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Drug-Resistant E. coli Bacteremia Transmitted by Fecal Microbiota Transplant.

DeFilipp Z, Bloom PP, Torres Soto M, Mansour MK, Sater MRA, Huntley MH, Turbett S, Chung RT, Chen YB, Hohmann EL.

N Engl J Med. 2019 Oct 30. doi: 10.1056/NEJMoa1910437. [Epub ahead of print]


Recurrent Relatively Resistant Salmonella infantis Infection in 2 Immunocompromised Hosts Cleared With Prolonged Antibiotics and Fecal Microbiota Transplantation.

Torres Soto M, Hammond S, Elshaboury RH, Johnson J, Hohmann EL.

Open Forum Infect Dis. 2018 Dec 14;6(1):ofy334. doi: 10.1093/ofid/ofy334. eCollection 2019 Jan.


Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.

Smillie CS, Sauk J, Gevers D, Friedman J, Sung J, Youngster I, Hohmann EL, Staley C, Khoruts A, Sadowsky MJ, Allegretti JR, Smith MB, Xavier RJ, Alm EJ.

Cell Host Microbe. 2018 Feb 14;23(2):229-240.e5. doi: 10.1016/j.chom.2018.01.003.


Long-term taxonomic and functional divergence from donor bacterial strains following fecal microbiota transplantation in immunocompromised patients.

Moss EL, Falconer SB, Tkachenko E, Wang M, Systrom H, Mahabamunuge J, Relman DA, Hohmann EL, Bhatt AS.

PLoS One. 2017 Aug 21;12(8):e0182585. doi: 10.1371/journal.pone.0182585. eCollection 2017.


Ovarian Endometrioma Superinfected With Salmonella: Case Report and Review of the Literature.

Adelman MW, Johnson JH, Hohmann EL, Gandhi RT.

Open Forum Infect Dis. 2017 Apr 17;4(2):ofx048. doi: 10.1093/ofid/ofx048. eCollection 2017 Spring.


Reply to Lagier et al.

Khanna S, Button JE, Lombardo MJ, Vulic M, Henn MR, Cook DN, Pomerantz RJ, Hohmann EL.

J Infect Dis. 2017 Jan 1;215(1):162-164. doi: 10.1093/infdis/jiw490. Epub 2016 Oct 20. No abstract available.


Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection in Patients With Inflammatory Bowel Disease: A Single-Center Experience.

Chin SM, Sauk J, Mahabamunuge J, Kaplan JL, Hohmann EL, Khalili H.

Clin Gastroenterol Hepatol. 2017 Apr;15(4):597-599. doi: 10.1016/j.cgh.2016.11.028. Epub 2016 Dec 3. No abstract available.


Are Microbial Politics Local?

Hohmann EL.

Ann Intern Med. 2016 Nov 1;165(9):667-668. doi: 10.7326/M16-1784. Epub 2016 Aug 23. No abstract available. Erratum in: Ann Intern Med. 2016 Nov 1;165(9):679.


Oral, frozen fecal microbiota transplant (FMT) capsules for recurrent Clostridium difficile infection.

Youngster I, Mahabamunuge J, Systrom HK, Sauk J, Khalili H, Levin J, Kaplan JL, Hohmann EL.

BMC Med. 2016 Sep 9;14(1):134. doi: 10.1186/s12916-016-0680-9.


Implementation of Electronic Consent at a Biobank: An Opportunity for Precision Medicine Research.

Boutin NT, Mathieu K, Hoffnagle AG, Allen NL, Castro VM, Morash M, O'Rourke PP, Hohmann EL, Herring N, Bry L, Slaugenhaupt SA, Karlson EW, Weiss ST, Smoller JW.

J Pers Med. 2016 Jun 9;6(2). pii: E17. doi: 10.3390/jpm6020017.


Universality of human microbial dynamics.

Bashan A, Gibson TE, Friedman J, Carey VJ, Weiss ST, Hohmann EL, Liu YY.

Nature. 2016 Jun 9;534(7606):259-62. doi: 10.1038/nature18301.


A Novel Microbiome Therapeutic Increases Gut Microbial Diversity and Prevents Recurrent Clostridium difficile Infection.

Khanna S, Pardi DS, Kelly CR, Kraft CS, Dhere T, Henn MR, Lombardo MJ, Vulic M, Ohsumi T, Winkler J, Pindar C, McGovern BH, Pomerantz RJ, Aunins JG, Cook DN, Hohmann EL.

J Infect Dis. 2016 Jul 15;214(2):173-81. doi: 10.1093/infdis/jiv766. Epub 2016 Feb 8.


Fecal microbiota transplant: benefits and risks.

Weil AA, Hohmann EL.

Open Forum Infect Dis. 2015 Feb 4;2(1):ofv005. doi: 10.1093/ofid/ofv005. eCollection 2015 Jan. No abstract available.


Fecal microbiota transplantation for Clostridium difficile infection--reply.

Youngster I, Hohmann EL.

JAMA. 2015 Feb 17;313(7):726. doi: 10.1001/jama.2014.18619. No abstract available.


Case 25-2014: A man with ulcerative colitis and bloody diarrhea.

Hohmann EL.

N Engl J Med. 2014 Nov 6;371(19):1848-9. doi: 10.1056/NEJMc1410949. No abstract available.


Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection.

Youngster I, Russell GH, Pindar C, Ziv-Baran T, Sauk J, Hohmann EL.

JAMA. 2014 Nov 5;312(17):1772-8. doi: 10.1001/jama.2014.13875. Erratum in: JAMA. 2015 Feb 17;313(7):729.


Case Records of the Massachusetts General Hospital. Case 25-2014. A 37-year-old man with ulcerative colitis and bloody diarrhea.

Hohmann EL, Ananthakrishnan AN, Deshpande V.

N Engl J Med. 2014 Aug 14;371(7):668-75. doi: 10.1056/NEJMcpc1400842.


Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients.

Kelly CR, Ihunnah C, Fischer M, Khoruts A, Surawicz C, Afzali A, Aroniadis O, Barto A, Borody T, Giovanelli A, Gordon S, Gluck M, Hohmann EL, Kao D, Kao JY, McQuillen DP, Mellow M, Rank KM, Rao K, Ray A, Schwartz MA, Singh N, Stollman N, Suskind DL, Vindigni SM, Youngster I, Brandt L.

Am J Gastroenterol. 2014 Jul;109(7):1065-71. doi: 10.1038/ajg.2014.133. Epub 2014 Jun 3.


Fecal microbiota transplant for relapsing Clostridium difficile infection using a frozen inoculum from unrelated donors: a randomized, open-label, controlled pilot study.

Youngster I, Sauk J, Pindar C, Wilson RG, Kaplan JL, Smith MB, Alm EJ, Gevers D, Russell GH, Hohmann EL.

Clin Infect Dis. 2014 Jun;58(11):1515-22. doi: 10.1093/cid/ciu135. Epub 2014 Apr 23.


Intestinal alkaline phosphatase promotes gut bacterial growth by reducing the concentration of luminal nucleotide triphosphates.

Malo MS, Moaven O, Muhammad N, Biswas B, Alam SN, Economopoulos KP, Gul SS, Hamarneh SR, Malo NS, Teshager A, Mohamed MM, Tao Q, Narisawa S, Millán JL, Hohmann EL, Warren HS, Robson SC, Hodin RA.

Am J Physiol Gastrointest Liver Physiol. 2014 May 15;306(10):G826-38. doi: 10.1152/ajpgi.00357.2013. Epub 2014 Apr 10.


Transcutaneous immunization of healthy volunteers with an attenuated Listeria monocytogenes vaccine strain and cholera toxin adjuvant.

Eypper EH, Johnson PV, Purro EI, Hohmann EL.

Vaccine. 2013 Jul 11;31(32):3257-61. doi: 10.1016/j.vaccine.2013.05.028. Epub 2013 May 22.


Diagnosis of influenza from lower respiratory tract sampling after negative upper respiratory tract sampling.

Bogoch II, Andrews JR, Zachary KC, Hohmann EL.

Virulence. 2013 Jan 1;4(1):82-4. doi: 10.4161/viru.22466. Epub 2012 Nov 7.


Case records of the Massachusetts General Hospital. Case 8-2012. A 53-year-old man with Crohn's disease, diarrhea, fever, and bacteremia.

Hohmann EL, Kim J.

N Engl J Med. 2012 Mar 15;366(11):1039-45. doi: 10.1056/NEJMcpc1110054. No abstract available. Erratum in: N Engl J Med. 2012 May 24;366(21):2040.


In vivo expression of Salmonella enterica serotype Typhi genes in the blood of patients with typhoid fever in Bangladesh.

Sheikh A, Charles RC, Sharmeen N, Rollins SM, Harris JB, Bhuiyan MS, Arifuzzaman M, Khanam F, Bukka A, Kalsy A, Porwollik S, Leung DT, Brooks WA, LaRocque RC, Hohmann EL, Cravioto A, Logvinenko T, Calderwood SB, McClelland M, Graham JE, Qadri F, Ryan ET.

PLoS Negl Trop Dis. 2011 Dec;5(12):e1419. doi: 10.1371/journal.pntd.0001419. Epub 2011 Dec 13.


Pandemic H1N1 influenza infection in adult transplant recipients.

Bogoch II, Andrews JR, Hohmann EL, Kotton CN, Marty FM.

Transplantation. 2011 Jun 27;91(12):e80-1. doi: 10.1097/TP.0b013e31821c1eac. No abstract available.


Local peritoneal irrigation with intestinal alkaline phosphatase is protective against peritonitis in mice.

Ebrahimi F, Malo MS, Alam SN, Moss AK, Yammine H, Ramasamy S, Biswas B, Chen KT, Muhammad N, Mostafa G, Warren HS, Hohmann EL, Hodin RA.

J Gastrointest Surg. 2011 May;15(5):860-9. doi: 10.1007/s11605-010-1405-6. Epub 2011 Mar 1.


HIV-1 and 2009 H1N1 influenza A in adults.

Bogoch II, Andrews JR, Marty FM, Hohmann EL.

J Acquir Immune Defic Syndr. 2011 Apr;56(4):e111-3. doi: 10.1097/QAI.0b013e31820a9afb. No abstract available.


Attenuated Listeria monocytogenes vaccine vectors expressing influenza A nucleoprotein: preclinical evaluation and oral inoculation of volunteers.

Johnson PV, Blair BM, Zeller S, Kotton CN, Hohmann EL.

Microbiol Immunol. 2011 May;55(5):304-17. doi: 10.1111/j.1348-0421.2011.00322.x.


Analysis of Salmonella enterica serotype paratyphi A gene expression in the blood of bacteremic patients in Bangladesh.

Sheikh A, Charles RC, Rollins SM, Harris JB, Bhuiyan MS, Khanam F, Bukka A, Kalsy A, Porwollik S, Brooks WA, LaRocque RC, Hohmann EL, Cravioto A, Logvinenko T, Calderwood SB, McClelland M, Graham JE, Qadri F, Ryan ET.

PLoS Negl Trop Dis. 2010 Dec 7;4(12):e908. doi: 10.1371/journal.pntd.0000908.


Intestinal alkaline phosphatase preserves the normal homeostasis of gut microbiota.

Malo MS, Alam SN, Mostafa G, Zeller SJ, Johnson PV, Mohammad N, Chen KT, Moss AK, Ramasamy S, Faruqui A, Hodin S, Malo PS, Ebrahimi F, Biswas B, Narisawa S, Millán JL, Warren HS, Kaplan JB, Kitts CL, Hohmann EL, Hodin RA.

Gut. 2010 Nov;59(11):1476-84. doi: 10.1136/gut.2010.211706.


A role for intestinal alkaline phosphatase in the maintenance of local gut immunity.

Chen KT, Malo MS, Beasley-Topliffe LK, Poelstra K, Millan JL, Mostafa G, Alam SN, Ramasamy S, Warren HS, Hohmann EL, Hodin RA.

Dig Dis Sci. 2011 Apr;56(4):1020-7. doi: 10.1007/s10620-010-1396-x. Epub 2010 Sep 16.


Intestinal alkaline phosphatase has beneficial effects in mouse models of chronic colitis.

Ramasamy S, Nguyen DD, Eston MA, Alam SN, Moss AK, Ebrahimi F, Biswas B, Mostafa G, Chen KT, Kaliannan K, Yammine H, Narisawa S, Millán JL, Warren HS, Hohmann EL, Mizoguchi E, Reinecker HC, Bhan AK, Snapper SB, Malo MS, Hodin RA.

Inflamm Bowel Dis. 2011 Feb;17(2):532-42. doi: 10.1002/ibd.21377.


Identification of specific targets for the gut mucosal defense factor intestinal alkaline phosphatase.

Chen KT, Malo MS, Moss AK, Zeller S, Johnson P, Ebrahimi F, Mostafa G, Alam SN, Ramasamy S, Warren HS, Hohmann EL, Hodin RA.

Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G467-75. doi: 10.1152/ajpgi.00364.2009. Epub 2010 May 20.


The International LAM Registry: a component of an innovative web-based clinician, researcher, and patient-driven rare disease research platform.

Nurok M, Eslick I, Carvalho CR, Costabel U, D'Armiento J, Glanville AR, Harari S, Henske EP, Inoue Y, Johnson SR, Lacronique J, Lazor R, Moss J, Ruoss SJ, Ryu JH, Seyama K, Watz H, Xu KF, Hohmann EL, Moss F.

Lymphat Res Biol. 2010 Mar;8(1):81-7. doi: 10.1089/lrb.2009.0028.


Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium.

Charles RC, Harris JB, Chase MR, Lebrun LM, Sheikh A, LaRocque RC, Logvinenko T, Rollins SM, Tarique A, Hohmann EL, Rosenberg I, Krastins B, Sarracino DA, Qadri F, Calderwood SB, Ryan ET.

PLoS One. 2009 Sep 10;4(9):e6994. doi: 10.1371/journal.pone.0006994.


Gene therapy--still a work in clinical and regulatory progress.

Hohmann EL.

N Engl J Med. 2009 Jul 9;361(2):193-5. doi: 10.1056/NEJMe0902716. No abstract available.


Killed but metabolically active Salmonella typhimurium: application of a new technology to an old vector.

Lankowski AJ, Hohmann EL.

J Infect Dis. 2007 Apr 15;195(8):1203-11. Epub 2007 Mar 5.


Safety and immunogenicity of attenuated Salmonella enterica serovar Typhimurium delivering an HIV-1 Gag antigen via the Salmonella Type III secretion system.

Kotton CN, Lankowski AJ, Scott N, Sisul D, Chen LM, Raschke K, Borders G, Boaz M, Spentzou A, Galán JE, Hohmann EL.

Vaccine. 2006 Sep 11;24(37-39):6216-24. Epub 2006 Jun 13.


Comparison of rectal swabs with fecal cultures for detection of Salmonella typhimurium in adult volunteers.

Kotton CN, Lankowski AJ, Hohmann EL.

Diagn Microbiol Infect Dis. 2006 Oct;56(2):123-6. Epub 2006 May 24.


Enteric pathogens as vaccine vectors for foreign antigen delivery.

Kotton CN, Hohmann EL.

Infect Immun. 2004 Oct;72(10):5535-47. Review. No abstract available.


Listeriosis during pregnancy: a case series and review of 222 cases.

Mylonakis E, Paliou M, Hohmann EL, Calderwood SB, Wing EJ.

Medicine (Baltimore). 2002 Jul;81(4):260-9. Review. No abstract available.


Nontyphoidal salmonellosis.

Hohmann EL.

Clin Infect Dis. 2001 Jan 15;32(2):263-9. Epub 2001 Jan 15. Review.


Safety and immunogenicity of phoP/phoQ-deleted Salmonella typhi expressing Helicobacter pylori urease in adult volunteers.

DiPetrillo MD, Tibbetts T, Kleanthous H, Killeen KP, Hohmann EL.

Vaccine. 1999 Oct 14;18(5-6):449-59.


Regulation of host immune responses by modification of Salmonella virulence genes.

VanCott JL, Chatfield SN, Roberts M, Hone DM, Hohmann EL, Pascual DW, Yamamoto M, Kiyono H, McGhee JR.

Nat Med. 1998 Nov;4(11):1247-52.


phoP/phoQ-deleted Salmonella typhi (Ty800) is a safe and immunogenic single-dose typhoid fever vaccine in volunteers.

Hohmann EL, Oletta CA, Killeen KP, Miller SI.

J Infect Dis. 1996 Jun;173(6):1408-14.


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