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Items: 1 to 50 of 495

1.

Sildenafil Prevents Marfan-Associated Emphysema and Early Pulmonary Artery Dilation in Mice.

White Z, Milad N, Tehrani AY, Lamothe J, Hogg JC, Esfandiarei M, Seidman M, Booth S, Hackett TL, Morissette MC, Bernatchez P.

Am J Pathol. 2019 Aug;189(8):1536-1546. doi: 10.1016/j.ajpath.2019.05.003. Epub 2019 May 22.

PMID:
31125551
2.

Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease.

Tam A, Hughes M, McNagny KM, Obeidat M, Hackett TL, Leung JM, Shaipanich T, Dorscheid DR, Singhera GK, Yang CWT, Paré PD, Hogg JC, Nickle D, Sin DD.

Sci Rep. 2019 Mar 4;9(1):3353. doi: 10.1038/s41598-019-40045-3.

3.

Non-Invasive Imaging Biomarker Identifies Small Airway Damage in Severe COPD.

Vasilescu DM, Martinez FJ, Marchetti N, Galbán CJ, Hatt C, Meldrum CA, Dass C, Tanabe N, Reddy RM, Lagstein A, Ross BD, Labaki WW, Murray S, Xia M, Curtis JL, Hackett TL, Kazerooni EA, Criner GJ, Hogg JC, Han MK.

Am J Respir Crit Care Med. 2019 Feb 22. doi: 10.1164/rccm.201811-2083OC. [Epub ahead of print]

PMID:
30794432
4.

Gene correlation network analysis to identify regulatory factors in idiopathic pulmonary fibrosis.

McDonough JE, Kaminski N, Thienpont B, Hogg JC, Vanaudenaerde BM, Wuyts WA.

Thorax. 2019 Feb;74(2):132-140. doi: 10.1136/thoraxjnl-2018-211929. Epub 2018 Oct 26.

5.

Reply to Hu et al.: How to Determine the Patient's Head and Neck Posture during Computed Tomography Scanning?

Kirby M, Tan WC, Hogg JC, Coxson HO.

Am J Respir Crit Care Med. 2018 Nov 1;198(9):1238-1239. doi: 10.1164/rccm.201806-1154LE. No abstract available.

PMID:
30118318
6.

Small airways disease in mild and moderate chronic obstructive pulmonary disease: a cross-sectional study.

Koo HK, Vasilescu DM, Booth S, Hsieh A, Katsamenis OL, Fishbane N, Elliott WM, Kirby M, Lackie P, Sinclair I, Warner JA, Cooper JD, Coxson HO, Paré PD, Hogg JC, Hackett TL.

Lancet Respir Med. 2018 Aug;6(8):591-602. doi: 10.1016/S2213-2600(18)30196-6. Epub 2018 Jul 4.

PMID:
30072106
7.

A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis.

McDonough JE, Martens DS, Tanabe N, Ahangari F, Verleden SE, Maes K, Verleden GM, Kaminski N, Hogg JC, Nawrot TS, Wuyts WA, Vanaudenaerde BM.

Respir Res. 2018 Jul 9;19(1):132. doi: 10.1186/s12931-018-0838-4.

8.

The aging lung: tissue telomere shortening in health and disease.

Everaerts S, Lammertyn EJ, Martens DS, De Sadeleer LJ, Maes K, van Batenburg AA, Goldschmeding R, van Moorsel CHM, Dupont LJ, Wuyts WA, Vos R, Gayan-Ramirez G, Kaminski N, Hogg JC, Janssens W, Verleden GM, Nawrot TS, Verleden SE, McDonough JE, Vanaudenaerde BM.

Respir Res. 2018 May 11;19(1):95. doi: 10.1186/s12931-018-0794-z.

9.

Simulation of Airflow in an Idealized Emphysematous Human Acinus.

Dutta A, Vasilescu D, Hogg JC, Phillion AB, Brinkerhoff JR.

J Biomech Eng. 2018 Mar 21. doi: 10.1115/1.4039680. [Epub ahead of print]

PMID:
29570757
10.

Structure and Function Relationships in Diseases of the Small Airways.

Hogg JC, Hackett TL.

Ann Am Thorac Soc. 2018 Feb;15(Suppl 1):S18-S25. doi: 10.1513/AnnalsATS.201710-809KV. Erratum in: Ann Am Thorac Soc. 2018 Jun;15(6):768.

PMID:
29461883
11.

Analysis of airway pathology in COPD using a combination of computed tomography, micro-computed tomography and histology.

Tanabe N, Vasilescu DM, Kirby M, Coxson HO, Verleden SE, Vanaudenaerde BM, Kinose D, Nakano Y, Paré PD, Hogg JC.

Eur Respir J. 2018 Feb 14;51(2). pii: 1701245. doi: 10.1183/13993003.01245-2017. Print 2018 Feb.

12.

Inhibition of Marfan Syndrome Aortic Root Dilation by Losartan: Role of Angiotensin II Receptor Type 1-Independent Activation of Endothelial Function.

Sellers SL, Milad N, Chan R, Mielnik M, Jermilova U, Huang PL, de Crom R, Hirota JA, Hogg JC, Sandor GG, Van Breemen C, Esfandiarei M, Seidman MA, Bernatchez P.

Am J Pathol. 2018 Mar;188(3):574-585. doi: 10.1016/j.ajpath.2017.11.006.

PMID:
29433732
13.

Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population-based Study.

Kirby M, Tanabe N, Tan WC, Zhou G, Obeidat M, Hague CJ, Leipsic J, Bourbeau J, Sin DD, Hogg JC, Coxson HO; CanCOLD Collaborative Research Group; Canadian Respiratory Research Network; CanCOLD Collaborative Research Group, the Canadian Respiratory Research Network.

Am J Respir Crit Care Med. 2018 Jan 1;197(1):56-65. doi: 10.1164/rccm.201704-0692OC.

PMID:
28886252
14.

A Novel Method of Estimating Small Airway Disease Using Inspiratory-to-Expiratory Computed Tomography.

Kirby M, Yin Y, Tschirren J, Tan WC, Leipsic J, Hague CJ, Bourbeau J, Sin DD, Hogg JC, Coxson HO; CanCOLD Collaborative Research Group and the Canadian Respiratory Research Network.

Respiration. 2017;94(4):336-345. doi: 10.1159/000478865. Epub 2017 Aug 23.

15.

The cellular and molecular determinants of emphysematous destruction in COPD.

Suzuki M, Sze MA, Campbell JD, Brothers JF 2nd, Lenburg ME, McDonough JE, Elliott WM, Cooper JD, Spira A, Hogg JC.

Sci Rep. 2017 Aug 25;7(1):9562. doi: 10.1038/s41598-017-10126-2.

16.

The Role of Chest Computed Tomography in the Evaluation and Management of the Patient with Chronic Obstructive Pulmonary Disease.

Labaki WW, Martinez CH, Martinez FJ, Galbán CJ, Ross BD, Washko GR, Barr RG, Regan EA, Coxson HO, Hoffman EA, Newell JD Jr, Curran-Everett D, Hogg JC, Crapo JD, Lynch DA, Kazerooni EA, Han MK.

Am J Respir Crit Care Med. 2017 Dec 1;196(11):1372-1379. doi: 10.1164/rccm.201703-0451PP. Review. No abstract available.

17.

Surfactant protein-D deficiency suppresses systemic inflammation and reduces atherosclerosis in ApoE knockout mice.

Hirano Y, Choi A, Tsuruta M, Jaw JE, Oh Y, Ngan D, Moritani K, Chen YR, Tam S, Li Y, Vasilescu DM, Hogg JC, Francis G, Bernatchez P, Man SP, Sin DD.

Cardiovasc Res. 2017 Aug 1;113(10):1208-1218. doi: 10.1093/cvr/cvx067.

PMID:
28472244
18.

Integrative Genomics of Emphysema-Associated Genes Reveals Potential Disease Biomarkers.

Obeidat M, Nie Y, Fishbane N, Li X, Bossé Y, Joubert P, Nickle DC, Hao K, Postma DS, Timens W, Sze MA, Shannon CP, Hollander Z, Ng RT, McManus B, Miller BE, Rennard S, Spira A, Hackett TL, Lam W, Lam S, Faner R, Agusti A, Hogg JC, Sin DD, Paré PD.

Am J Respir Cell Mol Biol. 2017 Oct;57(4):411-418. doi: 10.1165/rcmb.2016-0284OC.

19.

The Contribution of Small Airway Obstruction to the Pathogenesis of Chronic Obstructive Pulmonary Disease.

Hogg JC, Paré PD, Hackett TL.

Physiol Rev. 2017 Apr;97(2):529-552. doi: 10.1152/physrev.00025.2015. Review. Erratum in: Physiol Rev. 2018 Jul 1;98(3):1909.

20.

Findings on Thoracic Computed Tomography Scans and Respiratory Outcomes in Persons with and without Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study.

Tan WC, Hague CJ, Leipsic J, Bourbeau J, Zheng L, Li PZ, Sin DD, Coxson HO, Kirby M, Hogg JC, Raju R, Road J, O'Donnell DE, Maltais F, Hernandez P, Cowie R, Chapman KR, Marciniuk DD, FitzGerald JM, Aaron SD; Canadian Respiratory Research Network and the CanCOLD Collaborative Research group.

PLoS One. 2016 Nov 18;11(11):e0166745. doi: 10.1371/journal.pone.0166745. eCollection 2016.

21.

Nondestructive cryomicro-CT imaging enables structural and molecular analysis of human lung tissue.

Vasilescu DM, Phillion AB, Tanabe N, Kinose D, Paige DF, Kantrowitz JJ, Liu G, Liu H, Fishbane N, Verleden SE, Vanaudenaerde BM, Lenburg M, Stevenson CS, Spira A, Cooper JD, Hackett TL, Hogg JC.

J Appl Physiol (1985). 2017 Jan 1;122(1):161-169. doi: 10.1152/japplphysiol.00838.2016. Epub 2016 Nov 17.

22.

Thin-Section CT Features of Idiopathic Pulmonary Fibrosis Correlated with Micro-CT and Histologic Analysis.

Mai C, Verleden SE, McDonough JE, Willems S, De Wever W, Coolen J, Dubbeldam A, Van Raemdonck DE, Verbeken EK, Verleden GM, Hogg JC, Vanaudenaerde BM, Wuyts WA, Verschakelen JA.

Radiology. 2017 Apr;283(1):252-263. doi: 10.1148/radiol.2016152362. Epub 2016 Oct 6.

23.

Micro-Computed Tomography Comparison of Preterminal Bronchioles in Centrilobular and Panlobular Emphysema.

Tanabe N, Vasilescu DM, McDonough JE, Kinose D, Suzuki M, Cooper JD, Paré PD, Hogg JC.

Am J Respir Crit Care Med. 2017 Mar 1;195(5):630-638. doi: 10.1164/rccm.201602-0278OC.

24.

Airflow obstruction is associated with increased smooth muscle extracellular matrix.

Jones RL, Noble PB, Elliot JG, Mitchell HW, McFawn PK, Hogg JC, James AL.

Eur Respir J. 2016 Jun;47(6):1855-7. doi: 10.1183/13993003.01709-2015. Epub 2016 Mar 17. No abstract available.

25.

Association between Functional Small Airway Disease and FEV1 Decline in Chronic Obstructive Pulmonary Disease.

Bhatt SP, Soler X, Wang X, Murray S, Anzueto AR, Beaty TH, Boriek AM, Casaburi R, Criner GJ, Diaz AA, Dransfield MT, Curran-Everett D, Galbán CJ, Hoffman EA, Hogg JC, Kazerooni EA, Kim V, Kinney GL, Lagstein A, Lynch DA, Make BJ, Martinez FJ, Ramsdell JW, Reddy R, Ross BD, Rossiter HB, Steiner RM, Strand MJ, van Beek EJ, Wan ES, Washko GR, Wells JM, Wendt CH, Wise RA, Silverman EK, Crapo JD, Bowler RP, Han MK; COPDGene Investigators.

Am J Respir Crit Care Med. 2016 Jul 15;194(2):178-84. doi: 10.1164/rccm.201511-2219OC.

26.

Morphometric Analysis of Explant Lungs in Cystic Fibrosis.

Boon M, Verleden SE, Bosch B, Lammertyn EJ, McDonough JE, Mai C, Verschakelen J, Kemner-van de Corput M, Tiddens HA, Proesmans M, Vermeulen FL, Verbeken EK, Cooper J, Van Raemdonck DE, Decramer M, Verleden GM, Hogg JC, Dupont LJ, Vanaudenaerde BM, De Boeck K.

Am J Respir Crit Care Med. 2016 Mar 1;193(5):516-26. doi: 10.1164/rccm.201507-1281OC.

PMID:
26551917
27.

Reply: the lung immune response to bacteria in chronic obstructive pulmonary disease.

Sze MA, Hogg JC.

Am J Respir Crit Care Med. 2015 Oct 1;192(7):903-4. doi: 10.1164/rccm.201506-1257LE. No abstract available.

PMID:
26426790
28.

Molecular mechanisms underlying variations in lung function: a systems genetics analysis.

Obeidat M, Hao K, Bossé Y, Nickle DC, Nie Y, Postma DS, Laviolette M, Sandford AJ, Daley DD, Hogg JC, Elliott WM, Fishbane N, Timens W, Hysi PG, Kaprio J, Wilson JF, Hui J, Rawal R, Schulz H, Stubbe B, Hayward C, Polasek O, Järvelin MR, Zhao JH, Jarvis D, Kähönen M, Franceschini N, North KE, Loth DW, Brusselle GG, Smith AV, Gudnason V, Bartz TM, Wilk JB, O'Connor GT, Cassano PA, Tang W, Wain LV, Soler Artigas M, Gharib SA, Strachan DP, Sin DD, Tobin MD, London SJ, Hall IP, Paré PD.

Lancet Respir Med. 2015 Oct;3(10):782-95. doi: 10.1016/S2213-2600(15)00380-X. Epub 2015 Sep 21. Erratum in: Lancet Respir Med. 2015 Dec;3(12):e44.

29.

Linking clinical phenotypes of chronic lung allograft dysfunction to changes in lung structure.

Verleden SE, Vasilescu DM, McDonough JE, Ruttens D, Vos R, Vandermeulen E, Bellon H, Geenens R, Verbeken EK, Verschakelen J, Van Raemdonck DE, Wuyts WA, Sokolow Y, Knoop C, Cooper JD, Hogg JC, Verleden GM, Vanaudenaerde BM.

Eur Respir J. 2015 Nov;46(5):1430-9. doi: 10.1183/09031936.00010615. Epub 2015 Jun 25.

30.

Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study.

Tan WC, Sin DD, Bourbeau J, Hernandez P, Chapman KR, Cowie R, FitzGerald JM, Marciniuk DD, Maltais F, Buist AS, Road J, Hogg JC, Kirby M, Coxson H, Hague C, Leipsic J, O'Donnell DE, Aaron SD; CanCOLD Collaborative Research Group.

Thorax. 2015 Sep;70(9):822-9. doi: 10.1136/thoraxjnl-2015-206938. Epub 2015 Jun 5.

PMID:
26048404
31.

Three dimensional imaging of paraffin embedded human lung tissue samples by micro-computed tomography.

Scott AE, Vasilescu DM, Seal KA, Keyes SD, Mavrogordato MN, Hogg JC, Sinclair I, Warner JA, Hackett TL, Lackie PM.

PLoS One. 2015 Jun 1;10(6):e0126230. doi: 10.1371/journal.pone.0126230. eCollection 2015.

32.

CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society.

Lynch DA, Austin JH, Hogg JC, Grenier PA, Kauczor HU, Bankier AA, Barr RG, Colby TV, Galvin JR, Gevenois PA, Coxson HO, Hoffman EA, Newell JD Jr, Pistolesi M, Silverman EK, Crapo JD.

Radiology. 2015 Oct;277(1):192-205. doi: 10.1148/radiol.2015141579. Epub 2015 May 11.

33.

Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease.

Sze MA, Dimitriu PA, Suzuki M, McDonough JE, Campbell JD, Brothers JF, Erb-Downward JR, Huffnagle GB, Hayashi S, Elliott WM, Cooper J, Sin DD, Lenburg ME, Spira A, Mohn WW, Hogg JC.

Am J Respir Crit Care Med. 2015 Aug 15;192(4):438-45. doi: 10.1164/rccm.201502-0223OC.

34.

Regional differences in alveolar density in the human lung are related to lung height.

McDonough JE, Knudsen L, Wright AC, Elliott W, Ochs M, Hogg JC.

J Appl Physiol (1985). 2015 Jun 1;118(11):1429-34.

35.

Loss of GD1-positive Lactobacillus correlates with inflammation in human lungs with COPD.

Sze MA, Utokaparch S, Elliott WM, Hogg JC, Hegele RG.

BMJ Open. 2015 Feb 4;5(2):e006677. doi: 10.1136/bmjopen-2014-006677.

36.

Genes related to emphysema are enriched for ubiquitination pathways.

Stepaniants S, Wang IM, Boie Y, Mortimer J, Kennedy B, Elliott M, Hayashi S, Luo H, Wong J, Loy L, Coulter S, Roberts CJ, Hogg JC, Sin DD, O'Neill G, Crackower M, Morris M, Paré PD, Obeidat M.

BMC Pulm Med. 2014 Nov 29;14:187. doi: 10.1186/1471-2466-14-187.

37.

Changes in the bacterial microbiota in gut, blood, and lungs following acute LPS instillation into mice lungs.

Sze MA, Tsuruta M, Yang SW, Oh Y, Man SF, Hogg JC, Sin DD.

PLoS One. 2014 Oct 21;9(10):e111228. doi: 10.1371/journal.pone.0111228. eCollection 2014.

38.

A comparison between droplet digital and quantitative PCR in the analysis of bacterial 16S load in lung tissue samples from control and COPD GOLD 2.

Sze MA, Abbasi M, Hogg JC, Sin DD.

PLoS One. 2014 Oct 16;9(10):e110351. doi: 10.1371/journal.pone.0110351. eCollection 2014.

39.

Susceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung.

Nguyen JD, Lamontagne M, Couture C, Conti M, Paré PD, Sin DD, Hogg JC, Nickle D, Postma DS, Timens W, Laviolette M, Bossé Y.

Carcinogenesis. 2014 Dec;35(12):2653-9. doi: 10.1093/carcin/bgu184. Epub 2014 Sep 3.

40.

Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction.

Lamontagne M, Timens W, Hao K, Bossé Y, Laviolette M, Steiling K, Campbell JD, Couture C, Conti M, Sherwood K, Hogg JC, Brandsma CA, van den Berge M, Sandford A, Lam S, Lenburg ME, Spira A, Paré PD, Nickle D, Sin DD, Postma DS.

Thorax. 2014 Nov;69(11):997-1004. doi: 10.1136/thoraxjnl-2014-205630. Epub 2014 Sep 2.

PMID:
25182044
41.
42.

Impact of cigarette smoke on the human and mouse lungs: a gene-expression comparison study.

Morissette MC, Lamontagne M, Bérubé JC, Gaschler G, Williams A, Yauk C, Couture C, Laviolette M, Hogg JC, Timens W, Halappanavar S, Stampfli MR, Bossé Y.

PLoS One. 2014 Mar 24;9(3):e92498. doi: 10.1371/journal.pone.0092498. eCollection 2014.

43.

Bacterial microbiome of lungs in COPD.

Sze MA, Hogg JC, Sin DD.

Int J Chron Obstruct Pulmon Dis. 2014 Feb 21;9:229-38. doi: 10.2147/COPD.S38932. eCollection 2014. Review.

44.

miR-638 regulates gene expression networks associated with emphysematous lung destruction.

Christenson SA, Brandsma CA, Campbell JD, Knight DA, Pechkovsky DV, Hogg JC, Timens W, Postma DS, Lenburg M, Spira A.

Genome Med. 2013 Dec 31;5(12):114. doi: 10.1186/gm519. eCollection 2013.

45.

The site and nature of airway obstruction after lung transplantation.

Verleden SE, Vasilescu DM, Willems S, Ruttens D, Vos R, Vandermeulen E, Hostens J, McDonough JE, Verbeken EK, Verschakelen J, Van Raemdonck DE, Rondelet B, Knoop C, Decramer M, Cooper J, Hogg JC, Verleden GM, Vanaudenaerde BM.

Am J Respir Crit Care Med. 2014 Feb 1;189(3):292-300. doi: 10.1164/rccm.201310-1894OC.

PMID:
24354907
46.

Respiratory viral detection and small airway inflammation in lung tissue of patients with stable, mild COPD.

Utokaparch S, Sze MA, Gosselink JV, McDonough JE, Elliott WM, Hogg JC, Hegele RG.

COPD. 2014 Apr;11(2):197-203. doi: 10.3109/15412555.2013.836166. Epub 2013 Oct 2.

PMID:
24088037
47.

Refining susceptibility loci of chronic obstructive pulmonary disease with lung eqtls.

Lamontagne M, Couture C, Postma DS, Timens W, Sin DD, Paré PD, Hogg JC, Nickle D, Laviolette M, Bossé Y.

PLoS One. 2013 Jul 30;8(7):e70220. doi: 10.1371/journal.pone.0070220. Print 2013.

48.

Small airway obstruction in COPD: new insights based on micro-CT imaging and MRI imaging.

Hogg JC, McDonough JE, Suzuki M.

Chest. 2013 May;143(5):1436-1443. doi: 10.1378/chest.12-1766. Review.

49.

Isoflurane regulates atypical type-A γ-aminobutyric acid receptors in alveolar type II epithelial cells.

Xiang YY, Chen X, Li J, Wang S, Faclier G, Macdonald JF, Hogg JC, Orser BA, Lu WY.

Anesthesiology. 2013 May;118(5):1065-75. doi: 10.1097/ALN.0b013e31828e180e.

PMID:
23485993
50.

A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment.

Steiling K, van den Berge M, Hijazi K, Florido R, Campbell J, Liu G, Xiao J, Zhang X, Duclos G, Drizik E, Si H, Perdomo C, Dumont C, Coxson HO, Alekseyev YO, Sin D, Pare P, Hogg JC, McWilliams A, Hiemstra PS, Sterk PJ, Timens W, Chang JT, Sebastiani P, O'Connor GT, Bild AH, Postma DS, Lam S, Spira A, Lenburg ME.

Am J Respir Crit Care Med. 2013 May 1;187(9):933-42. doi: 10.1164/rccm.201208-1449OC.

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