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Items: 1 to 50 of 1202

1.

A network of trans-cortical capillaries as mainstay for blood circulation in long bones.

Grüneboom A, Hawwari I, Weidner D, Culemann S, Müller S, Henneberg S, Brenzel A, Merz S, Bornemann L, Zec K, Wuelling M, Kling L, Hasenberg M, Voortmann S, Lang S, Baum W, Ohs A, Kraff O, Quick HH, Jäger M, Landgraeber S, Dudda M, Danuser R, Stein JV, Rohde M, Gelse K, Garbe AI, Adamczyk A, Westendorf AM, Hoffmann D, Christiansen S, Engel DR, Vortkamp A, Krönke G, Herrmann M, Kamradt T, Schett G, Hasenberg A, Gunzer M.

Nat Metab. 2019 Feb;1(2):236-250. doi: 10.1038/s42255-018-0016-5. Epub 2019 Jan 21.

2.

Hip Fractures: Therapy, Timing, and Complication Spectrum.

Saul D, Riekenberg J, Ammon JC, Hoffmann DB, Sehmisch S.

Orthop Surg. 2019 Sep 30. doi: 10.1111/os.12524. [Epub ahead of print]

PMID:
31568676
3.

Targeted in-vitro-stimulation reveals highly proliferative multi-virus-specific human central memory T cells as candidates for prophylactic T cell therapy.

Faist B, Schlott F, Stemberger C, Dennehy KM, Krackhardt A, Verbeek M, Grigoleit GU, Schiemann M, Hoffmann D, Dick A, Martin K, Hildebrandt M, Busch DH, Neuenhahn M.

PLoS One. 2019 Sep 30;14(9):e0223258. doi: 10.1371/journal.pone.0223258. eCollection 2019.

4.

Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophy.

Wuelling M, Schneider S, Schröther VA, Waterkamp C, Hoffmann D, Vortkamp A.

Dev Biol. 2019 Sep 21. pii: S0012-1606(19)30277-5. doi: 10.1016/j.ydbio.2019.09.012. [Epub ahead of print]

5.

Targeted Repair of p47-CGD in iPSCs by CRISPR/Cas9: Functional Correction without Cleavage in the Highly Homologous Pseudogenes.

Klatt D, Cheng E, Philipp F, Selich A, Dahlke J, Schmidt RE, Schott JW, Büning H, Hoffmann D, Thrasher AJ, Schambach A.

Stem Cell Reports. 2019 Oct 8;13(4):590-598. doi: 10.1016/j.stemcr.2019.08.008. Epub 2019 Sep 19.

6.

Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018.

Pohlmann A, Hoffmann D, Grund C, Koethe S, Hüssy D, Meier SM, King J, Schinköthe J, Ulrich R, Harder T, Beer M.

Emerg Infect Dis. 2019 Oct;25(10):1973-1976. doi: 10.3201/eid2510.181931.

7.

Experimental lumpy skin disease virus infection of cattle: comparison of a field strain and a vaccine strain.

Möller J, Moritz T, Schlottau K, Krstevski K, Hoffmann D, Beer M, Hoffmann B.

Arch Virol. 2019 Sep 19. doi: 10.1007/s00705-019-04411-w. [Epub ahead of print]

PMID:
31538254
8.

The Selective Androgen Receptor Modulator Ostarine Improves Bone Healing in Ovariectomized Rats.

Komrakova M, Furtwängler J, Hoffmann DB, Lehmann W, Schilling AF, Sehmisch S.

Calcif Tissue Int. 2019 Sep 17. doi: 10.1007/s00223-019-00613-1. [Epub ahead of print]

PMID:
31531719
9.

Bat influenza viruses transmit among bats but are poorly adapted to non-bat species.

Ciminski K, Ran W, Gorka M, Lee J, Malmlov A, Schinköthe J, Eckley M, Murrieta RA, Aboellail TA, Campbell CL, Ebel GD, Ma J, Pohlmann A, Franzke K, Ulrich R, Hoffmann D, García-Sastre A, Ma W, Schountz T, Beer M, Schwemmle M.

Nat Microbiol. 2019 Sep 16. doi: 10.1038/s41564-019-0556-9. [Epub ahead of print]

PMID:
31527796
10.

Effect of alendronate or 8-prenylnaringenin applied as a single therapy or in combination with vibration on muscle structure and bone healing in ovariectomized rats.

Komrakova M, Rechholtz C, Pohlmann N, Lehmann W, Schilling AF, Wigger R, Sehmisch S, Hoffmann DB.

Bone Rep. 2019 Aug 27;11:100224. doi: 10.1016/j.bonr.2019.100224. eCollection 2019 Dec.

11.

Common vole (Microtus arvalis) and bank vole (Myodes glareolus) derived permanent cell lines differ in their susceptibility and replication kinetics of animal and zoonotic viruses.

Binder F, Lenk M, Weber S, Stoek F, Dill V, Reiche S, Riebe R, Wernike K, Hoffmann D, Ziegler U, Adler H, Essbauer S, Ulrich RG.

J Virol Methods. 2019 Sep 9:113729. doi: 10.1016/j.jviromet.2019.113729. [Epub ahead of print]

PMID:
31513859
12.

Particle-in-cell simulation of transport and energy deposition of intense proton beams in solid-state materials.

Wu D, Yu W, Zhao YT, Hoffmann DHH, Fritzsche S, He XT.

Phys Rev E. 2019 Jul;100(1-1):013208. doi: 10.1103/PhysRevE.100.013208.

PMID:
31499819
13.

Accuracy of self-referral in health anxiety: comparison of patients self-referring to internet-delivered treatment versus patients clinician-referred to face-to-face treatment.

Hoffmann D, Rask CU, Hedman-Lagerlöf E, Eilenberg T, Frostholm L.

BJPsych Open. 2019 Sep 9;5(5):e80. doi: 10.1192/bjo.2019.54.

14.

Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones.

Schroeder N, Wuelling M, Hoffmann D, Brand-Saberi B, Vortkamp A.

PLoS One. 2019 Aug 26;14(8):e0218230. doi: 10.1371/journal.pone.0218230. eCollection 2019.

15.

Capsid Engineering Overcomes Barriers Toward Adeno-Associated Virus Vector-Mediated Transduction of Endothelial Cells.

Zhang L, Rossi A, Lange L, Meumann N, Koitzsch U, Christie K, Nesbit MA, Moore CBT, Hacker UT, Morgan M, Hoffmann D, Zengel J, Carette JE, Schambach A, Salvetti A, Odenthal M, Büning H.

Hum Gene Ther. 2019 Oct;30(10):1284-1296. doi: 10.1089/hum.2019.027.

PMID:
31407607
16.

Generation of recombinant MVA-norovirus: a comparison study of bacterial artificial chromosome- and marker-based systems.

Kugler F, Drexler I, Protzer U, Hoffmann D, Moeini H.

Virol J. 2019 Aug 9;16(1):100. doi: 10.1186/s12985-019-1212-y.

17.

Distribution of zoonotic variegated squirrel bornavirus 1 in naturally infected variegated and Prevost's squirrels.

Petzold J, van den Brand JMA, Nobach D, Hoffmann B, Hoffmann D, Fast C, Reusken CBEM, van Run PRWA, Schlottau K, Beer M, Herden C.

Sci Rep. 2019 Aug 6;9(1):11402. doi: 10.1038/s41598-019-47767-4.

18.

Steroids originating from bacterial bile acid degradation affect Caenorhabditis elegans and indicate potential risks for the fauna of manured soils.

Mendelski MN, Dölling R, Feller FM, Hoffmann D, Ramos Fangmeier L, Ludwig KC, Yücel O, Mährlein A, Paul RJ, Philipp B.

Sci Rep. 2019 Jul 31;9(1):11120. doi: 10.1038/s41598-019-47476-y.

19.

Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.

Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM.

Nature. 2019 Aug;572(7769):E18. doi: 10.1038/s41586-019-1459-x.

PMID:
31363232
20.

Changes in Musculoskeletal System and Metabolism in Osteoporotic Rats Treated With Urocortin.

Saul D, Geisberg LK, Gehle T, Hoffmann DB, Tezval M, Sehmisch S, Komrakova M.

Front Endocrinol (Lausanne). 2019 Jun 24;10:400. doi: 10.3389/fendo.2019.00400. eCollection 2019.

21.

Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy.

Uribesalgo I, Hoffmann D, Zhang Y, Kavirayani A, Lazovic J, Berta J, Novatchkova M, Pai TP, Wimmer RA, László V, Schramek D, Karim R, Tortola L, Deswal S, Haas L, Zuber J, Szűcs M, Kuba K, Dome B, Cao Y, Haubner BJ, Penninger JM.

EMBO Mol Med. 2019 Aug;11(8):e9266. doi: 10.15252/emmm.201809266. Epub 2019 Jun 24.

22.

Association of Cortical Stimulation-Induced Seizure With Surgical Outcome in Patients With Focal Drug-Resistant Epilepsy.

Cuello Oderiz C, von Ellenrieder N, Dubeau F, Eisenberg A, Gotman J, Hall J, Hincapié AS, Hoffmann D, Job AS, Khoo HM, Minotti L, Olivier A, Kahane P, Frauscher B.

JAMA Neurol. 2019 Jun 10. doi: 10.1001/jamaneurol.2019.1464. [Epub ahead of print]

PMID:
31180505
23.

Implementing volunteer peer mentoring as a supplement to professional efforts in primary rehabilitation of persons with spinal cord injury.

Hoffmann DD, Sundby J, Biering-Sørensen F, Kasch H.

Spinal Cord. 2019 Oct;57(10):881-889. doi: 10.1038/s41393-019-0294-0. Epub 2019 May 23.

PMID:
31123334
24.

[Patellar dislocation in children and adolescents : Current developments in diagnostics and treatment].

Obermeyer C, Hoffmann DB, Wachowski MM.

Orthopade. 2019 Oct;48(10):868-876. doi: 10.1007/s00132-019-03754-1. Review. German.

PMID:
31101964
25.

First detection of TBE virus in ticks and sero-reactivity in goats in a non-endemic region in the southern part of Switzerland (Canton of Ticino).

Casati Pagani S, Frigerio Malossa S, Klaus C, Hoffmann D, Beretta O, Bomio-Pacciorini N, Lazzaro M, Merlani G, Ackermann R, Beuret C.

Ticks Tick Borne Dis. 2019 Jun;10(4):868-874. doi: 10.1016/j.ttbdis.2019.04.006. Epub 2019 Apr 18.

PMID:
31047827
26.

Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly: Recent Advances and Perspectives.

Yang L, Liu F, Tong X, Hoffmann D, Zuo J, Lu M.

ACS Infect Dis. 2019 May 10;5(5):713-724. doi: 10.1021/acsinfecdis.8b00337. Epub 2019 Mar 29.

PMID:
30896149
27.

Stock price effects of breakthrough therapy designation.

Hoffmann D, Van Dalsem S, David FS.

Nat Rev Drug Discov. 2019 Mar;18(3):165. doi: 10.1038/d41573-019-00019-6. No abstract available.

PMID:
30824891
28.

Gut microbiota of the European Brown Hare (Lepus europaeus).

Stalder GL, Pinior B, Zwirzitz B, Loncaric I, Jakupović D, Vetter SG, Smith S, Posautz A, Hoelzl F, Wagner M, Hoffmann D, Kübber-Heiss A, Mann E.

Sci Rep. 2019 Feb 25;9(1):2738. doi: 10.1038/s41598-019-39638-9.

29.

MHC class II proteins mediate cross-species entry of bat influenza viruses.

Karakus U, Thamamongood T, Ciminski K, Ran W, Günther SC, Pohl MO, Eletto D, Jeney C, Hoffmann D, Reiche S, Schinköthe J, Ulrich R, Wiener J, Hayes MGB, Chang MW, Hunziker A, Yángüez E, Aydillo T, Krammer F, Oderbolz J, Meier M, Oxenius A, Halenius A, Zimmer G, Benner C, Hale BG, García-Sastre A, Beer M, Schwemmle M, Stertz S.

Nature. 2019 Mar;567(7746):109-112. doi: 10.1038/s41586-019-0955-3. Epub 2019 Feb 20.

PMID:
30787439
30.

Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level.

Karimzadeh H, Kiraithe MM, Oberhardt V, Salimi Alizei E, Bockmann J, Schulze Zur Wiesch J, Budeus B, Hoffmann D, Wedemeyer H, Cornberg M, Krawczyk A, Rashidi-Alavijeh J, Rodríguez-Frías F, Casillas R, Buti M, Smedile A, Alavian SM, Heinold A, Emmerich F, Panning M, Gostick E, Price DA, Timm J, Hofmann M, Raziorrouh B, Thimme R, Protzer U, Roggendorf M, Neumann-Haefelin C.

Gastroenterology. 2019 May;156(6):1820-1833. doi: 10.1053/j.gastro.2019.02.003. Epub 2019 Feb 12.

31.

A mind-brain-body dataset of MRI, EEG, cognition, emotion, and peripheral physiology in young and old adults.

Babayan A, Erbey M, Kumral D, Reinelt JD, Reiter AMF, Röbbig J, Schaare HL, Uhlig M, Anwander A, Bazin PL, Horstmann A, Lampe L, Nikulin VV, Okon-Singer H, Preusser S, Pampel A, Rohr CS, Sacher J, Thöne-Otto A, Trapp S, Nierhaus T, Altmann D, Arelin K, Blöchl M, Bongartz E, Breig P, Cesnaite E, Chen S, Cozatl R, Czerwonatis S, Dambrauskaite G, Dreyer M, Enders J, Engelhardt M, Fischer MM, Forschack N, Golchert J, Golz L, Guran CA, Hedrich S, Hentschel N, Hoffmann DI, Huntenburg JM, Jost R, Kosatschek A, Kunzendorf S, Lammers H, Lauckner ME, Mahjoory K, Kanaan AS, Mendes N, Menger R, Morino E, Näthe K, Neubauer J, Noyan H, Oligschläger S, Panczyszyn-Trzewik P, Poehlchen D, Putzke N, Roski S, Schaller MC, Schieferbein A, Schlaak B, Schmidt R, Gorgolewski KJ, Schmidt HM, Schrimpf A, Stasch S, Voss M, Wiedemann A, Margulies DS, Gaebler M, Villringer A.

Sci Data. 2019 Feb 12;6:180308. doi: 10.1038/sdata.2018.308.

32.

Massage and Medicine: An Interprofessional Approach to Learning Musculoskeletal Anatomy and Enhancing Personal Wellness.

Hoffmann DS, Dancing D, Rosenbaum M.

Acad Med. 2019 Jun;94(6):885-892. doi: 10.1097/ACM.0000000000002623.

PMID:
30720530
33.

Chickens' growth performance and pancreas development exposed to soy cake varying in trypsin inhibitor activity, heat-degraded lysine concentration, and protein solubility in potassium hydroxide.

Hoffmann D, Thurner S, Ankerst D, Damme K, Windisch W, Brugger D.

Poult Sci. 2019 Jun 1;98(6):2489-2499. doi: 10.3382/ps/pey592.

PMID:
30668825
34.

Effect of the lipoxygenase inhibitor baicalein on bone tissue and bone healing in ovariectomized rats.

Saul D, Weber M, Zimmermann MH, Kosinsky RL, Hoffmann DB, Menger B, Taudien S, Lehmann W, Komrakova M, Sehmisch S.

Nutr Metab (Lond). 2019 Jan 11;16:4. doi: 10.1186/s12986-018-0327-2. eCollection 2019.

35.

An examination of food parenting practices: structure, control and autonomy promotion.

Musher-Eizenman DR, Goodman L, Roberts L, Marx J, Taylor M, Hoffmann D.

Public Health Nutr. 2018 Dec 18:1-13. doi: 10.1017/S1368980018003312. [Epub ahead of print]

PMID:
30561294
36.

First record and morphological characterization of an established population of Aedes (Hulecoeteomyia) koreicus (Diptera: Culicidae) in Germany.

Pfitzner WP, Lehner A, Hoffmann D, Czajka C, Becker N.

Parasit Vectors. 2018 Dec 17;11(1):662. doi: 10.1186/s13071-018-3199-4.

37.

Reaction kinetics of ultracold molecule-molecule collisions.

Hoffmann DK, Paintner T, Limmer W, Petrov DS, Denschlag JH.

Nat Commun. 2018 Dec 7;9(1):5244. doi: 10.1038/s41467-018-07576-1.

38.

Downstream processing of Cry4AaCter-induced inclusion bodies containing insect-derived antimicrobial peptides produced in Escherichia coli.

Hoffmann D, Eckhardt D, Gerlach D, Vilcinskas A, Czermak P.

Protein Expr Purif. 2019 Mar;155:120-129. doi: 10.1016/j.pep.2018.12.002. Epub 2018 Dec 4.

39.

A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitude.

Gigante A, Grad JN, Briels J, Bartel M, Hoffmann D, Ottmann C, Schmuck C.

Chem Commun (Camb). 2018 Dec 18;55(1):111-114. doi: 10.1039/c8cc07946c.

PMID:
30515494
40.

The therapeutic potential of the insect metalloproteinase inhibitor against infections caused by Pseudomonas aeruginosa.

Eisenhardt M, Schlupp P, Höfer F, Schmidts T, Hoffmann D, Czermak P, Pöppel AK, Vilcinskas A, Runkel F.

J Pharm Pharmacol. 2019 Mar;71(3):316-328. doi: 10.1111/jphp.13034. Epub 2018 Nov 8.

PMID:
30408181
41.

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.

Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM.

Nature. 2018 Nov;563(7732):564-568. doi: 10.1038/s41586-018-0701-2. Epub 2018 Nov 7. Erratum in: Nature. 2019 Aug;572(7769):E18.

42.

Human Teratoma-Derived Hematopoiesis Is a Highly Polyclonal Process Supported by Human Umbilical Vein Endothelial Cells.

Philipp F, Selich A, Rothe M, Hoffmann D, Rittinghausen S, Morgan MA, Klatt D, Glage S, Lienenklaus S, Neuhaus V, Sewald K, Braun A, Schambach A.

Stem Cell Reports. 2018 Nov 13;11(5):1051-1060. doi: 10.1016/j.stemcr.2018.09.010. Epub 2018 Oct 18.

43.

Response to Comment on "U-Th dating of carbonate crusts reveals Neandertal origin of Iberian cave art".

Hoffmann DL, Standish CD, García-Diez M, Pettitt PB, Milton JA, Zilhão J, Alcolea-González JJ, Cantalejo-Duarte P, Collado H, de Balbín R, Lorblanchet M, Ramos-Muñoz J, Weniger GC, Pike AWG.

Science. 2018 Oct 12;362(6411). pii: eaau1736. doi: 10.1126/science.aau1736.

PMID:
30309914
44.

The authors reply.

C von Rosenvinge E, Palumbo F, Ravel J, Rowthorn V, Hoffmann D.

Gut Microbes. 2019;10(2):113-114. doi: 10.1080/19490976.2018.1516980. Epub 2018 Oct 5.

45.

Fatal Encephalitic Borna Disease Virus 1 in Solid-Organ Transplant Recipients.

Schlottau K, Forth L, Angstwurm K, Höper D, Zecher D, Liesche F, Hoffmann B, Kegel V, Seehofer D, Platen S, Salzberger B, Liebert UG, Niller HH, Schmidt B, Matiasek K, Riemenschneider MJ, Brochhausen C, Banas B, Renders L, Moog P, Wunderlich S, Seifert CL, Barreiros A, Rahmel A, Weiss J, Tappe D, Herden C, Schmidt-Chanasit J, Schwemmle M, Rubbenstroth D, Schlegel J, Pietsch C, Hoffmann D, Jantsch J, Beer M.

N Engl J Med. 2018 Oct 4;379(14):1377-1379. doi: 10.1056/NEJMc1803115. No abstract available.

PMID:
30281984
46.

SynAggreg: A Multifunctional High-Throughput Technology for Precision Study of Amyloid Aggregation and Systematic Discovery of Synergistic Inhibitor Compounds.

Aviolat H, Nominé Y, Gioria S, Bonhoure A, Hoffmann D, Ruhlmann C, Nierengarten H, Ruffenach F, Villa P, Trottier Y, Klein FAC.

J Mol Biol. 2018 Dec 7;430(24):5257-5279. doi: 10.1016/j.jmb.2018.09.009. Epub 2018 Sep 25.

PMID:
30266595
47.

Differential escape of HCV from CD8+ T cell selection pressure between China and Germany depends on the presenting HLA class I molecule.

Xia Y, Pan W, Ke X, Skibbe K, Walker A, Hoffmann D, Lu Y, Yang X, Feng X, Tong Q, Timm J, Yang D.

J Viral Hepat. 2019 Jan;26(1):73-82. doi: 10.1111/jvh.13011. Epub 2018 Nov 28.

PMID:
30260541
48.

Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart Disease.

Kehrmann J, Menzel J, Saeedghalati M, Obeid R, Schulze C, Holzendorf V, Farahpour F, Reinsch N, Klein-Hitpass L, Streeck H, Hoffmann D, Buer J, Esser S; HIV-HEART Study Group.

J Infect Dis. 2019 Jan 9;219(3):497-508. doi: 10.1093/infdis/jiy524.

PMID:
30202890
49.

Evaluation of susceptibility of HIV-1 CRF01_AE variants to neutralization by a panel of broadly neutralizing antibodies.

Wang H, Yuan T, Li T, Li Y, Qian F, Zhu C, Liang S, Hoffmann D, Dittmer U, Sun B, Yang R.

Arch Virol. 2018 Dec;163(12):3303-3315. doi: 10.1007/s00705-018-4011-7. Epub 2018 Sep 8.

PMID:
30196320
50.

Effects of RANKL Knockdown by Virus-like Particle-Mediated RNAi in a Rat Model of Osteoporosis.

Hoffmann DB, Gruber J, Böker KO, Deppe D, Sehmisch S, Schilling AF, Lemus-Diaz N, Komrakova M, Schneider S.

Mol Ther Nucleic Acids. 2018 Sep 7;12:443-452. doi: 10.1016/j.omtn.2018.06.001. Epub 2018 Jul 11.

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