma and fibrosarcoma cells.

Power Coombs MR, Grant T, Greenshields AL, Arsenault DJ, Holbein BE, Hoskin DW.

Exp Mol Pathol. 2015 Oct;99(2):262-70. doi: 10.1016/j.yexmp.2015.07.008. Epub 2015 Jul 22.

PMID:
26210486
15.

Quantification of total iodine in intact granular starches of different botanical origin exposed to iodine vapor at various water activities.

Manion B, Ye M, Holbein BE, Seetharaman K.

Carbohydr Res. 2011 Nov 8;346(15):2482-90. doi: 10.1016/j.carres.2011.08.017. Epub 2011 Aug 27.

PMID:
21962455
16.

A new method for quantifying iodine in a starch-iodine matrix.

Manion BA, Holbein BE, Marcone MF, Seetharaman K.

Carbohydr Res. 2010 Dec 10;345(18):2698-704. doi: 10.1016/j.carres.2010.09.025. Epub 2010 Oct 1.

PMID:
20971452
17.

Effect of trace iron levels and iron withdrawal by chelation on the growth of Candida albicans and Candida vini.

Holbein BE, Mira de Orduña R.

FEMS Microbiol Lett. 2010 Jun;307(1):19-24. doi: 10.1111/j.1574-6968.2010.01956.x. Epub 2010 Mar 19.

18.

Use of wastewater and compost extracts as nutrient sources for growing nursery and turfgrass species.

Michitsch RC, Chong C, Holbein BE, Voroney RP, Liu HW.

J Environ Qual. 2007 May 25;36(4):1031-41. Print 2007 Jul-Aug.

PMID:
17526882
19.

Using mushroom farm and anaerobic digestion wastewaters as supplemental fertilizer sources for growing container nursery stock in a closed system.

Chong C, Purvis P, Lumis G, Holbein BE, Voroney RP, Zhou H, Liu HW, Alam MZ.

Bioresour Technol. 2008 Apr;99(6):2050-60. Epub 2007 May 3.

PMID:
17481890
20.

Potential for hydrogen and methane production from biomass residues in Canada.

Levin DB, Zhu H, Beland M, Cicek N, Holbein BE.

Bioresour Technol. 2007 Feb;98(3):654-60. Epub 2006 Mar 31.

PMID:
16580198
21.
22.

Steam pressure disruption of municipal solid waste enhances anaerobic digestion kinetics and biogas yield.

Liu HW, Walter HK, Vogt GM, Vogt HS, Holbein BE.

Biotechnol Bioeng. 2002 Jan 20;77(2):121-30.

PMID:
11753918
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28.

Role of iron in Trypanosoma cruzi infection of mice.

Lalonde RG, Holbein BE.

J Clin Invest. 1984 Feb;73(2):470-6.

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Transport of Neisseria meningitidis cultures: growth-supporting media and freezing as an alternative.

White LA, Holbein BE, Spence MR.

Can J Microbiol. 1979 Feb;25(2):119-23.

PMID:
108008
40.
41.

A modified procedure for studying enzyme secretion in yeast sphaeroplasts: subcellular distribution of invertase.

Holbein BE, Forsberg CW, Kidby DK.

Can J Microbiol. 1976 Jul;22(7):989-95.

PMID:
963619

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