Sort by
Items per page

Send to

Choose Destination

Search results

Items: 17


Role of receptor occupancy assays by flow cytometry in drug development.

Stewart JJ, Green CL, Jones N, Liang M, Xu Y, Wilkins DE, Moulard M, Czechowska K, Lanham D, McCloskey TW, Ferbas J, van der Strate BW, Högerkorp CM, Wyant T, Lackey A, Litwin V.

Cytometry B Clin Cytom. 2016 Mar;90(2):110-6. doi: 10.1002/cyto.b.21355. Epub 2016 Feb 16. Review.


Recommendations for the development and validation of flow cytometry-based receptor occupancy assays.

Green CL, Stewart JJ, Högerkorp CM, Lackey A, Jones N, Liang M, Xu Y, Ferbas J, Moulard M, Czechowska K, Mc Closkey TW, van der Strate BW, Wilkins DE, Lanham D, Wyant T, Litwin V.

Cytometry B Clin Cytom. 2016 Mar;90(2):141-9. doi: 10.1002/cyto.b.21339. Epub 2016 Feb 22. Review.


A weighted method for estimation of receptor occupancy for pharmacodynamic measurements in drug development.

Sternebring O, Alifrangis L, Christensen TF, Ji H, Hegelund AC, Högerkorp CM.

Cytometry B Clin Cytom. 2016 Mar;90(2):220-9. doi: 10.1002/cyto.b.21277. Epub 2015 Aug 31.


Validation of a flow cytometry-based assay to assess C5aR receptor occupancy on neutrophils and monocytes for use in drug development.

Quadrini KJ, Hegelund AC, Cortes KE, Xue C, Kennelly SM, Ji H, Högerkorp CM, Mc Closkey TW.

Cytometry B Clin Cytom. 2016 Mar;90(2):177-90. doi: 10.1002/cyto.b.21260. Epub 2015 Sep 17.


CD14(hi)HLA-DR(dim) macrophages, with a resemblance to classical blood monocytes, dominate inflamed mucosa in Crohn's disease.

Thiesen S, Janciauskiene S, Uronen-Hansson H, Agace W, Högerkorp CM, Spee P, Håkansson K, Grip O.

J Leukoc Biol. 2014 Mar;95(3):531-41. doi: 10.1189/jlb.0113021. Epub 2013 Nov 8.


HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins.

Li Y, O'Dell S, Wilson R, Wu X, Schmidt SD, Hogerkorp CM, Louder MK, Longo NS, Poulsen C, Guenaga J, Chakrabarti BK, Doria-Rose N, Roederer M, Connors M, Mascola JR, Wyatt RT.

J Virol. 2012 Oct;86(20):11231-41. Epub 2012 Aug 8.


The simian immunodeficiency virus targets central cell cycle functions through transcriptional repression in vivo.

Hogerkorp CM, Nishimura Y, Song K, Martin MA, Roederer M.

PLoS One. 2011;6(10):e25684. doi: 10.1371/journal.pone.0025684. Epub 2011 Oct 17.


Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1.

Wu X, Yang ZY, Li Y, Hogerkorp CM, Schief WR, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, Longo NS, McKee K, O'Dell S, Louder MK, Wycuff DL, Feng Y, Nason M, Doria-Rose N, Connors M, Kwong PD, Roederer M, Wyatt RT, Nabel GJ, Mascola JR.

Science. 2010 Aug 13;329(5993):856-61. doi: 10.1126/science.1187659. Epub 2010 Jul 8.


Identification of uniquely expressed transcription factors in highly purified B-cell lymphoma samples.

Andréasson U, Edén P, Peterson C, Högerkorp CM, Jerkeman M, Andersen N, Berglund M, Sundström C, Rosenquist R, Borrebaeck CA, Ek S.

Am J Hematol. 2010 Jun;85(6):418-25. doi: 10.1002/ajh.21701.


A chromatic explosion: the development and future of multiparameter flow cytometry.

Chattopadhyay PK, Hogerkorp CM, Roederer M.

Immunology. 2008 Dec;125(4):441-9. doi: 10.1111/j.1365-2567.2008.02989.x. Review.


B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.

Forsell MN, Dey B, Mörner A, Svehla K, O'dell S, Högerkorp CM, Voss G, Thorstensson R, Shaw GM, Mascola JR, Karlsson Hedestam GB, Wyatt RT.

PLoS Pathog. 2008 Oct 3;4(10):e1000171. doi: 10.1371/journal.ppat.1000171.


Phenotypic protein profiling of different B cell sub-populations using antibody CD-microarrays.

Ellmark P, Högerkorp CM, Ek S, Belov L, Berglund M, Rosenquist R, Christopherson RI, Borrebaeck CA.

Cancer Lett. 2008 Jun 28;265(1):98-106. doi: 10.1016/j.canlet.2008.02.006. Epub 2008 Mar 18.


The human CD77- B cell population represents a heterogeneous subset of cells comprising centroblasts, centrocytes, and plasmablasts, prompting phenotypical revision.

Högerkorp CM, Borrebaeck CA.

J Immunol. 2006 Oct 1;177(7):4341-9. Erratum in: J Immunol. 2006 Dec 15;177(12):8877.


Mantle cell lymphomas acquire increased expression of CCL4, CCL5 and 4-1BB-L implicated in cell survival.

Ek S, Björck E, Högerkorp CM, Nordenskjöld M, Porwit-MacDonald A, Borrebaeck CA.

Int J Cancer. 2006 Apr 15;118(8):2092-7.


CD44-stimulated human B cells express transcripts specifically involved in immunomodulation and inflammation as analyzed by DNA microarrays.

Högerkorp CM, Bilke S, Breslin T, Ingvarsson S, Borrebaeck CA.

Blood. 2003 Mar 15;101(6):2307-13. Epub 2002 Oct 31.


Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation.

Bryder D, Ramsfjell V, Dybedal I, Theilgaard-Mönch K, Högerkorp CM, Adolfsson J, Borge OJ, Jacobsen SE.

J Exp Med. 2001 Oct 1;194(7):941-52.

Supplemental Content

Loading ...
Support Center