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The molecular pathology of eye tumors: A 2019 update Main interests for routine clinical practice.

Nahon-Esteve S, Martel A, Maschi C, Caujolle JP, Baillif S, Lassalle S, Hofman P.

Curr Mol Med. 2019 Jul 26. doi: 10.2174/1566524019666190726161044. [Epub ahead of print]


The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress.

Moreno Leon L, Gautier M, Allan R, Ilié M, Nottet N, Pons N, Paquet A, Lebrigand K, Truchi M, Fassy J, Magnone V, Kinnebrew G, Radovich M, Cheok MH, Barbry P, Vassaux G, Marquette CH, Ponzio G, Ivan M, Pottier N, Hofman P, Mari B, Rezzonico R.

Oncogene. 2019 Aug 15. doi: 10.1038/s41388-019-0935-y. [Epub ahead of print]


Never Travel Alone: The Crosstalk of Circulating Tumor Cells and the Blood Microenvironment.

Heeke S, Mograbi B, Alix-Panabières C, Hofman P.

Cells. 2019 Jul 13;8(7). pii: E714. doi: 10.3390/cells8070714. Review.


A pilot randomized controlled trial of a gratitude intervention for adolescents with Type 1 diabetes.

Schache KR, Hofman PL, Serlachius AS.

Diabet Med. 2019 Jul 17. doi: 10.1111/dme.14078. [Epub ahead of print]


Microstructural white matter changes preceding white matter hyperintensities in migraine.

Arkink EB, Palm-Meinders IH, Koppen H, Milles J, van Lew B, Launer LJ, Hofman PAM, Terwindt GM, van Buchem MA, Ferrari MD, Kruit MC.

Neurology. 2019 Aug 13;93(7):e688-e694. doi: 10.1212/WNL.0000000000007940. Epub 2019 Jul 11.


Post-mortem computed tomography in forensic investigations of lethal gunshot incidents: is there an added value?

van Kan RAT, Haest IIH, Lobbes MBI, Kroll J, Ernst SR, Kubat B, Hofman PAM.

Int J Legal Med. 2019 Jul 1. doi: 10.1007/s00414-019-02108-y. [Epub ahead of print]


[Pseudo-tumor lesions induced by infectious agents. Case no. 8].

Hofman P, Benzaquen J, Lassalle S, Diascorn Y, Cohen C.

Ann Pathol. 2019 Aug;39(4):277-279. doi: 10.1016/j.annpat.2019.04.005. Epub 2019 Jun 26. French. No abstract available.


[Pseudo-tumor lesions induced by infectious agents. Case no. 7].

Hofman P, Benzaquen J, Diascorn Y, Cohen C.

Ann Pathol. 2019 Aug;39(4):274-276. doi: 10.1016/j.annpat.2019.04.006. Epub 2019 Jun 26. French. No abstract available.


Toward precision medicine based on the molecular landscape of carcinoma in situ of the bronchus: is it realistic for patients with pre-invasive lung disease?

Hofman P.

J Thorac Dis. 2019 May;11(Suppl 9):S1286-S1288. doi: 10.21037/jtd.2019.04.87. No abstract available.


Partial remission in type 1 diabetes and associated factors: Analysis based on the insulin dose-adjusted hemoglobin A1c in children and adolescents from a regional diabetes center, Auckland, New Zealand.

Chiavaroli V, Derraik JGB, Jalaludin MY, Albert BB, Ramkumar S, Cutfield WS, Hofman PL, Jefferies CA.

Pediatr Diabetes. 2019 Jun 25. doi: 10.1111/pedi.12881. [Epub ahead of print]


Correction: Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy.

Fumet JD, Richard C, Ledys F, Klopfenstein Q, Joubert P, Routy B, Truntzer C, Gagné A, Hamel MA, Guimaraes CF, Coudert B, Arnould L, Favier L, Lagrange A, Ladoire S, Saintigny P, Ortiz-Cuaran S, Perol M, Foucher P, Hofman P, Ilie M, Chevrier S, Boidot R, Derangere V, Ghiringhelli F.

Br J Cancer. 2019 Jul;121(3):283. doi: 10.1038/s41416-019-0512-8.


Liquid biopsy in the era of immune-oncology. Is it ready for prime-time use for cancer patients?

Hofman P, Heeke S, Alix-Panabières C, Pantel K.

Ann Oncol. 2019 Jun 22. pii: mdz196. doi: 10.1093/annonc/mdz196. [Epub ahead of print]


Compound heterozygosity for a frameshift mutation and an upstream deletion that reduces expression of SERPINH1 in siblings with a moderate form of osteogenesis imperfecta.

Schwarze U, Cundy T, Liu YJ, Hofman PL, Byers PH.

Am J Med Genet A. 2019 Aug;179(8):1466-1475. doi: 10.1002/ajmg.a.61170. Epub 2019 Jun 9.


The impact of demographic factors on newborn TSH levels and congenital hypothyroidism screening.

Heather NL, Derraik JGB, Webster D, Hofman PL.

Clin Endocrinol (Oxf). 2019 Jun 4. doi: 10.1111/cen.14044. [Epub ahead of print]


Screening for brain metastases in patients with stage III non-small-cell lung cancer, magnetic resonance imaging or computed tomography? A prospective study.

Schoenmaekers J, Hofman P, Bootsma G, Westenend M, de Booij M, Schreurs W, Houben R, De Ruysscher D, Dingemans AM, Hendriks LEL.

Eur J Cancer. 2019 Jul;115:88-96. doi: 10.1016/j.ejca.2019.04.017. Epub 2019 May 23.


The importance of rurality data in understanding access to healthcare services for childhood obesity.

Wild CE, Grant CC, Cave TL, Wynter LE, Derraik JG, Willing EJ, Hofman PL, Anderson YC.

N Z Med J. 2019 May 3;132(1494):60-63. No abstract available.


Is the onset of adverse effects of immunotherapy always bad news for the patients…?-certainly not!

Hofman P.

Ann Transl Med. 2019 Mar;7(Suppl 1):S5. doi: 10.21037/atm.2019.01.14. No abstract available.


Companion diagnostic tests for treatment of lung cancer patients: what are the current and future challenges?

Hofman P, Barlesi F.

Expert Rev Mol Diagn. 2019 May;19(5):429-438. doi: 10.1080/14737159.2019.1611426. Epub 2019 May 6.


[Pseudotumor lesions induced by infectious agents. Introduction].

Hofman P, Tauziède-Espariat A.

Ann Pathol. 2019 Aug;39(4):246-247. doi: 10.1016/j.annpat.2019.03.004. Epub 2019 Apr 16. French. No abstract available.


Multicenter Evaluation of a Novel ROS1 Immunohistochemistry Assay (SP384) for Detection of ROS1 Rearrangements in a Large Cohort of Lung Adenocarcinoma Patients.

Hofman V, Rouquette I, Long-Mira E, Piton N, Chamorey E, Heeke S, Vignaud JM, Yguel C, Mazières J, Lepage AL, Bibeau F, Begueret H, Lassalle S, Lalvée S, Zahaf K, Benzaquen J, Poudenx M, Marquette CH, Sabourin JC, Ilié M, Hofman P.

J Thorac Oncol. 2019 Jul;14(7):1204-1212. doi: 10.1016/j.jtho.2019.03.024. Epub 2019 Apr 15.


PD1/PD-L1 inhibitor treatment for late stage non-small cell lung carcinoma, sometimes…does more harm than good!

Hofman P.

J Thorac Dis. 2019 Mar;11(Suppl 3):S396-S398. doi: 10.21037/jtd.2018.11.140. No abstract available.


Symptomatic Carotid Plaques Demonstrate Less Leaky Plaque Microvasculature Compared With the Contralateral Side: A Dynamic Contrast-Enhanced Magnetic Resonance Imaging Study.

Crombag GAJC, van Hoof RHM, Holtackers RJ, Schreuder FHBM, Truijman MTB, Schreuder TAHCML, van Orshoven NP, Mess WH, Hofman PAM, van Oostenbrugge RJ, Wildberger JE, Kooi ME.

J Am Heart Assoc. 2019 Apr 16;8(8):e011832. doi: 10.1161/JAHA.118.011832.


The Long Noncoding RNA DNM3OS Is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF-β and Pulmonary Fibrosis.

Savary G, Dewaeles E, Diazzi S, Buscot M, Nottet N, Fassy J, Courcot E, Henaoui IS, Lemaire J, Martis N, Van der Hauwaert C, Pons N, Magnone V, Leroy S, Hofman V, Plantier L, Lebrigand K, Paquet A, Lino Cardenas CL, Vassaux G, Hofman P, Günther A, Crestani B, Wallaert B, Rezzonico R, Brousseau T, Glowacki F, Bellusci S, Perrais M, Broly F, Barbry P, Marquette CH, Cauffiez C, Mari B, Pottier N.

Am J Respir Crit Care Med. 2019 Jul 15;200(2):184-198. doi: 10.1164/rccm.201807-1237OC.


Caregiver's readiness for change as a predictor of outcome and attendance in an intervention programme for children and adolescents with obesity: a secondary data analysis.

Anderson YC, Dolan GMS, Wynter LE, Treves KF, Wouldes TA, Grant CC, Cave TL, Smiley AJ, Derraik JGB, Cutfield WS, Hofman PL.

BMJ Open. 2019 Mar 27;9(3):e023195. doi: 10.1136/bmjopen-2018-023195.


Are There New Biomarkers in Tissue and Liquid Biopsies for the Early Detection of Non-Small Cell Lung Cancer?

Calabrese F, Lunardi F, Pezzuto F, Fortarezza F, Vuljan SE, Marquette C, Hofman P.

J Clin Med. 2019 Mar 26;8(3). pii: E414. doi: 10.3390/jcm8030414. Review.


DNAshell Protects DNA Stored at Room Temperature for Downstream Next-Generation Sequencing Studies.

Washetine K, Heeke S, Ribeyre C, Bourreau C, Normand C, Blons H, Laurent-Puig P, Mulot C, Clermont D, David M, Clément B, Dagher G, Hofman P.

Biopreserv Biobank. 2019 Aug;17(4):352-354. doi: 10.1089/bio.2018.0129. Epub 2019 Mar 26. No abstract available.


Is CT bulletproof? On the use of CT for characterization of bullets in forensic radiology.

Paulis LE, Kroll J, Heijnens L, Huijnen M, Gerretsen R, Backes WH, Hofman PAM.

Int J Legal Med. 2019 Mar 26. doi: 10.1007/s00414-019-02033-0. [Epub ahead of print]


Idiopathic short stature and growth hormone sensitivity in prepubertal children.

Derraik JGB, Miles HL, Chiavaroli V, Hofman PL, Cutfield WS.

Clin Endocrinol (Oxf). 2019 Jul;91(1):110-117. doi: 10.1111/cen.13976. Epub 2019 Apr 10.


Dissecting heterogeneity in malignant pleural mesothelioma through histo-molecular gradients for clinical applications.

Blum Y, Meiller C, Quetel L, Elarouci N, Ayadi M, Tashtanbaeva D, Armenoult L, Montagne F, Tranchant R, Renier A, de Koning L, Copin MC, Hofman P, Hofman V, Porte H, Le Pimpec-Barthes F, Zucman-Rossi J, Jaurand MC, de Reyniès A, Jean D.

Nat Commun. 2019 Mar 22;10(1):1333. doi: 10.1038/s41467-019-09307-6.


Recent advances in the molecular landscape of lung neuroendocrine tumors.

Pelosi G, Bianchi F, Hofman P, Pattini L, Ströbel P, Calabrese F, Naheed S, Holden C, Cave J, Bohnenberger H, Dinter H, Harari S, Albini A, Sonzogni A, Papotti M, Volante M, Ottensmeier CH.

Expert Rev Mol Diagn. 2019 Apr;19(4):281-297. doi: 10.1080/14737159.2019.1595593. Epub 2019 Mar 27.


[Tumor banks and complex data management: Current and future challenges].

Hofman P, Dagher G, Laurent-Puig P, Marquette CH, Barlesi F, Bibeau F, Clément B.

Ann Pathol. 2019 Apr;39(2):137-143. doi: 10.1016/j.annpat.2019.01.017. Epub 2019 Feb 25. French.


Multiplexed Immunohistochemistry for Molecular and Immune Profiling in Lung Cancer-Just About Ready for Prime-Time?

Hofman P, Badoual C, Henderson F, Berland L, Hamila M, Long-Mira E, Lassalle S, Roussel H, Hofman V, Tartour E, Ilié M.

Cancers (Basel). 2019 Feb 27;11(3). pii: E283. doi: 10.3390/cancers11030283. Review.


Circulating Tumor Cell Detection in Lung Cancer: But to What End?

Hofman V, Heeke S, Marquette CH, Ilié M, Hofman P.

Cancers (Basel). 2019 Feb 23;11(2). pii: E262. doi: 10.3390/cancers11020262. Review.


The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again.

Hofman P, Ayache N, Barbry P, Barlaud M, Bel A, Blancou P, Checler F, Chevillard S, Cristofari G, Demory M, Esnault V, Falandry C, Gilson E, Guérin O, Glaichenhaus N, Guigay J, Ilié M, Mari B, Marquette CH, Paquis-Flucklinger V, Prate F, Saintigny P, Seitz-Polsky B, Skhiri T, Van Obberghen-Schilling E, Van Obberghen E, Yvan-Charvet L.

Cancers (Basel). 2019 Feb 21;11(2). pii: E250. doi: 10.3390/cancers11020250.


Do changes in weight status affect cognitive function in children and adolescents with obesity? A secondary analysis of a clinical trial.

Anderson YC, Kirkpatrick K, Dolan GMS, Wouldes TA, Grant CC, Cave TL, Wild CEK, Derraik JGB, Cutfield WS, Hofman PL.

BMJ Open. 2019 Feb 19;9(2):e021586. doi: 10.1136/bmjopen-2018-021586.


Circulating free tumor DNA in non-small cell lung cancer (NSCLC): clinical application and future perspectives.

Herbreteau G, Vallée A, Charpentier S, Normanno N, Hofman P, Denis MG.

J Thorac Dis. 2019 Jan;11(Suppl 1):S113-S126. doi: 10.21037/jtd.2018.12.18. Review.


Current views on tumor mutational burden in patients with non-small cell lung cancer treated by immune checkpoint inhibitors.

Berland L, Heeke S, Humbert O, Macocco A, Long-Mira E, Lassalle S, Lespinet-Fabre V, Lalvée S, Bordone O, Cohen C, Leroy S, Hofman V, Hofman P, Ilié M.

J Thorac Dis. 2019 Jan;11(Suppl 1):S71-S80. doi: 10.21037/jtd.2018.11.102. Review.


Resistances to EGFR tyrosine kinase inhibitors in lung cancer-how to routinely track them in a molecular pathology laboratory?

Hofman V, Hofman P.

J Thorac Dis. 2019 Jan;11(Suppl 1):S65-S70. doi: 10.21037/jtd.2018.11.76. Review.


Advances in theranostic biomarkers for lung cancer from clinical to molecular pathology.

Hofman P.

J Thorac Dis. 2019 Jan;11(Suppl 1):S1-S2. doi: 10.21037/jtd.2018.10.28. No abstract available.


[The age of artificial intelligence in lung cancer pathology: Between hope, gloom and perspectives].

Heeke S, Delingette H, Fanjat Y, Long-Mira E, Lassalle S, Hofman V, Benzaquen J, Marquette CH, Hofman P, Ilié M.

Ann Pathol. 2019 Apr;39(2):130-136. doi: 10.1016/j.annpat.2019.01.003. Epub 2019 Feb 13. French.


Lung Cancer Screening, Towards a Multidimensional Approach: Why and How?

Benzaquen J, Boutros J, Marquette C, Delingette H, Hofman P.

Cancers (Basel). 2019 Feb 12;11(2). pii: E212. doi: 10.3390/cancers11020212. Review.


The Desire to Better Understand Older Adults with Solid Tumors to Improve Management: Assessment and Guided Interventions-The French PACA EST Cohort Experience.

Boulahssass R, Gonfrier S, Champigny N, Lassalle S, François E, Hofman P, Guerin O.

Cancers (Basel). 2019 Feb 7;11(2). pii: E192. doi: 10.3390/cancers11020192.


[Thoracic oncology and tumor mutational burden: Towards new challenges for the pathologist?]

Hofman P.

Ann Pathol. 2019 Jun;39(3):212-220. doi: 10.1016/j.annpat.2018.12.008. Epub 2019 Jan 30. French.


Monitoring BRAF and NRAS mutations with cell-free circulating tumor DNA from metastatic melanoma patients.

Long-Mira E, Ilie M, Chamorey E, Leduff-Blanc F, Montaudié H, Tanga V, Allégra M, Lespinet-Fabre V, Bordone O, Bonnetaud C, Schiappa R, Butori C, Bence C, Lacour JP, Hofman V, Hofman P.

Oncotarget. 2018 Nov 16;9(90):36238-36249. doi: 10.18632/oncotarget.26343. eCollection 2018 Nov 16.


Severe Familial Hypertriglyceridemia: Successful Treatment With Insulin and a Modified Meal Plan.

Ayyavoo A, Raghupathy P, Agarwal M, Hofman P.

J Endocr Soc. 2018 Nov 1;2(12):1357-1362. doi: 10.1210/js.2018-00299. eCollection 2018 Dec 1.


Tumor mutational burden assessment as a predictive biomarker for immunotherapy in lung cancer patients: getting ready for prime-time or not?

Heeke S, Hofman P.

Transl Lung Cancer Res. 2018 Dec;7(6):631-638. doi: 10.21037/tlcr.2018.08.04. Review.


Spotlight on tumor mutational burden in patients with non-small cell lung carcinoma.

Ilie M, Hofman P.

Transl Lung Cancer Res. 2018 Dec;7(6):614-615. doi: 10.21037/tlcr.2018.08.06. No abstract available.


Gratitude - more than just a platitude? The science behind gratitude and health.

Schache K, Consedine N, Hofman P, Serlachius A.

Br J Health Psychol. 2019 Feb;24(1):1-9. doi: 10.1111/bjhp.12348. Epub 2018 Nov 28. No abstract available.


[Next generation biobanking: the challenge of data].

Dagher G, Lavitrano ML, Hofman P.

Med Sci (Paris). 2018 Oct;34(10):849-851. doi: 10.1051/medsci/2018203. Epub 2018 Nov 19. Review. French.


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