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Items: 1 to 50 of 102

1.

ARAP1 Bridges Actin Dynamics and AP-3-Dependent Membrane Traffic in Bone-Digesting Osteoclasts.

Segeletz S, Danglot L, Galli T, Hoflack B.

iScience. 2018 Aug 31;6:199-211. doi: 10.1016/j.isci.2018.07.019. Epub 2018 Jul 26.

2.

Spatiotemporal Control of Lipid Conversion, Actin-Based Mechanical Forces, and Curvature Sensors during Clathrin/AP-1-Coated Vesicle Biogenesis.

Anitei M, Stange C, Czupalla C, Niehage C, Schuhmann K, Sala P, Czogalla A, Pursche T, Coskun Ü, Shevchenko A, Hoflack B.

Cell Rep. 2017 Aug 29;20(9):2087-2099. doi: 10.1016/j.celrep.2017.08.013.

3.

L-leucyl-L-leucine methyl ester does not release cysteine cathepsins to the cytosol but inactivates them in transiently permeabilized lysosomes.

Repnik U, Borg Distefano M, Speth MT, Ng MYW, Progida C, Hoflack B, Gruenberg J, Griffiths G.

J Cell Sci. 2017 Sep 15;130(18):3124-3140. doi: 10.1242/jcs.204529. Epub 2017 Jul 28.

4.

Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport.

Hinckelmann MV, Virlogeux A, Niehage C, Poujol C, Choquet D, Hoflack B, Zala D, Saudou F.

Nat Commun. 2016 Oct 24;7:13233. doi: 10.1038/ncomms13233.

5.

BAR Proteins PSTPIP1/2 Regulate Podosome Dynamics and the Resorption Activity of Osteoclasts.

Sztacho M, Segeletz S, Sanchez-Fernandez MA, Czupalla C, Niehage C, Hoflack B.

PLoS One. 2016 Oct 19;11(10):e0164829. doi: 10.1371/journal.pone.0164829. eCollection 2016.

6.

Cell Surface Proteome of Dental Pulp Stem Cells Identified by Label-Free Mass Spectrometry.

Niehage C, Karbanová J, Steenblock C, Corbeil D, Hoflack B.

PLoS One. 2016 Aug 4;11(8):e0159824. doi: 10.1371/journal.pone.0159824. eCollection 2016.

7.

Proteomic approaches to study osteoclast biology.

Segeletz S, Hoflack B.

Proteomics. 2016 Oct;16(19):2545-2556. doi: 10.1002/pmic.201500519. Epub 2016 Aug 4. Review.

PMID:
27350065
8.

Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex.

Imle A, Abraham L, Tsopoulidis N, Hoflack B, Saksela K, Fackler OT.

MBio. 2015 Sep 8;6(5):e01309-15. doi: 10.1128/mBio.01309-15.

9.

The Amyloid Precursor Protein Controls PIKfyve Function.

Balklava Z, Niehage C, Currinn H, Mellor L, Guscott B, Poulin G, Hoflack B, Wassmer T.

PLoS One. 2015 Jun 30;10(6):e0130485. doi: 10.1371/journal.pone.0130485. eCollection 2015.

10.

Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis.

Traikov S, Stange C, Wassmer T, Paul-Gilloteaux P, Salamero J, Raposo G, Hoflack B.

PLoS One. 2014 Nov 7;9(11):e109372. doi: 10.1371/journal.pone.0109372. eCollection 2014.

11.

A high-throughput siRNA screen identifies genes that regulate mannose 6-phosphate receptor trafficking.

Anitei M, Chenna R, Czupalla C, Esner M, Christ S, Lenhard S, Korn K, Meyenhofer F, Bickle M, Zerial M, Hoflack B.

J Cell Sci. 2014 Dec 1;127(Pt 23):5079-92. doi: 10.1242/jcs.159608. Epub 2014 Oct 2.

12.

Proteomic analysis reveals a novel function of the kinase Sat4p in Saccharomyces cerevisiae mitochondria.

Gey U, Czupalla C, Hoflack B, Krause U, Rödel G.

PLoS One. 2014 Aug 12;9(8):e103956. doi: 10.1371/journal.pone.0103956. eCollection 2014.

13.

The Cdc42 guanine nucleotide exchange factor FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts.

Steenblock C, Heckel T, Czupalla C, Espírito Santo AI, Niehage C, Sztacho M, Hoflack B.

J Biol Chem. 2014 Jun 27;289(26):18347-59. doi: 10.1074/jbc.M113.504894. Epub 2014 May 12.

14.

Proteomic and functional consequences of hexokinase deficiency in glucose-repressible Kluyveromyces lactis.

Mates N, Kettner K, Heidenreich F, Pursche T, Migotti R, Kahlert G, Kuhlisch E, Breunig KD, Schellenberger W, Dittmar G, Hoflack B, Kriegel TM.

Mol Cell Proteomics. 2014 Mar;13(3):860-75. doi: 10.1074/mcp.M113.032714. Epub 2014 Jan 16.

15.

Liposome-based assays to study membrane-associated protein networks.

Niehage C, Stange C, Anitei M, Hoflack B.

Methods Enzymol. 2014;534:223-43. doi: 10.1016/B978-0-12-397926-1.00013-5.

PMID:
24359957
16.

Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments.

Prewitz MC, Seib FP, von Bonin M, Friedrichs J, Stißel A, Niehage C, Müller K, Anastassiadis K, Waskow C, Hoflack B, Bornhäuser M, Werner C.

Nat Methods. 2013 Aug;10(8):788-94. doi: 10.1038/nmeth.2523. Epub 2013 Jun 23.

PMID:
23793238
17.

Transgenic mice for a tamoxifen-induced, conditional expression of the Cre recombinase in osteoclasts.

Sanchez-Fernandez MA, Sbacchi S, Correa-Tapia M, Naumann R, Klemm J, Chambon P, Al-Robaiy S, Blessing M, Hoflack B.

PLoS One. 2012;7(5):e37592. doi: 10.1371/journal.pone.0037592. Epub 2012 May 18.

18.

Saccharomyces cerevisiae porin pore forms complexes with mitochondrial outer membrane proteins Om14p and Om45p.

Lauffer S, Mäbert K, Czupalla C, Pursche T, Hoflack B, Rödel G, Krause-Buchholz U.

J Biol Chem. 2012 May 18;287(21):17447-58. doi: 10.1074/jbc.M111.328328. Epub 2012 Mar 29.

19.

Bridging membrane and cytoskeleton dynamics in the secretory and endocytic pathways.

Anitei M, Hoflack B.

Nat Cell Biol. 2011 Dec 22;14(1):11-9. doi: 10.1038/ncb2409. Review.

PMID:
22193159
20.

Retromer controls epithelial cell polarity by trafficking the apical determinant Crumbs.

Pocha SM, Wassmer T, Niehage C, Hoflack B, Knust E.

Curr Biol. 2011 Jul 12;21(13):1111-7. doi: 10.1016/j.cub.2011.05.007. Epub 2011 Jun 23.

21.

The cell surface proteome of human mesenchymal stromal cells.

Niehage C, Steenblock C, Pursche T, Bornhäuser M, Corbeil D, Hoflack B.

PLoS One. 2011;6(5):e20399. doi: 10.1371/journal.pone.0020399. Epub 2011 May 26.

22.

Exit from the trans-Golgi network: from molecules to mechanisms.

Anitei M, Hoflack B.

Curr Opin Cell Biol. 2011 Aug;23(4):443-51. doi: 10.1016/j.ceb.2011.03.013. Epub 2011 May 6. Review.

PMID:
21550789
23.

Identification of increased amounts of eppin protein complex components in sperm cells of diabetic and obese individuals by difference gel electrophoresis.

Paasch U, Heidenreich F, Pursche T, Kuhlisch E, Kettner K, Grunewald S, Kratzsch J, Dittmar G, Glander HJ, Hoflack B, Kriegel TM.

Mol Cell Proteomics. 2011 Aug;10(8):M110.007187. doi: 10.1074/mcp.M110.007187. Epub 2011 Apr 27.

24.

Endospanins regulate a postinternalization step of the leptin receptor endocytic pathway.

Séron K, Couturier C, Belouzard S, Bacart J, Monté D, Corset L, Bocquet O, Dam J, Vauthier V, Lecœur C, Bailleul B, Hoflack B, Froguel P, Jockers R, Rouillé Y.

J Biol Chem. 2011 May 20;286(20):17968-81. doi: 10.1074/jbc.M111.224857. Epub 2011 Mar 22.

25.

Bidirectional transport between the trans-Golgi network and the endosomal system.

Anitei M, Wassmer T, Stange C, Hoflack B.

Mol Membr Biol. 2010 Nov;27(8):443-56. doi: 10.3109/09687688.2010.522601. Epub 2010 Nov 5. Review.

PMID:
21054155
26.

Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN.

Anitei M, Stange C, Parshina I, Baust T, Schenck A, Raposo G, Kirchhausen T, Hoflack B.

Nat Cell Biol. 2010 Apr;12(4):330-40. doi: 10.1038/ncb2034. Epub 2010 Mar 14. Erratum in: Nat Cell Biol. 2010 May;12(5):520.

27.

Identification of diabetes- and obesity-associated proteomic changes in human spermatozoa by difference gel electrophoresis.

Kriegel TM, Heidenreich F, Kettner K, Pursche T, Hoflack B, Grunewald S, Poenicke K, Glander HJ, Paasch U.

Reprod Biomed Online. 2009 Nov;19(5):660-70.

PMID:
20021714
28.

Src-dependent repression of ARF6 is required to maintain podosome-rich sealing zones in bone-digesting osteoclasts.

Heckel T, Czupalla C, Expirto Santo AI, Anitei M, Arantzazu Sanchez-Fernandez M, Mosch K, Krause E, Hoflack B.

Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1451-6. doi: 10.1073/pnas.0804464106. Epub 2009 Jan 21.

29.

Osteoclasts control osteoblast chemotaxis via PDGF-BB/PDGF receptor beta signaling.

Sanchez-Fernandez MA, Gallois A, Riedl T, Jurdic P, Hoflack B.

PLoS One. 2008;3(10):e3537. doi: 10.1371/journal.pone.0003537. Epub 2008 Oct 27.

30.

Rapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells.

Süss C, Czupalla C, Winter C, Pursche T, Knoch KP, Schroeder M, Hoflack B, Solimena M.

Mol Cell Proteomics. 2009 Mar;8(3):393-408. doi: 10.1074/mcp.M800157-MCP200. Epub 2008 Oct 14.

31.

Protein networks supporting AP-3 function in targeting lysosomal membrane proteins.

Baust T, Anitei M, Czupalla C, Parshyna I, Bourel L, Thiele C, Krause E, Hoflack B.

Mol Biol Cell. 2008 May;19(5):1942-51. doi: 10.1091/mbc.E08-02-0110. Epub 2008 Feb 20.

32.

Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases.

Gey U, Czupalla C, Hoflack B, Rödel G, Krause-Buchholz U.

J Biol Chem. 2008 Apr 11;283(15):9759-67. doi: 10.1074/jbc.M708779200. Epub 2008 Jan 7.

33.

Proteomic analysis of adaptor protein 1A coats selectively assembled on liposomes.

Baust T, Czupalla C, Krause E, Bourel-Bonnet L, Hoflack B.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3159-64. Epub 2006 Feb 21.

34.

Proteomic analysis of lysosomal acid hydrolases secreted by osteoclasts: implications for lytic enzyme transport and bone metabolism.

Czupalla C, Mansukoski H, Riedl T, Thiel D, Krause E, Hoflack B.

Mol Cell Proteomics. 2006 Jan;5(1):134-43. Epub 2005 Oct 8.

35.

Identification of actin as quercetin-binding protein: an approach to identify target molecules for specific ligands.

Böhl M, Czupalla C, Tokalov SV, Hoflack B, Gutzeit HO.

Anal Biochem. 2005 Nov 15;346(2):295-9. Epub 2005 Sep 19.

PMID:
16213457
36.

Comparative study of protein and mRNA expression during osteoclastogenesis.

Czupalla C, Mansukoski H, Pursche T, Krause E, Hoflack B.

Proteomics. 2005 Oct;5(15):3868-75.

PMID:
16145714
37.

Anchorage of synthetic peptides onto liposomes via hydrazone and alpha-oxo hydrazone bonds. preliminary functional investigations.

Bourel-Bonnet L, Pécheur EI, Grandjean C, Blanpain A, Baust T, Melnyk O, Hoflack B, Gras-Masse H.

Bioconjug Chem. 2005 Mar-Apr;16(2):450-7.

PMID:
15769100
38.

Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cells.

Waguri S, Dewitte F, Le Borgne R, Rouillé Y, Uchiyama Y, Dubremetz JF, Hoflack B.

Mol Biol Cell. 2003 Jan;14(1):142-55.

39.

Yeast Vps55p, a functional homolog of human obesity receptor gene-related protein, is involved in late endosome to vacuole trafficking.

Belgareh-Touzé N, Avaro S, Rouillé Y, Hoflack B, Haguenauer-Tsapis R.

Mol Biol Cell. 2002 May;13(5):1694-708.

40.

The AP-3-dependent targeting of the melanosomal glycoprotein QNR-71 requires a di-leucine-based sorting signal.

Le Borgne R, Planque N, Martin P, Dewitte F, Saule S, Hoflack B.

J Cell Sci. 2001 Aug;114(Pt 15):2831-41.

41.

Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain.

Nielsen E, Christoforidis S, Uttenweiler-Joseph S, Miaczynska M, Dewitte F, Wilm M, Hoflack B, Zerial M.

J Cell Biol. 2000 Oct 30;151(3):601-12.

42.

Targeting of lysosomal proteins.

Rouillé Y, Rohn W, Hoflack B.

Semin Cell Dev Biol. 2000 Jun;11(3):165-71. Review.

PMID:
10906273
43.

Bi-directional trafficking between the trans-Golgi network and the endosomal/lysosomal system.

Rohn WM, Rouillé Y, Waguri S, Hoflack B.

J Cell Sci. 2000 Jun;113 ( Pt 12):2093-101.

44.

Mannose 6-Phosphate/Insulin-like growth factor II receptor mediates internalization and degradation of leukemia inhibitory factor but not signal transduction.

Blanchard F, Duplomb L, Raher S, Vusio P, Hoflack B, Jacques Y, Godard A.

J Biol Chem. 1999 Aug 27;274(35):24685-93.

45.

Sorting of furin at the trans-Golgi network. Interaction of the cytoplasmic tail sorting signals with AP-1 Golgi-specific assembly proteins.

Teuchert M, Schäfer W, Berghöfer S, Hoflack B, Klenk HD, Garten W.

J Biol Chem. 1999 Mar 19;274(12):8199-207.

47.

The mammalian AP-3 adaptor-like complex mediates the intracellular transport of lysosomal membrane glycoproteins.

Le Borgne R, Alconada A, Bauer U, Hoflack B.

J Biol Chem. 1998 Nov 6;273(45):29451-61.

48.

Mechanisms of protein sorting and coat assembly: insights from the clathrin-coated vesicle pathway.

Le Borgne R, Hoflack B.

Curr Opin Cell Biol. 1998 Aug;10(4):499-503. Review.

PMID:
9719871
49.

Protein transport from the secretory to the endocytic pathway in mammalian cells.

Le Borgne R, Hoflack B.

Biochim Biophys Acta. 1998 Aug 14;1404(1-2):195-209. Review.

50.

The mannose 6-phosphate/insulin-like growth factor II receptor is a nanomolar affinity receptor for glycosylated human leukemia inhibitory factor.

Blanchard F, Raher S, Duplomb L, Vusio P, Pitard V, Taupin JL, Moreau JF, Hoflack B, Minvielle S, Jacques Y, Godard A.

J Biol Chem. 1998 Aug 14;273(33):20886-93.

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