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Structural insight into small molecule action on Frizzleds.

Kozielewicz P, Turku A, Bowin CF, Petersen J, Valnohova J, Cañizal MCA, Ono Y, Inoue A, Hoffmann C, Schulte G.

Nat Commun. 2020 Jan 21;11(1):414. doi: 10.1038/s41467-019-14149-3.


Tracking Short-Range Attraction and Oviposition of European Grapevine Moths Affected by Volatile Organic Compounds in a Four-Chamber Olfactometer.

Markheiser A, Rid M, Biancu S, Gross J, Hoffmann C.

Insects. 2020 Jan 8;11(1). pii: E45. doi: 10.3390/insects11010045.


SorCS2 facilitates release of endostatin from astrocytes and controls post-stroke angiogenesis.

Malik AR, Lips J, Gorniak-Walas M, Broekaart DWM, Asaro A, Kuffner MTC, Hoffmann CJ, Kikhia M, Dopatka M, Boehm-Sturm P, Mueller S, Dirnagl U, Aronica E, Harms C, Willnow TE.

Glia. 2020 Jan 3. doi: 10.1002/glia.23778. [Epub ahead of print]


Characteristics of the Voice of Dysphonic School Children from 4:0 to 7:11 Years Old.

Hoffmann CF, Cielo CA.

J Voice. 2019 Dec 27. pii: S0892-1997(19)30516-8. doi: 10.1016/j.jvoice.2019.12.004. [Epub ahead of print]


Perinatal mortality: epidemiological profile, causes and avoidable factors at a reference public maternity hospital in the State of Santa Catarina, Brazil, 2011-2015.

Hoffmann CBPC, Schultz LF, Vaichulonis CG, do Nascimento IB, João CG, Borges DC, Silva JC.

J Perinat Med. 2019 Dec 25. pii: /j/jpme.ahead-of-print/jpm-2018-0353/jpm-2018-0353.xml. doi: 10.1515/jpm-2018-0353. [Epub ahead of print]


Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study.

Dépret F, Hoffmann C, Daoud L, Thieffry C, Monplaisir L, Creveaux J, Annane D, Parmentier E, Mathieu D, Wiramus S, Demeure DIt Latte D, Kpodji A, Textoris J, Robin F, Klouche K, Pontis E, Schnell G, Barbier F, Constantin JM, Clavier T, du Cheyron D, Terzi N, Sauneuf B, Guerot E, Lafon T, Herbland A, Megarbane B, Leclerc T, Mallet V, Pirracchio R, Legrand M.

Crit Care. 2019 Dec 23;23(1):421. doi: 10.1186/s13054-019-2706-0.


Helix 8 is the essential structural motif of mechanosensitive GPCRs.

Erdogmus S, Storch U, Danner L, Becker J, Winter M, Ziegler N, Wirth A, Offermanns S, Hoffmann C, Gudermann T, Mederos Y Schnitzler M.

Nat Commun. 2019 Dec 19;10(1):5784. doi: 10.1038/s41467-019-13722-0.


Rationale, design, and development of SleepWell24: A smartphone application to promote adherence to positive airway pressure therapy among patients with obstructive sleep apnea.

Petrov ME, Hasanaj K, Hoffmann CM, Epstein DR, Krahn L, Park JG, Hollingshead K, Yu TY, Todd M, St Louis EK, Morgenthaler TI, Buman MP.

Contemp Clin Trials. 2019 Dec 14;89:105908. doi: 10.1016/j.cct.2019.105908. [Epub ahead of print]


The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo.

Weber S, Koschade SE, Hoffmann CM, Dubash TD, Giessler KM, Dieter SM, Herbst F, Glimm H, Ball CR.

BMC Cancer. 2019 Dec 3;19(1):1181. doi: 10.1186/s12885-019-6396-4.


Absence of Autoantibodies Against Neuronal Surface Antigens in Sera of Patients With Psychotic Disorders.

Hoffmann C, Zong S, Mané-Damas M, Molenaar PC, Losen M, Titulaer MJ, Martinez-Martinez P; European Consortium of Autoimmune Mental Disorders.

JAMA Psychiatry. 2019 Nov 20. doi: 10.1001/jamapsychiatry.2019.3679. [Epub ahead of print] No abstract available.


Immediate versus deferred antiretroviral therapy in HIV-infected patients presenting with acute AIDS-defining events (toxoplasmosis, Pneumocystis jirovecii-pneumonia): a prospective, randomized, open-label multicenter study (IDEAL-study).

Schäfer G, Hoffmann C, Arasteh K, Schürmann D, Stephan C, Jensen B, Stoll M, Bogner JR, Faetkenheuer G, Rockstroh J, Klinker H, Härter G, Stöhr A, Degen O, Freiwald E, Hüfner A, Jordan S, Schulze Zur Wiesch J, Addo M, Lohse AW, van Lunzen J, Schmiedel S; IDEAL study group.

AIDS Res Ther. 2019 Nov 15;16(1):34. doi: 10.1186/s12981-019-0250-2.


[Legal pitfalls in urology].

Hoffmann C, Süfke C, Gross A.

Urologe A. 2020 Jan;59(1):87-98. doi: 10.1007/s00120-019-01060-4. German.


Algorithm-guided empirical tuberculosis treatment for people with advanced HIV (TB Fast Track): an open-label, cluster-randomised trial.

Grant AD, Charalambous S, Tlali M, Karat AS, Dorman SE, Hoffmann CJ, Johnson S, Vassall A, Churchyard GJ, Fielding KL.

Lancet HIV. 2020 Jan;7(1):e27-e37. doi: 10.1016/S2352-3018(19)30266-8. Epub 2019 Nov 11.


Maximum Phonation Time and Body Mass Index in Nondysphonic Eutrophic Children.

Finger LS, Hoffmann CF, Cielo CA.

J Voice. 2019 Nov 1. pii: S0892-1997(19)30295-4. doi: 10.1016/j.jvoice.2019.09.018. [Epub ahead of print]


The Human Milk Microbiota is Modulated by Maternal Diet.

Padilha M, Danneskiold-Samsøe NB, Brejnrod A, Hoffmann C, Cabral VP, Iaucci JM, Sales CH, Fisberg RM, Cortez RV, Brix S, Taddei CR, Kristiansen K, Saad SMI.

Microorganisms. 2019 Oct 29;7(11). pii: E502. doi: 10.3390/microorganisms7110502.


Stimulation challenge test after STN DBS improves satisfaction in Parkinson's disease patients.

Geraedts VJ, van Hilten JJ, Marinus J, Mosch A, Naarding KJ, Hoffmann CFE, van der Gaag NA, Contarino MF.

Parkinsonism Relat Disord. 2019 Dec;69:30-33. doi: 10.1016/j.parkreldis.2019.10.014. Epub 2019 Oct 15.


Prenatal diagnosis of congenital head, face, and neck malformations-Is complementary fetal MRI of value?

Zemet R, Amdur-Zilberfarb I, Shapira M, Ziv-Baran T, Hoffmann C, Kassif E, Katorza E.

Prenat Diagn. 2019 Oct 30. doi: 10.1002/pd.5593. [Epub ahead of print]


Bringing fear into focus: The intersections of HIV and masculine gender norms in Côte d'Ivoire.

Naugle DA, Tibbels NJ, Hendrickson ZM, Dosso A, Van Lith L, Mallalieu EC, Kouadio AM, Kra W, Kamara D, Dailly-Ajavon P, Cissé A, Seifert-Ahanda K, Thaddeus S, Babalola S, Hoffmann CJ.

PLoS One. 2019 Oct 23;14(10):e0223414. doi: 10.1371/journal.pone.0223414. eCollection 2019.


Controlled exploration of chemical space by machine learning of coarse-grained representations.

Hoffmann C, Menichetti R, Kanekal KH, Bereau T.

Phys Rev E. 2019 Sep;100(3-1):033302. doi: 10.1103/PhysRevE.100.033302.


Isoniazid Preventive Therapy and Pregnancy Outcomes In HIV-Infected Women in the Tshepiso Cohort.

Salazar-Austin N, Cohn S, Lala S, Waja Z, Dooley KE, Hoffmann CJ, Chaisson RE, Martinson N; TSHEPISO Study Team .

Clin Infect Dis. 2019 Oct 21. pii: ciz1024. doi: 10.1093/cid/ciz1024. [Epub ahead of print]


Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish.

Burczyk MS, Burkhalter MD, Tena TC, Grisanti LA, Kauk M, Matysik S, Donow C, Kustermann M, Rothe M, Cui Y, Raad F, Laue S, Moretti A, Zimmermann WH, Wess J, Kühl M, Hoffmann C, Tilley DG, Philipp M.

JCI Insight. 2019 Oct 17;4(20). pii: 121971. doi: 10.1172/jci.insight.121971.


HIV testing services in healthcare facilities in South Africa: a missed opportunity.

Mabuto T, Hansoti B, Kerrigan D, Mshweshwe-Pakela N, Kubeka G, Charalambous S, Hoffmann C.

J Int AIDS Soc. 2019 Oct;22(10):e25367. doi: 10.1002/jia2.25367.


Immune gene expression in head and neck squamous cell carcinoma patients.

Lecerf C, Kamal M, Vacher S, Chemlali W, Schnitzler A, Morel C, Dubot C, Jeannot E, Meseure D, Klijanienko J, Mariani O, Borcoman E, Calugaru V, Badois N, Chilles A, Lesnik M, Krhili S, Choussy O, Hoffmann C, Piaggio E, Bieche I, Le Tourneau C.

Eur J Cancer. 2019 Nov;121:210-223. doi: 10.1016/j.ejca.2019.08.028. Epub 2019 Oct 5.


Thermodynamic and kinetic studies of H2 and N2 binding to bimetallic nickel-group 13 complexes and neutron structure of a Ni(η2-H2) adduct.

Cammarota RC, Xie J, Burgess SA, Vollmer MV, Vogiatzis KD, Ye J, Linehan JC, Appel AM, Hoffmann C, Wang X, Young VG Jr, Lu CC.

Chem Sci. 2019 Jun 10;10(29):7029-7042. doi: 10.1039/c9sc02018g. eCollection 2019 Aug 7.


Patent Foramen Ovale and Ischemic Stroke in Patients With Pulmonary Embolism.

Le Moigne E, Jobic Y, Timsit S, Hoffmann C, Couturaud F.

Ann Intern Med. 2019 Oct 1;171(7):527-528. doi: 10.7326/L19-0479. No abstract available.


An overview of the current progress, challenges, and prospects of human biomonitoring and exposome studies.

Bocato MZ, Bianchi Ximenez JP, Hoffmann C, Barbosa F.

J Toxicol Environ Health B Crit Rev. 2019;22(5-6):131-156. doi: 10.1080/10937404.2019.1661588. Epub 2019 Sep 5.


Spectroscopic Studies of the Magnetic Excitation and Spin-Phonon Couplings in a Single-Molecule Magnet.

Stavretis SE, Moseley DH, Fei F, Cui HH, Cheng Y, Podlesnyak AA, Wang X, Daemen LL, Hoffmann CM, Ozerov M, Lu Z, Thirunavukkuarasu K, Smirnov D, Chang T, Chen YS, Ramirez-Cuesta AJ, Chen XT, Xue ZB.

Chemistry. 2019 Dec 10;25(69):15846-15857. doi: 10.1002/chem.201903635. Epub 2019 Nov 14.


Acellular fish skin matrix on thin-skin graft donor sites: a preliminary study.

Badois N, Bauër P, Cheron M, Hoffmann C, Nicodeme M, Choussy O, Lesnik M, Poitrine FC, Fromantin I.

J Wound Care. 2019 Sep 2;28(9):624-628. doi: 10.12968/jowc.2019.28.9.624.


Cerebral and portal vein thrombosis, macrocephaly and atypical absence seizures in Glycosylphosphatidyl inositol deficiency due to a PIGM promoter mutation.

Pode-Shakked B, Heimer G, Vilboux T, Marek-Yagel D, Ben-Zeev B, Davids M, Ferreira CR, Philosoph AM, Veber A, Pode-Shakked N, Kenet G, Soudack M, Hoffmann C, Vernitsky H, Safaniev M, Lodzki M, Lahad A, Shouval DS, Levinkopf D, Weiss B, Barg AA, Daka A, Amariglio N, Malicdan MCV, Gahl WA, Anikster Y.

Mol Genet Metab. 2019 Sep - Oct;128(1-2):151-161. doi: 10.1016/j.ymgme.2019.08.003. Epub 2019 Aug 14.


Vascular medicine residents lack adequate training for limb pressure measurement: A nationwide survey in France.

Lanéelle D, Hoffmann C, Stivalet O, Omarjee L, Mahé G.

Vasc Med. 2019 Oct;24(5):452-454. doi: 10.1177/1358863X19867759. Epub 2019 Aug 23. No abstract available.


Improved Protein Inference from Multiple Protease Bottom-Up Mass Spectrometry Data.

Miller RM, Millikin RJ, Hoffmann CV, Solntsev SK, Sheynkman GM, Shortreed MR, Smith LM.

J Proteome Res. 2019 Sep 6;18(9):3429-3438. doi: 10.1021/acs.jproteome.9b00330. Epub 2019 Aug 23.


"You Take Medications, You Live Normally": The Role of Antiretroviral Therapy in Mitigating Men's Perceived Threats of HIV in Côte d'Ivoire.

Hendrickson ZM, Naugle DA, Tibbels N, Dosso A, M Van Lith L, Mallalieu EC, Kamara D, Dailly-Ajavon P, Cisse A, Seifert Ahanda K, Thaddeus S, Babalola S, Hoffmann CJ.

AIDS Behav. 2019 Sep;23(9):2600-2609. doi: 10.1007/s10461-019-02614-5.


Doravirine dose selection and 96-week safety and efficacy versus efavirenz in antiretroviral therapy-naive adults with HIV-1 infection in a Phase IIb trial.

Gatell JM, Morales-Ramirez JO, Hagins DP, Thompson M, Arastéh K, Hoffmann C, Raffi F, Osiyemi O, Dretler R, Harvey C, Xu X, Plettenberg A, Smith DE, Portilla J, Rugina S, Kumar S, Frobose C, Wan H, Rodgers A, Hwang C, Teppler H.

Antivir Ther. 2019;24(6):425-435. doi: 10.3851/IMP3323.


Autoimmunity in psychotic disorders. Where we stand, challenges and opportunities.

Mané-Damas M, Hoffmann C, Zong S, Tan A, Molenaar PC, Losen M, Martinez-Martinez P.

Autoimmun Rev. 2019 Sep;18(9):102348. doi: 10.1016/j.autrev.2019.102348. Epub 2019 Jul 16. Review.


Purinergic P2Y2 receptors modulate endothelial sprouting.

Mühleder S, Fuchs C, Basílio J, Szwarc D, Pill K, Labuda K, Slezak P, Siehs C, Pröll J, Priglinger E, Hoffmann C, Junger WG, Redl H, Holnthoner W.

Cell Mol Life Sci. 2019 Jul 5. doi: 10.1007/s00018-019-03213-2. [Epub ahead of print]


Readmission and death following hospitalization among people with HIV in South Africa.

Hoffmann CJ, Milovanovic M, Cichowitz C, Kinghorn A, Martinson NA, Variava E.

PLoS One. 2019 Jul 3;14(7):e0218902. doi: 10.1371/journal.pone.0218902. eCollection 2019.


Chemokine Receptor Crystal Structures: What Can Be Learned from Them?

Arimont M, Hoffmann C, de Graaf C, Leurs R.

Mol Pharmacol. 2019 Dec;96(6):765-777. doi: 10.1124/mol.119.117168. Epub 2019 Jul 2.


Gut microbiota is associated with adiposity markers and probiotics may impact specific genera.

Gomes AC, Hoffmann C, Mota JF.

Eur J Nutr. 2019 Jun 27. doi: 10.1007/s00394-019-02034-0. [Epub ahead of print]


"It's Not Like Taking Chocolates": Factors Influencing the Feasibility and Sustainability of Universal Test and Treat in Correctional Health Systems in Zambia and South Africa.

Topp SM, Chetty-Makkan CM, Smith HJ, Chimoyi L, Hoffmann CJ, Fielding K, Reid SE, Olivier AJ, Hausler H, Herce ME, Charalambous S.

Glob Health Sci Pract. 2019 Jun 27;7(2):189-202. doi: 10.9745/GHSP-D-19-00051. Print 2019 Jun.


Linking bioenergetic function of mitochondria to tissue-specific molecular fingerprints.

Kappler L, Hoene M, Hu C, von Toerne C, Li J, Bleher D, Hoffmann C, Böhm A, Kollipara L, Zischka H, Königsrainer A, Häring HU, Peter A, Xu G, Sickmann A, Hauck SM, Weigert C, Lehmann R.

Am J Physiol Endocrinol Metab. 2019 Aug 1;317(2):E374-E387. doi: 10.1152/ajpendo.00088.2019. Epub 2019 Jun 18.


Association of Mycoplasma Hominis and head and neck cancer with unknown primary.

Atallah S, Berçot B, Laurence V, Hoffmann C.

Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Jun 8. pii: S1879-7296(19)30112-7. doi: 10.1016/j.anorl.2019.05.020. [Epub ahead of print]


Tropical rainforest flies carrying pathogens form stable associations with social nonhuman primates.

Gogarten JF, Düx A, Mubemba B, Pléh K, Hoffmann C, Mielke A, Müller-Tiburtius J, Sachse A, Wittig RM, Calvignac-Spencer S, Leendertz FH.

Mol Ecol. 2019 Sep;28(18):4242-4258. doi: 10.1111/mec.15145. Epub 2019 Jul 18.


Re-thinking Linkage to Care in the Era of Universal Test and Treat: Insights from Implementation and Behavioral Science for Achieving the Second 90.

Herce ME, Chi BH, Liao RC, Hoffmann CJ.

AIDS Behav. 2019 Sep;23(Suppl 2):120-128. doi: 10.1007/s10461-019-02541-5. Erratum in: AIDS Behav. 2019 Jul 31;:.


Intraoperative test stimulation of the subthalamic nucleus aids postoperative programming of chronic stimulation settings in Parkinson's disease.

Geraedts VJ, van Ham RAP, Marinus J, van Hilten JJ, Mosch A, Hoffmann CFE, van der Gaag NA, Contarino MF.

Parkinsonism Relat Disord. 2019 Aug;65:62-66. doi: 10.1016/j.parkreldis.2019.05.017. Epub 2019 May 11.


A very potent factor V inhibitor interferes with the levels of all coagulation factors and causes a fatal hemorrhagic syndrome.

Hoffmann C, Amiral J, Rezig S, Kerspern H, Jantzem H, Robin S, Collins A, Mornet C, Mingant F, Pan Petesch B, Ianotto JC, Lippert E, Galinat H.

Eur J Haematol. 2019 Aug;103(2):137-139. doi: 10.1111/ejh.13249. Epub 2019 May 28.


Actin Cytoskeleton Straddling the Immunological Synapse between Cytotoxic Lymphocytes and Cancer Cells.

Wurzer H, Hoffmann C, Al Absi A, Thomas C.

Cells. 2019 May 16;8(5). pii: E463. doi: 10.3390/cells8050463. Review.


Immunomodulatory activity of β-glucan-containing exopolysaccharides from Auricularia auricular in phagocytes and mice infected with Cryptococcus neoformans.

Basso AMM, De Castro RJA, de Castro TB, Guimarães HI, Polez VLP, Carbonero ER, Pomin VH, Hoffmann C, Grossi-de-Sa MF, Tavares AH, Bocca AL.

Med Mycol. 2020 Feb 1;58(2):227-239. doi: 10.1093/mmy/myz042.


Effects of dietary exogenous fibrolytic enzymes on ruminal fermentation characteristics of beef steers fed high- and low-quality growing diets1.

Kondratovich LB, Sarturi JO, Hoffmann CA, Ballou MA, Trojan SJ, Campanili PRB.

J Anim Sci. 2019 Jul 2;97(7):3089-3102. doi: 10.1093/jas/skz165.


Context-Dependent Signaling of CXC Chemokine Receptor 4 and Atypical Chemokine Receptor 3.

Heuninck J, Perpiñá Viciano C, Işbilir A, Caspar B, Capoferri D, Briddon SJ, Durroux T, Hill SJ, Lohse MJ, Milligan G, Pin JP, Hoffmann C.

Mol Pharmacol. 2019 Dec;96(6):778-793. doi: 10.1124/mol.118.115477. Epub 2019 May 15.


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