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Items: 1 to 50 of 643

1.

In vivo demonstration of Pseudomonas aeruginosa biofilms as independent pharmacological microcompartments.

Christophersen L, Schwartz FA, Lerche CJ, Svanekjær T, Kragh KN, Laulund AS, Thomsen K, Henneberg KÅ, Sams T, Høiby N, Moser C.

J Cyst Fibros. 2020 Feb 14. pii: S1569-1993(20)30033-3. doi: 10.1016/j.jcf.2020.01.009. [Epub ahead of print]

PMID:
32067957
2.

Lymphocyte responses to Mycobacterium tuberculosis and Mycobacterium bovis are similar between BCG-vaccinated patients with cystic fibrosis and healthy controls.

Mauch RM, Alves PCM, Levy CE, Ribeiro JD, Ribeiro AF, Høiby N, Nolasco da Silva MT.

J Cyst Fibros. 2020 Feb 12. pii: S1569-1993(20)30045-X. doi: 10.1016/j.jcf.2020.01.013. [Epub ahead of print]

PMID:
32061516
3.

Pseudomonas aeruginosa antibody response in cystic fibrosis decreases rapidly following lung transplantation.

Schwensen HF, Moser C, Perch M, Pressler T, Høiby N.

J Cyst Fibros. 2020 Feb 7. pii: S1569-1993(20)30044-8. doi: 10.1016/j.jcf.2020.01.012. [Epub ahead of print]

PMID:
32044245
4.

Antibody response against Pseudomonas aeruginosa and its relationship with immune mediators in the upper and lower airways of cystic fibrosis patients.

Mauch RM, Hentschel J, Aanaes K, Barucha A, Nolasco da Silva MT, Levy CE, Høiby N, Mainz JG.

Pediatr Pulmonol. 2020 Apr;55(4):959-967. doi: 10.1002/ppul.24671. Epub 2020 Feb 5.

PMID:
32022432
5.

Biofilms of Mycobacterium abscessus Complex Can Be Sensitized to Antibiotics by Disaggregation and Oxygenation.

Kolpen M, Jensen PØ, Qvist T, Kragh KN, Ravnholt C, Fritz BG, Johansen UR, Bjarnsholt T, Høiby N.

Antimicrob Agents Chemother. 2020 Jan 27;64(2). pii: e01212-19. doi: 10.1128/AAC.01212-19. Print 2020 Jan 27.

PMID:
31740557
6.

Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs.

Arndal E, Johansen HK, Haagensen JAJ, Bartell JA, Marvig RL, Alanin M, Aanæs K, Høiby N, Nielsen KG, Backer V, von Buchwald C.

Eur Respir J. 2020 Jan 16;55(1). pii: 1901472. doi: 10.1183/13993003.01472-2019. Print 2020 Jan. No abstract available.

PMID:
31558658
7.

Further Commentary.

Hengzhuang W, Høiby N.

Pediatr Pulmonol. 2020 Jan;55(1):23. doi: 10.1002/ppul.24514. Epub 2019 Sep 9. No abstract available.

PMID:
31496043
8.

Lack of the Major Multifunctional Catalase KatA in Pseudomonas aeruginosa Accelerates Evolution of Antibiotic Resistance in Ciprofloxacin-Treated Biofilms.

Ahmed MN, Porse A, Abdelsamad A, Sommer M, Høiby N, Ciofu O.

Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e00766-19. doi: 10.1128/AAC.00766-19. Print 2019 Oct.

9.

Editorial comment.

Moser C, Song Z, Høiby N.

APMIS. 2019 May;127(5):385. doi: 10.1111/apm.12933. No abstract available.

PMID:
31124202
10.

Synergistic effect of immunomodulatory S100A8/A9 and ciprofloxacin against Pseudomonas aeruginosa biofilm in a murine chronic wound model.

Laulund ASB, Trøstrup H, Lerche CJ, Thomsen K, Christophersen L, Calum H, Høiby N, Moser C.

Pathog Dis. 2019 May 22. pii: ftz027. doi: 10.1093/femspd/ftz027. [Epub ahead of print]

PMID:
31116394
11.

Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis.

Lerche CJ, Christophersen LJ, Goetze JP, Nielsen PR, Thomsen K, Enevold C, Høiby N, Jensen PØ, Bundgaard H, Moser C.

PLoS One. 2019 Apr 19;14(4):e0215333. doi: 10.1371/journal.pone.0215333. eCollection 2019.

12.

Antibiotic therapy as personalized medicine - general considerations and complicating factors.

Moser C, Lerche CJ, Thomsen K, Hartvig T, Schierbeck J, Jensen PØ, Ciofu O, Høiby N.

APMIS. 2019 May;127(5):361-371. doi: 10.1111/apm.12951. Review.

PMID:
30983040
13.

Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients.

Molchanova N, Wang H, Hansen PR, Høiby N, Nielsen HM, Franzyk H.

Front Microbiol. 2019 Feb 20;10:275. doi: 10.3389/fmicb.2019.00275. eCollection 2019.

14.

P. aeruginosa flow-cell biofilms are enhanced by repeated phage treatments but can be eradicated by phage-ciprofloxacin combination.

Henriksen K, Rørbo N, Rybtke ML, Martinet MG, Tolker-Nielsen T, Høiby N, Middelboe M, Ciofu O.

Pathog Dis. 2019 Mar 1;77(2). pii: ftz011. doi: 10.1093/femspd/ftz011.

PMID:
30821815
15.

Optimization of colistin dosing regimen for cystic fibrosis patients with chronic Pseudomonas aeruginosa biofilm lung infections.

Hengzhuang W, Green K, Pressler T, Skov M, Katzenstein TL, Wu X, Høiby N.

Pediatr Pulmonol. 2019 May;54(5):575-580. doi: 10.1002/ppul.24269. Epub 2019 Feb 25.

PMID:
30803159
16.

Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients.

Møller SA, Jensen PØ, Høiby N, Ciofu O, Kragh KN, Bjarnsholt T, Kolpen M.

J Cyst Fibros. 2019 Sep;18(5):657-664. doi: 10.1016/j.jcf.2019.01.005. Epub 2019 Jan 31.

PMID:
30711384
17.

Secretory IgA-mediated immune response in saliva and early detection of Pseudomonas aeruginosa in the lower airways of pediatric cystic fibrosis patients.

Mauch RM, Rossi CL, Nolasco da Silva MT, Bianchi Aiello T, Ribeiro JD, Ribeiro AF, Høiby N, Levy CE.

Med Microbiol Immunol. 2019 Apr;208(2):205-213. doi: 10.1007/s00430-019-00578-w. Epub 2019 Jan 31.

PMID:
30706137
18.

Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study.

Alanin MC, Pressler T, Aanaes K, Ekstrøm CT, Skov M, Johansen HK, Nielsen KG, von Buchwald C, Høiby N.

Health Sci Rep. 2018 Jul 12;1(8):e52. doi: 10.1002/hsr2.52. eCollection 2018 Aug.

19.

Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth.

Høiby N, Henneberg KÅ, Wang H, Stavnsbjerg C, Bjarnsholt T, Ciofu O, Johansen UR, Sams T.

Int J Antimicrob Agents. 2019 May;53(5):564-573. doi: 10.1016/j.ijantimicag.2018.12.015. Epub 2019 Jan 5.

20.

Antibody response against Mycobacterium avium complex in cystic fibrosis patients measured by a novel IgG ELISA test.

Ravnholt C, Qvist T, Kolpen M, Pressler T, Skov M, Høiby N.

J Cyst Fibros. 2019 Jul;18(4):516-521. doi: 10.1016/j.jcf.2018.11.011. Epub 2018 Nov 29.

PMID:
30503330
21.

Adaptation of Pseudomonas aeruginosa to the chronic phenotype by mutations in the algTmucABD operon in isolates from Brazilian cystic fibrosis patients.

Candido Caçador N, Paulino da Costa Capizzani C, Gomes Monteiro Marin Torres LA, Galetti R, Ciofu O, da Costa Darini AL, Høiby N.

PLoS One. 2018 Nov 29;13(11):e0208013. doi: 10.1371/journal.pone.0208013. eCollection 2018.

22.

The importance of early diagnosis of Mycobacterium abscessus complex in patients with cystic fibrosis.

Ravnholt C, Kolpen M, Skov M, Moser C, Katzenstein TL, Pressler T, Høiby N, Qvist T.

APMIS. 2018 Dec;126(12):885-891. doi: 10.1111/apm.12903. Review.

PMID:
30456869
23.

Next generation microbiology and cystic fibrosis diagnostics: are we there yet?

Moser C, Thomsen TR, Høiby N.

Curr Opin Pulm Med. 2018 Nov;24(6):599-605. doi: 10.1097/MCP.0000000000000516. Review.

PMID:
30074508
24.

Erratum: Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines-implications for delayed wound closure?

Trøstrup H, Lerche CJ, Christophersen LJ, Thomsen K, Jensen PØ, Hougen HP, Høiby N, Moser C.

Pathog Dis. 2017 Nov 30;75(8). doi: 10.1093/femspd/ftx110. No abstract available.

PMID:
30052962
25.

Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms.

Gade PAV, Olsen TB, Jensen PØ, Kolpen M, Høiby N, Henneberg KÅ, Sams T.

PLoS One. 2018 Jun 14;13(6):e0198909. doi: 10.1371/journal.pone.0198909. eCollection 2018.

26.

Evolution of Antibiotic Resistance in Biofilm and Planktonic Pseudomonas aeruginosa Populations Exposed to Subinhibitory Levels of Ciprofloxacin.

Ahmed MN, Porse A, Sommer MOA, Høiby N, Ciofu O.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00320-18. doi: 10.1128/AAC.00320-18. Print 2018 Aug.

27.

A systematic review of studies on the faecal microbiota in anorexia nervosa: future research may need to include microbiota from the small intestine.

Schwensen HF, Kan C, Treasure J, Høiby N, Sjögren M.

Eat Weight Disord. 2018 Aug;23(4):399-418. doi: 10.1007/s40519-018-0499-9. Epub 2018 Mar 14. Review.

PMID:
29542066
28.

The accessibility of topical treatment in the paranasal sinuses on operated cystic fibrosis patients assessed by scintigraphy.

Aanaes K, Alanin MC, Nielsen KG, Moller Jorgensen M, von Buchwald C, Hoiby N, Johansen HK, Johannesen HH, Mortensen J.

Rhinology. 2018 Sep 1;56(3):268-273. doi: 10.4193/Rhin17.243.

PMID:
29509830
29.

Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor.

Trøstrup H, Lerche CJ, Christophersen LJ, Thomsen K, Jensen PØ, Hougen HP, Høiby N, Moser C.

Int Wound J. 2018 Feb;15(1):123-132. doi: 10.1111/iwj.12846. Epub 2017 Nov 27.

PMID:
29178668
30.

Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis.

Mauch RM, Jensen PØ, Moser C, Levy CE, Høiby N.

J Cyst Fibros. 2018 Mar;17(2):143-152. doi: 10.1016/j.jcf.2017.08.012. Epub 2017 Oct 21. Review.

31.

IgG avidity to Pseudomonas aeruginosa over the course of chronic lung biofilm infection in cystic fibrosis.

Mauch RM, Nørregaard LL, Ciofu O, Levy CE, Høiby N.

J Cyst Fibros. 2018 May;17(3):356-359. doi: 10.1016/j.jcf.2017.09.004. Epub 2017 Oct 12.

PMID:
29032178
32.

Hyperbaric Oxygen Sensitizes Anoxic Pseudomonas aeruginosa Biofilm to Ciprofloxacin.

Kolpen M, Lerche CJ, Kragh KN, Sams T, Koren K, Jensen AS, Line L, Bjarnsholt T, Ciofu O, Moser C, Kühl M, Høiby N, Jensen PØ.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01024-17. doi: 10.1128/AAC.01024-17. Print 2017 Nov.

33.

Sinus bacteriology in patients with cystic fibrosis or primary ciliary dyskinesia: A systematic review.

Møller ME, Alanin MC, Grønhøj C, Aanæs K, Høiby N, von Buchwald C.

Am J Rhinol Allergy. 2017 Sep 1;31(5):293-298. doi: 10.2500/ajra.2017.31.4461. Review.

34.

Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds.

Trøstrup H, Lerche CJ, Christophersen L, Jensen PØ, Høiby N, Moser C.

Int J Mol Sci. 2017 Jun 26;18(7). pii: E1359. doi: 10.3390/ijms18071359.

35.

Hyperbaric oxygen therapy augments tobramycin efficacy in experimental Staphylococcus aureus endocarditis.

Lerche CJ, Christophersen LJ, Kolpen M, Nielsen PR, Trøstrup H, Thomsen K, Hyldegaard O, Bundgaard H, Jensen PØ, Høiby N, Moser C.

Int J Antimicrob Agents. 2017 Sep;50(3):406-412. doi: 10.1016/j.ijantimicag.2017.04.025. Epub 2017 Jun 29.

PMID:
28669832
36.

Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines-implications for delayed wound closure?

Trøstrup H, Lerche CJ, Christophersen LJ, Thomsen K, Jensen PØ, Hougen HP, Høiby N, Moser C.

Pathog Dis. 2017 Sep 29;75(7). doi: 10.1093/femspd/ftx068. Erratum in: Pathog Dis. 2017 Nov 30;75(8):.

PMID:
28645160
37.

Secretory IgA response against Pseudomonas aeruginosa in the upper airways and the link with chronic lung infection in cystic fibrosis.

Mauch RM, Rossi CL, Aiello TB, Ribeiro JD, Ribeiro AF, Høiby N, Levy CE.

Pathog Dis. 2017 Aug 31;75(6). doi: 10.1093/femspd/ftx069.

PMID:
28645157
38.

Mouse Model of Burn Wound and Infection: Thermal (Hot Air) Lesion-Induced Immunosuppression.

Calum H, Høiby N, Moser C.

Curr Protoc Mouse Biol. 2017 Jun 19;7(2):77-87. doi: 10.1002/cpmo.25.

PMID:
28628217
39.

Diagnosis of biofilm infections in cystic fibrosis patients.

Høiby N, Bjarnsholt T, Moser C, Jensen PØ, Kolpen M, Qvist T, Aanaes K, Pressler T, Skov M, Ciofu O.

APMIS. 2017 Apr;125(4):339-343. doi: 10.1111/apm.12689. Review.

PMID:
28407432
40.

Chronic urinary tract infections in patients with spinal cord lesions - biofilm infection with need for long-term antibiotic treatment.

Tofte N, Nielsen AC, Trøstrup H, Andersen CB, Von Linstow M, Hansen B, Biering-Sørensen F, Høiby N, Moser C.

APMIS. 2017 Apr;125(4):385-391. doi: 10.1111/apm.12685. Review.

PMID:
28407430
41.

Biofilms and host response - helpful or harmful.

Moser C, Pedersen HT, Lerche CJ, Kolpen M, Line L, Thomsen K, Høiby N, Jensen PØ.

APMIS. 2017 Apr;125(4):320-338. doi: 10.1111/apm.12674. Review.

PMID:
28407429
42.

A short history of microbial biofilms and biofilm infections.

Høiby N.

APMIS. 2017 Apr;125(4):272-275. doi: 10.1111/apm.12686. Review.

PMID:
28407426
43.

Experimental Pseudomonas aeruginosa mediated rhino sinusitis in mink.

Kirkeby S, Hammer AS, Høiby N, Salomonsen CM.

Int J Pediatr Otorhinolaryngol. 2017 May;96:156-163. doi: 10.1016/j.ijporl.2016.12.037. Epub 2016 Dec 27.

PMID:
28302328
44.

Individual pharmacokinetic variation leads to underdosing of ciprofloxacin in some cystic fibrosis patients.

Schultz AN, Høiby N, Nielsen XC, Pressler T, Dalhoff K, Duno M, Buchard A, Johansen HK, Wang H, Dalbøge CS.

Pediatr Pulmonol. 2017 Mar;52(3):319-323. doi: 10.1002/ppul.23638. Epub 2016 Nov 4.

PMID:
28221736
45.

Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia.

Alanin MC, Aanaes K, Høiby N, Pressler T, Skov M, Nielsen KG, Johansen HK, von Buchwald C.

Int Forum Allergy Rhinol. 2017 Mar;7(3):240-247. doi: 10.1002/alr.21873. Epub 2016 Nov 23.

PMID:
27879058
46.

Phenotypic shift in Pseudomonas aeruginosa populations from cystic fibrosis lungs after 2-week antipseudomonal treatment.

Fernández-Barat L, Ciofu O, Kragh KN, Pressler T, Johansen U, Motos A, Torres A, Hoiby N.

J Cyst Fibros. 2017 Mar;16(2):222-229. doi: 10.1016/j.jcf.2016.08.005. Epub 2016 Sep 17.

47.

Evaluation of a bovine antibody test for diagnosing Mycobacterium avium complex in patients with cystic fibrosis.

Qvist T, Pressler T, Katzenstein TL, Høiby N, Collins MT.

Pediatr Pulmonol. 2017 Jan;52(1):34-40. doi: 10.1002/ppul.23608. Epub 2016 Sep 20.

PMID:
27648735
48.

The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms.

Nilsson M, Rybtke M, Givskov M, Høiby N, Twetman S, Tolker-Nielsen T.

Int J Antimicrob Agents. 2016 Sep;48(3):298-304. doi: 10.1016/j.ijantimicag.2016.06.019. Epub 2016 Jul 28.

PMID:
27502751
49.

Bacterial evolution in PCD and CF patients follows the same mutational steps.

Sommer LM, Alanin MC, Marvig RL, Nielsen KG, Høiby N, von Buchwald C, Molin S, Johansen HK.

Sci Rep. 2016 Jun 28;6:28732. doi: 10.1038/srep28732.

50.

Sinus surgery postpones chronic Gram-negative lung infection: cohort study of 106 patients with cystic fibrosis.

Alanin MC, Aanaes K, Høiby N, Pressler T, Skov M, Nielsen KG, Taylor-Robinson D, Waldmann E, Krogh Johansen H, von Buchwald C.

Rhinology. 2016 Sep;54(3):206-13. doi: 10.4193/Rhin15.347.

PMID:
27116399

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