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1.

Erratum to 'Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni' [IJP Drugs Drug Resist. 8 (2018) 559-570].

Padalino G, Ferla S, Brancale A, Chalmers IW, Hoffmann KF.

Int J Parasitol Drugs Drug Resist. 2019 Jul 2;10:91. doi: 10.1016/j.ijpddr.2019.07.001. [Epub ahead of print] No abstract available.

2.

The Anti-mycobacterial Activity of a Diterpenoid-Like Molecule Operates Through Nitrogen and Amino Acid Starvation.

Crusco A, Baptista R, Bhowmick S, Beckmann M, Mur LAJ, Westwell AD, Hoffmann KF.

Front Microbiol. 2019 Jun 25;10:1444. doi: 10.3389/fmicb.2019.01444. eCollection 2019.

3.

Schistosoma mansoni venom allergen-like proteins: phylogenetic relationships, stage-specific transcription and tissue localization as predictors of immunological cross-reactivity.

Farias LP, Chalmers IW, Perally S, Rofatto HK, Jackson CJ, Brown M, Khouri MI, Barbosa MMF, Hensbergen PJ, Hokke CH, Leite LCC, Hoffmann KF.

Int J Parasitol. 2019 Jul;49(8):593-599. doi: 10.1016/j.ijpara.2019.03.003. Epub 2019 May 25.

4.

Antischistosomal Properties of Sclareol and Its Heck-Coupled Derivatives: Design, Synthesis, Biological Evaluation, and Untargeted Metabolomics.

Crusco A, Whiteland H, Baptista R, Forde-Thomas JE, Beckmann M, Mur LAJ, Nash RJ, Westwell AD, Hoffmann KF.

ACS Infect Dis. 2019 Jul 12;5(7):1188-1199. doi: 10.1021/acsinfecdis.9b00034. Epub 2019 May 28.

PMID:
31083889
5.

Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni.

Ittiprasert W, Mann VH, Karinshak SE, Coghlan A, Rinaldi G, Sankaranarayanan G, Chaidee A, Tanno T, Kumkhaek C, Prangtaworn P, Mentink-Kane MM, Cochran CJ, Driguez P, Holroyd N, Tracey A, Rodpai R, Everts B, Hokke CH, Hoffmann KF, Berriman M, Brindley PJ.

Elife. 2019 Jan 15;8. pii: e41337. doi: 10.7554/eLife.41337.

6.

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borràs FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MÁ, Brigstock DR, Brisson A, Broekman ML, Bromberg JF, Bryl-Górecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzás EI, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FA, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana EF, De Wever O, Del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, Ekström K, El Andaloussi S, Elie-Caille C, Erdbrügger U, Falcón-Pérez JM, Fatima F, Fish JE, Flores-Bellver M, Försönits A, Frelet-Barrand A, Fricke F, Fuhrmann G, Gabrielsson S, Gámez-Valero A, Gardiner C, Gärtner K, Gaudin R, Gho YS, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan DC, Görgens A, Gorski SM, Greening DW, Gross JC, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P, Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AG, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L, Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ 2nd, Kornek M, Kosanović MM, Kovács ÁF, Krämer-Albers EM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lässer C, Laurent LC, Lavieu G, Lázaro-Ibáñez E, Le Lay S, Lee MS, Lee YXF, Lemos DS, Lenassi M, Leszczynska A, Li IT, Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Linē A, Linnemannstöns K, Llorente A, Lombard CA, Lorenowicz MJ, Lörincz ÁM, Lötvall J, Lovett J, Lowry MC, Loyer X, Lu Q, Lukomska B, Lunavat TR, Maas SL, Malhi H, Marcilla A, Mariani J, Mariscal J, Martens-Uzunova ES, Martin-Jaular L, Martinez MC, Martins VR, Mathieu M, Mathivanan S, Maugeri M, McGinnis LK, McVey MJ, Meckes DG Jr, Meehan KL, Mertens I, Minciacchi VR, Möller A, Møller Jørgensen M, Morales-Kastresana A, Morhayim J, Mullier F, Muraca M, Musante L, Mussack V, Muth DC, Myburgh KH, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri C, Neri T, Nieuwland R, Nimrichter L, Nolan JP, Nolte-'t Hoen EN, Noren Hooten N, O'Driscoll L, O'Grady T, O'Loghlen A, Ochiya T, Olivier M, Ortiz A, Ortiz LA, Osteikoetxea X, Østergaard O, Ostrowski M, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Phinney DG, Pieters BC, Pink RC, Pisetsky DS, Pogge von Strandmann E, Polakovicova I, Poon IK, Powell BH, Prada I, Pulliam L, Quesenberry P, Radeghieri A, Raffai RL, Raimondo S, Rak J, Ramirez MI, Raposo G, Rayyan MS, Regev-Rudzki N, Ricklefs FL, Robbins PD, Roberts DD, Rodrigues SC, Rohde E, Rome S, Rouschop KM, Rughetti A, Russell AE, Saá P, Sahoo S, Salas-Huenuleo E, Sánchez C, Saugstad JA, Saul MJ, Schiffelers RM, Schneider R, Schøyen TH, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke GV, Shetty AK, Shiba K, Siljander PR, Silva AM, Skowronek A, Snyder OL 2nd, Soares RP, Sódar BW, Soekmadji C, Sotillo J, Stahl PD, Stoorvogel W, Stott SL, Strasser EF, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh WS, Tomasini R, Torrecilhas AC, Tosar JP, Toxavidis V, Urbanelli L, Vader P, van Balkom BW, van der Grein SG, Van Deun J, van Herwijnen MJ, Van Keuren-Jensen K, van Niel G, van Royen ME, van Wijnen AJ, Vasconcelos MH, Vechetti IJ Jr, Veit TD, Vella LJ, Velot É, Verweij FJ, Vestad B, Viñas JL, Visnovitz T, Vukman KV, Wahlgren J, Watson DC, Wauben MH, Weaver A, Webber JP, Weber V, Wehman AM, Weiss DJ, Welsh JA, Wendt S, Wheelock AM, Wiener Z, Witte L, Wolfram J, Xagorari A, Xander P, Xu J, Yan X, Yáñez-Mó M, Yin H, Yuana Y, Zappulli V, Zarubova J, Žėkas V, Zhang JY, Zhao Z, Zheng L, Zheutlin AR, Zickler AM, Zimmermann P, Zivkovic AM, Zocco D, Zuba-Surma EK.

J Extracell Vesicles. 2018 Nov 23;7(1):1535750. doi: 10.1080/20013078.2018.1535750. eCollection 2018.

7.

Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni.

Padalino G, Ferla S, Brancale A, Chalmers IW, Hoffmann KF.

Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):559-570. doi: 10.1016/j.ijpddr.2018.10.005. Epub 2018 Nov 13. Erratum in: Int J Parasitol Drugs Drug Resist. 2019 Jul 2;10:91.

8.

An Abies procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola hepatica and Schistosoma mansoni.

Whiteland HL, Chakroborty A, Forde-Thomas JE, Crusco A, Cookson A, Hollinshead J, Fenn CA, Bartholomew B, Holdsworth PA, Fisher M, Nash RJ, Hoffmann KF.

Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):465-474. doi: 10.1016/j.ijpddr.2018.10.009. Epub 2018 Oct 26.

9.

Antibody responses to Schistosoma mansoni schistosomula antigens.

Egesa M, Lubyayi L, Jones FM, van Diepen A, Chalmers IW, Tukahebwa EM, Bagaya BS, Hokke CH, Hoffmann KF, Dunne DW, Elliott AM, Yazdanbakhsh M, Wilson S, Cose S.

Parasite Immunol. 2018 Dec;40(12):e12591. doi: 10.1111/pim.12591. Epub 2018 Oct 14.

10.

Schistosoma mansoni schistosomula antigens induce Th1/Pro-inflammatory cytokine responses.

Egesa M, Lubyayi L, Tukahebwa EM, Bagaya BS, Chalmers IW, Wilson S, Hokke CH, Hoffmann KF, Dunne DW, Yazdanbakhsh M, Labuda LA, Cose S.

Parasite Immunol. 2018 Dec;40(12):e12592. doi: 10.1111/pim.12592. Epub 2018 Oct 21.

11.

Corrigendum to 'the anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities' [Int. J. Parasitol. Drugs and Drug Resist. 8 (2018) 213-222].

Geyer KK, Munshi SE, Vickers M, Squance M, Wilkinson TJ, Berrar D, Chaparro C, Swain MT, Hoffmann KF.

Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):493. doi: 10.1016/j.ijpddr.2018.07.002. Epub 2018 Jul 17. No abstract available.

12.

Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoni.

Geyer KK, Munshi SE, Whiteland HL, Fernandez-Fuentes N, Phillips DW, Hoffmann KF.

PLoS Pathog. 2018 Jun 28;14(6):e1007107. doi: 10.1371/journal.ppat.1007107. eCollection 2018 Jun.

13.

Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni.

Roquis D, Taudt A, Geyer KK, Padalino G, Hoffmann KF, Holroyd N, Berriman M, Aliaga B, Chaparro C, Grunau C, Augusto RC.

PLoS Pathog. 2018 May 21;14(5):e1007066. doi: 10.1371/journal.ppat.1007066. eCollection 2018 May.

14.

Design, synthesis and anthelmintic activity of 7-keto-sempervirol analogues.

Crusco A, Bordoni C, Chakroborty A, Whatley KCL, Whiteland H, Westwell AD, Hoffmann KF.

Eur J Med Chem. 2018 May 25;152:87-100. doi: 10.1016/j.ejmech.2018.04.032. Epub 2018 Apr 17.

15.

The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities.

Geyer KK, Munshi SE, Vickers M, Squance M, Wilkinson TJ, Berrar D, Chaparro C, Swain MT, Hoffmann KF.

Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):213-222. doi: 10.1016/j.ijpddr.2018.03.006. Epub 2018 Apr 1. Erratum in: Int J Parasitol Drugs Drug Resist. 2018 Jul 17;:.

16.

Corrigendum: Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

Adema CM, Hillier LW, Jones CS, Loker ES, Knight M, Minx P, Oliveira G, Raghavan N, Shedlock A, do Amaral LR, Arican-Goktas HD, Assis JG, Baba EH, Baron OL, Bayne CJ, Bickham-Wright U, Biggar KK, Blouin M, Bonning BC, Botka C, Bridger JM, Buckley KM, Buddenborg SK, Lima Caldeira R, Carleton J, Carvalho OS, Castillo MG, Chalmers IW, Christensens M, Clifton S, Cosseau C, Coustau C, Cripps RM, Cuesta-Astroz Y, Cummins SF, Di Stefano L, Dinguirard N, Duval D, Emrich S, Feschotte C, Feyereisen R, FitzGerald P, Fronick C, Fulton L, Galinier R, Gava SG, Geusz M, Geyer KK, Giraldo-Calderón GI, de Souza Gomes M, Gordy MA, Gourbal B, Grunau C, Hanington PC, Hoffmann KF, Hughes D, Humphries J, Jackson DJ, Jannotti-Passos LK, de Jesus Jeremias W, Jobling S, Kamel B, Kapusta A, Kaur S, Koene JM, Kohn AB, Lawson D, Lawton SP, Liang D, Limpanont Y, Liu S, Lockyer AE, Lovato TAL, Ludolf F, Magrini V, McManus DP, Medina M, Misra M, Mitta G, Mkoji GM, Montague MJ, Montelongo C, Moroz LL, Munoz-Torres MC, Niazi U, Noble LR, Oliveira FS, Pais FS, Papenfuss AT, Peace R, Pena JJ, Pila EA, Quelais T, Raney BJ, Rast JP, Rollinson D, Rosse IC, Rotgans B, Routledge EJ, Ryan KM, Scholte LLS, Storey KB, Swain M, Tennessen JA, Tomlinson C, Trujillo DL, Volpi EV, Walker AJ, Wang T, Wannaporn I, Warren WC, Wu XJ, Yoshino TP, Yusuf M, Zhang SM, Zhao M, Wilson RK.

Nat Commun. 2017 Aug 23;8:16153. doi: 10.1038/ncomms16153.

17.

Rethinking Schistosomiasis Vaccine Development: Synthetic Vesicles.

Egesa M, Hoffmann KF, Hokke CH, Yazdanbakhsh M, Cose S.

Trends Parasitol. 2017 Dec;33(12):918-921. doi: 10.1016/j.pt.2017.07.007. Epub 2017 Aug 14.

18.

Neoclerodane Diterpenoids from Reehal Fatima, Teucrium yemense.

Nur-E-Alam M, Yousaf M, Ahmed S, Al-Sheddi ES, Parveen I, Fazakerley DM, Bari A, Ghabbour HA, Threadgill MD, Whatley KCL, Hoffmann KF, Al-Rehaily AJ.

J Nat Prod. 2017 Jun 23;80(6):1900-1908. doi: 10.1021/acs.jnatprod.7b00188. Epub 2017 Jun 5.

PMID:
28581290
19.

The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni.

Geyer KK, Niazi UH, Duval D, Cosseau C, Tomlinson C, Chalmers IW, Swain MT, Cutress DJ, Bickham-Wright U, Munshi SE, Grunau C, Yoshino TP, Hoffmann KF.

PLoS Negl Trop Dis. 2017 May 16;11(5):e0005246. doi: 10.1371/journal.pntd.0005246. eCollection 2017 May.

20.

Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

Adema CM, Hillier LW, Jones CS, Loker ES, Knight M, Minx P, Oliveira G, Raghavan N, Shedlock A, do Amaral LR, Arican-Goktas HD, Assis JG, Baba EH, Baron OL, Bayne CJ, Bickham-Wright U, Biggar KK, Blouin M, Bonning BC, Botka C, Bridger JM, Buckley KM, Buddenborg SK, Lima Caldeira R, Carleton J, Carvalho OS, Castillo MG, Chalmers IW, Christensens M, Clifton S, Cosseau C, Coustau C, Cripps RM, Cuesta-Astroz Y, Cummins SF, di Stephano L, Dinguirard N, Duval D, Emrich S, Feschotte C, Feyereisen R, FitzGerald P, Fronick C, Fulton L, Galinier R, Gava SG, Geusz M, Geyer KK, Giraldo-Calderón GI, de Souza Gomes M, Gordy MA, Gourbal B, Grunau C, Hanington PC, Hoffmann KF, Hughes D, Humphries J, Jackson DJ, Jannotti-Passos LK, de Jesus Jeremias W, Jobling S, Kamel B, Kapusta A, Kaur S, Koene JM, Kohn AB, Lawson D, Lawton SP, Liang D, Limpanont Y, Liu S, Lockyer AE, Lovato TL, Ludolf F, Magrini V, McManus DP, Medina M, Misra M, Mitta G, Mkoji GM, Montague MJ, Montelongo C, Moroz LL, Munoz-Torres MC, Niazi U, Noble LR, Oliveira FS, Pais FS, Papenfuss AT, Peace R, Pena JJ, Pila EA, Quelais T, Raney BJ, Rast JP, Rollinson D, Rosse IC, Rotgans B, Routledge EJ, Ryan KM, Scholte LLS, Storey KB, Swain M, Tennessen JA, Tomlinson C, Trujillo DL, Volpi EV, Walker AJ, Wang T, Wannaporn I, Warren WC, Wu XJ, Yoshino TP, Yusuf M, Zhang SM, Zhao M, Wilson RK.

Nat Commun. 2017 May 16;8:15451. doi: 10.1038/ncomms15451. Erratum in: Nat Commun. 2017 Aug 23;8:16153.

21.

(Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach.

Cosseau C, Wolkenhauer O, Padalino G, Geyer KK, Hoffmann KF, Grunau C.

Trends Parasitol. 2017 Apr;33(4):285-294. doi: 10.1016/j.pt.2016.12.002. Epub 2016 Dec 28. Review.

22.

DISMISS: detection of stranded methylation in MeDIP-Seq data.

Niazi U, Geyer KK, Vickers MJ, Hoffmann KF, Swain MT.

BMC Bioinformatics. 2016 Jul 29;17(1):295. doi: 10.1186/s12859-016-1158-7.

23.

Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoni.

Nowacki FC, Swain MT, Klychnikov OI, Niazi U, Ivens A, Quintana JF, Hensbergen PJ, Hokke CH, Buck AH, Hoffmann KF.

J Extracell Vesicles. 2015 Oct 5;4:28665. doi: 10.3402/jev.v4.28665. eCollection 2015.

24.

Human IgG1 Responses to Surface Localised Schistosoma mansoni Ly6 Family Members Drop following Praziquantel Treatment.

Chalmers IW, Fitzsimmons CM, Brown M, Pierrot C, Jones FM, Wawrzyniak JM, Fernandez-Fuentes N, Tukahebwa EM, Dunne DW, Khalife J, Hoffmann KF.

PLoS Negl Trop Dis. 2015 Jul 6;9(7):e0003920. doi: 10.1371/journal.pntd.0003920. eCollection 2015.

25.

Glycomic Analysis of Life Stages of the Human Parasite Schistosoma mansoni Reveals Developmental Expression Profiles of Functional and Antigenic Glycan Motifs.

Smit CH, van Diepen A, Nguyen DL, Wuhrer M, Hoffmann KF, Deelder AM, Hokke CH.

Mol Cell Proteomics. 2015 Jul;14(7):1750-69. doi: 10.1074/mcp.M115.048280. Epub 2015 Apr 16.

26.

Drug-induced exposure of Schistosoma mansoni antigens SmCD59a and SmKK7.

Reimers N, Homann A, Höschler B, Langhans K, Wilson RA, Pierrot C, Khalife J, Grevelding CG, Chalmers IW, Yazdanbakhsh M, Hoffmann KF, Hokke CH, Haas H, Schramm G.

PLoS Negl Trop Dis. 2015 Mar 16;9(3):e0003593. doi: 10.1371/journal.pntd.0003593. eCollection 2015 Mar.

27.

The diterpenoid 7-keto-sempervirol, derived from Lycium chinense, displays anthelmintic activity against both Schistosoma mansoni and Fasciola hepatica.

Edwards J, Brown M, Peak E, Bartholomew B, Nash RJ, Hoffmann KF.

PLoS Negl Trop Dis. 2015 Mar 13;9(3):e0003604. doi: 10.1371/journal.pntd.0003604. eCollection 2015 Mar.

28.

Medicine. Halting harmful helminths.

Hoffmann KF, Brindley PJ, Berriman M.

Science. 2014 Oct 10;346(6206):168-9. doi: 10.1126/science.1261139. No abstract available.

PMID:
25301604
29.

Crystal structure of Schistosoma mansoni arginase, a potential drug target for the treatment of schistosomiasis.

Hai Y, Edwards JE, Van Zandt MC, Hoffmann KF, Christianson DW.

Biochemistry. 2014 Jul 22;53(28):4671-84. doi: 10.1021/bi5004519. Epub 2014 Jul 9.

30.

Excreted/secreted Schistosoma mansoni venom allergen-like 9 (SmVAL9) modulates host extracellular matrix remodelling gene expression.

Yoshino TP, Brown M, Wu XJ, Jackson CJ, Ocadiz-Ruiz R, Chalmers IW, Kolb M, Hokke CH, Hoffmann KF.

Int J Parasitol. 2014 Jul;44(8):551-63. doi: 10.1016/j.ijpara.2014.04.002. Epub 2014 May 21.

31.

Cytosine methylation is a conserved epigenetic feature found throughout the phylum Platyhelminthes.

Geyer KK, Chalmers IW, Mackintosh N, Hirst JE, Geoghegan R, Badets M, Brophy PM, Brehm K, Hoffmann KF.

BMC Genomics. 2013 Jul 9;14:462. doi: 10.1186/1471-2164-14-462.

32.

Schistosoma mansoni hemozoin modulates alternative activation of macrophages via specific suppression of Retnla expression and secretion.

Truscott M, Evans DA, Gunn M, Hoffmann KF.

Infect Immun. 2013 Jan;81(1):133-42. doi: 10.1128/IAI.00701-12. Epub 2012 Oct 22.

33.

Platyhelminth Venom Allergen-Like (VAL) proteins: revealing structural diversity, class-specific features and biological associations across the phylum.

Chalmers IW, Hoffmann KF.

Parasitology. 2012 Sep;139(10):1231-45. doi: 10.1017/S0031182012000704. Epub 2012 May 2. Review.

34.

The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses.

Fitzsimmons CM, Jones FM, Stearn A, Chalmers IW, Hoffmann KF, Wawrzyniak J, Wilson S, Kabatereine NB, Dunne DW.

PLoS Negl Trop Dis. 2012;6(4):e1593. doi: 10.1371/journal.pntd.0001593. Epub 2012 Apr 3.

35.

Epigenetics: a key regulator of platyhelminth developmental biology?

Geyer KK, Hoffmann KF.

Int J Parasitol. 2012;42(3):221-4. doi: 10.1016/j.ijpara.2012.02.003. Epub 2012 Feb 17.

PMID:
22366548
36.

Parasite genomics and post-genomic activities: 21st century resources for the parasite immunologist.

Brehm K, Carlton JM, Hoffmann KF.

Parasite Immunol. 2012 Feb-Mar;34(2-3):47-9. doi: 10.1111/j.1365-3024.2011.01346.x. No abstract available.

37.

Schistosoma comparative genomics: integrating genome structure, parasite biology and anthelmintic discovery.

Swain MT, Larkin DM, Caffrey CR, Davies SJ, Loukas A, Skelly PJ, Hoffmann KF.

Trends Parasitol. 2011 Dec;27(12):555-64. doi: 10.1016/j.pt.2011.09.003. Epub 2011 Oct 23. Review.

38.

Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni.

Geyer KK, Rodríguez López CM, Chalmers IW, Munshi SE, Truscott M, Heald J, Wilkinson MJ, Hoffmann KF.

Nat Commun. 2011 Aug 9;2:424. doi: 10.1038/ncomms1433.

39.

Cross-disciplinary approaches for measuring parasitic helminth viability and phenotype.

Peak E, Hoffmann KF.

An Acad Bras Cienc. 2011 Jun;83(2):649-62.

40.

Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability.

Peak E, Chalmers IW, Hoffmann KF.

PLoS Negl Trop Dis. 2010 Jul 27;4(7):e759. doi: 10.1371/journal.pntd.0000759.

41.

Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses.

Fitzpatrick JM, Peak E, Perally S, Chalmers IW, Barrett J, Yoshino TP, Ivens AC, Hoffmann KF.

PLoS Negl Trop Dis. 2009 Nov 3;3(11):e543. doi: 10.1371/journal.pntd.0000543.

42.

Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoni.

Lockyer AE, Spinks J, Kane RA, Hoffmann KF, Fitzpatrick JM, Rollinson D, Noble LR, Jones CS.

BMC Genomics. 2008 Dec 29;9:634. doi: 10.1186/1471-2164-9-634.

43.

Use of genomic DNA as an indirect reference for identifying gender-associated transcripts in morphologically identical, but chromosomally distinct, Schistosoma mansoni cercariae.

Fitzpatrick JM, Protasio AV, McArdle AJ, Williams GA, Johnston DA, Hoffmann KF.

PLoS Negl Trop Dis. 2008;2(10):e323. doi: 10.1371/journal.pntd.0000323. Epub 2008 Oct 22.

44.

Schistosoma mansoni arginase shares functional similarities with human orthologs but depends upon disulphide bridges for enzymatic activity.

Fitzpatrick JM, Fuentes JM, Chalmers IW, Wynn TA, Modolell M, Hoffmann KF, Hesse M.

Int J Parasitol. 2009 Feb;39(3):267-79. doi: 10.1016/j.ijpara.2008.06.015. Epub 2008 Aug 6.

45.

Developmentally regulated expression, alternative splicing and distinct sub-groupings in members of the Schistosoma mansoni venom allergen-like (SmVAL) gene family.

Chalmers IW, McArdle AJ, Coulson RM, Wagner MA, Schmid R, Hirai H, Hoffmann KF.

BMC Genomics. 2008 Feb 23;9:89. doi: 10.1186/1471-2164-9-89.

46.

Schistosome genomics and beyond: news and views.

Grevelding CG, Hoffmann KF.

Exp Parasitol. 2007 Nov;117(3):223-4. Epub 2007 Sep 8. No abstract available.

PMID:
17919581
47.

Glycomics-driven discoveries in schistosome research.

Hokke CH, Deelder AM, Hoffmann KF, Wuhrer M.

Exp Parasitol. 2007 Nov;117(3):275-83. Epub 2007 Jun 17. Review.

PMID:
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